CA2423837A1 - Small volume in vitro analyte sensor and methods - Google Patents

Small volume in vitro analyte sensor and methods Download PDF

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Publication number
CA2423837A1
CA2423837A1 CA002423837A CA2423837A CA2423837A1 CA 2423837 A1 CA2423837 A1 CA 2423837A1 CA 002423837 A CA002423837 A CA 002423837A CA 2423837 A CA2423837 A CA 2423837A CA 2423837 A1 CA2423837 A1 CA 2423837A1
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CA
Canada
Prior art keywords
methods
small volume
sensor
analyte
charge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002423837A
Other languages
French (fr)
Other versions
CA2423837C (en
Inventor
Charles T. Liamos
Benjamin J. Feldman
Jeffrey V. Funderburk
Rajesh Krishnan
Phillip J. Plante
Joseph A. Vivolo
Robert Y. Jin
Michael S. Cloud
Fredric C. Colman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Therasense Inc
Original Assignee
Therasense, Inc.
Charles T. Liamos
Benjamin J. Feldman
Jeffrey V. Funderburk
Rajesh Krishnan
Phillip J. Plante
Joseph A. Vivolo
Robert Y. Jin
Michael S. Cloud
Fredric C. Colman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/434,026 external-priority patent/US6616819B1/en
Application filed by Therasense, Inc., Charles T. Liamos, Benjamin J. Feldman, Jeffrey V. Funderburk, Rajesh Krishnan, Phillip J. Plante, Joseph A. Vivolo, Robert Y. Jin, Michael S. Cloud, Fredric C. Colman filed Critical Therasense, Inc.
Publication of CA2423837A1 publication Critical patent/CA2423837A1/en
Application granted granted Critical
Publication of CA2423837C publication Critical patent/CA2423837C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

A small volume sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector. In one embodiment, the sensor determines the concentration of the analyte by discharging an amount of charge into the sample, determining the time needed to discharge the charge, and determining the current used to electrolyze a portion of the analyte using the amount of charge and the amount of time.
CA002423837A 1999-11-04 2000-10-27 Small volume in vitro analyte sensor and methods Expired - Fee Related CA2423837C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/434,026 1999-11-04
US09/434,026 US6616819B1 (en) 1999-11-04 1999-11-04 Small volume in vitro analyte sensor and methods
CA002358993A CA2358993C (en) 1999-11-04 2000-10-27 Small volume in vitro analyte sensor and related methods

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002358993A Division CA2358993C (en) 1999-11-04 2000-10-27 Small volume in vitro analyte sensor and related methods

Publications (2)

Publication Number Publication Date
CA2423837A1 true CA2423837A1 (en) 2001-05-10
CA2423837C CA2423837C (en) 2007-09-11

Family

ID=25682753

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002423837A Expired - Fee Related CA2423837C (en) 1999-11-04 2000-10-27 Small volume in vitro analyte sensor and methods

Country Status (1)

Country Link
CA (1) CA2423837C (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006023810A1 (en) * 2004-08-20 2006-03-02 Bayer Healthcare Llc Contact connector assembly for a sensor-dispensing instrument
WO2015106331A1 (en) * 2014-01-16 2015-07-23 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Lateral flow assay apparatus and method, and sensor therefor
US9835582B2 (en) 2005-09-30 2017-12-05 Ascensia Diabetes Care Holdings Ag Devices using gated voltammetry methods
US9933385B2 (en) 2007-12-10 2018-04-03 Ascensia Diabetes Care Holdings Ag Method of using an electrochemical test sensor
US10067082B2 (en) 2004-02-06 2018-09-04 Ascensia Diabetes Care Holdings Ag Biosensor for determining an analyte concentration
US10190150B2 (en) 2006-10-24 2019-01-29 Ascensia Diabetes Care Holdings Ag Determining analyte concentration from variant concentration distribution in measurable species

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2890945C (en) 2005-07-20 2016-11-29 Bayer Healthcare Llc Gated amperometry

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10067082B2 (en) 2004-02-06 2018-09-04 Ascensia Diabetes Care Holdings Ag Biosensor for determining an analyte concentration
US7416430B2 (en) 2004-08-20 2008-08-26 Bayer Healthcare Llc Contact connector assembly for a sensor-dispensing instrument
US7575457B2 (en) 2004-08-20 2009-08-18 Bayer Healthcare Llc Contact connector assembly for a sensor-dispensing instrument
CN101040185B (en) * 2004-08-20 2012-11-14 拜尔健康护理有限责任公司 Contact connector assembly for a sensor-dispensing instrument
WO2006023810A1 (en) * 2004-08-20 2006-03-02 Bayer Healthcare Llc Contact connector assembly for a sensor-dispensing instrument
US10670553B2 (en) 2005-09-30 2020-06-02 Ascensia Diabetes Care Holdings Ag Devices using gated voltammetry methods
US9835582B2 (en) 2005-09-30 2017-12-05 Ascensia Diabetes Care Holdings Ag Devices using gated voltammetry methods
US11435312B2 (en) 2005-09-30 2022-09-06 Ascensia Diabetes Care Holdings Ag Devices using gated voltammetry methods
US10190150B2 (en) 2006-10-24 2019-01-29 Ascensia Diabetes Care Holdings Ag Determining analyte concentration from variant concentration distribution in measurable species
US11091790B2 (en) 2006-10-24 2021-08-17 Ascensia Diabetes Care Holdings Ag Determining analyte concentration from variant concentration distribution in measurable species
US9933385B2 (en) 2007-12-10 2018-04-03 Ascensia Diabetes Care Holdings Ag Method of using an electrochemical test sensor
US10690614B2 (en) 2007-12-10 2020-06-23 Ascensia Diabetes Care Holdings Ag Method of using an electrochemical test sensor
WO2015106331A1 (en) * 2014-01-16 2015-07-23 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Lateral flow assay apparatus and method, and sensor therefor

Also Published As

Publication number Publication date
CA2423837C (en) 2007-09-11

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Effective date: 20201027