CA2058785A1 - Method of producing proteins with fviii activity and/or fviii derivatives - Google Patents

Method of producing proteins with fviii activity and/or fviii derivatives

Info

Publication number
CA2058785A1
CA2058785A1 CA 2058785 CA2058785A CA2058785A1 CA 2058785 A1 CA2058785 A1 CA 2058785A1 CA 2058785 CA2058785 CA 2058785 CA 2058785 A CA2058785 A CA 2058785A CA 2058785 A1 CA2058785 A1 CA 2058785A1
Authority
CA
Canada
Prior art keywords
fviii
derivatives
producing proteins
activity
culturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2058785
Other languages
French (fr)
Other versions
CA2058785C (en
Inventor
Poul B. Rasmussen
Ole Nordfang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Priority to CA 2058785 priority Critical patent/CA2058785C/en
Publication of CA2058785A1 publication Critical patent/CA2058785A1/en
Application granted granted Critical
Publication of CA2058785C publication Critical patent/CA2058785C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Abstract

In a process for producing proteins with FVIII activity and FVIII derivatives by in vitro culturing of mammalian cells, the culturing is carried out at temperatures below 32°C and the culturing times used are below 24 hours.
CA 2058785 1992-01-06 1992-01-06 Method of producing proteins with fviii activity and/or fviii derivatives Expired - Lifetime CA2058785C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA 2058785 CA2058785C (en) 1992-01-06 1992-01-06 Method of producing proteins with fviii activity and/or fviii derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2058785 CA2058785C (en) 1992-01-06 1992-01-06 Method of producing proteins with fviii activity and/or fviii derivatives

Publications (2)

Publication Number Publication Date
CA2058785A1 true CA2058785A1 (en) 1993-07-07
CA2058785C CA2058785C (en) 1999-07-06

Family

ID=4149031

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2058785 Expired - Lifetime CA2058785C (en) 1992-01-06 1992-01-06 Method of producing proteins with fviii activity and/or fviii derivatives

Country Status (1)

Country Link
CA (1) CA2058785C (en)

Also Published As

Publication number Publication date
CA2058785C (en) 1999-07-06

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Effective date: 20120106