CA2169381A1 - Enhanced cross-linking of natural tissues - Google Patents

Enhanced cross-linking of natural tissues

Info

Publication number
CA2169381A1
CA2169381A1 CA002169381A CA2169381A CA2169381A1 CA 2169381 A1 CA2169381 A1 CA 2169381A1 CA 002169381 A CA002169381 A CA 002169381A CA 2169381 A CA2169381 A CA 2169381A CA 2169381 A1 CA2169381 A1 CA 2169381A1
Authority
CA
Canada
Prior art keywords
linking
natural tissues
enhanced cross
enhanced
cross
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002169381A
Other languages
French (fr)
Other versions
CA2169381C (en
Inventor
Thomas L. Odland
Kemal Schankereli
M. William Ii Mirsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
St Jude Medical LLC
Original Assignee
Thomas L. Odland
Kemal Schankereli
St. Jude Medical, Inc.
M. William Ii Mirsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas L. Odland, Kemal Schankereli, St. Jude Medical, Inc., M. William Ii Mirsch filed Critical Thomas L. Odland
Publication of CA2169381A1 publication Critical patent/CA2169381A1/en
Application granted granted Critical
Publication of CA2169381C publication Critical patent/CA2169381C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Materials For Medical Uses (AREA)
  • Confectionery (AREA)

Abstract

The invention concerns treating a biological tissue with a low concentration of crosslinking reagent.
CA002169381A 1994-06-15 1995-06-15 Enhanced cross-linking of natural tissues Expired - Fee Related CA2169381C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25998494A 1994-06-15 1994-06-15
US08/259,984 1994-06-15
PCT/US1995/007679 WO1995034332A1 (en) 1994-06-15 1995-06-15 Enhanced cross-linking of natural tissues

Publications (2)

Publication Number Publication Date
CA2169381A1 true CA2169381A1 (en) 1995-12-21
CA2169381C CA2169381C (en) 2002-01-29

Family

ID=22987319

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002169381A Expired - Fee Related CA2169381C (en) 1994-06-15 1995-06-15 Enhanced cross-linking of natural tissues

Country Status (9)

Country Link
EP (1) EP0713400A1 (en)
JP (1) JPH09502379A (en)
CN (1) CN1131913A (en)
AU (1) AU2863495A (en)
BR (1) BR9505496A (en)
CA (1) CA2169381C (en)
NO (1) NO960586L (en)
WO (1) WO1995034332A1 (en)
ZA (1) ZA955010B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE40570E1 (en) 1994-07-29 2008-11-11 Edwards Lifesciences Corporation Apparatuses and methods for treating biological tissue to mitigate calcification
US5931969A (en) * 1994-07-29 1999-08-03 Baxter International Inc. Methods and apparatuses for treating biological tissue to mitigate calcification
AUPN363995A0 (en) * 1995-06-19 1995-07-13 Memtec Limited Electrochemical cell
CA2326322C (en) * 1998-04-21 2011-03-01 University Of Connecticut Free-form nanofabrication using multi-photon excitation
US6214054B1 (en) 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
FR2786400B1 (en) * 1998-11-30 2002-05-10 Imedex Biomateriaux PROCESS FOR THE PREPARATION OF A COLLAGENIC MATERIAL HAVING IN VIVO CONTROLLED BIODEGRADATION SPEED AND MATERIALS OBTAINED
US20030068815A1 (en) * 1999-02-11 2003-04-10 Stone Kevin R. Sterilized xenograft tissue
AUPR217300A0 (en) * 2000-12-20 2001-01-25 Ketharanathan, Vettivetpillai Method of creating biological and biosynthetic material for implantation
US6812211B2 (en) 2002-03-19 2004-11-02 Michael Andrew Slivka Method for nonsurgical treatment of the intervertebral disc and kit therefor
US7579381B2 (en) 2005-03-25 2009-08-25 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
US8372437B2 (en) * 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
US8007992B2 (en) 2006-10-27 2011-08-30 Edwards Lifesciences Corporation Method of treating glutaraldehyde-fixed pericardial tissue with a non-aqueous mixture of glycerol and a C1-C3 alcohol
US9101691B2 (en) 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
CN101766842B (en) * 2010-03-22 2013-11-06 四川大学 Biological tissue material for artificial organs and preparation method thereof
CA2794121C (en) 2010-03-23 2016-10-11 Edwards Lifesciences Corporation Methods of conditioning sheet bioprosthetic tissue
US8906601B2 (en) 2010-06-17 2014-12-09 Edwardss Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
US9351829B2 (en) 2010-11-17 2016-05-31 Edwards Lifesciences Corporation Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability
US9358107B2 (en) 2011-06-30 2016-06-07 Edwards Lifesciences Corporation Systems, dies, and methods for processing pericardial tissue
US10238771B2 (en) 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
US10405975B2 (en) * 2015-10-07 2019-09-10 Boston Scientific Scimed, Inc. Cultured cell leaflet material
US20170173214A1 (en) * 2015-12-21 2017-06-22 Medtronic Vascular, Inc. Methods for preparing dry cross-linked tissue
WO2020092205A1 (en) 2018-11-01 2020-05-07 Edwards Lifesciences Corporation Transcatheter pulmonic regenerative valve
CN111701078B (en) * 2020-04-20 2022-08-19 上海以心医疗器械有限公司 Method for improving cross-linking degree of biological tissue

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405327A (en) * 1982-08-25 1983-09-20 Extracorporeal Medical Specialties, Inc. Method for inhibiting mineralization of natural tissue during implantation
ES8605858A1 (en) * 1984-08-14 1986-04-01 Shiley Inc Retarded mineralization of implantable tissue by surface active betaines.

Also Published As

Publication number Publication date
ZA955010B (en) 1996-02-08
CA2169381C (en) 2002-01-29
AU2863495A (en) 1996-01-05
EP0713400A1 (en) 1996-05-29
CN1131913A (en) 1996-09-25
WO1995034332A1 (en) 1995-12-21
JPH09502379A (en) 1997-03-11
NO960586L (en) 1996-03-08
BR9505496A (en) 1997-08-12
NO960586D0 (en) 1996-02-14

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Legal Events

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