CA2352520A1 - Synthese de derives de tetrahydrothieno-[3,2-c]-pyridine - Google Patents

Synthese de derives de tetrahydrothieno-[3,2-c]-pyridine Download PDF

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Publication number
CA2352520A1
CA2352520A1 CA 2352520 CA2352520A CA2352520A1 CA 2352520 A1 CA2352520 A1 CA 2352520A1 CA 2352520 CA2352520 CA 2352520 CA 2352520 A CA2352520 A CA 2352520A CA 2352520 A1 CA2352520 A1 CA 2352520A1
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CA
Canada
Prior art keywords
formula
compound
see
iii
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2352520
Other languages
English (en)
Other versions
CA2352520C (fr
Inventor
Stephen E. Horne
Jaipal Reddy Nagireddy
Laura Kaye Mcconachie
Gamini Weeratunga
Bogdan M. Comanita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Apotex Pharmachem Inc
Original Assignee
Brantford Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brantford Chemicals Inc filed Critical Brantford Chemicals Inc
Priority to CA 2352520 priority Critical patent/CA2352520C/fr
Priority to US09/902,165 priority patent/US6495691B1/en
Priority to PCT/CA2002/001017 priority patent/WO2003004502A1/fr
Priority to EP02745008A priority patent/EP1404681A1/fr
Publication of CA2352520A1 publication Critical patent/CA2352520A1/fr
Application granted granted Critical
Publication of CA2352520C publication Critical patent/CA2352520C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
CA 2352520 2001-07-06 2001-07-06 Synthese de derives de tetrahydrothieno-[3,2-c]-pyridine Expired - Fee Related CA2352520C (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA 2352520 CA2352520C (fr) 2001-07-06 2001-07-06 Synthese de derives de tetrahydrothieno-[3,2-c]-pyridine
US09/902,165 US6495691B1 (en) 2001-07-06 2001-07-11 Process for the preparation of tetrahydrothieno[3,2-c]pyridine derivatives
PCT/CA2002/001017 WO2003004502A1 (fr) 2001-07-06 2002-07-05 Procede de preparation de derives de tetrahydrothieno[3,2-c]pyridine
EP02745008A EP1404681A1 (fr) 2001-07-06 2002-07-05 Procede de preparation de derives de tetrahydrothieno 3,2-c]pyridine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2352520 CA2352520C (fr) 2001-07-06 2001-07-06 Synthese de derives de tetrahydrothieno-[3,2-c]-pyridine

Publications (2)

Publication Number Publication Date
CA2352520A1 true CA2352520A1 (fr) 2003-01-06
CA2352520C CA2352520C (fr) 2007-10-02

Family

ID=4169420

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2352520 Expired - Fee Related CA2352520C (fr) 2001-07-06 2001-07-06 Synthese de derives de tetrahydrothieno-[3,2-c]-pyridine

Country Status (3)

Country Link
EP (1) EP1404681A1 (fr)
CA (1) CA2352520C (fr)
WO (1) WO2003004502A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100678287B1 (ko) 2005-06-23 2007-02-02 한미약품 주식회사 클로피도그렐의 제조방법 및 이에 사용되는 중간체
US20070191609A1 (en) * 2006-02-13 2007-08-16 Lee Pharma Limited Process for preparation of clopidogrel bisulphate form-1
PL380849A1 (pl) * 2006-10-17 2008-04-28 Adamed Spółka Z Ograniczoną Odpowiedzialnością Krystaliczna postać racemicznego -(2-chlorofenylo)-6,7-dihydrotieno[3,2-c]pirydylo-5(4H)-octanu metylu, sposób jej wytwarzania i zastosowanie

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2424278A1 (fr) * 1978-04-24 1979-11-23 Parcor Procede de preparation de thieno(2,3-c) et thieno(3,2-c)pyridines
FR2530247B1 (fr) * 1982-07-13 1986-05-16 Sanofi Sa Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique

Also Published As

Publication number Publication date
EP1404681A1 (fr) 2004-04-07
WO2003004502A1 (fr) 2003-01-16
CA2352520C (fr) 2007-10-02

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