BRPI0600473A - polymeric implant and its preparation process - Google Patents

polymeric implant and its preparation process

Info

Publication number
BRPI0600473A
BRPI0600473A BRPI0600473-3A BRPI0600473A BRPI0600473A BR PI0600473 A BRPI0600473 A BR PI0600473A BR PI0600473 A BRPI0600473 A BR PI0600473A BR PI0600473 A BRPI0600473 A BR PI0600473A
Authority
BR
Brazil
Prior art keywords
polymeric
implant
polymeric implant
paste
preparation process
Prior art date
Application number
BRPI0600473-3A
Other languages
Portuguese (pt)
Inventor
Jefter Fernandes Nascimento
Wagner Mauricio Pachekoski
Original Assignee
Phb Ind Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phb Ind Sa filed Critical Phb Ind Sa
Priority to BRPI0600473-3A priority Critical patent/BRPI0600473A/en
Priority to CN2007800046130A priority patent/CN101378733B/en
Priority to EP07701612A priority patent/EP1981486A2/en
Priority to DO2007P000026A priority patent/DOP2007000026A/en
Priority to US12/161,613 priority patent/US20090291119A1/en
Priority to PCT/BR2007/000028 priority patent/WO2007090255A2/en
Priority to KR1020087021137A priority patent/KR20080094805A/en
Priority to JP2008552652A priority patent/JP2009526093A/en
Priority to CA002641043A priority patent/CA2641043A1/en
Priority to AU2007214274A priority patent/AU2007214274A1/en
Publication of BRPI0600473A publication Critical patent/BRPI0600473A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Steroid Compounds (AREA)
  • Materials For Medical Uses (AREA)

Abstract

IMPLANTE POLIMéRICO E SEU PROCESSO DE PREPARAçãO. Implante polimérico, obtido a partir de uma fonte renovável, compreendendo um corpo formado por pelo menos um polímero biodegradável selecionado do grupo consistindo de Polihidroxialcanoatos (PHAs) e de seus copolímeros, dito corpo incorporando, em sua micro-estrutura, um ingrediente ativo em quantidade suficiente para controlar pelo menos um ciclo estral de animais mamíferos. A invenção refere-se ainda a um processo para preparação do implante polimérico, que compreende as etapas de: misturar progesterona ou progestágenos; pelo menos um polímero do grupo de PHAs, um aditivo polimérico definido por poli (<sym>-caprolactona), e pelo menos um aditivo dispersante e ou solvente, para obter uma solução coloidal; evaporar o solvente da solução coloidal, e formar uma pasta com os componentes nela dispersos; secar a pasta para remoção dos solventes residuais e controle da granulometria do compósito polimérico; extrudar o compósito polimérico e moldá-lo em um corpo de implante.POLYMERIC IMPLANT AND THEIR PREPARATION PROCESS. Polymeric implant, obtained from a renewable source, comprising a body formed by at least one biodegradable polymer selected from the group consisting of Polyhydroxyalkanoates (PHAs) and their copolymers, said body incorporating, in its microstructure, a quantity active ingredient sufficient to control at least one estrous cycle of mammalian animals. The invention further relates to a process for preparing the polymeric implant comprising the steps of: mixing progesterone or progestins; at least one PHA group polymer, a poly (<sym> -caprolactone) defined polymeric additive, and at least one dispersant and or solvent additive to obtain a colloidal solution; evaporating the solvent from the colloidal solution, and forming a paste with the components dispersed therein; drying the paste to remove residual solvents and control the particle size of the polymer composite; extrude the polymeric composite and mold it into an implant body.

BRPI0600473-3A 2006-02-06 2006-02-06 polymeric implant and its preparation process BRPI0600473A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
BRPI0600473-3A BRPI0600473A (en) 2006-02-06 2006-02-06 polymeric implant and its preparation process
CN2007800046130A CN101378733B (en) 2006-02-06 2007-02-06 Polymeric implant and a process for obtaining a polymeric implant
EP07701612A EP1981486A2 (en) 2006-02-06 2007-02-06 Polymeric implant and a process for obtaining a polymeric implant
DO2007P000026A DOP2007000026A (en) 2006-02-06 2007-02-06 POLYMERIC IMPLANT AND A PROCESS TO OBTAIN A POLYMERIC IMPLANT.
US12/161,613 US20090291119A1 (en) 2006-02-06 2007-02-06 Polymeric implant and a process for obtaining a polymeric implant
PCT/BR2007/000028 WO2007090255A2 (en) 2006-02-06 2007-02-06 Polymeric implant and a process for obtaining a polymeric implant
KR1020087021137A KR20080094805A (en) 2006-02-06 2007-02-06 Polymeric implant and a process for obtaining a polymeric implant
JP2008552652A JP2009526093A (en) 2006-02-06 2007-02-06 Polymer implants and methods for obtaining polymer implants
CA002641043A CA2641043A1 (en) 2006-02-06 2007-02-06 Polymeric implant and a process for obtaining a polymeric implant
AU2007214274A AU2007214274A1 (en) 2006-02-06 2007-02-06 Polymeric implant and a process for obtaining a polymeric implant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0600473-3A BRPI0600473A (en) 2006-02-06 2006-02-06 polymeric implant and its preparation process

Publications (1)

Publication Number Publication Date
BRPI0600473A true BRPI0600473A (en) 2007-10-23

Family

ID=37903568

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0600473-3A BRPI0600473A (en) 2006-02-06 2006-02-06 polymeric implant and its preparation process

Country Status (10)

Country Link
US (1) US20090291119A1 (en)
EP (1) EP1981486A2 (en)
JP (1) JP2009526093A (en)
KR (1) KR20080094805A (en)
CN (1) CN101378733B (en)
AU (1) AU2007214274A1 (en)
BR (1) BRPI0600473A (en)
CA (1) CA2641043A1 (en)
DO (1) DOP2007000026A (en)
WO (1) WO2007090255A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0600681A (en) * 2006-02-24 2007-11-20 Phb Ind Sa environmentally degradable polymeric blend and its process of obtaining
CA2886522A1 (en) * 2015-03-30 2016-09-30 Precise.Ai Inc. Intravaginal sensor and methods for selecting an insemination time
AR105311A1 (en) * 2015-07-23 2017-09-27 Biogénesis Bagó S A USE OF INTRAVAGINAL DEVICE TO INCREASE THE INCREASE IN WEIGHT AND IMPROVE THE QUALITY OF THE HOUSING IN BOVINE FEMALES, METHOD FOR SUPPRESSING THE ESTRO IN FEMALE ANIMALS
AU201617347S (en) * 2016-12-23 2017-01-23 Jurox Pty Ltd intravaginal device

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4129536A (en) * 1977-07-25 1978-12-12 Rca Corporation Vinyl chloride based injection molding composition
EP0696185B1 (en) * 1993-04-28 1998-08-12 Focal, Inc. Apparatus, product and use related to intraluminal photothermoforming
NZ330596A (en) * 1998-06-05 2001-02-23 Dec Res Intravaginal devices allowing for increased uptake of active ingredients
MXPA05003829A (en) * 2002-10-11 2005-10-05 Novocell Inc Implantation of encapsulated biological materials for treating diseases.
JP4792690B2 (en) * 2003-06-10 2011-10-12 東レ株式会社 Resin composition and molded article comprising the same

Also Published As

Publication number Publication date
WO2007090255A2 (en) 2007-08-16
US20090291119A1 (en) 2009-11-26
CN101378733B (en) 2013-03-06
EP1981486A2 (en) 2008-10-22
AU2007214274A1 (en) 2007-08-16
WO2007090255A3 (en) 2007-11-29
CA2641043A1 (en) 2007-08-16
CN101378733A (en) 2009-03-04
JP2009526093A (en) 2009-07-16
KR20080094805A (en) 2008-10-24
DOP2007000026A (en) 2007-08-31

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2448 DE 05-12-2017 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.