BRPI0512104A8 - preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and their derivatives - Google Patents
preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and their derivativesInfo
- Publication number
- BRPI0512104A8 BRPI0512104A8 BRPI0512104A BRPI0512104A BRPI0512104A8 BR PI0512104 A8 BRPI0512104 A8 BR PI0512104A8 BR PI0512104 A BRPI0512104 A BR PI0512104A BR PI0512104 A BRPI0512104 A BR PI0512104A BR PI0512104 A8 BRPI0512104 A8 BR PI0512104A8
- Authority
- BR
- Brazil
- Prior art keywords
- deoxy
- fluoro
- derivatives
- alkyl
- preparation
- Prior art date
Links
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- Saccharide Compounds (AREA)
Abstract
preparação de 2-desóxi-2-flúor-d-ribofuranosil pirimidinas substituídas com alquila e purinas e seus derivados a presente invenção provê (i) um processo para preparação de um derivado de 2-desóxi-2-flúor-2-metil-d-ribonolactona, (ii) conversão da lactona nos nucleosídeos com atividade anti-hcv potente e seus análogos e (iii) método para preparar os nucleosídeos anti-hcv contendo os nucleosídeos 2-desóxi-2-flúor-2-c-metil--ß-d-ribofuranosila a partir de um nucleosídeo pré-formado, preferivelmente ocorrendo naturalmente.Preparation of Alkyl-Purified Substituted 2-Deoxy-2-Fluoro-d-Ribofuranosyl Pyrimidines and derivatives thereof The present invention provides (i) a process for preparing a 2-Deoxy-2-fluoro-2-methyl-d derivative (ii) conversion of lactone to potent anti-hcv activity nucleosides and their analogues and (iii) method for preparing anti-hcv nucleosides containing 2-deoxy-2-fluoro-2-c-methyl nucleosides-- ß-d-ribofuranosyl from a preformed nucleoside, preferably occurring naturally.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58986604P | 2004-07-21 | 2004-07-21 | |
US60832004P | 2004-09-09 | 2004-09-09 | |
PCT/US2005/025916 WO2006012440A2 (en) | 2004-07-21 | 2005-07-21 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and purines and their derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0512104A BRPI0512104A (en) | 2008-03-11 |
BRPI0512104A8 true BRPI0512104A8 (en) | 2018-04-24 |
Family
ID=39153774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0512104A BRPI0512104A8 (en) | 2004-07-21 | 2005-07-21 | preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and their derivatives |
Country Status (1)
Country | Link |
---|---|
BR (1) | BRPI0512104A8 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3521297B1 (en) | 2003-05-30 | 2021-12-22 | Gilead Pharmasset LLC | Modified fluorinated nucleoside analogues |
-
2005
- 2005-07-21 BR BRPI0512104A patent/BRPI0512104A8/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BRPI0512104A (en) | 2008-03-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: GILEAD PHARMASSET LLC (US) |
|
B25G | Requested change of headquarter approved |
Owner name: GILEAD PHARMASSET LLC (US) |
|
B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law | ||
B07E | Notice of approval relating to section 229 industrial property law |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B07A | Technical examination (opinion): publication of technical examination (opinion) | ||
B09B | Decision: refusal | ||
B09B | Decision: refusal |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |