BR112020000465B1 - OXADIAZOLE DERIVATIVES MICROBIOCIDES - Google Patents

Abstract

compounds of formula (i): (i) wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.

Description

[0001] The present invention relates to microbicidal oxadiazole derivatives, for example, as active ingredients, which have microbicidal activity, in particular, fungicidal activity. The invention also relates to agrochemical compositions comprising at least one of the oxadiazole derivatives, to processes for preparing these compounds and to uses of the oxadiazole derivatives or compositions in agriculture or horticulture for controlling or preventing infestation of plants, harvested food crops, seeds or non-living materials by phytopathogenic microorganisms, preferably fungi.

[0002] According to the present invention, a compound of formula (I) is provided: wherein R1, R2, R3, R4 are independently selected from hydrogen or fluorine and wherein 0, 1 or 2 of R1, R2, R3 and R4 are fluorine; R5 and R6 are independently selected from hydrogen or C1-4alkyl; and Z represents Z1 or Z2: where R7 represents: (i) -C(O)N(Ra)(Rb), where: Ra is hydrogen, C1-5alkyl, C3-6cycloalkyl, C1- 4haloalkyl, C3-5alkenyl, C3-4alkynyl, C1- 4alkoxy, C1- 2alkoxyC1-2alkyl, C3-5alkenyloxy, C3-6cycloalkyl-C1- 4alkoxy, C1-4haloalkoxy, C3-4alkynyloxy, benzyl, furylmethyl, morpholin-4-yl, piperidin-1-yl, N,N-diC1- 4alkylamino, phenyl, C3-6cycloalkyl-C1-4alkyl, C3-6halocycloalkyl-C1-4alkyl, formyl(methyl)amino, isoxazolidin-2-yl, 5-azaspiro[2.4]heptan-5-yl; and Rb is hydrogen, C1-5alkyl, C3-6cycloalkyl, C3-5alkenyl, C3-4alkynyl; or Ra and Rb, together with the nitrogen atom to which they are attached, form a 4-, 5- or 6-membered cycle optionally containing an additional heteroatom or group selected from O, S, S(O)2, C(O) and NRc, where Rc is hydrogen, methyl, methoxy, formyl or acyl; or (ii) -C(O)ORd, where: Rd is hydrogen, C1-5alkyl, C1-4haloalkyl, tetrahydrofuranyl, oxetanyl, C3-6cycloalkyl, C3-5alkenyl, C1-4alkoxyC1-4alkyl, phenyl, benzyl, C3-6cycloalkylC1-4alkyl, C3-4alkynyl; or a salt or an N-oxide thereof.

[0003] Surprisingly it was discovered that the new compounds of Formula (I) have, for practical purposes, a very advantageous level of biological activity to protect plants against diseases that are caused by fungi.

[0004] According to a second aspect of the invention there is provided an agrochemical composition comprising a fungicidal effective amount of a compound of Formula (I). Such an agricultural composition may further comprise at least one additional active ingredient and/or an agrochemically acceptable diluent or carrier.

[0005] According to a third aspect of the invention there is provided a method for controlling or preventing infestation of useful plants by phytopathogenic microorganisms, in which a fungicidal effective amount of a compound of Formula (I), or a composition comprising this compound as an active ingredient, it is applied to plants, their parts or their locus.

[0006] According to a fourth aspect of the invention, the use of a compound of Formula (I) as a fungicide is provided. According to this particular aspect of the invention, use may exclude methods for treating the human or animal body by surgery or therapy.

[0007] As used herein, the term "halogen" or "halo" refers to fluorine (fluorine), chlorine (chlorine), bromine (bromine) or iodine (iodine), preferably fluorine, chlorine or bromine.

[0008] As used here, acyl means a -C(O)CH3 group.

[0009] As used here, formyl means a group - C(O)H.

[0010] As used herein, the term “C1-5alkyl” refers to a straight or branched hydrocarbon chain radical consisting only of carbon and hydrogen atoms, containing no unsaturation, having from one to five carbon atoms and which is linked to the rest of the molecule by a single bond. C1-4alkyl, C1-3alkyl and C1-2alkyl should be considered accordingly. Examples of C1-5alkyl include, but are not limited to, methyl, ethyl, n-propyl, 1-methylethyl (isopropyl), n-butyl and 1-dimethylethyl (t-butyl). A "C1-C4alkylene" group refers to the corresponding definition of C1-C4alkyl, with the exception that such radical is linked to the remainder of the molecule by two single bonds. Examples of C1-4alkylene are -CH2- and -CH2CH2-.

[0011] As used herein, the term "C1-4alkoxy" refers to a radical of the formula -ORa in which Ra is a C1-4alkyl radical as generically defined above. The terms C1-3alkoxy and C1-2alkoxy must be interpreted accordingly. Examples of C1-4alkoxy include, but are not limited to, methoxy, ethoxy, propoxy, isopropoxy and t-butoxy.

[0012] As used herein, the term "C1-4haloalkyl" refers to a C1-3alkyl radical as generally defined above substituted with one or more same or different halogen atoms. Examples of C1-4haloalkyl include, but are not limited to, fluoromethyl, fluoroethyl, difluoromethyl, trifluoromethyl, 2,2,2-trifluoroethyl and 3,3,3-trifluoropropyl.

[0013] As used herein, the term "C3-5 alkenyl" refers to a linear or branched hydrocarbon chain radical group consisting merely of carbon and hydrogen atoms, containing at least one double bond that may have the (E) configuration or (Z), having three to five carbon atoms, which is linked to the remainder of the molecule by a single bond. Examples of C3-5alkenyl include, but are not limited to, prop-1-enyl, allyl (prop-2 -enyl) and but-1- enyl.

[0014] As used herein, the term “C3-5alkenoxy” refers to a radical of the formula -ORa in which Ra is a C3-5alkenyl radical as generally defined above.

[0015] As used herein, the term “C3-4alkynyl” refers to a linear or branched hydrocarbon chain radical group consisting only of carbon and hydrogen atoms, containing at least one triple bond, having three or four carbon atoms and which is linked to the rest of the molecule by a single bond. Examples of C2-6alkynyl include, but are not limited to, prop-1-ynyl, propargyl (prop-2-ynyl).

[0016] As used here, the term “C3-4alkynoxy” refers to a radical of the formula -ORa in which Ra is a C3-4alkynyl radical as generically defined above.

[0017] As used herein, the term “C1-4alkoxyC1-4alkyl” refers to a radical of the formula Rb-O-Ra- wherein Rb is a C1-4alkyl radical as generally defined above, and Ra is a C1- radical. 4alkylene as generally defined above.

[0018] As used herein, the term “C3-6cycloalkyl” refers to a stable monocyclic ring radical that is saturated or partially unsaturated and contains 3 to 6 carbon atoms. C3-5Cycloalkyl and C3cycloalkyl should be interpreted accordingly. Examples of C3-6cycloalkyl include, but are not limited to, cyclopropyl, cyclobutyl, cyclopentyl, cyclopenten-1-yl, cyclopenten-3-yl and cyclohexen-3-yl.

[0019] As used here, the term “C3-6cycloalkylC1-4alkyl” refers to a C3-6cycloalkyl ring as defined above linked to the remainder of the molecule by a C1-4alkylene radical as defined above. Examples of C3-6cycloalkylC1-3alkyl include, but are not limited to, cyclopropyl-methyl and cyclobutyl-ethyl.

[0020] The presence of one or more possible asymmetric carbon atoms in a compound of Formula (I) means that the compounds can occur in chiral isomeric forms, that is, enantiomeric or diastereomeric forms. Atropisomers can also occur as a result of restricted rotation around a single bond. Formula (I) is intended to include all such possible isomeric forms and mixtures thereof. The present invention includes all such possible isomeric forms and mixtures thereof for a compound of Formula (I). Likewise, Formula (I) is intended to include all possible tautomers (including lactam-lactime tautomerism and keto-enol tautomerism) when present. The present invention includes all possible tautomeric forms for a compound of Formula (I).

[0021] In each case, the compounds of Formula (I) according to the invention are in free form, in oxidized form as an N-oxide, in covalently hydrated form or in salt form, e.g. agronomically usable or agrochemically acceptable.

[0022] N-oxides are oxidized forms of tertiary amines or oxidized forms of heteroaromatic compounds that contain nitrogen. They are described, for example, in the book “Heterocyclic N-oxides” by A. Albini and S. Pietra, CRC Press, Boca Raton 1991.

[0023] The following list provides definitions, including preferred definitions, for the substituents R1, R2, R3, R4, R5, R6, Z (including Z1 and Z2) and R7 (including Ra, Rb, Rc and Rd) with reference to the compounds of Formula (I) according to the invention. For any of these substituents, any of the definitions presented below may be combined with any definition of any other substituent presented below or elsewhere in this document.

[0024] R1, R2, R3, R4 are independently selected from hydrogen or fluorine, wherein 0, 1 or 2 of R1, R2, R3 and R4 are fluorine.

[0025] In certain embodiments of the invention, R1, R2, R3 and R4 are hydrogen; R2, R3 and R4 are hydrogen and R1 is fluorine; R1, R2 and R4 are hydrogen and R3 is fluorine; R1 and R2 are fluorine and R3 and R4 are hydrogen; R1 and R3 are fluorine and R2 and R4 are hydrogen, or R1 and R2 are hydrogen and R3 and R4 are fluorine. Preferably, R1 to R4 are hydrogen.

[0026] R5 and R6 independently represent hydrogen or C1-4alkyl (such as methyl). Preferably, R5 and R6 are both hydrogen, or R5 is hydrogen and R6 is methyl. More preferably, R5 and R6 are both hydrogen. Z represents Z1 or Z2: In some embodiments of the invention, Z is Z1. In some embodiments of the invention, Z is Z2. R7 can represent -C(O)N(Ra)(Rb), where: Ra is hydrogen, C1-5alkyl, C3-6cycloalkyl, C1- 4haloalkyl, C3-5alkenyl, C3-4alkynyl, C1-4alkoxy, C1- 2alkoxyC1 -2alkyl, C3-5alkenyloxy, C3-6cycloalkyl-C1- 4alkoxy, C1-4haloalkoxy, C3-4alkynyloxy, benzyl, furylmethyl, morpholin-4-yl, piperidin-1-yl, N,N-diC1- 4alkylamino, phenyl, C3 -6cycloalkyl-C1-4alkyl, C3-6halocycloalkyl-C1-4alkyl, N-formyl-N-(methyl)amino, isoxazolidin-2-yl, 5-azaspiro[2.4]heptan-5-yl; and Rb is hydrogen, C1-5alkyl, C3-6cycloalkyl, C3-5alkenyl, C3-4alkynyl; or Ra and Rb, together with the nitrogen atom to which they are attached, form a 4-, 5- or 6-membered cycle optionally containing an additional heteroatom or group selected from O, S, S(O)2, C(O) and NRc, where Rc is hydrogen, methyl, methoxy, formyl or acyl.

[0027] Preferably, Ra is hydrogen, C1-4alkyl, C3-6cycloalkyl, C1-2fluoroalkyl, C3-4alkenyl, C3-4alkynyl, C1-4alkoxy, C1-2alkoxyC1-2alkyl, C3-4alkenyloxy, C3-6cycloalkylC1-2alkoxy, C1 -2fluoroalkoxy, C3-4alkynyloxy, benzyl, furylmethyl (including furan-2-ylmethyl and furan-3-ylmethyl), morpholin-4-yl, piperidin-1-yl, N,N-diC1-4alkylamino, phenyl, C3-6cycloalkylC1 -2alkyl, C3-6fluorocycloalkyl, C1-2alkyl, N-formyl-N-(methyl)amino, isoxazolidin-2-yl, 5-azaspiro[2.4]heptan-5-yl. More preferably, Ra is hydrogen, C1-4alkyl, C1-2fluoroalkyl, C1-2alkoxyC1-2alkyl, C3-4alkenyl or C3-4alkynyl. Even more preferably, Ra is hydrogen or C1-4alkyl.

[0028] Preferably, Rb is hydrogen, C1-5alkyl or cyclopropyl, and more preferably Rb is hydrogen or cyclopropyl.

[0029] R7 can represent -C(O)ORd, where Rd is hydrogen, C1-5alkyl, C1-4haloalkyl, tetrahydrofuranyl (including tetrahydrofuran-2-yl and tetrahydrofuran-3-yl), oxetanyl (including oxetan-2-yl and oxetan-3-yl), C3-6cycloalkyl, C3-5alkenyl, C1-4alkoxyC1-4alkyl, phenyl, benzyl, C3-6cycloalkylC1-4alkyl, C3-4alkynyl.

[0030] Preferably, Rd is C1-5alkyl, C1-4fluoroalkyl, tetrahydrofuranyl, oxetanyl, C3-6cycloalkyl, C3-5alkenyl, C1-2alkoxyC1-2alkyl, phenyl, benzyl, C3-6cycloalkylC1-2alkyl, C3-4alkynyl.

[0031] Preferably, the compound according to Formula (I) is selected from compound A.1 to A.43 described in Table A (below) or compound B.1 to B.24 described in Table B (below).

[0032] The compounds of the present invention may be enantiomers of the compound of Formula (I) as represented by a Formula (Ia) or a Formula (Ib), wherein R5 and R6 are different substituents.

[0033] compounds of formula (I) according to the invention may be present in a reversible equilibrium with the corresponding covalently hydrated forms (i.e., the compounds of formula (I-Ia) and formula (I-IIa) as shown below , which can exist in tautomeric form as the compounds of formula (I-Ib) and formula (I-IIb)) in the CF3-oxadiazole motif). This dynamic balance may be important for the biological activity of the compounds of Formula (I). The designations R1, R2, R3, R4, R5, R6, Z (including Z1 and Z2) and R7 (including Ra, Rb, Rc and Rd) with reference to the compounds of formula (I) of the present invention apply generally to the compounds of Formula (I-Ia), Formula (I-IIa), Formula (I-Ib), and Formula (I-IIb), as well as specific disclosures of combinations of R1, R2, R3, R4, R5, R6, Z (including Z1 and Z2) and R7 (including Ra, Rb, Rc and Rd) represented by compounds T-2.01 through T-2.14 through T-66.01 through T-66.14 shown in Tables 2 through 66 (below) and compounds A. 1 to A.43 described in Table A (below) or compounds B.1 to B.24 described in Table B (below).

[0034] The compounds of the present invention can be prepared as shown in the following schemes 1 to 11, in which, unless otherwise stated, the definition of each variable is as defined above for a compound of formula (I).

[0035] Compounds of formula (I) can be prepared from compounds of formula (II), where X is a halogen, preferably Cl, Br or I, by treatment with compounds of formula (III), in the presence of a base (e.g. K2CO3, Cs2CO3 or NaH) in a suitable solvent (e.g. dimethylformamide or tetrahydrofuran) at a temperature between 25 °C and 110 °C. In some cases, better reaction performance can be gained with the use of a catalyst (e.g., NaI or 4-dimethylaminopyridine) and with microwave irradiation. For related examples see: WO 2013/132253 and Garcia, M. et al. Org. Biomol. Chem. (2004), 11, 1633. This reaction is shown in Scheme 1.

[0036] Additionally, compounds of formula (I), where preferably n is 1, can be prepared from compounds of formula (IV) by treatment with trifluoroacetic anhydride in the presence of a base (for example, pyridine or 4- dimethylaminopyridine) in a suitable solvent, such as tetrahydrofuran or ethanol, at a temperature between 25 °C and 75 °C. For related examples see WO 2003/028729 and WO 2010/045251. This reaction is shown in Scheme 2.

[0037] Compounds of formula (IV) can be prepared from compounds of formula (V) by treatment with a hydroxylamine hydrochloride salt in the presence of a base, such as triethylamine, in a suitable solvent, such as methanol, at a temperature between 0 °C and 100 °C. For related examples, see Kitamura, S. et al. Chem. Pharm. Bull. (2001), 49, 268 and WO 2013/066838. This reaction is shown in Scheme 3.

[0038] Compounds of formula (V) can be prepared from compounds of formula (VI), where Y is Br or I, through metal-promoted reaction with a suitable cyanide reagent, such as Pd(0) /Zn(CN)2 or CuCN, in a suitable solvent (for example, dimethylformamide or Nmethylpyrrolidone) at an elevated temperature between 100 °C and 120 °C. For related examples see US 2007/0155739 and WO 2009/022746. This reaction is shown in Scheme 4.

[0039] Compounds of formula (VI), where preferably n is 1, can be prepared from compounds of formula (VII), where X is a halogen, preferably Cl, Br or I, through treatment with compounds of formula (III), in the presence of a base (e.g. K2CO3, Cs2CO3 or NaH) in a suitable solvent (e.g. dimethylformamide or tetrahydrofuran) at a temperature between 25 °C and 110 °C. In some cases, better reaction performance can be obtained with the use of a catalyst (e.g., NaI or 4-dimethylaminopyridine) and with microwave irradiation. For related examples see: WO 2013/132253 and Garcia, M. et al. Org. Biomol. Chem. (2004), 11, 1633. This reaction is shown in Scheme 5.

[0040] Compounds of formula (II), where X is Cl or Br, can be prepared from compounds of formula (VIII), by treatment with a halogen source (for example, N-bromosuccimide (NBS) or N-chlorosuccinimide (NCS)) and a radical initiator (e.g. (PhCO2)2 or azobisisobutyronitrile (AIBN)) in a suitable solvent, such as tetrachloromethane, at temperatures between 55° and 100°C in the presence of ultraviolet light. For related examples, see Liu, S. et al Synthesis (2001), 14, 2078 and Kompella, A. et al Org. Proc. Res. Dev. (2012), 16, 1794. This reaction is shown in Scheme 6.

[0041] Alternatively, compounds of formula (II) can be prepared from compounds of formula (IX) by treatment with trifluoroacetic anhydride in the presence of a base (e.g., pyridine or 4-dimethylaminopyridine) in a suitable solvent, such such as tetrahydrofuran or ethanol, at a temperature between 25 °C and 75 °C. For related examples see WO 2003/028729 and WO 2010/045251. This reaction is shown in Scheme 7. Scheme 7

[0042] Compounds of formula (IX) can be prepared from compounds of formula (X) by treatment with a hydroxylamine hydrochloride salt in the presence of a base, such as triethylamine, in a suitable solvent, such as methanol, at a temperature between 0 °C and 100 °C. For related examples, see Kitamura, S. et al. Chem. Pharm. Bull. (2001), 49, 268 and WO 2013/066838. This reaction is shown in Scheme 8.

[0043] Compounds of formula (VII), where Y is Br, I or CN and X is Cl, Br or I, are commercially available or can be prepared from compounds of formula (XI), by treatment with a halogen source (e.g. N-bromosuccinimide (NBS) or N-chlorosuccinimide (NCS)) and a radical initiator, such as (PhCO2)2 or azobisisobutyronitrile (AIBN), in the presence of ultraviolet light, in a suitable solvent, such as tetrachloromethane, at temperatures between 55 °C and 100 °C. For related examples see Liu, S. et al. Synthesis (2001), 14, 2078 and Kompella, A. et al. Org. Proc. Res. Dev. (2012), 16, 1794. This reaction is shown in Scheme 9.

[0044] Alternatively, compounds of formula (VII), where X is Cl, Br, I or OSO2Me and Y is Br, I or CN, are commercially available or can be prepared from compounds of formula (XII), by treatment with a halogen source (e.g. CCl3Br, CCl4 or I2) in the presence of triphenylphosphine, or with methanesulfonyl chloride (ClSO2Me), in a suitable solvent (e.g. dichloromethane) at a temperature between 0°C and 100° W. For related examples, see Liu, H. et al Bioorg. Med. Chem. (2008), 16, 10013, WO 2014/020350 and Kompella, A. et al Bioorg. Med. Chem. Lett. (2001), 1, 3161. Compounds of formula (XII) are commercially available. This reaction is shown in Scheme 10.

[0045] The compounds of formula (Ib), in which R1, R2, R3, R4, R5 and R6 have the same meaning defined above for formula (I), can be obtained by an amide or ester coupling transformation with compounds of formula (Ia) and nucleophiles of formula (XIII), where Rx-Nu-H represents HORd or HN(Ra)Rb, by activation of the carboxylic acid function of compounds of formula (Ia), a process that usually takes place by converting the -OH of the carboxylic acid into a good leaving group, such as a chloride group, for example, using (COCl)2 or SOCl2, before treatment with the nucleophiles of formula (XIII), preferably in a suitable solvent (e.g. example, dimethylformamide, dichloromethane or tetrahydrofuran), preferably at a temperature between 25 °C and 100 °C, and optionally in the presence of a base such as triethylamine or N,N-diisopropylethylamine, or under conditions described in the literature for an amide or ester coupling. For examples, see WO 2003/028729. Compounds of formula (XIII) are commercially available or prepared using known methods. For related examples see: Nelson, T. D et al. Tetrahedron Lett. (2004), 45, 8917; Senthil, K. et al. Pest. Journal Res (2009), 21, 133; and Crich, D., Zou, YJ Org. Chem. (2005), 70, 3309. This reaction is shown in Scheme 11.

[0046] As already indicated, it has now surprisingly been discovered that the compounds of Formula (I) of the present invention have, for practical purposes, a very advantageous level of biological activity for protecting plants against diseases that are caused by fungi.

[0047] The compounds of Formula (I) can be used in the agricultural sector and related areas of use, for example, as active ingredients for controlling plant pests or in non-living materials for the control of microorganisms that cause spoilage or potentially harmful organisms. harmful to humans. The new compounds are distinguished by excellent activity at low application rates, by being well tolerated by plants and by being safe from an environmental point of view. They have very useful curative, preventive and systemic properties and can be used to protect numerous cultivated plants. The compounds of Formula (I) can be used to inhibit or destroy pests occurring on plants or plant parts (fruit, flowers, leaves, stems, tubers, roots) of different useful plant crops, while protecting, for example, from phytopathogenic microorganisms, also those parts of plants that grow later.

[0048] The present invention further relates to a method for controlling or preventing infestation of plants or plant propagation material and/or harvested food crops susceptible to microbial attack by treating the plants or plant propagation material and/or food crops harvested, in which an effective amount of a compound of Formula (I) is applied to the plants, their parts or their locus.

[0049] It is also possible to use compounds of Formula (I) as a fungicide. The term “fungicide”, as used herein, means a compound that controls, modifies or prevents the growth of fungi. The term "fungicide-effective amount", when used, means the amount of such a compound or combination of such compounds that can produce an effect on the growth of fungi. Controlling or modifying effects include all deviations from natural development, such as death, retardation and the like, and prevention includes barrier or other defensive formation in or on a plant to prevent fungal infection.

[0050] It may also be possible to use compounds of Formula (I) as covering agents for the treatment of plant propagation material, for example, seed, such as fruits, tubers or grains, or plant cuttings, for protection against fungal infections as well as against phytopathogenic fungi occurring in the soil. The propagation material can be treated with a composition comprising a compound of Formula (I) before planting: seed, for example, can be covered before being sown. The active compounds of Formula (I) can also be applied to grains (coating), by impregnating the seeds in a liquid formulation or by coating them with a solid formulation. The composition can also be applied to the planting site when the propagation material is being planted, for example in the seed furrow during sowing. The invention also relates to such methods of treating plant propagation material and the plant propagation material thus treated.

[0051] Furthermore, the compounds of Formula (I) can be used to control fungi in related areas, for example in the protection of technical materials, including wood and wood-related technical products, in food storage, in hygiene management.

[0052] Additionally, the invention can be used to protect non-living materials from fungal attack, for example, construction wood, wall panels and paint.

[0053] The compounds of Formula (I) are, for example, effective against fungi and fungal disease vectors as well as phytopathogenic bacteria and viruses. These fungi and fungal disease vectors as well as phytopathogenic bacteria and viruses are, for example: Absidia corymbifera, Alternaria spp, Aphanomyces spp, Ascochyta spp, Aspergillus spp. including A. flavus, A. fumigatus, A. nidulans, A. niger, A. terrus, Aureobasidium spp. including A. pullulans, Blastomyces dermatitidis, Blumeria graminis, Bremia lactucae, Botryosphaeria spp. including B. dothidea, B. obtusa, Botrytis spp. including B. cinerea, Candida spp. including C. albicans, C. glabrata, C. krusei, C. lusitaniae, C. parapsilosis, C. tropicalis, Cephaloascus fragrans, Ceratocystis spp, Cercospora spp. including C. arachidicola, Cercosporidium personatum, Cladosporium spp, Claviceps purpurea, Coccidioides immitis, Cochliobolus spp, Colletotrichum spp. including C. musae, Cryptococcus neoformans, Diaporthe spp, Didymella spp, Drechslera spp, Elsinoe spp, Epidermophyton spp, Erwinia amylovora, Erysiphe spp. including E. cichoracearum, Eutypa lata, Fusarium spp. including F. culmorum, F. graminearum, F. langsethiae, F. moniliforme, F. oxysporum, F. proliferatum, F. subglutinans, F. solani, Gaeumannomyces graminis, Gibberella fujikuroi, Gloeodes pomigena, Gloeosporium musarum, Glomerella cingulate, Guignardia bidwellii , Gymnosporangium juniperi-virginianae, Helminthosporium spp, Hemileia spp, Histoplasma spp. including H. capsulatum, Laetisaria fuciformis, Leptographium lindbergi, Leveillula taurica, Lophodermium seditiosum, Microdochium nivale, Microsporum spp, Monilinia spp, Mucor spp, Mycosphaerella spp. including M. graminicola, M. pomi, Oncobasidium theobromaeon, Ophiostoma piceae, Paracoccidioides spp, Penicillium spp. including P. digitatum, P. italicum, Petriellidium spp, Peronosclerospora spp. Including P. maydis, P. philippinensis and P. sorghi, Peronospora spp, Phaeosphaeria nodorum, Phakopsora pachyrhizi, Phellinus igniarus, Phialophora spp, Phoma spp, Phomopsis viticola, Phytophthora spp. including P. infestans, Plasmopara spp. including P. halstedii, P. viticola, Pleospora spp., Podosphaera spp. including P. leucotricha, Polymyxa graminis, Polymyxa betae, Pseudocercosporella herpotrichoides, Pseudomonas spp, Pseudoperonospora spp. including P. cubensis, P. humuli, Pseudopeziza tracheiphila, Puccinia Spp. including P. hordei, P. recondita, P. striiformis, P. triticina, Pyrenopeziza spp, Pyrenophora spp, Pyricularia spp. including P. oryzae, Pythium spp. including P. ultimum, Ramularia spp, Rhizoctonia spp, Rhizomucor pusillus, Rhizopus arrhizus, Rhynchosporium spp, Scedosporium spp. including S. apiospermum and S. prolificans, Schizothyrium pomi, Sclerotinia spp, Sclerotium spp, Septoria spp, including S. nodorum, S. tritici, Sphaerotheca macularis, Sphaerotheca fusca (Sphaerotheca fuliginea), Sporothorix spp, Stagonospora nodorum, Stemphylium spp,. Stereum hirsutum, Thanatephorus cucumeris, Thielaviopsis basicola, Tilletia spp, Trichoderma spp. including T. harzianum, T. pseudokoningii, T. viride, Trichophyton spp, Typhula spp, Uncinula necator, Urocystis spp, Ustilago spp, Venturia spp. including V. inaequalis, Verticillium spp, and Xanthomonas spp.

[0054] The compounds of Formula (I) can be used, for example, on grass, ornamental plants, such as flowers, shrubs, broadleaf or evergreen trees, for example, conifers, as well as for injection into trees, management of pests and the like.

[0055] Within the scope of the present invention, target crops and/or useful plants to be protected typically comprise perennial and annual crops, such as berry plants, for example, blackberries, blueberries, cranberries, raspberries and strawberries; cereals, for example, barley, corn, millet, oats, rice, rye, sorghum, triticale and wheat; fibrous plants, for example cotton, flax, hemp, jute and sisal; field crops, for example, sugar and fodder beet, coffee, hops, mustard, rapeseed (canola), poppy, sugar cane, sunflower, tea and tobacco; fruit trees, for example, apple, apricot, avocado, banana, cherry, citrus, nectarine, peach, pear and plum; grasses, e.g., Bermuda grass, blue grass, agrostis, centipede grass, fescue, ryegrass, St. Augustine grass, and Zoysia grass; aromatic herbs, such as basil, borage, chives, coriander, lavender, lovage, mint, oregano, parsley, rosemary, sage and thyme; legumes, e.g. beans, lentils, peas and soybeans; nuts, for example, almonds, cashews, peanut seeds, hazelnuts, peanuts, pecans, pistachios and walnuts; palm trees, e.g. oil palm; ornamental plants, e.g. flowers, shrubs and trees; other trees, for example cocoa, coconut, olive and rubber; vegetables, e.g., asparagus, eggplant, broccoli, cabbage, carrots, cucumber, garlic, lettuce, pumpkin, melon, okra, onion, pepper, potato, pumpkin, rhubarb, spinach and tomato, and vines, e.g., grapes .

[0056] The term “useful plants” should be understood to also include useful plants that have been made tolerant to herbicides such as bromoxynil or classes of herbicides (such as, for example, HPPD inhibitors, ALS inhibitors, for example primisulfuron, prosulfuron and trifloxysulfuron, EPSPS (5-enol-pyrovyl-shikimate-3-phosphate synthase) inhibitors, GS (glutamine synthetase) inhibitors or PPO (protoporphyrinogen-oxidase) inhibitors) as a result of conventional breeding methods or genetic engineering. An example of a crop that has been made tolerant to imidazolinones, e.g. imazamox, by conventional breeding methods (mutagenesis) is Clearfield® summer rapeseed (Canola). Examples of crops that have been made tolerant to herbicides or classes of herbicides by genetic engineering methods include glyphosate- and glufosinate-resistant corn varieties, commercially available under the trademarks RoundupReady®, Herculex I® and LibertyLink®.

[0057] The term “useful plants” should be understood as also including useful plants that have been thereby transformed by the use of recombinant DNA techniques that are capable of synthesizing one or more selectively acting toxins, such as are known, for example, from toxin-producing bacteria, especially those of the Bacillus genus.

[0058] Examples of such plants are: YieldGard® (a variety of apple that expresses a CryIA(b) toxin); YieldGard Rootworm® (a variety of apple that expresses a CryIIIB(b1) toxin); YieldGard Plus® (a variety of apple that expresses a CryIA(b) toxin and a CryIIIB(b1) toxin); Starlink® (a variety of apple that expresses a Cry9(c) toxin); Herculex I® (maize variety that expresses a CryIF(a2) toxin and the enzyme phosphinothricin N-acetyltransferase (PAT) to achieve tolerance to the herbicide glufosinate ammonium); NuCOTN 33B® (cotton variety that expresses a CryIA(c) toxin); Bollgard I® (cotton variety that expresses a CryIA(c) toxin); Bollgard II® (cotton variety that expresses a CryIA(c) toxin and a CryIIA(b) toxin); VIPCOT® (a cotton variety that expresses a VIP toxin); NewLeaf® (potato variety that expresses a CryIIIA toxin); NatureGard® Agrisure® GT Advantage (glyphosate tolerance trait GA21), Agrisure® CB Advantage (corn borer (CB) trait Bt11), Agrisure® RW (corn rootworm trait) and Protecta®.

[0059] The term "crops" should be understood as also including crop plants that have been transformed by the use of recombinant DNA techniques so that they are capable of synthesizing one or more selectively acting toxins, such as are known, e.g. of bacteria that produce toxins, especially those of the Bacillus genus.

[0060] Toxins that can be expressed by such transgenic plants include, for example, insecticidal proteins from Bacillus cereus or Bacillus popilliae, or insecticidal proteins from Bacillus thuringiensis, such as δ-endotoxins, for example, Cry1Ab, Cry1Ac, Cry1F, Cry1Fa2, Cry2Ab, Cry3A, Cry3Bb1 or Cry9C, or vegetative insecticidal proteins (Vip), e.g. Vip1, Vip2, Vip3 or Vip3A, or insecticidal proteins from nematode colonizing bacteria, e.g. Photorhabdus spp. or Xenorhabdus spp., such as Photorhabdus luminescens, Xenorhabdus nematophilus; toxins produced by animals, such as scorpion toxins, arachnid toxins, wasp toxins and other insect-specific neurotoxins; toxins produced by fungi, such as Streptomycetes toxins; plant lectins, such as pea lectins, barley lectins or whitebell lectins; agglutinins; proteinase inhibitors, such as trypsin inhibitors, serine protease inhibitors, patatin, cystatin, papain inhibitors; ribosome inactivating proteins (RIP), such as ricin, maize RIP, abren, lufin, saporin or bryodin; steroid metabolism enzymes such as 3-hydroxysteroid oxidase, ecdysteroid-UDP-glycosyltransferase, cholesterol oxidases, ecdysone inhibitors, HMG-COA reductase, ion channel blockers such as sodium or calcium channel blockers, hormone juvenile esterase, diuretic hormone receptors, stilbene synthase, bibenzyl synthase, chitinases and glucanases.

[0061] Additionally, in the context of the present invention, it should be understood by δ-endotoxins, for example, Cry1Ab, Cry1Ac, Cry1F, Cry1Fa2, Cry2Ab, Cry3A, Cry3Bb1 or Cry9C, or vegetative insecticidal proteins (Vip), for example, Vip1 , Vip2, Vip3 or Vip3A, expressly also hybrid toxins, truncated toxins and modified toxins. Hybrid toxins are produced recombinantly by a new combination of different domains of these proteins (see, for example, WO 02/15701). Truncated toxins, for example a truncated Cry1Ab, are known. In the case of modified toxins, one or more amino acids of the naturally occurring toxin are replaced. In such amino acid substitutions, preferably non-naturally present protease recognition sequences are inserted into the toxin, such as, for example, in the case of Cry3A055, a cathepsin G recognition sequence is inserted into a Cry3A toxin (see WO 03/018810 ).

[0062] Examples of such toxins or transgenic plants capable of synthesizing such toxins are disclosed, for example, in EP-A-0 374 753, WO93/07278, WO95/34656, EP-A-0 427 529, EP-A- 451 878 and WO 03/052073.

[0063] The processes for preparing such transgenic plants are generally known to those skilled in the art and are described, for example, in the publications mentioned above. Deoxyribonucleic acids of the CryI type and their preparation are known, for example, from WO 95/34656, EP-A-0 367 474, EP-A-0 401 979 and WO 90/13651.

[0064] The toxin contained in transgenic plants gives the plants tolerance to harmful insects. Such insects can occur in any taxonomic group of insects, but are especially and commonly found in beetles (Coleoptera), two-winged insects (Diptera) and butterflies (Lepidoptera).

[0065] Transgenic plants that contain one or more genes that encode insecticide resistance and express one or more toxins are known and some of them are commercially available. Examples of such plants are: YieldGard® (a variety of apple that expresses a CrylAb toxin); YieldGard Rootworm® (a variety of apple that expresses a Cry3Bb1 toxin); YieldGard Plus® (maize variety that expresses a Cry1Ab and a Cry3Bb1 toxin); Starlink® (a variety of apple that expresses a Cry9C toxin); Herculex I® (maize variety that expresses a Cry1Fa2 toxin and the enzyme phosphinothricin N-acetyltransferase (PAT) to achieve tolerance to the herbicide glufosinate ammonium); NuCOTN 33B® (cotton variety that expresses a Cry1Ac toxin); Bollgard I® (cotton variety that expresses a Cry1Ac toxin); Bollgard II® (cotton variety that expresses a Cry1Ac and a Cry2Ab toxin); VipCot® (cotton variety that expresses a Vip3A and a Cry1Ab toxin); NewLeaf® (potato variety that expresses a Cry3A toxin); NatureGard®, Agrisure® GT Advantage (glyphosate tolerant trait GA21), Agrisure® CB Advantage (corn borer (CB) trait Bt11) and Protecta®.

[0066] Additional examples of such transgenic crops are: 1. Bt11 corn from Syngenta Seeds SAS, Chemin de l'Hobit 27, F-31 790 St. Sauveur, France, registration number C/FR/96/05/10. Genetically modified Zea mays that has been rendered resistant to attack by the European Corn Borer (Ostrinia nubilalis and Sesamia nonagrioides) by transgenic expression of a truncated Cry1Ab toxin. Bt11 maize also transgenically expresses the PAT enzyme to achieve tolerance to the herbicide glufosinate ammonium. 2. Corn Bt176 from Syngenta Seeds SAS, Chemin de l'Hobit 27, F-31 790 St. Sauveur, France, registration number C/FR/96/05/10. Genetically modified Zea mays that has been rendered resistant to attack by the European corn borer (Ostrinia nubilalis and Sesamia nonagrioides) by transgenic expression of a Cry1Ab toxin. Bt176 maize also transgenically expresses the PAT enzyme to achieve tolerance to the herbicide glufosinate ammonium. 3. Corn MIR604 from Syngenta Seeds SAS, Chemin de l'Hobit 27, F-31 790 St. Sauveur, France, registration number C/FR/96/05/10. Corn that has been made resistant to insects through transgenic expression of a modified Cry3A toxin. This toxin is Cry3A055 modified by insertion of a cathepsin-G-protease recognition sequence. The preparation of such transgenic corn plants is described in WO 03/018810. 4. Corn MON 863 from Monsanto Europe S.A. 270-272 Avenue de Tervuren, B-1150 Brussels, Belgium, registration number C/DE/02/9. MON 863 expresses a Cry3Bb1 toxin and has resistance to certain Coleoptera insects. 5. IPC 531 Cotton from Monsanto Europe S.A. 270-272 Avenue de Tervuren, B-1150 Brussels, Belgium, registration number C/ES/96/02. 6. Corn 1507 from Pioneer Overseas Corporation, Avenue Tedesco, 7 B-1160 Brussels, Belgium, registration number C/NL/00/10. Corn genetically modified to express the Cry1F protein to achieve resistance to certain Lepidoptera insects and the PAT protein to achieve tolerance to the herbicide glufosinate ammonium. 7. Corn NK603 x MON 810 from Monsanto Europe S.A. 270-272 Avenue de Tervuren, B-1150 Brussels, Belgium, registration number C/GB/02/M3/03. It consists of hybrid corn varieties conventionally improved by crossing the genetically modified varieties NK603 and MON 810. Corn NK603 x MON 810 transgenically expresses the CP4 EPSPS protein, obtained from the CP4 strain of Agrobacterium sp., which confers tolerance to the herbicide Roundup® (contains glyphosate), and also a Cry1Ab toxin obtained from Bacillus turingiensis subsp. kurstaki that confers tolerance to certain Lepidoptera, including the European corn borer.

[0067] The compounds of Formula (I) (including any of compounds A.1 to A.43 described in Table A (below) and B.1 to B.24 described in Table B (below)) in accordance with the present invention can be used in the control or prevention of phytopathogenic diseases, especially phytopathogenic fungi (such as Phakopsora pachyrhizi) in soybean plants.

[0068] In particular, transgenic soybean plants express toxins, for example, insecticidal proteins such as delta-endotoxins, for example, Cry1Ac (Cry1Ac Bt protein). Accordingly, they may include transgenic soybean plants comprising event MON87701 (see U.S. Patent No. 8,049,071 and related applications and patents, as well as WO 2014/170327 A1 (e.g., see paragraph [008], reference to Intact soybean RR2 PROTM)) , event MON87751 (U.S. Patent Application Publication No. 2014/0373191) or event DAS-81419 (U.S. Patent No. 8632978 and related applications and patents).

[0069] Other transgenic soybean plants may comprise event SYHT0H2 - HPPD tolerance (U.S. Patent Application Publication No. 2014/0201860 and related applications and patents), event MON89788 - glyphosate tolerance (U.S. Pat. No. 7,632,985 and related applications and patents), event MON87708 - dicamba tolerance (U.S. Patent Application Publication No. US 2011/0067134 and related applications and patents), event DP-356043-5 - glyphosate and ALS tolerance (Patent Application Publication U.S. No. US 2010/0184079 and related applications and patents), event A2704-12 - glufosinate tolerance (U.S. Patent Application Publication No. US 2008/0320616 and related applications and patents), event DP-305423-1 - tolerance the ALS (U.S. Patent Application Publication No. US 2008/0312082 and related applications and patents), event A5547-127 - glufosinate tolerance (U.S. Patent Application Publication No. US 2008/0196127 and related applications and patents), event DAS-40278-9 - tolerance to 2,4-dichlorophenoxyacetic acid and aryloxyphenoxypropionate (see WO 2011/022469, WO 2011/022470, WO 2011/022471 and related applications and patents), event 127 - tolerance to ALS (WO 2010/ 080829 and related applications and patents), event GTS 40-3-2 - tolerance to glyphosate, event DAS-68416-4 - tolerance to 2,4-dichlorophenoxyacetic acid and glufosinate, event FG72 - tolerance to glyphosate and isoxaflutole, event BPS- CV127-9 - ALS tolerance and GU262 - glufosinate tolerance or event SYHT04R - HPPD tolerance.

[0070] Under certain circumstances, the compounds of Formula (I) according to the present invention, when used in the control or prevention of phytopathogenic diseases, especially phytopathogenic fungi (such as Phakopsora pachyrhizi) on soybean plants (in particular any of the transgenic soy plants as described above), may exhibit a synergistic interaction between the active ingredients.

[0071] Additionally, to date, no cross-resistance has been observed between compounds of Formula (I) (including any of compounds A.1 to A.43 described in Table A (below) and B.1 to B.24 described in Table B (below)) and the current fungicidal solutions used to control Phakopsora pachyrhizi.

[0072] In fact, fungicide-resistant strains of Phakopsora pachyrhizi have been reported in the scientific literature, with strains resistant to one or more fungicides of at least each of the following classes of fungicidal modes of action being observed: sterol demethylation inhibitors ( DMI), external quinone inhibitors (QoI) and succinate dehydrogenase inhibitors (SDHI). See for example: "Sensitivity of Phakopsora pachyrhizi towards quinone-outside-inhibitors and demethylation-inhibitors, and corresponding resistance mechanisms." Schmitz HK et al., Pest Manag Sci (2014) 70: 378-388; "First detection of an SDH variant with reduced SDHI sensitivity in Phakopsora pachyrhizi" Simões K et al, J Plant Dis Prot (2018) 125: 212; “Competitive fitness of Phakopsora pachyrhizi isolates with mutations in the CYP51 and CYTB genes”. Klosowski AC et al., Phytopathology (2016) 106: 1278-1284; “Detection of the F129L mutation in the cytochrome b gene in Phakopsora pachyrhizi". Klosowski AC et al., Pest Manag Sci (2016) 72: 1211-1215.

[0073] Thus, in a preferred embodiment, the compounds of Formula (I) (including any of compounds A.1 to A.43 described in Table A (below), compounds B.1 to B.24 described in Table B (below)), or fungicidal compositions according to the present invention comprising a compound of Formula (I), are used to control Phakopsora pachyrhizi that are resistant to one or more fungicides of any of the following MoA classes of fungicides: demethylation inhibitors of sterols (DMI), external quinone inhibitors (QoI) and succinate dehydrogenase inhibitors (SDHI).

[0074] The compounds of Formula (I) (including any of compounds A.1 to A.43 described in Table A (below) and B.1 to B.24 described in Table B (below)) or fungicidal compositions of According to the present invention comprising a compound of Formula (I) can be used in the control or prevention of phytopathogenic diseases, especially phytopathogenic fungi (such as Phakopsora pachyrhizi) in soybean plants. In particular, certain varieties of Elite soybean plants are known in the scientific literature where stacks of the R gene, conferring a degree of immunity or resistance to specific Phakopsora pachyrhizi, have been introduced into the plant genome, see, for example: “Fighting Asian Soybean Rust” , Langenbach C, et al., Front Plant Science 7 (797) 2016).

[0075] An elite plant is any plant from an elite line, so an elite plant is a plant representative of an elite variety. Non-limiting examples of elite soybean varieties that are commercially available to farmers or soybean breeders include: AG00802, A0868, AG0902, A1923, AG2403, A2824, A3704, A4324, A5404, AG5903, AG6202 AG0934; AG1435; AG2031; AG2035; AG2433; AG2733; AG2933; AG3334; AG3832; AG4135; AG4632; AG4934; AG5831; AG6534; and AG7231 (Asgrow Seeds, Des Moines, Iowa, USA); BPR0144RR, BPR 4077NRR and BPR 4390NRR (Bio Plant Research, Camp Point, Ill., USA); DKB17-51 and DKB37-51 (DeKalb Genetics, DeKalb, Ill., USA); DP 4546 RR, and DP 7870 RR (Delta & Pine Land Company, Lubbock, Tex., USA); JG 03R501, JG 32R606C ADD and JG 55R503C (JGL Inc., Greencastle, Ind., USA); NKS 13-K2 (NK Division of Syngenta Seeds, Golden Valley, Minnesota, USA); 90M01, 91M30, 92M33, 93M11, 94M30, 95M30, 97B52, P008T22R2; P16T17R2; P22T69R; P25T51R; P34T07R2; P35T58R; P39T67R; P47T36R; P46T21R; and P56T03R2 (Pioneer Hi-Bred International, Johnston, Iowa, USA); SG4771NRR and SG5161NRR/STS (Soygenetics, LLC, Lafayette, Ind., USA); S00-K5, S11-L2, S28-Y2, S43-B1, S53-A1, S76-L9, S78-G6, S0009-M2; S007-Y4; S04-D3; S14-A6; S20- T6; S21-M7; S26-P3; S28-N6; S30-V6; S35-C3; S36-Y6; S39-C4; S47-K5; S48-D9; S52-Y2; S58-Z4; S67-R6; S73-S8; and S78-G6 (Syngenta Seeds, Henderson, Ky., USA); Richer (Northstar Seed Ltd. Alberta, CA); 14RD62 (Stine Seed Co. Ia., USA), or Armor 4744 (Armor Seed, LLC, Ar., USA).

[0076] Thus, in an additional preferred embodiment, the compounds of Formula (I) (including any of compounds A.1 to A.43 described in Table A (below) and B.1 to B.24 described in Table B (below)), or fungicidal compositions according to the present invention comprising a compound of Formula (I), are used to control Phakopsora pachyrhizi (including fungicide-resistant strains thereof, as outlined above) on Elite soybean plant varieties in which R gene stacks, conferring a degree of immunity or resistance to specific Phakopsora pachyrhizi, have been introduced into the plant genome. Numerous benefits can be expected to result from said use, e.g., improved biological activity, an advantageous or broader spectrum of activity (including sensitive and resistant strains of Phakopsora pachyrhizi), an increased safety profile, improved crop tolerance, synergistic interactions or potentiating properties, improved onset of action or a longer lasting residual activity, a reduction in the number of applications and/or a reduction in the application rate of compounds and compositions required for effective control of the phytopathogen (Phakopsora pachyrhizi), thereby allowing beneficial resistance management practices, reduced environmental impact and reduced operator exposure.

[0077] The term “locus” as used here means fields in which or on which plants are growing or where seeds of cultivated plants are sown or where seed will be placed in the soil. Includes soil, seeds and seedlings, as well as established vegetation.

[0078] The term “plants” refers to all physical parts of a plant, including seeds, seedlings, young plants, roots, tubers, stems, stems, foliage and fruits.

[0079] It is understood that the term “plant propagation material” designates generative parts of the plant, such as seeds, which can be used for the multiplication of the latter, and vegetative material, such as cuttings or tubers, for example potatoes. For example, seeds (in the strict sense), roots, fruits, tubers, bulbs, rhizomes and parts of plants may be mentioned. Germinated plants and young plants that will be transplanted after germination or after emergence from the soil may also be mentioned. These young plants can be protected before transplanting by a full or partial immersion treatment. Preferably, “plant propagation material” is understood to mean seeds.

[0080] The compounds of Formula (I) can be used in an unmodified form or, preferably, in conjunction with the adjuvants conventionally employed in the formulation technique. For this purpose, they can be conveniently formulated in a known manner into emulsifiable concentrates, coatable pastes, directly sprayable or dilutable solutions or suspensions, diluted emulsions, wettable powders, soluble powders, dusts, granules and also encapsulations, for example, in polymeric substances. Like the type of compositions, application methods, such as spraying, atomization, dusting, dispersion, coating or pouring, are chosen according to the intended objectives and the prevailing circumstances. The compositions may also contain additional adjuvants such as stabilizers, defoamers, viscosity regulators, binders or stickiness promoters as well as fertilizers, micronutrient donors or other formulations to obtain special effects.

[0081] Suitable carriers and adjuvants, for example for agricultural use, may be solid or liquid and are substances useful in formulation technology, for example, natural or regenerated mineral substances, solvents, dispersants, wetting agents, stickiness promoters, thickeners , binders or fertilizers. Such carriers are described, for example, in WO 97/33890.

[0082] Suspension concentrates are aqueous formulations in which finely divided solid particles of the active compound are suspended. Such formulations include anti-settling agents and dispersing agents and may additionally include a wetting agent to increase activity, as well as an antifoam and a crystal growth inhibitor. In use, these concentrates are diluted in water and typically applied as a spray to the area to be treated. The amount of active ingredient can vary from 0.5% to 95% of the concentrate.

[0083] Wettable powders are in the form of finely divided particles that disperse quickly in water or other liquid carriers. The particles contain the active ingredient trapped in a solid matrix. Typical solid matrices include Fuller's earth, kaolin clays, silicas, and other readily moistened organic or inorganic solids. Wettable powders typically contain from 5% to 95% of the active ingredient plus a small amount of wetting, dispersing or emulsifying agent.

[0084] Emulsifiable concentrates are homogeneous liquid compositions dispersible in water or other liquid and may consist entirely of the active compound with a liquid or solid emulsifying agent, or may also contain a liquid carrier, such as xylene, heavy aromatic naphthas, isophorone and other organic solvents non-volatile. In use, these concentrates are dispersed in water or another liquid and typically applied as a spray to the area to be treated. The amount of active ingredient can vary from 0.5% to 95% of the concentrate.

[0085] Granular formulations include both extrudates and relatively coarse particles and are usually applied without dilution to the area where treatment is required. Typical carriers for granular formulations include sand, Fuller's earth, attapulgite clay, bentonite clays, montmorillonite clay, vermiculite, perlite, calcium carbonate, brick, pumice, pyrophyllite, kaolin, dolomite, gypsum, wood flour, crushed corn cobs, crushed peanut shells, sugars, sodium chloride, sodium sulfate, sodium silicate, sodium borate, magnesia, mica, iron oxide, zinc oxide, titanium oxide, antimony oxide, cryolite, gypsum, diatomaceous earth, calcium sulfate and other organic or inorganic materials that absorb or can be coated with the active compound. Granular formulations typically contain 5% to 25% active ingredients which may include surfactants such as heavy aromatic naphthas, kerosene and other petroleum fractions, or vegetable oils, and/or adhesives such as dextrins, glue or synthetic resins.

[0086] Dusts are free-flowing mixtures of the active ingredient with finely divided solids such as talc, clays, flours and other organic and inorganic solids that act as dispersants and carriers.

[0087] Microcapsules are typically droplets or granules of the active ingredient enclosed in an inert porous shell that allows the enclosed material to escape into the surroundings at controlled rates. Encapsulated droplets are typically 1 to 50 microns in diameter. The enclosed liquid typically constitutes 50 to 95% of the weight of the capsule and may include solvent in addition to the active compound. Encapsulated granules are generally porous granules with porous membranes sealing the granule pore openings, trapping the active species in liquid form within the granule pores. The beads typically range from 1 millimeter to 1 centimeter and preferably 1 to 2 millimeters in diameter. Granules are formed by extrusion, agglomeration or pelletization, or occur naturally. Examples of such materials are vermiculite, sintered clay, kaolin, attapulgite clay, sawdust and granular coal. Shell or membrane materials include natural and synthetic rubbers, cellulosic materials, styrene-butadiene copolymers, polyacrylonitriles, polyacrylates, polyesters, polyamides, polyureas, polyurethanes and starch xanthates.

[0088] Other formulations useful for agrochemical applications include simple solutions of the active ingredient in a solvent in which it is completely soluble at the desired concentration, such as acetone, alkylated naphthalenes, xylene and other organic solvents. Pressurized sprayers can also be used, in which the active ingredient is dispersed in finely divided form due to the vaporization of a low boiling point dispersant solvent carrier.

[0089] Suitable agricultural adjuvants and carriers that are useful in formulating the compositions of the invention into the types of formulations described above are well known to those skilled in the art.

[0090] Liquid carriers that may be employed include, for example, water, toluene, xylene, petroleum naphtha, vegetable oil, acetone, methyl ethyl ketone, cyclohexanone, acetic anhydride, acetonitrile, acetophenone, amyl acetate, 2-butanone, chlorobenzene, cyclohexane, cyclohexanol, alkyl acetates, diacetone alcohol, 1,2-dichloropropane, diethanolamine, p-diethylbenzene, diethylene glycol, diethylene glycol abietate, diethylene glycol butyl ether, diethylene glycol ethyl ether, diethylene glycol ether diethylene glycol methyl, N,N-dimethylformamide, dimethyl sulfoxide, 1,4-dioxane, dipropylene glycol, dipropylene glycol methyl ether, dipropylene glycol dibenzoate, diproxytol, alkylpyrrolidinone, ethyl acetate, 2-ethylhexanol, ethylene carbonate, 1, 1,1- trichloroethane, 2-heptanone, alpha-pinene, d-limonene, ethylene glycol, ethylene glycol butyl ether, ethylene glycol methyl ether, gamma-butyrolactone, glycerol, glycerol diacetate, glycerol monoacetate, glycerol triacetate, hexadecane, hexylene glycol, isoamyl acetate, isobornyl acetate, isooctane, isophorone, isopropylbenzene, isopropyl myristate, lactic acid, laurylamine, mesityl oxide, methoxypropanol, methylisoamylketone, methylisobutylketone, methyl laurate, methyl octanoate, oleate methyl, methylene chloride, m-xylene, n-hexane, n-octylamine, octadecanoic acid, octylamine acetate, oleic acid, oleylamine, o-xylene, phenol, polyethylene glycol (PEG400), propionic acid, propylene glycol, monoethyl ether of propylene glycol, p-xylene, toluene, triethyl phosphate, triethylene glycol, xylenesulfonic acid, paraffin, mineral oil, trichloroethylene, perchloroethylene, ethyl acetate, amyl acetate, butyl acetate, methanol, ethanol, isopropanol and alcohols of higher molecular weight high, such as amyl alcohol, tetrahydrofurfuryl alcohol, hexanol, octanol, etc., ethylene glycol, propylene glycol, glycerin and N-methyl-2-pyrrolidinone. Water is typically the carrier of choice for diluting concentrates.

[0091] Suitable solid carriers include, for example, talc, titanium dioxide, pyrophyllite clay, silica, attapulgite clay, diatomite, chalk, diatomaceous earth, lime, calcium carbonate, bentonite clay, Fuller's earth, shells cottonseed, wheat flour, soybean flour, pumice, wood flour, walnut shell flour and lignin.

[0092] A wide range of surface-active agents are advantageously used in said liquid and solid compositions, especially those planned to be diluted with a carrier before application. These agents, when used, typically comprise from 0.1% to 15% by weight of the formulation. They can be anionic, cationic, non-ionic or polymeric in nature and can be used as emulsifying agents, wetting agents, suspending agents or for other purposes. Typical surfactants include alkyl sulfate salts, such as diethanolammonium lauryl sulfate; alkylarylsulfonate salts, such as calcium dodecylbenzenesulfonate; alkylphenol-alkylene oxide addition products such as nonylphenol C18-ethoxylate; alcohol-alkylene oxide addition products such as C16-tridecyl alcohol ethoxylate; soaps, such as sodium stearate; alkylnaphthalenesulfonate salts, such as sodium dibutylnaphthalenesulfonate; dialkyl esters of sulfosuccinate salts, such as sodium di(2-ethylhexyl)sulfosuccinate; sorbitol esters, such as sorbitol oleate; quaternary amines, such as lauryltrimethylammonium chloride; polyethylene glycol esters of fatty acids, such as polyethylene glycol stearate; block copolymers of ethylene oxide and propylene oxide; and salts of mono- and dialkyl phosphate esters.

[0093] Other adjuvants commonly used in agricultural compositions include crystallization inhibitors, viscosity modifiers, suspending agents, spray droplet modifiers, pigments, antioxidants, foaming agents, antifoam agents, light blocking agents, compatibilizing agents, antifoam agents, sequestering agents, neutralizing agents and buffers, corrosion inhibitors, colorants, flavorings, spreading agents, penetration aids, micronutrients, emollients, lubricants and adhesive agents.

[0094] Additionally, other biocidal active ingredients or compositions can be combined with the compositions of the invention and used in the methods of the invention and applied simultaneously or sequentially with the compositions of the invention. When applied simultaneously, these additional active ingredients can be formulated together with the compositions of the invention or mixed, for example, in the spray tank. These additional biocidal active ingredients may be fungicides, herbicides, insecticides, bactericides, acaricides, nematicides and/or plant growth regulators.

[0095] Pesticide agents are referred to here using their common name; are known, for example, from “The Pesticide Manual”, 15th Edition British Crop Protection Council 2009.

[0096] Additionally, the compositions of the invention can also be applied with one or more inducers of systemically acquired resistance (“SAR” inducer). SAR inducers are known and described, for example, in United States Patent No. US 6,919,298 and include, for example, salicylates and the commercial SAR inducer acibenzolar-S-methyl.

[0097] The compounds of Formula (I) are normally used in the form of agrochemical compositions and can be applied to the crop or plant area to be treated, simultaneously or successively with additional compounds. These additional compounds can be, for example, fertilizers or micronutrient donors or other preparations that influence plant growth. They may also be selective herbicides or non-selective herbicides, as well as insecticides, fungicides, bactericides, nematicides, molluscicides or mixtures of several of these preparations, if desired in conjunction with additional carriers, surfactants or application-promoting adjuvants commonly used in the formulation technique.

[0098] The compounds of Formula (I) can be used in the form of compositions (fungicides) to control or protect against phytopathogenic microorganisms, comprising as an active ingredient at least one compound of Formula (I) or at least one preferred individual compound as defined here, in free form or in agrochemically usable salt form, and at least one of the above-mentioned adjuvants.

[0099] The invention therefore provides a composition, preferably a fungicidal composition, comprising at least one compound of Formula (I), an agriculturally acceptable carrier and optionally an adjuvant. An acceptable agricultural conveyor is, for example, a conveyor that is suitable for agricultural use. Agricultural conveyors are well known in the art. Preferably, said composition may comprise at least one or more pesticide-active compounds, for example, an additional fungicidal active ingredient in addition to the compound of Formula (I).

[0100] The compound of Formula (I) may be the only active ingredient of a composition or may be mixed with one or more additional active ingredients such as a pesticide, fungicide, synergist, herbicide or plant growth regulator, when appropriate. . An additional active ingredient may, in some cases, result in unexpected synergistic activities.

[0101] Examples of suitable additional active ingredients include the following: acycloamino acid fungicides, aliphatic nitrogen fungicides, amide fungicides, anilide fungicides, antibiotic fungicides, aromatic fungicides, arsenic fungicides, arylphenylketone fungicides, benzamide fungicides, fungicides benzanilide fungicides, benzimidazole fungicides, benzothiazole fungicides, botanical fungicides, bridged diphenyl fungicides, carbamate fungicides, carbanylate fungicides, conazole fungicides, copper fungicides, dicarboximide fungicides, dinitrophenol fungicides, dithiocarbamate fungicides, copper fungicides, dithiolane, furamide fungicides, furanilide fungicides, hydrazide fungicides, imidazole fungicides, mercury fungicides, morpholine fungicides, organophosphate fungicides, organotin fungicides, oxathiin fungicides, oxazole fungicides, phenylsulfamide fungicides, polysulfide fungicides, pyrazole, pyridine fungicides, pyrimidine fungicides, pyrrole fungicides, quaternary ammonium fungicides, quinoline fungicides, quinone fungicides, quinoxaline fungicides, strobilurin fungicides, sulfonanilide fungicides, thiadiazole fungicides, thiazole fungicides, thiazolidine fungicides , thiocarbamate fungicides, thiophene fungicides, triazine fungicides, triazole fungicides, triazolopyrimidine fungicides, urea fungicides, valinamide fungicides and zinc fungicides.

[0102] Examples of suitable additional active ingredients also include the following: (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methane-naphthalen-5-yl)-3-difluoromethyl acid amide -1-methyl-1H-pyrazol-4-carboxylic acid, methoxy-[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-amide 3-difluoromethyl-1-methyl-1H-pyrazol- 4-carboxylic, 1-methyl-3-difluoromethyl-1H-pyrazol-4-carboxylic acid (2-dichloromethylene-3-ethyl-1-methyl-indan-4-yl)-amide (107295771-1), (4 '-methylsulfanyl-biphenyl-2-yl)-amide of 1-methyl-3-difluoromethyl-1H-pyrazol-4-carboxylic acid, [2-(2,4-dichloro-phenyl)-2-methoxy-1-methyl 1-methyl-3-difluoromethyl-4H-pyrazol-4-carboxylic acid-ethyl]-amide, (5-Chloro-2,4-dimethyl-pyridin-3-yl)-(2,3,4-trimethoxy- 6-methyl-phenyl)-methanone, (5-Bromo-4-chloro-2-methoxy-pyridin-3-yl)-(2,3,4-trimethoxy-6-methyl-phenyl)-methanone, 2-{ 2-[(E)-3-(2,6-Dichloro-phenyl)-1-methyl-prop-2-en-(E)-ylideneamino-oxymethyl]-phenyl}-2-[(Z)-methoxy- imino]-N-methyl-acetamide, 3-[5-(4-Chloro-phenyl)-2,3-dimethyl-isoxazolidin-3-yl]-pyridine, (E)-N-methyl-2-[2- (2,5-dimethylphenoxymethyl)phenyl]-2-methoxy-iminoacetamide, 4-bromo-2-cyano-N,N-dimethyl-6-trifluoromethylbenzimidazol-1-sulfonamide, α-[N-(3-chloro- 2, 6-xylyl)-2-methoxyacetamido]-yl-butyrolactone, 4-chloro-2-cyano-N,N-dimethyl-5-p-tolylimidazol-1-sulfonamide, N-allyl-4,5-dimethyl-2- trimethylsilylthiophene-3-carboxamide, N-(1-cyano-1,2-dimethylpropyl)-2-(2,4-dichlorophenoxy)propionamide, N-(2-methoxy-5-pyridyl)-cyclopropanecarboxamide, (.+-. )-cis-1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)-cycloheptanol, 2-(1-tert-butyl)-1-(2-chlorophenyl )-3-(1,2,4-triazol-1-yl)-propan-2-ol, 2',6'-dibromo-2-methyl-4-trifluoromethoxy-4'-trifluoromethyl-1,3-thiazole -5-carboxanilide, 1-imidazolyl-1-(4'-chlorophenoxy)-3,3-dimethylbutan-2-one, (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy ]phenyl]3-methylmethoxyacrylate, (E)-2-[2-[6-(2-thioamidophenoxy)pyrimidin-4-yloxy]phenyl]-3-methylmethoxyacrylate, (E)-2-[2- Methyl [6-(2-fluorophenoxy)pyrimidin-4-yloxy]phenyl]-3-methoxyacrylate, (E)-2-[2-[6-(2,6-difluorophenoxy)pyrimidin-4-yloxy]phenyl] Methyl -3-methoxyacrylate, (E)-2-[2-[3-(pyrimidin-2-yloxy)phenoxy]phenyl]-3-methylmethoxyacrylate, (E)-2-[2-[3-( Methyl 5-methylpyrimidin-2-yloxy)-phenoxy]phenyl]-3-methoxyacrylate, (E)-2-[2-[3-(phenylsulfonyloxy)phenoxy]phenyl-3-methyl methoxyacrylate, (E) Methyl -2-[2-[3-(4-nitrophenoxy)phenoxy]phenyl]-3-methoxyacrylate, (E)-2-[2-phenoxyphenyl]-3-methylmethoxyacrylate, (E)-2-[ Methyl 2-(3,5-dimethyl-benzoyl)pyrrol-1-yl]-3-methoxyacrylate, (E)-2-[2-(3-methoxyphenoxy)phenyl]-3-methylmethoxyacrylate, (E) -2-[2-(2-phenylethen-1-yl)-phenyl]-3- methyl methoxyacrylate, (E)-2-[2-(3,5-dichlorophenoxy)pyridin-3-yl]-3- methyl methoxyacrylate, (E)-2-(2-(3-(1,1,2,2-tetrafluoroethoxy)phenoxy)phenyl)-3- methyl methoxyacrylate, (E)-2-(2-[3- (alpha-hydroxybenzyl)phenoxy]phenyl)-methyl 3-methoxyacrylate, (E)-2-(2-(4-phenoxypyridin-2-yloxy)phenyl)-methyl 3-methoxyacrylate, (E)-2-[ 2-(3-n-propyloxy-phenoxy)phenyl]-3-methyl methoxyacrylate, (E)-2-[2-(3-isopropyloxyphenoxy)phenyl]-3-methyl methoxyacrylate, (E)- 2-[ Methyl 2-[3-(2-fluorophenoxy)phenoxy]phenyl]-3-methoxyacrylate, (E)-2-[2-(3-ethoxyphenoxy)phenyl]-3-methylmethoxyacrylate, (E)-2- Methyl [2-(4-tert-butyl-pyridin-2-yloxy)phenyl]-3-methoxyacrylate, (E)-2-[2-[3-(3-cyanophenoxy)phenoxy]phenyl]-3-methoxyacrylate methyl, (E)- methyl 2-[2-[(3-methyl-pyridin-2-yloxymethyl)phenyl]-3-methoxyacrylate, (E)-2-[2-[6-(2-methyl- phenoxy)pyrimidin-4-yloxy]phenyl]-methyl 3-methoxyacrylate, (E)-2-[2-(5-bromo-pyridin-2-yloxymethyl)phenyl]-methyl 3-methoxyacrylate, (E)- Methyl 2-[2-(3-(3-iodopyridin-2-yloxy)phenoxy)phenyl]-3-methoxyacrylate, (E)-2-[2-[6-(2-chloropyridin-3-yloxy)pyrimidin Methyl -4-yloxy]phenyl]-3-methoxyacrylate, (E),(E)-2-[2-(5,6-dimethylpyrazin-2-ylmethyloxyminomethyl)phenyl]-methyl 3-methoxyacrylate, (E) - Methyl 2-{2-[6-(6-methylpyridin-2-yloxy)pyrimidin-4-yloxy]phenyl}-3-methoxy-acrylate, (E),(E)-2-{2-(3 - methyl methoxyphenyl)methyloxyminomethyl]-phenyl}-3-methoxyacrylate, (E)-2-{2-(6-(2-azidophenoxy)-pyrimidin-4-yloxy]phenyl}-methyl 3-methoxyacrylate, (E ),(E)-2-{2-[6-phenylpyrimidin-4-yl)-methyloxyminomethyl]phenyl}-3-methyl methoxyacrylate, (E),(E)-2-{2-[(4-chlorophenyl )- methyloxyminomethyl]-phenyl}-3-methyl methoxyacrylate, (E)- 2-{2-[6-(2-n-propylphenoxy)-1,3,5-triazin-4-yloxy]phenyl}-3 - methyl methoxyacrylate, (E),(E)-2-{2-[(3-nitrophenyl)methyloxyminomethyl]phenyl}-3-methyl methoxyacrylate, 3-chloro-7-(2-aza-2,7, 7-trimethyl-oct-3-en-5-yne), 2,6-dichloro-N-(4-trifluoromethylbenzyl)-benzamide, 3-iodo-2-propynyl alcohol, 4-chlorophenyl-3-iodopropargylformal, ethylcarbamate 3-bromo-2,3-diiodo-2-propenyl, 2,3,3-triiodoallyl alcohol, 3-bromo-2,3-diiodo-2-propenyl alcohol, 3- n-butylcarbamate iodo-2-propynyl, 3-iodo-2-propynyl n-hexylcarbamate, 3-iodo-2-propynyl cyclohexyl carbamate, 3-iodo-2-propynyl phenylcarbamate; phenol derivatives such as tribromophenol, tetrachlorophenol, 3-methyl-4-chlorophenol, 3,5-dimethyl-4-chlorophenol, phenoxyethanol, dichlorophene, o-phenylphenol, m-phenylphenol, p-phenylphenol, 2-benzyl-4- chlorophenol, 5-hydroxy-2(5H)-furanone; 4,5-dichlorodithiazolinone, 4,5- benzodithiazolinone, 4,5-trimethylenedithiazolinone, 4,5-dichloro-(3H)-1,2-dithiol-3-one, 3,5-dimethyl-tetrahydro-1, 3,5-Thiadiazino-2-thione, N-(2-p-chlorobenzoylethyl)-hexamine chloride, acibenzolar, acipetacs, alanicarb, albendazole, aldimorph, allicin, allyl alcohol, ametoctradine, amisulbrom, amobam, ampropilphos, anilazine, asomate , aureofungin, azaconazole, azafendin, azitiram, azoxystrobin, barium polysulfide, benalaxyl, benalaxyl-M, benodanil, benomyl, benquinox, bentaluron, bentiavalicarb, bentiazole, benzalkonium chloride, benzamacril, benzamorph, benzohydroxamic acid, benzovindiflupyr, berberine, betoxazine, biloxazole, binapacryl, biphenyl, bitertanol, bitionol, bixaphene, blasticidin-S, boscalid, bromothalonil, bromuconazole, bupyrimate, butiobate, calcium butylamine polysulfide, Captafol, Captan, carbamorph, carbendazim, carbendazim hydrochloride, carboxine, carpropamide, carvone, CGA41396, CGA41397, quinomethionate, chitosan, clobenthiazone, chloraniformethane, chloranil, chlorphenazole, chloroneb, chloropicrin, chlorothalonil, chlorozolinate, clozolinate, climbazole, clotrimazole, clozilacon, copper-containing compounds such as copper acetate, copper carbonate, copper hydroxide , copper naphthenate, copper oleate, copper oxychloride, copper oxyquinolate, copper silicate, copper sulfate, copper thallate, copper zinc chromate and Bordeaux mixture, cresol, kofraneb, cuprobam, cuprous oxide, cyazofamide, cyclafuramide , cycloheximide, cyflufenamide, cymoxanil, cipendazole, cyproconazole, cyprodinil, dazomet, debacarb, decafentin, dehydroacetic acid, di-2-pyridyl disulfide 1,1'-dioxide, diclofluanid, diclomezine, diclone, dichloran, dichlorophene, diclozolin , diclobutrazol, diclocimet, dietofencarb, difenoconazole, difenzoquat, diflumetrim, O,O-diiso-propyl-S-benzyl thiophosphate, dimefluazole, dimethaclone, dimetconazole, dimethomorph, dimetirimol, diniconazole, diniconazol-M, dinobuton, dinocap, dinocton , dinopenton, dinosulfon, dinoterbon, diphenylamine, dipyrithione, disulfiram, dictatorylimphos, dithianon, dithioether, dodecyldimethylammonium chloride, dodemorph, dodicine, dodine, doguadine, drazoxolon, edifenfos, enestroburin, epoxiconazole, etaconazole, etem, etaboxam, ethyrimole, ethoxyquin, ethylicine , ethyl (Z)-N-benzyl-N-([methyl(methyl-thioethylideneamino-oxycarbonyl)amino]thio)-β-alaninate, etridiazole, famoxadone, fenamidone, fenaminosulf, fenapanil, fenarimol, fenbuconazole, fenfuram, fenexamide, fenitropane, fenoxanil, fenpiclonil, fenpicoxamide, fenpropidine, fenpropimorph, fenpyrazamine, fentin acetate, fentin hydroxide, ferbam, ferimzone, fluazinam, fludioxonil, flumetover, flumorph, flupicolide, fluopyram, fluoroimide, fluotrimazole, fluoxastrobin, fluquinconazole, flusilazole, flusulfamide, flutanil, flutolanil, flutriafol, fluxapiroxad, folpet, formaldehyde, fosetyl, fuberidazole, furalaxil, furametpir, furcarbanil, furconazole, furfural, furmeciclox, furophanate, gliodine, griseofulvin, guazatine, halacrinate, hexachlorobenzene, hexachlorobutadiene, hexachlorophene, hexaconazole, hexylthiophos, hydrar gaphene, hydroxy-isoxazole, himexazol, imazalil, imazalil sulfate, imibenconazole, iminoctadine, iminoctadine triacetate, inezin, iodocarb, ipconazole, ipfentrifluconazole, iprobenfos, iprodione, iprovalicarb, isopropanylbutyl carbamate, isoprothiolane, isopyrazam, isotianil, isovaledione, izopamphos, kasugamycin, cresoxim-methyl, LY186054, LY211795, LY248908, mancozeb, mandipropamide, maneb, mebenil, mecarbinzide, mefenoxam, mefentrifluconazole, mepanipirim, mepronil, mercuric chloride, mercurous chloride, meptildinocap, metalaxyl, metalaxyl-M, metam, metazoxolon, met conazole, metasulfocarb, metfuroxam, methyl bromide, methyl iodide, methyl isothiocyanate, metiram, metiram-zinc, metominostrobin, metrafenone, metsulfovax, milneb, moroxidine, myclobutanil, myclozoline, nabam, natamycin, neoasozin, nickel dimethyldithiocarbamate, nitrostyrene, nitrotal-iso- propyl, nuarimol, octylinone, ofurace, organomercury compounds, orisastrobin, ostol, oxadixyl, oxasulfuron, oxathiapiproline, copper-oxina, oxolinic acid, oxpoconazole, oxycarboxin, parinol, pefurazoate, penconazole, pencycuron, penflufen, pentachlorophenol, penthiopyrad, fenamacril, oxide of phenazine, phosdiphene, fosetyl-Al, phosphorus acids, phthalide, picoxystrobin, piperaline, polycarbamate, polyoxin D, polyoxrim, poliram, probenazole, prochloraz, procymidone, propamidine, propamocarb, propiconazole, propinab, propionic acid, proquinazide, prothiocarb, prothioconazole , pidiflumetofen, pyracarbolide, pyraclostrobin, pyrametrostrobin, pyraoxystrobin, pyrazofos, pyribencarb, pyridinitrile, pyrifenox, pyrimethanil, pyriophenone, piroquilon, piroxichlor, pyroxifur, pyrrolnitrin, quaternary ammonium compounds, quinacetol, quinazamide, quinconazole, quinomethionate, quinoxifene, quintazene , rabenzazole, santonin, sedaxane, siltiofam, simeconazole, sipconazole, sodium pentachlorophenate, spiroxamine, streptomycin, sulfur, sultropene, tebuconazole, tebfloquine, teclophthalam, technazene, tecoram, tetraconazole, thiabendazole, thiadifluor, ticiophene, thifluzamide, 2-(thiocianomethylthio)benzothiazole, thiophanate - methyl, tioquinox, thiram, tiadinil, timibenconazole, thioximide, tolclofos-methyl, tolylfluanide, triadimefon, triadimenol, triamiphos, triarimol, triazbutyl, triazoxide, tricyclazole, tridemorph, trifloxystrobin, triflumazol, triforin, triflumizole, triticonazole, uniconazole, urbacid, validamycin , valifenalate, vapam, vinclozolin, zarilamide, zineb, ziram and zoxamide.

[0103] The compounds of the invention can also be used in combination with anthelmintic agents. Such anthelmintic agents include compounds selected from the class of macrocyclic lactone compounds, such as derivatives of ivermectin, avermectin, abamectin, emamectin, eprinomectin, doramectin, selamectin, moxidectin, nemadectin and milbemycin, as described in EP-357460, EP444964 and EP -594291. Additional anthelmintic agents include semi-synthetic and biosynthetic avermectin/milbemycin derivatives, such as those described in US-5015630, WO-9415944 and WO-9522552. Additional anthelmintic agents include the benzimidazoles such as albendazole, cambendazole, fenbendazole, flubendazole, mebendazole, oxfendazole, oxybendazole, parbendazole and other members of the class. Additional anthelmintic agents include imidazothiazoles and tetrahydropyrimidines such as tetramisole, levadamisole, pyrantel pamoate, oxantel or morantel. Additional anthelmintic agents include flukicides, such as triclabendazole and clorsulon, and cestocides, such as praziquantel and epsiprantel.

[0104] The compounds of the invention can be used in combination with derivatives and analogues of the paraherquamide/marcfortin class of anthelmintic agents, as well as antiparasitic oxazolines such as those disclosed in US-5478855, US-4639771 and DE-19520936 .

[0105] The compounds of the invention can be used in combination with derivatives and analogues of the general class of dioxomorpholine antiparasitic agents as described in WO 96/15121 and also with anthelmintic active cyclic depsipeptides such as those described in WO 96/11945, WO 93/19053, WO 93/25543, EP 0 626 375, EP 0 382 173, WO 94/19334, EP 0 382 173 and EP 0 503 538.

[0106] The compounds of the invention can be used in combination with other ectoparasiticides; for example, fipronil; pyrethroids; organophosphates; insect growth regulators such as lufenuron; ecdysone agonists such as tebufenozide and the like; neonicotinoids such as imidacloprid and the like.

[0107] The compounds of the invention can be used in combination with terpene alkaloids, for example, those described in International Patent Application Publication Numbers WO 95/19363 or WO 04/72086, particularly the compounds disclosed therein.

[0108] Other examples of such biologically active compounds with which the compounds of the invention can be used in combination include the following, but are not restricted to these: Organophosphates: acephate, azamethiphos, azinphos-ethyl, azinphos-methyl, bromophos, bromophos -ethyl, cadusaphos, chlorethoxyphos, chlorpyrifos, chlorfenvinphos, chlormephos, demeton, demeton-S-methyl, demeton-S-methylsulfone, dialiphos, diazinon, dichlorvos, dicrotophos, dimethoate, disulfoton, ethion, etoprophos, etrymphos, famfur, fenamiphos, fenitrothion , fensulfothion, fenthion, flupyrazophos, phonofos, formotion, fosthiazate, heptenophos, isazophos, isothioate, isoxation, malathion, metacriphos, methamidophos, metidathion, methyl-parathion, mevinphos, monocrotophos, nalede, omethoate, oxidemeton-methyl, paraoxon, parathion, parathion -methyl, phentoate, fosalone, phospholane, phosphocarb, phosmet, phosfamidon, phorate, phoxim, pirimiphos, pirimiphos-methyl, profenofos, propaphos, proetamphos, prothiophos, pyraclophos, pyridapenthion, quinalphos, sulprophos, temefos, terbufos, tebupyrimphos, tetrachlorvinphos, timeton , triazophos, trichlorfon, vamidothion. Carbamates: alanicarb, aldicarb, 2-sec-butylphenyl methylcarbamate, benfuracarb, carbaryl, carbofuran, carbosulfan, chlorethocarb, ethiofencarb, fenoxycarb, fenthiocarb, furatiocarb, HCN-801, isoprocarb, indoxacarb, methiocarb, methomyl, 5-methyl-m- cumenylbutyryl(methyl)carbamate, oxamyl, pirimicarb, propoxur, thiodicarb, thiophanox, triazamate, UC-51717. Pyrethroids: acrinatin, allethrin, alphamethrin, 5-benzyl-3-furylmethyl (E)-(1R)-cis-2,2-dimethyl-3-(2-oxothiolan-3-ylidenemethyl)cyclopropanecarboxylate, bifenthrin, beta-cyfluthrin , cyfluthrin, a-cypermethrin, beta-cypermethrin, bioalethrin, bioalethrin ((S)-cyclopentyl isomer), bioresmethrin, bifenthrin, NCI- 85193, cycloprothrin, cyhalothrin, cytithrin, cyphenothrin, deltamethrin, empentrin, esfenvalerate, etofenprox, fenfluthrin, fenpropathrin , fenvalerate, flucitrinate, flumethrin, fluvalinate (D-isomer), imiprothrin, cyhalothrin, lambda-cyhalothrin, permethrin, phenothrin, pralethrin, pyrethrins (natural products), resmethrin, tetramethrin, transfluthrin, theta-cypermethrin, silafluofen, t-fluvalinate, tefluthrin , tralomethrin, Zeta-cypermethrin.

[0109] Arthropod growth regulators: a) chitin synthesis inhibitors: benzoylureas: chlorfluazuron, diflubenzuron, fluazuron, flucicloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, teflubenzuron, triflumuron, buprofezin, diophenolan, hexithiazox, etoxazole, chlorphentazine; b) ecdysone antagonists: halofenozide, methoxyfenozide, tebufenozide; c) juvenoids: pyriproxyfen, methoprene (including S-methoprene), fenoxycarb; d) lipid biosynthesis inhibitors: spirodiclofen.

[0110] Other antiparasitics: acequinocil, amitraz, AKD-1022, ANS-118, azadirachtin, Bacillus thuringiensis, bensultap, bifenazate, binapacril, bromopropylate, BTG-504, BTG-505, camfeclor, cartap, chlorobenzylate, chlordimeform, chlorfenapyr, chromafenozide , clothianidin, cyromazine, diaclodene, diafenthiuron, DBI-3204, dynactin, dihydroxymethyldihydroxypyrrolidine, dinobuton, dinocap, endosulfan, etiprol, etofenprox, fenazaquin, flumite, MTI-800, fenpyroximate, fluacripyrim, flubenzimine, flubrocitrinate, flufenzine, flufenprox , fluproxifen, halofenprox, hydramethylnon, IKI-220, canemite, NC-196, Neemgard, nidinorterfuran, nitenpyram, SD-35651, WL-108477, pyridaryl, propargite, protrifenbut, pymetrozine, pyridabene, pyrimidifen, NC-1111, R-195 , RH-0345, RH-2485, RYI-210, S-1283, S-1833, SI-8601, silafluofen, silomadine, spinosad, tebufenpyrad, tetradifon, tetranactin, thiacloprid, thiocyclam, thiamethoxam, tolfenpyrad, triazamate, triethoxyspinosin, trinactin , verbutin, vertalec, YI-5301.

[0111] Biological agents: Bacillus thuringiensis ssp aizawai, kurstaki, Bacillus thuringiensis delta endotoxin, baculovirus, entomopathogenic bacteria, viruses and fungi.

[0112] Bactericides: chlortetracycline, oxytetracycline, streptomycin.

[0113] Other biological agents: enrofloxacin, febantel, penetamate, moloxicam, cephalexin, kanamycin, pimobendan, clenbuterol, omeprazole, tiamulin, benazepril, pyriprole, cefquinome, florfenicol, buserelin, cefovecin, tulathromycin, ceftiour, carprofen, metaflumizone, praziquarantel, triclabendazole .

[0114] The following mixtures of the compounds of formula (I) with active ingredients are preferred. The abbreviation “TX” means a compound selected from the group consisting of compounds T-2.01 through T-2.14 through T-66.01 through T-66.14 shown in Tables 2 through 66 (below) or compounds A.1 through A.43 described in Table A (below) or compounds B.1 to B.24 described in Table B (below). an adjuvant selected from the group of substances consisting of petroleum oils (alternative name) (628) + TX, an acaricide selected from the group of substances consisting of 1,1-bis(4-chlorophenyl)-2-ethoxyethanol (IUPAC name) ( 910) + TX, 2,4-dichlorophenyl benzenesulfonate (IUPAC/Chemical Abstracts name) (1059) + TX, 2-fluoro-N-methyl-N-1-naphthylacetamide (IUPAC name) (1295) + TX, 4- chlorophenylphenylsulfone (IUPAC name) (981) + TX, abamectin (1) + TX, acequinocil (3) + TX, acetoprol [CCN] + TX, acrinathrin (9) + TX, aldicarb (16) + TX, aldoxycarb (863) + TX, alpha-cypermethrin (202) + TX, amidition (870) + TX, amidoflumeth [CCN] + TX, amidothioate (872) + TX, amiton (875) + TX, amiton hydrogenoxalate (875) + TX, amitraz (24) + TX, aramite (881) + TX, arsenic oxide (882) + TX, AVI 382 (compound code) + TX, AZ 60541 (compound code) + TX, azinphos-ethyl (44) + TX, azinphos-methyl (45) + TX, azobenzene (IUPAC name) (888) + TX, azocyclotin (46) + TX, nitrogenate (889) + TX, benomyl (62) + TX, benoxaphos (alternative name) [CCN] + TX, benzoximate (71) + TX, benzyl benzoate (IUPAC name) [CCN] + TX, bifenazate (74) + TX, bifenthrin (76) + TX, binapacril (907) + TX, brofenvalerate (alternative name) + TX , bromocyclene (918) + TX, bromophos (920) + TX, bromophos-ethyl (921) + TX, bromopropylate (94) + TX, buprofezin (99) + TX, butocarboxym (103) + TX, butoxycarboxym (104) + TX, butylpyridabene (alternative name) + TX, calcium polysulfide (IUPAC name) (111) + TX, camfeclor (941) + TX, carbanolate (943) + TX, carbaryl (115) + TX, carbofuran (118) + TX , carbofenothion (947) + TX, CGA 50'439 (development code) (125) + TX, quinomethionate (126) + TX, chlorbenside (959) + TX, chlordimeform (964) + TX, chlordimeform hydrochloride (964) + TX, chlorfenapyr (130) + TX, chlorphenethol (968) + TX, chlorophensone (970) + TX, chlorfensulfide (971) + TX, chlorfenvinphos (131) + TX, chlorobenzylate (975) + TX, chloromebuform (977) + TX, chloromethiuron (978) + TX, chloropropylate (983) + TX, chlorpyrifos (145) + TX, chlorpyrifos-methyl (146) + TX, chlorthiophos (994) + TX, cinerin I (696) + TX, cinerin II ( 696) + TX, cinerins (696) + TX, clofentezine (158) + TX, closantel (alternative name) [CCN] + TX, coumafos (174) + TX, crotamiton (alternative name) [CCN] + TX, crotoxiphos ( 1010) + TX, cufraneb (1013) + TX, cyanhoate (1020) + TX, cyflumetofen (CAS Reg. No.: 400882-07-7) + TX, cyhalothrin (196) + TX, cy-hexatin (199) + TX, cypermethrin (201) + TX, DCPM (1032) + TX, DDT (219) + TX, demefion (1037) + TX, demefion-O (1037) + TX, demefion-S (1037) + TX, demeton ( 1038) + TX, demeton-methyl (224) + TX, demeton-O (1038) + TX, demeton-O-methyl (224) + TX, demeton-S (1038) + TX, demeton-S-methyl (224 ) + TX, demeton-S-methylsulfone (1039) + TX, diafenthiuron (226) + TX, dialiphos (1042) + TX, diazinon (227) + TX, dichlofluanide (230) + TX, dichlorvos (236) + TX, dicliphos (alternative name) + TX, dicofol (242) + TX, dicrotophos (243) + TX, dienochlor (1071) + TX, dimefox (1081) + TX, dimethoate (262) + TX, dynactin (alternative name) (653 ) + TX, dinex (1089) + TX, dinex-diclexin (1089) + TX, dinobuton (269) + TX, dinocape (270) + TX, dinocape-4 [CCN] + TX, dinocape-6 [CCN] + TX, dinocton (1090) + TX, dinopenton (1092) + TX, dinosulfon (1097) + TX, dinoterbon (1098) + TX, dioxation (1102) + TX, diphenylsulfone (IUPAC name) (1103) + TX, disulfiram ( alternative name) [CCN] + TX, disulfoton (278) + TX, DNOC (282) + TX, dofenapine (1113) + TX, doramectin (alternative name) [CCN] + TX, endosulfan (294) + TX, endothion ( 1121) + TX, EPN (297) + TX, eprinomectin (alternative name) [CCN] + TX, ethion (309) + TX, ethoate-methyl (1134) + TX, etoxazole (320) + TX, etrymphos (1142) + TX, fenazaflor (1147) + TX, fenazaquin (328) + TX, fenbutatin oxide (330) + TX, phenothiocarb (337) + TX, fenpropathrin (342) + TX, fenpyrad (alternative name) + TX, fenpyroximate ( 345) + TX, fenson (1157) + TX, fentriphanil (1161) + TX, fenvalerate (349) + TX, fipronil (354) + TX, fluacripyrim (360) + TX, fluazuron (1166) + TX, flubenzimine (1167 ) + TX, flucicloxuron (366) + TX, flucitrinate (367) + TX, fluenethyl (1169) + TX, flufenoxuron (370) + TX, flumethrin (372) + TX, fluorbenside (1174) + TX, fluvalinate (1184) + TX, FMC 1137 (development code) (1185) + TX, formetanate (405) + TX, formetanate hydrochloride (405) + TX, formotion (1192) + TX, formparanate (1193) + TX, gamma- HCH ( 430) + TX, gliodin (1205) + TX, halfenprox (424) + TX, heptenophos (432) + TX, hexadecyl cyclopropanecarboxylate (IUPAC/Chemical Abstracts name) (1216) + TX, hexythiazox (441) + TX, iodomethane (IUPAC name) (542) + TX, isocarbophos (alternative name) (473) + TX, O-(methoxyaminothiophosphoryl) isopropyl salicylate (IUPAC name) (473) + TX, ivermectin (alternative name) [CCN] + TX, jasmolin I (696) + TX, jasmolin II (696) + TX, jodfenfos (1248) + TX, lindane (430) + TX, lufenuron (490) + TX, malathion (492) + TX, malonobene (1254) + TX , mecarbam (502) + TX, mephospholane (1261) + TX, messulfen (alternative name) [CCN] + TX, metacriphos (1266) + TX, methamidophos (527) + TX, methythion (529) + TX, methiocarb (530 ) + TX, methomyl (531) + TX, methyl bromide (537) + TX, metholcarb (550) + TX, mevinphos (556) + TX, mexacarbate (1290) + TX, milbemectin (557) + TX, milbemycin oxime (alternative name) [CCN] + TX, mipafox (1293) + TX, monocrotophos (561) + TX, morphothion (1300) + TX, moxidectin (alternative name) [CCN] + TX, nalede (567) + TX, NC -184 (compound code) + TX, NC-512 (compound code) + TX, nifluridide (1309) + TX, nicomycins (alternative name) [CCN] + TX, nitrilacarb (1313) + TX, nitrilacarb complex 1 :1 zinc chloride (1313) + TX, NNI-0101 (compound code) + TX, NNI-0250 (compound code) + TX, omethoate (594) + TX, oxamyl (602) + TX, oxideprophos (1324 ) + TX, oxydisulfoton (1325) + TX, pp'-DDT (219) + TX, parathion (615) + TX, permethrin (626) + TX, petroleum oils (alternative name) (628) + TX, phencaptone ( 1330) + TX, phentoate (631) + TX, phorate (636) + TX, phosalone (637) + TX, phospholane (1338) + TX, phosmet (638) + TX, phosfamidon (639) + TX, phoxim (642 ) + TX, pirimiphos-methyl (652) + TX, polychloroterpenes (traditional name) (1347) + TX, pollinactins (alternative name) (653) + TX, proclonol (1350) + TX, profenofos (662) + TX, promacil (1354) + TX, propargite (671) + TX, propetamphos (673) + TX, propoxur (678) + TX, protidation (1360) + TX, protoate (1362) + TX, pyrethrin I (696) + TX, pyrethrin II (696) + TX, pyrethrins (696) + TX, pyridabene (699) + TX, pyridafenthion (701) + TX, pyrimidifene (706) + TX, pyrimitate (1370) + TX, quinalphos (711) + TX, quinthiophos (1381) + TX, R-1492 (development code) (1382) + TX, RA-17 (development code) (1383) + TX, rotenone (722) + TX, escradane (1389) + TX, sebufos ( alternative name) + TX, selamectin (alternative name) [CCN] + TX, SI-0009 (compound code) + TX, sofamide (1402) + TX, spirodiclofen (738) + TX, spiromesifene (739) + TX, SSI - 121 (development code) (1404) + TX, sulfiram (alternative name) [CCN] + TX, sulfluramide (750) + TX, sulfotepe (753) + TX, sulfur (754) + TX, SZI-121 (code development) (757) + TX, tau-fluvalinate (398) + TX, tebufenpyrad (763) + TX, TEPP (1417) + TX, terbam (alternative name) + TX, tetrachlorvinphos (777) + TX, tetradifon (786 ) + TX, tetranactin (alternative name) (653) + TX, tetrasul (1425) + TX, thiafenox (alternative name) + TX, thiocarboxime (1431) + TX, thiophanox (800) + TX, thiometon (801) + TX , thioquinox (1436) + TX, thuringiensin (alternative name) [CCN] + TX, triamiphos (1441) + TX, triaratene (1443) + TX, triazophos (820) + TX, triazuron (alternative name) + TX, trichlorfon ( 824) + TX, tripenofos (1455) + TX, trinactin (alternative name) (653) + TX, vamidothion (847) + TX, vaniliprole [CCN] and YI-5302 (compound code) + TX, an algaecide selected from group of substances consisting of betoxazine [CCN] + TX, copper dioctanoate (IUPAC name) (170) + TX, copper sulfate (172) + TX, cybutrin [CCN] + TX, diclone (1052) + TX, dichlorophene ( 232) + TX, endotal (295) + TX, fentin (347) + TX, hydrated lime [CCN] + TX, nabam (566) + TX, quinoclamine (714) + TX, quinonamide (1379) + TX, simazine ( 730) + TX, triphenyltin acetate (IUPAC name) (347) and triphenyltin hydroxide (IUPAC name) (347) + TX, an anthelmintic selected from the group of substances consisting of abamectin (1) + TX, crufomate (1011 ) + TX, doramectin (alternative name) [CCN] + TX, emamectin (291) + TX, emamectin benzoate (291) + TX, eprinomectin (alternative name) [CCN] + TX, ivermectin (alternative name) [CCN] + TX, milbemycin oxime (alternative name) [CCN] + TX, moxidectin (alternative name) [CCN] + TX, piperazine [CCN] + TX, selamectin (alternative name) [CCN] + TX, spinosad (737) and thiophanate (1435) + TX, an avicid selected from the group of substances consisting of chloralose (127) + TX, endrin (1122) + TX, fenthion (346) + TX, pyridin-4-amine (IUPAC name) (23) and strychnine (745) + TX, a bactericide selected from the group of substances consisting of 1-hydroxy-1H-pyridine-2-thione (IUPAC name) (1222) + TX, 4-(quinoxalin-2-ylamino)benzenesulfonamide (IUPAC name) (748) + TX, 8-hydroxyquinoline sulfate (446) + TX, bronopol (97) + TX, copper dioctanoate (IUPAC name) (170) + TX, copper hydroxide (IUPAC name) (169) + TX, cresol [CCN] + TX, dichlorophene (232) + TX, dipyrithione (1105) + TX, dodicine (1112) + TX, phenaminosulf (1144) + TX, formaldehyde (404) + TX, hydrargafen (alternative name) [CCN] + TX, kasugamycin (483) + TX, hydrated kasugamycin hydrochloride (483) + TX, nickel bis(dimethyldithiocarbamate) (IUPAC name) (1308) + TX, nitrapyrin (580) + TX, octylinone (590) + TX, oxolinic acid (606) + TX, oxytetracycline (611) + TX, potassium hydroxyquinoline sulfate (446) + TX, probenazole (658) + TX, streptomycin (744) + TX, streptomycin sesquisulfate (744) + TX, tecloftalam (766 ) + TX, and thiomersal (alternative name) [CCN] + TX, a biological agent selected from the group of substances consisting of Adoxophyes orana GV (alternative name) (12) + TX, Agrobacterium radiobacter (alternative name) (13) + TX, Amblyseius spp. (alternative name) (19) + TX, Anagrapha falcifera NPV (alternative name) (28) + TX, Anagrus atomus (alternative name) (29) + TX, Aphelinus abdominalis (alternative name) (33) + TX, Aphidius colemani ( alternative name) (34) + TX, Aphidoletes aphidimyza (alternative name) (35) + TX, Autographa californica NPV (alternative name) (38) + TX, Bacillus firmus (alternative name) (48) + TX, Bacillus sphaericus Neide ( scientific name) (49) + TX, Bacillus thuringiensis Berliner (scientific name) (51) + TX, Bacillus thuringiensis subsp. aizawai (scientific name) (51) + TX, Bacillus thuringiensis subsp. israelensis (scientific name) (51) + TX, Bacillus thuringiensis subsp. japonensis (scientific name) (51) + TX, Bacillus thuringiensis subsp. kurstaki (scientific name) (51) + TX, Bacillus thuringiensis subsp. tenebrionis (scientific name) (51) + TX, Beauveria bassiana (alternative name) (53) + TX, Beauveria brongniartii (alternative name) (54) + TX, Chrysoperla carnea (alternative name) (151) + TX, Cryptolaemus montrouzieri ( alternative name) (178) + TX, Cydia pomonella GV (alternative name) (191) + TX, Dacnusa sibirica (alternative name) (212) + TX, Diglyphus isaea (alternative name) (254) + TX, Encarsia formosa (name scientific) (293) + TX, Eretmocerus eremicus (alternative name) (300) + TX, Helicoverpa zea NPV (alternative name) (431) + TX, Heterorhabditis bacteriophora and H. megidis (alternative name) (433) + TX, Hippodamia convergens (alternative name) (442) + TX, Leptomastix dactylopii (alternative name) (488) + TX, Macrolophus caliginosus (alternative name) (491) + TX, Mamestra brassicae NPV (alternative name) (494) + TX, Metaphycus helvolus (alternative name) (522) + TX, Metarhizium anisopliae var. acridum (scientific name) (523) + TX, Metarhizium anisopliae var. anisopliae (scientific name) (523) + TX, Neodiprion sertifer NPV and N. lecontei NPV (alternative name) (575) + TX, Orius spp. (alias) + TX, Steinernema bibionis (alternative name) (742) + TX, Steinernema carpocapsae (alternative name) (742) + TX, Steinernema feltiae (alternative name) (742) + TX, Steinernema glaseri (alternative name) (742) + TX , Steinernema riobrave (alternative name) (742) + TX, Steinernema riobravis (alternative name) (742) + TX, Steinernema scapterisci (alternative name) (742) + TX, Steinernema spp. (alternative name) (742) + TX, Trichogramma spp. (alternative name) (826) + TX, Typhlodromus occidentalis (alternative name) (844) and Verticillium lecanii (alternative name) (848) + TX, Bacillus subtilis var. amyloliquefaciens Strain FZB24 (available from Novozymes Biologicals Inc., 5400 Corporate Circle, Salem, VA 24153, USA and known by the trade name Taegro®) + TX, a soil sterilant selected from the group of substances consisting of iodomethane (IUPAC name) (542 ) and methyl bromide (537) + TX, a chemosterilant selected from the group of substances consisting of afolate [CCN] + TX, bisazir (alternative name) [CCN] + TX, busulfan (alternative name) [CCN] + TX, diflubenzuron (250) + TX, dimatif (alternative 66/165 name) [CCN] + TX, hemel [CCN] + TX, hempa [CCN] + TX, metepa [CCN] + TX, methiotepa [CCN] + TX, afolate methyl [CCN] + TX, morzide [CCN] + TX, penfluron (alternative name) [CCN] + TX, tepa [CCN] + TX, thiohempa (alternative name) [CCN] + TX, thiotepa (alternative name ) [CCN] + TX, tretamine (alternative name) [CCN] and uredepa (alternative name) [CCN] + TX, an insect pheromone selected from the group of substances consisting of (E)-dec-5-en- acetate 1-yl with (E)-dec-5-en-1-ol (IUPAC name) (222) + TX, (E)-tridec-4-en-1-yl acetate (IUPAC name) (829) + TX, (E)-6-methyl-hept-2-en-4-ol (IUPAC name) (541) + TX, (E,Z)-tetradeca-4,10-dien-1-yl acetate (name IUPAC) (779) + TX, (Z)-dodec-7-en-1-yl acetate (IUPAC name) (285) + TX, (Z)-hexadec-11-enal (IUPAC name) (436) + TX, (Z)-hexadec-11-en-1-yl acetate (IUPAC name) (437) + TX, (Z)-hexadec-13-en-11-en-1-yl acetate (IUPAC name) (438) + TX, (Z)-icos- 13-en-10-one (IUPAC name) (448) + TX, (Z)-tetradec-7-en-1- al (IUPAC name) (782) + TX, (Z)-tetradec-9-en-1-ol (IUPAC name) (783) + TX, (Z)-tetradec-9-en-1-yl acetate (IUPAC name) (784) + TX, (7E,9Z)-dodeca-7,9-dien-1-yl acetate (IUPAC name) (283) + TX, (9Z,11E)-tetradeca-9,11-dien-1-yl acetate (name IUPAC) (780) + TX, (9Z,12E)-tetradeca-9,12-dien-1-yl acetate (IUPAC name) (781) + TX, 14-methyloctadec-1-ene (IUPAC name) (545 ) + TX, 4-methylnonan-5-ol with 4-methylnonan-5-one (IUPAC name) (544) + TX, alpha-multistriatin (alternative name) [CCN] + TX, brevicomine (alternative name) [CCN] + TX, codlelure (alternative name) [CCN] + TX, codlemona (alternative name) (167) + TX, cuelure (alternative name) (179) + TX, disparlure (277) + TX, dodec-8-en acetate -1-yl (IUPAC name) (286) + TX, dodec-9-en-1-yl acetate (IUPAC name) (287) + TX, dodec-8 + TX, 10-dien-1-yl acetate (IUPAC name) (284) + TX, dominicalure (alternative name) [CCN] + TX, ethyl 4-methyloctanoate (IUPAC name) (317) + TX, eugenol (alternative name) [CCN] + TX, frontalin (alternative name) alternate) [CCN] + TX, gossiplure (alternative name) (420) + TX, grandlure (421) + TX, grandlure I (alternative name) (421) + TX, grandlure II (alternative name) (421) + TX, grandlure III (alternative name) (421) + TX, grandlure IV (alternative name) (421) + TX, hexalure [CCN] + TX, ipsdienol (alternative name) [CCN] + TX, ipsenol (alternative name) [CCN] + TX, japonilure (alternative name) (481) + TX, lineatina (alternative name) [CCN] + TX, litlure (alternative name) [CCN] + TX, looplure (alternative name) [CCN] + TX, medlure [CCN ] + TX, megatomoic acid (alternative name) [CCN] + TX, methyleugenol (alternative name) (540) + TX, muscalure (563) + TX, octadeca-2,13-dien-1-yl acetate (IUPAC name ) (588) + TX, octadeca-3,13-dien-1-yl acetate (IUPAC name) (589) + TX, orfralure (alternative name) [CCN] + TX, orictalure (alternative name) (317) + TX, ostramon (alternative name) [CCN] + TX, siglure [CCN] + TX, sordidine (alternative name) (736) + TX, sulcatol (alternative name) [CCN] + TX, tetradec-11-en- acetate 1-ila (IUPAC name) (785) + TX, trimedlure (839) + TX, trimedlure A (alternative name) (839) + TX, trimedlure B1 (alternative name) (839) + TX, trimedlure B2 (alternative name) (839) + TX, trimedlure C (alternative name) (839) and trunc-call (alternative name) [CCN] + TX, an insect repellent selected from the group of substances consisting of 2-(octylthio)ethanol (IUPAC name) (591) + TX, butopyronoxyl (933) + TX, butoxy(polypropylene glycol) (936) + TX, dibutyl adipate (IUPAC name) (1046) + TX, dibutyl phthalate (1047) + TX, dibutyl succinate (name IUPAC) (1048) + TX, diethyltoluamide [CCN] + TX, dimethyl carbate [CCN] + TX, dimethyl phthalate [CCN] + TX, ethylhexanediol (1137) + TX, hexamide [CCN] + TX, methoquin -butyl (1276) + TX, methylneodecanamide [CCN] + TX, oxamate [CCN] and picaridin [CCN] + TX, an insecticide selected from the group of substances consisting of 1-dichloro-1-nitroethane (IUPAC/Chemical Abstracts name) (1058) + TX, 1,1-dichloro-2,2-bis(4-ethylphenyl)ethane (IUPAC name) (1056), + TX, 1,2-dichloropropane (IUPAC/Chemical Abstracts name) (1062) + TX, 1,2-dichloropropane with 1,3-dichloropropene (IUPAC name) (1063) + TX, 1-bromo-2-chloroethane (IUPAC/Chemical Abstracts name) (916) + TX, 2,2,2 acetate -trichloro-1-(3,4-dichlorophenyl)ethyl (IUPAC name) (1451) + TX, 2,2-dichlorovinyl 2-ethylsulfinylethyl methylphosphate (IUPAC name) (1066) + TX, 2-(1) dimethylcarbamate ,3-dithiolan-2-yl)phenyl (IUPAC/Chemical Abstracts name) (1109) + TX, 2-(2-butoxyethoxy)ethyl thiocyanate (IUPAC/Chemical Abstracts name) (935) + TX, 2-methylcarbamate -(4,5-dimethyl-1,3-dioxolan-2- yl)phenyl (IUPAC/Chemical Abstracts name) (1084) + TX, 2-(4-chloro-3,5-xylyloxy)ethanol (IUPAC name) (986) + TX, 2-chlorovinyl diethylphosphate (IUPAC name) (984) + TX, 2-imidazolidone (IUPAC name) (1225) + TX, 2-isovalerylindan-1,3-dione (IUPAC name) (1246) + TX, 2-methyl(prop-2-ynyl)aminophenyl methylcarbamate (IUPAC name) (1284) + TX, 2-thiocyanatoethyl laurate (IUPAC name) (1433) + TX, 3-bromo-1-chloroprop-1 -ene (IUPAC name) (917) + TX, 3-methyl-1-phenylpyrazol-5-yl dimethylcarbamate (IUPAC name) (1283) + TX, 4-methyl(prop-2-ynyl)amino-3 methylcarbamate ,5-xylyl (IUPAC name) (1285) + TX, 5,5-dimethyl-3-oxocyclohex-1-enyl dimethylcarbamate (IUPAC name) (1085) + TX, abamectin (1) + TX, acephate ( 2) + TX, acetamiprid (4) + TX, acetion (alternative name) [CCN] + TX, acetoprol [CCN] + TX, acrinathrin (9) + TX, acrylonitrile (IUPAC name) (861) + TX, alanicarb ( 15) + TX, aldicarb (16) + TX, aldoxycarb (863) + TX, aldrin (864) + TX, allethrin (17) + TX, allosamidine (alternative name) [CCN] + TX, alixicarb (866) + TX , alpha-cypermethrin (202) + TX, alpha-ecdysone (alternative name) [CCN] + TX, aluminum phosphide (640) + TX, amidition (870) + TX, amidothioate (872) + TX, aminocarb (873) + TX, amiton (875) + TX, amiton hydrogenoxalate (875) + TX, amitraz (24) + TX, anabasine (877) + TX, atidathion (883) + TX, AVI 382 (compound code) + TX, AZ 60541 (compound code) + TX, azadirachtin (alternative name) (41) + TX, azamethiphos (42) + TX, azinphos-ethyl (44) + TX, azinphos-methyl (45) + TX, nitrogenate (889) + TX, delta endotoxins from Bacillus thuringiensis (alternative name) (52) + TX, barium hexafluorosilicate (alternative name) [CCN] + TX, barium polysulfide (IUPAC/Chemical Abstracts name) (892) + TX, barthrin [CCN ] + TX, Bayer 22/190 (development code) (893) + TX, Bayer 22408 (development code) (894) + TX, bendiocarb (58) + TX, benfuracarb (60) + TX, bensultape (66) + TX, beta-cyfluthrin (194) + TX, beta-cypermethrin (203) + TX, bifenthrin (76) + TX, bioalethrin (78) + TX, S-cyclopentenyl isomer of bioalethrin (alternative name) (79) + TX , bioethanometrin [CCN] + TX, biopermethrin (908) + TX, bioresmethrin (80) + TX, bis(2-chloroethyl) ether (IUPAC name) (909) + TX, bistrifluron (83) + TX, borax (86 ) + TX, brofenvalerate (alternative name) + TX, bromfenvinphos (914) + TX, bromocyclene (918) + TX, bromo-DDT (alternative name) [CCN] + TX, bromophos (920) + TX, bromophos-ethyl ( 921) + TX, bufencarb (924) + TX, buprofezin (99) + TX, butacarb (926) + TX, butathiofos (927) + TX, butocarboxim (103) + TX, butonate (932) + TX, butoxycarboxym (104 ) + TX, butylpyridabene (alternative name) + TX, cadusafos (109) + TX, calcium arsenate [CCN] + TX, calcium cyanide (444) + TX, calcium polysulfide (IUPAC name) (111) + TX, camfeclor (941) + TX, carbanolate (943) + TX, carbaryl (115) + TX, carbofuran (118) + TX, carbon disulfide (IUPAC/Chemical Abstracts name) (945) + TX, carbon tetrachloride (IUPAC name ) (946) + TX, carbophenothion (947) + TX, carbosulfan (119) + TX, Cartap (123) + TX, Cartap hydrochloride (123) + TX, Cevadine (alternative name) (725) + TX, Chlorbicyclene ( 960) + TX, chlordane (128) + TX, chlordecone (963) + TX, chlordimeform (964) + TX, chlordimeform hydrochloride (964) + TX, chlorethoxyphos (129) + TX, chlorfenapyr (130) + TX, chlorfenvinphos (131) + TX, chlorfluazuron (132) + TX, chlormephos (136) + TX, chloroform [CCN] + TX, chloropicrin (141) + TX, chlorfoxim (989) + TX, chlorprazophos (990) + TX, chlorpyrifos ( 145) + TX, chlorpyrifos-methyl (146) + TX, chlorthiophos (994) + TX, chromafenozide (150) + TX, cinerin I (696) + TX, cinerin II (696) + TX, cinerins (696) + TX , cis-resmethrin (alternative name) + TX, cismethrin (80) + TX, clocitrin (alternative name) + TX, cloetocarb (999) + TX, closantel (alternative name) [CCN] + TX, clothianidin (165) + TX , copper acetoarsenite [CCN] + TX, copper arsenate [CCN] + TX, copper oleate [CCN] + TX, coumafos (174) + TX, coumitoate (1006) + TX, crotamiton (alternative name) [CCN] + TX, crotoxiphos (1010) + TX, crufomate (1011) + TX, cryolite (alternative name) (177) + TX, CS 708 (development code) (1012) + TX, cyanofenphos (1019) + TX, cyanophos ( 184) + TX, cyanthin (1020) + TX, cyclothrin [CCN] + TX, cycloprothrin (188) + TX, cyfluthrin (193) + TX, cyhalothrin (196) + TX, cypermethrin (201) + TX, cyphenothrin (206 ) + TX, cyromazine (209) + TX, cythioate (alternative name) [CCN] + TX, d-limonene (alternative name) [CCN] + TX, d-tetramethrin (alternative name) (788) + TX, DAEP ( 1031) + TX, dazometh (216) + TX, DDT (219) + TX, decarbofuran (1034) + TX, deltamethrin (223) + TX, demefion (1037) + TX, demefion-O (1037) + TX, demefion -S (1037) + TX, demeton (1038) + TX, demeton-methyl (224) + TX, demeton-O (1038) + TX, demeton-O-methyl (224) + TX, demeton-S (1038) + TX, demeton-S-methyl (224) + TX, demeton-S-methylsulfone (1039) + TX, diafenthiuron (226) + TX, dialiphos (1042) + TX, diamidaphos (1044) + TX, diazinon (227) + TX, dicapton (1050) + TX, diclofenthion (1051) + TX, dichlorvos (236) + TX, dicliphos (alternative name) + TX, dicresil (alternative name) [CCN] + TX, dicrotophos (243) + TX, dicyclanil (244) + TX, dieldrin (1070) + TX, diethyl 5-methylpyrazol-3-yl phosphate (IUPAC name) (1076) + TX, diflubenzuron (250) + TX, dilor (alternative name) [CCN] + TX, dimefluthrin [CCN] + TX, dimefox (1081) + TX, dimetan (1085) + TX, dimethoate (262) + TX, dimethrin (1083) + TX, dimethylvinphos (265) + TX, dimethylan (1086) + TX, dinex (1089) + TX, dinex- dilexin (1089) + TX, dinoprop (1093) + TX, dinosam (1094) + TX, dinoseb (1095) + TX, dinotefuran (271) + TX, diofenolan (1099) + TX, dioxabenzofos (1100) + TX, dioxacarb (1101) + TX, dioxation (1102) + TX, disulfoton (278) + TX, diticrophos (1108) + TX, DNOC (282) + TX, doramectin (alternative name) [CCN] + TX, DSP (1115) + TX, ecdysterone (alternative name) [CCN] + TX, EI 1642 (development code) (1118) + TX, emamectin (291) + TX, emamectin benzoate (291) + TX, EMPC (1120) + TX, empenthrin (292) + TX, endosulfan (294) + TX, endothion (1121) + TX, endrin (1122) + TX, EPBP (1123) + TX, EPN (297) + TX, epofenonan (1124) + TX, eprinomectin (alternative name) [CCN] + TX, esfenvalerate (302) + TX, etafos (alternative name) [CCN] + TX, ethiofencarb (308) + TX, ethion (309) + TX, etiprol (310) + TX, ethoate-methyl (1134) + TX, etoprophos (312) + TX, ethyl formate (IUPAC name) [CCN] + TX, ethyl-DDD (alternative name) (1056) + TX , ethylene dibromide (316) + TX, ethylene dichloride (chemical name) (1136) + TX, ethylene oxide [CCN] + TX, etofenprox (319) + TX, etrymphos (1142) + TX, EXD (1143) + TX, famfur (323) + TX, fenamifos (326) + TX, fenazaflor (1147) + TX, fenchlorphos (1148) + TX, fenetacarb (1149) + TX, fenfluthrin (1150) + TX, fenitrothion (335) + TX, fenobucarb (336) + TX, fenoxacrim (1153) + TX, fenoxycarb (340) + TX, fenpyrithrin (1155) + TX, fenpropathrin (342) + TX, fenpyrad (alternative name) + TX, fensulfothion (1158) + TX, fenthion (346) + TX, fenthion-ethyl [CCN] + TX, fenvalerate (349) + TX, fipronil (354) + TX, flonicamide (358) + TX, flubendiamide (CAS. of CAS Reg.: 272451-65-7) + TX, flucofuron (1168) + TX, flucicloxuron (366) + TX, flucitrinate (367) + TX, fluenethyl (1169) + TX, flufenerim [CCN] + TX, flufenoxuron (370) + TX, flufenprox (1171) + TX, flumethrin (372) + TX, fluvalinate (1184) + TX, FMC 1137 (development code) (1185) + TX, fonofos (1191) + TX, formetanate (405 ) + TX, formetanate hydrochloride (405) + TX, formotion (1192) + TX, formparanate (1193) + TX, fosmethylane (1194) + TX, fospirate (1195) + TX, fosthiazate (408) + TX, fosthiethane ( 1196) + TX, furatiocarb (412) + TX, furethrin (1200) + TX, gamma-cyhalothrin (197) + TX, gamma-HCH (430) + TX, guazatine (422) + TX, guazatine acetates (422) + TX, GY-81 (development code) (423) + TX, halfenprox (424) + TX, halofenozide (425) + TX, HCH (430) + TX, HEOD (1070) + TX, heptaclor (1211) + TX, heptenophos (432) + TX, heterophos [CCN] + TX, hexaflumuron (439) + TX, HHDN (864) + TX, hydramethylnon (443) + TX, hydrogen cyanide (444) + TX, hydroprene (445) + TX, hiquincarb (1223) + TX, imidacloprid (458) + TX, imiprotrin (460) + TX, indoxacarb (465) + TX, iodomethane (IUPAC name) (542) + TX, IPSP (1229) + TX, isazophos (1231) + TX, isobenzane (1232) + TX, isocarbophos (alternative name) (473) + TX, isodrine (1235) + TX, isofenphos (1236) + TX, isolane (1237) + TX, isoprocarb (472) + TX, Isopropyl O-(methoxyaminothiophosphoryl)salicylate (IUPAC name) (473) + TX, isoprothiolane (474) + TX, isothioate (1244) + TX, isoxation (480) + TX, ivermectin (alternative name) [CCN] + TX, jasmolin I (696) + TX, jasmolin II (696) + TX, jodfenfos (1248) + TX, juvenile hormone I (alternative name) [CCN] + TX, juvenile hormone II (alternative name) [CCN] + TX , juvenile hormone III (alternative name) [CCN] + TX, quelevane (1249) + TX, quinoprene (484) + TX, lambda-cyhalothrin (198) + TX, lead arsenate [CCN] + TX, lepimectin (CCN) + TX, leptophos (1250) + TX, lindane (430) + TX, lyrimphos (1251) + TX, lufenuron (490) + TX, litidation (1253) + TX, m-cumenyl methylcarbamate (IUPAC name) (1014) + TX, magnesium phosphide (IUPAC name) (640) + TX, malathion (492) + TX, malonobene (1254) + TX, mazidox (1255) + TX, mecarbam (502) + TX, mecarfon (1258) + TX , menazon (1260) + TX, mephospholane (1261) + TX, mercurous chloride (513) + TX, mesulfenphos (1263) + TX, metaflumizone (CCN) + TX, metam (519) + TX, metam-potassium (alternative name ) (519) + TX, methamsodium (519) + TX, methacryphos (1266) + TX, methamidophos (527) + TX, methanesulfonyl fluoride (IUPAC/Chemical Abstracts name) (1268) + TX, methidathion (529 ) + TX, methiocarb (530) + TX, methocrotophos (1273) + TX, methomyl (531) + TX, methoprene (532) + TX, methoquin-butyl (1276) + TX, methotrin (alternative name) (533) + TX, methoxychlor (534) + TX, methoxyfenozide (535) + TX, methyl bromide (537) + TX, methyl isothiocyanate (543) + TX, methylchloroform (alternative name) [CCN] + TX, methylene chloride [CCN ] + TX, metofluthrin [CCN] + TX, metolcarb (550) + TX, methoxadiazone (1288) + TX, mevinfos (556) + TX, mexacarbate (1290) + TX, milbemectin (557) + TX, milbemycin oxime (name alternative) [CCN] + TX, mipafox (1293) + TX, mirex (1294) + TX, monocrotophos (561) + TX, morphothion (1300) + TX, moxidectin (alternative name) [CCN] + TX, naphthalophos (alternative name) alternative) [CCN] + TX, nalede (567) + TX, naphthalene (IUPAC/Chemical Abstracts name) (1303) + TX, NC-170 (development code) (1306) + TX, NC-184 (compound code ) + TX, nicotine (578) + TX, nicotine sulfate (578) + TX, nifluridide (1309) + TX, nitenpyram (579) + TX, nithiazine (1311) + TX, nitrilacarb (1313) + TX, complex nitrilacarb 1:1 zinc chloride (1313) + TX, NNI-0101 (compound code) + TX, NNI-0250 (compound code) + TX, nornicotine (traditional name) (1319) + TX, novaluron (585) + TX, noviflumuron (586) + TX, O-5-dichloro-4-iodophenyl and O-ethyl ethylphosphonothioate (IUPAC name) (1057) + TX, O,O-diethyl and O-4-methyl-2 phosphorothioate -oxo-2H-chromen- 7-yl (IUPAC name) (1074) + TX, O,O-diethyl O-6-methyl-2-propylpyrimidin-4-yl phosphorothioate (IUPAC name) (1075) + TX , O,O,O',O'-tetrapropyl dithiopyrophosphate (IUPAC name) (1424) + TX, oleic acid (IUPAC name) (593) + TX, omethoate (594) + TX, oxamyl (602) + TX, oxidemeton-methyl (609) + TX, oxideprophos (1324) + TX, oxydisulfoton (1325) + TX, pp'-DDT (219) + TX, para-dichlorobenzene [CCN] + TX, parathion (615) + TX, parathion -methyl (616) + TX, penfluron (alternative name) [CCN] + TX, pentachlorophenol (623) + TX, pentachlorophenyl laurate (IUPAC name) (623) + TX, permethrin (626) + TX, petroleum oils ( alternative name) (628) + TX, PH 60-38 (developmental code) (1328) + TX, fencaptone (1330) + TX, phenothrin (630) + TX, phentoate (631) + TX, phorate (636) + TX, phosalone (637) + TX, phospholane (1338) + TX, phosmet (638) + TX, fosnichlor (1339) + TX, phosfamidon (639) + TX, phosphine (IUPAC name) (640) + TX, phoxim ( 642) + TX, phoxim-methyl (1340) + TX, pirimiphos (1344) + TX, pirimicarb (651) + TX, pirimiphos-ethyl (1345) + TX, pirimiphos-methyl (652) + TX, polychlorodicyclopentadiene isomers ( IUPAC name) (1346) + TX, polychloroterpenes (traditional name) (1347) + TX, potassium arsenite [CCN] + TX, potassium thiocyanate [CCN] + TX, pralethrin (655) + TX, pegone I (alternative name ) [CCN] + TX, precono II (alternative name) [CCN] + TX, precono III (alternative name) [CCN] + TX, primidone (1349) + TX, profenofos (662) + TX, profluthrin [CCN] + TX, promacil (1354) + TX, promecarb (1355) + TX, propaphos (1356) + TX, propetamphos (673) + TX, propoxur (678) + TX, protidation (1360) + TX, prothiophos (686) + TX , protoate (1362) + TX, protrifenbut [CCN] + TX, pymetrozine (688) + TX, pyraclophos (689) + TX, pyrazophos (693) + TX, pyresmethrin (1367) + TX, pyrethrin I (696) + TX , pyrethrin II (696) + TX, pyrethrins (696) + TX, pyridabene (699) + TX, pyridalyl (700) + TX, pyridafenthion (701) + TX, pyrimidifen (706) + TX, pyrimitate (1370) + TX , pyriproxyfen (708) + TX, quassia (alternative name) [CCN] + TX, quinalphos (711) + TX, quinalphos-methyl (1376) + TX, quinothion (1380) + TX, quintiophos (1381) + TX, R -1492 (development code) (1382) + TX, rafoxanide (alternative name) [CCN] + TX, resmethrin (719) + TX, rotenone (722) + TX, RU 15525 (development code) (723) + TX , RU 25475 (development code) (1386) + TX, riania (alternative name) (1387) + TX, ryanodina (traditional name) (1387) + TX, sabadila (alternative name) (725) + TX, escradano (1389 ) + TX, sebufos (alternative name) + TX, selamectin (alternative name) [CCN] + TX, SI-0009 (compound code) + TX, SI-0205 (compound code) + TX, SI-0404 (code compound) + TX, SI-0405 (compound code) + TX, silafluofen (728) + TX, SN 72129 (development code) (1397) + TX, sodium arsenite [CCN] + TX, sodium cyanide ( 444) + TX, sodium fluoride (IUPAC/Chemical Abstracts name) (1399) + TX, sodium hexafluorosilicate (1400) + TX, sodium pentachlorophenoxide (623) + TX, sodium selenate (IUPAC name) (1401) + TX, sodium thiocyanate [CCN] + TX, sofamide (1402) + TX, spinosad (737) + TX, spiromesifen (739) + TX, spirotetramat (CCN) + TX, sulcofuron (746) + TX, sulcofuron-sodium ( 746) + TX, sulfluramide (750) + TX, sulfotepe (753) + TX, sulfuryl fluoride (756) + TX, sulprophos (1408) + TX, tar oils (alternative name) (758) + TX, tau- fluvalinate (398) + TX, tazimcarb (1412) + TX, TDE (1414) + TX, tebufenozide (762) + TX, tebufenpyrad (763) + TX, tebupirimphos (764) + TX, teflubenzuron (768) + TX, tefluthrin (769) + TX, temefos (770) + TX, TEPP (1417) + TX, teralethrin (1418) + TX, terbam (alternative name) + TX, terbufos (773) + TX, tetrachloroethane [CCN] + TX, tetrachlorvinphos (777) + TX, tetramethrin (787) + TX, theta-cypermethrin (204) + TX, thiacloprid (791) + TX, thiafenox (alternative name) + TX, thiamethoxam (792) + TX, ticrofos (1428) + TX , thiocarboxime (1431) + TX, thiocyclam (798) + TX, thiocyclam hydrogenoxalate (798) + TX, thiodicarb (799) + TX, thiophanox (800) + TX, thiometon (801) + TX, thionazine (1434) + TX, thiosultap (803) + TX, thiosultap-sodium (803) + TX, thuringiensin (alternative name) [CCN] + TX, tolfenpyrad (809) + TX, tralomethrin (812) + TX, transfluthrin (813) + TX, transpermethrin (1440) + TX, triamiphos (1441) + TX, triazamate (818) + TX, triazophos (820) + TX, triazuron (alternative name) + TX, trichlorfon (824) + TX, trichlormetaphos-3 (alternative name) [CCN] + TX, trichloronat (1452) + TX, tripenofos (1455) + TX, triflumuron (835) + TX, trimetacarb (840) + TX, triprene (1459) + TX, vamidothion (847) + TX, vaniliprole [ CCN] + TX, veratridine (alternative name) (725) + TX, veratrin (alternative name) (725) + TX, XMC (853) + TX, xylylcarb (854) + TX, YI-5302 (compound code) + TX, zeta-cypermethrin (205) + TX, zetamethrin (alternative name) + TX, zinc phosphide (640) + TX, zolaprophos (1469) and ZXI 8901 (development code) (858) + TX, cyantraniliprol [736994- 63-19 + TX, chlorantraniliprole [500008-45-7] + TX, cyenopirafen [560121-52-0] + TX, cyflumetofen [400882-07-7] + TX, pyrifluquinazone [337458-27-2] + TX, spinetoram [187166-401 + 187166-15-0] + TX, spirotetramat [203313-25-1] + TX, sulfoxaflor [946578-00-3] + TX, flufiprol [704886-18-0] + TX, meperfluthrin [ 915288-13-0] + TX, tetramethylfluthrin [84937-88-2] + TX, triflumezopyrim (disclosed in WO 2012/092115) + TX, a molluscicide selected from the group of substances consisting of bis(tributyltin) oxide (name IUPAC) (913) + TX, bromoacetamide [CCN] + TX, calcium arsenate [CCN] + TX, chloretocarb (999) + TX, copper acetoarsenite [CCN] + TX, copper sulfate (172) + TX, fentin (347) + TX, ferric phosphate (IUPAC name) (352) + TX, metaldehyde (518) + TX, methiocarb (530) + TX, niclosamide (576) + TX, niclosamide-olamine (576) + TX, pentachlorophenol ( 623) + TX, sodium pentachlorophenoxide (623) + TX, tazimcarb (1412) + TX, thiodicarb (799) + TX, tributyltin oxide (913) + TX, tripenmorph (1454) + TX, trimetacarb (840) + TX , triphenyltin acetate (IUPAC name) (347) and triphenyltin hydroxide (IUPAC name) (347) + TX, pyriprole [39473071-3] + TX, a nematicide selected from the group of substances consisting of AKD-3088 (compound code ) + TX, 1,2-dibromo-3-chloropropane (IUPAC/Chemical Abstracts name) (1045) + TX, 1,2-dichloropropane (IUPAC/Chemical Abstracts name) (1062) + TX, 1,2-dichloropropane with 1,3-dichloropropene (IUPAC name) (1063) + TX, 1,3-dichloropropene (233) + TX, 1,1-dichlorotetrahydrothiophene 1,1-dioxide (IUPAC/Chemical Abstracts name) (1065) + TX, 3-(4-chlorophenyl)-5-methylrhodanine (IUPAC name) (980) + TX, 5-methyl-6-thioxo-1,3,5-thiadiazinan-3-ylacetic acid (IUPAC name) (1286) + TX, 6-isopentenylaminopurine (alternative name) (210) + TX, abamectin (1) + TX, acetoprol [CCN] + TX, alanicarb (15) + TX, aldicarb (16) + TX, aldoxycarb (863) + TX , AZ 60541 (compound code) + TX, benclotiaz [CCN] + TX, benomyl (62) + TX, butylpyridabene (alternative name) + TX, cadusafos (109) + TX, carbofuran (118) + TX, carbon disulfide (945) + TX, carbosulfan (119) + TX, chloropicrin (141) + TX, chlorpyrifos (145) + TX, chloretocarb (999) + TX, cytokinins (alternative name) (210) + TX, dazomet (216) + TX, DBCP (1045) + TX, DCIP (218) + TX, diamidaphos (1044) + TX, diclofenthion (1051) + TX, dicliphos (alternative name) + TX, dimethoate (262) + TX, doramectin (alternative name) [CCN] + TX, emamectin (291) + TX, emamectin benzoate (291) + TX, eprinomectin (alternative name) [CCN] + TX, etoprophos (312) + TX, ethylene dibromide (316) + TX, fenamiphos (326) + TX, fenpyrad (alternative name) + TX, fensulfothion (1158) + TX, fosthiazate (408) + TX, fosthiethane (1196) + TX, furfural (alternative name) [CCN] + TX, GY-81 ( development code) (423) + TX, heterophos [CCN] + TX, iodomethane (IUPAC name) (542) + TX, isamidophos (1230) + TX, isazophos (1231) + TX, ivermectin (alternative name) [CCN] + TX, kinetin (alternative name) (210) + TX, mecarfon (1258) + TX, metam (519) + TX, metam-potassium (alternative name) (519) + TX, metam-sodium (519) + TX, methyl bromide (537) + TX, methyl isothiocyanate (543) + TX, milbemycin oxime (alternative name) [CCN] + TX, moxidectin (alternative name) [CCN] + TX, composition of Myrothecium verrucaria (alternative name) ( 565) + TX, NC-184 (compound code) + TX, oxamyl (602) + TX, phorate (636) + TX, phosfamidon (639) + TX, phosphocarb [CCN] + TX, sebufos (alternative name) + TX, selamectin (alternative name) [CCN] + TX, spinosad (737) + TX, terbam (alternative name) + TX, terbufos (773) + TX, tetrachlorothiophene (IUPAC/Chemical Abstracts name) (1422) + TX, thiafenox (alternative name) + TX, thionazine (1434) + TX, triazophos (820) + TX, triazuron (alternative name) + TX, xylenols [CCN] + TX, YI-5302 (compound code) and zeatin (alternative name) (210) + TX, fluensulfone [318290-98-1] + TX, a nitrification inhibitor selected from the group of substances consisting of potassium ethylxanthate [CCN] and nitrapyrin (580) + TX, a plant activator selected from the group of substances consisting of acibenzolar (6) + TX, acibenzolar-S-methyl (6) + TX, probenazole (658) and extract of Reynoutria sachalinensis (alternative name) (720) + TX, a rodenticide selected from the group of substances consisting of 2 -isovalerylindan-1,3-dione (IUPAC name) (1246) + TX, 4-(quinoxalin-2-ylamino)benzenesulfonamide (IUPAC name) (748) + TX, alpha-chlorohydrin [CCN] + TX, phosphide aluminum (640) + TX, antu (880) + TX, arsenic oxide (882) + TX, barium carbonate (891) + TX, bistiosemi (912) + TX, brodifacoum (89) + TX, bromadiolone (91) + TX, bromethalin (92) + TX, calcium cyanide (444) + TX, chloralose (127) + TX, chlorophacinone (140) + TX, cholecalciferol (alternative name) (850) + TX, coumaclor (1004) + TX , coumafuril (1005) + TX, coumatetralil (175) + TX, crimidine (1009) + TX, difenacoum (246) + TX, diphethialone (249) + TX, diphacinone (273) + TX, ergocalciferol (301) + TX, flocoumafen (357) + TX, fluoroacetamide (379) + TX, flupropadine (1183) + TX, flupropadine hydrochloride (1183) + TX, gamma-HCH (430) + TX, HCH (430) + TX, hydrogen cyanide ( 444) + TX, iodomethane (IUPAC name) (542) + TX, lindane (430) + TX, magnesium phosphide (IUPAC name) (640) + TX, methyl bromide (537) + TX, norbormide (1318) + TX, fosacetim (1336) + TX, phosphine (IUPAC name) (640) + TX, phosphorus [CCN] + TX, pindone (1341) + TX, potassium arsenite [CCN] + TX, pyrinuron (1371) + TX, sciliroside (1390) + TX, sodium arsenite [CCN] + TX, sodium cyanide (444) + TX, sodium fluoroacetate (735) + TX, strychnine (745) + TX, thallium sulfate [CCN] + TX, warfarin (851) and zinc phosphide (640) + TX, a synergistic agent selected from the group of substances consisting of 2-(2-butoxyethoxy)ethyl piperonylate (IUPAC name) (934) + TX, 5-(1,3 -benzodioxol-5-yl)-3-hexylcyclohex-2-enone (IUPAC name) (903) + TX, farnesol with nerolidol (alternative name) (324) + TX, MB-599 (development code) (498 ) + TX, MGK 264 (development code) (296) + TX, piperonyl butoxide (649) + TX, piprotal (1343) + TX, propyl isomer (1358) + TX, S421 (development code) (724 ) + TX, sesamex (1393) + TX, sesasmolin (1394) and sulfoxide (1406) + TX, an animal repellent selected from the group of substances consisting of anthraquinone (32) + TX, chloralose (127) + TX, naphthenate copper [CCN] + TX, copper oxychloride (171) + TX, diazinon (227) + TX, dicyclopentadiene (chemical name) (1069) + TX, guazatine (422) + TX, guazatine acetates (422) + TX, methiocarb (530) + TX, pyridin-4-amine (IUPAC name) (23) + TX, thiram (804) + TX, trimetacarb (840) + TX, zinc naphthenate [CCN] and ziram (856) + TX, a virucide selected from the group of substances consisting of imannin (alternative name) [CCN] and ribavirin (alternative name) [CCN] + TX, a wound protectant selected from the group of substances consisting of mercuric oxide (512) + TX, octilinone ( 590) and thiophanate-methyl (802) + TX, and biologically active compounds selected from the group consisting of ametoctradine [865318-97-4] + TX, amisulbrom [348635-87-0] + TX, azaconazole [60207-31-0 ] + TX, benzovindiflupyr [1072957-71-1] + TX, bitertanol [70585-363] + TX, bixafen [581809-46-3] + TX, bromuconazole [11625548-2] + TX, coumoxystrobin [850881-70- 8] + TX, cyproconazole [94361-06-5] + TX, difenoconazole [119446-68-3] + TX, diniconazole [83657-24-3] + TX, enoxastrobin [238410-11-2] + TX, epoxiconazole [106325-08-0] + TX, fenbuconazole [11436943-6] + TX, fenpyrazamine [473798-59-3] + TX, fluquinconazole [136426-54-5] + TX, flusilazole [85509-19-9] + TX, flutriafol [76674-21-0] + TX, fluxapiroxad [907204-31-3] + TX, fluopyram [658066-35-4] + TX, phenaminstrobin [366815-39-6] + TX, isofetamide [875915- 78-9] + TX, hexaconazole [79983-714] + TX, imazalil [35554-44-0] + TX, imibenconazole [8659892-7] + TX, ipconazole [125225-28-7] + TX, ipfentrifluconazole [1417782 -08-1] + TX, isotianil [224049-04-1] + TX, mandestrobin [173662-97-0] (can be prepared according to the procedures described in WO 2010/093059) + TX, mefentrifluconazole [1417782- 03-6] + TX, metconazole [12511623-6] + TX, myclobutanil [88671-89-0] + TX, paclobutrazol [76738-62-0] + TX, pefurazoate [101903-30-4] + TX, penflufen [494793-67-8] + TX, penconazole [66246-88-6] + TX, prothioconazole [178928-70-6] + TX, pyrifenox [88283-41-4] + TX, prochloraz [67747-09-5 ] + TX, propiconazole [60207-90-1] + TX, simeconazole [149508-90-7] + TX, tebuconazole [10753496-3] + TX, tetraconazole [112281-77-3] + TX, triadimefon [43121- 43-3] + TX, triadimenol [55219-65-3] + TX, triflumizole [99387-89-0] + TX, triticonazole [131983-72-7] + TX, ancymidol [12771-68-5] + TX , fenarimol [60168-88-9] + TX, nuarimol [63284-71-9] + TX, bupyrimate [41483-43-6] + TX, dimethyrimole [5221-53-4] + TX, ethyrimole [23947-60 -6] + TX, dodemorph [1593-77-7] + TX, fenpropidine [67306-00-7] + TX, fenpropimorph [67564-91-4] + TX, spiroxamine [11813430-8] + TX, tridemorph [ 81412-43-3] + TX, cyprodinil [12155261-2] + TX, mepanipyrim [110235-47-7] + TX, pyrimethanil [53112-28-0] + TX, fenpiclonil [74738-17-3] + TX , fludioxonil [131341-86-1] + TX, fluindapir [1383809-87-7] + TX, benalaxyl [71626-11-4] + TX, furalaxyl [57646-30-7] + TX, metalaxyl [57837-19 -1] + TX, R-metalaxyl [70630-17-0] + TX, ofurace [58810-48-3] + TX, oxadixyl [77732-09-3] + TX, benomyl [17804-35-2] + TX, carbendazim [10605-21-7] + TX, debacarb [62732-91-6] + TX, fuberidazole [3878-19-1] + TX, thiabendazole [148-79-8] + TX, clozolinate [84332- 86-5] + TX, diclozolin [24201-58-9] + TX, iprodione [36734-19-7] + TX, myclozolin [54864-61-8] + TX, procymidone [32809-16-8] + TX , vinclozolin [50471-44-8] + TX, boscalid [188425-85-6] + TX, carboxin [5234-68-4] + TX, fenfuram [24691-80-3] + TX, flutolanil [66332-96 -5] + TX, flutianil [958647-10-4] + TX, mepronil [55814-41-0] + TX, oxycarboxin [5259-88-1] + TX, penthiopyrad [183675-82-3] + TX, thifluzamide [130000-407] + TX, guazatine [108173-90-6] + TX, dodine [2439-10-3] [112-65-2] (free base) + TX, iminoctadine [13516-27-3] + TX, azoxystrobin [131860-33-8] + TX, dimoxystrobin [149961-52-4] + TX, enestroburin {Proc. BCPC, Int. Congr., Glasgow, 2003, 1, 93} + TX, fluoxastrobin [361377-29-9] + TX, kresoxim-methyl [143390-89-0] + TX, metominostrobin [133408-50-1] + TX, trifloxystrobin [141517-21-7] + TX, orisastrobin [248593-16-0] + TX, picoxystrobin [117428-225] + TX, pyraclostrobin [175013-18-0] + TX, pyraoxystrobin [862588-11 -2] + TX, ferbam [14484-64-1] + TX, mancozeb [8018-01-7] + TX, maneb [12427-38-2] + TX, metiram [900642-2] + TX, propineb [ 12071-83-9] + TX, tiram [137-26-8] + TX, zinebe [12122-67-7] + TX, ziram [137-30-4] + TX, capitafol [2425-06-1] + TX, capitan [133-06-2] + TX, diclofluanide [1085-98-9] + TX, fluoroimide [41205-21-4] + TX, folpet [13307-3 ] + TX, tolylfluanide [731-27 -1] + TX, Bordeaux mixture [8011-63-0] + TX, copper hydroxide [20427-59-2] + TX, copper oxychloride [1332-40-7] + TX, copper sulfate [775898- 7] + TX, copper oxide [1317-39-1] + TX, mancobre [5398893-5] + TX, oxina-copper [10380-28-6] + TX, dinocape [131-726] + TX, nitrotal -isopropyl [10552-74-6] + TX, edifenfos [17109-49-8] + TX, iprobenfos [26087-47-8] + TX, isoprothiolane [50512-35-1] + TX, phosdifen [36519-00 -3] + TX, pyrazophos [13457-18-6] + TX, tolclophos-methyl [57018-049] + TX, acibenzolar-S-methyl [135158-54-2] + TX, anilazine [101-05-3 ] + TX, bentiavalicarb [413615-35-7] + TX, blasticidin-S [2079-00-7] + TX, quinomethionate [2439-01-2] + TX, chloroneb [2675-77-6] + TX, chlorothalonil [1897-45-6] + TX, cyflufenamide [180409-60-3] + TX, cymoxanil [57966-957] + TX, diclone [117-80-6] + TX, diclocimet [139920-32-4] + TX, diclomezine [62865-36-5] + TX, dichloran [99-30-9] + TX, diethofencarb [87130-20-9] + TX, dimethomorph [110488-705] + TX, SYP-LI90 (Flumorph ) [211867-47-9] + TX, dithianon [3347-22-6] + TX, etaboxam [162650-77-3] + TX, etridiazole [2593-15-9] + TX, famoxadone [131807-57- 3] + TX, fenamidone [161326-34-7] + TX, fenoxanil [115852-48-7] + TX, fentin [668-34-8] + TX, ferimzone [89269-64-7] + TX, fluazinam [79622-59-6] + TX, fluopicolide [239110-15-7] + TX, flusulfamide [106917-52-6] + TX, fenexamide [126833-17-8] + TX, fosetyl aluminum [39148-24 -8] + TX, himexazole [1000444-1] + TX, iprovalicarb [140923-17-7] + TX, IKF-916 (Ciazofamide) [120116-88-3] + TX, kasugamycin [6980-18-3] + TX, metasulfocarb [66952-49-6] + TX, metrafenone [220899-03-6] + TX, pencycuron [66063-05-6] + TX, phthalide [27355-22-2] + TX, picarbutrazox [500207 -04-5] + TX, polyoxins [11113-80-7] + TX, probenazole [27605-76-1] + TX, propamocarb [25606-41-1] + TX, proquinazide [189278-12-4] + TX, pidiflumetofen [1228284-64-7] + TX, pyramethostrobin [915410-70-7] + TX, pyroquilone [57369-32-1] + TX, pyriofenone [688046-61-9] + TX, piribencarb [799247- 52-2] + TX, Pyrisoxazole [847749-37-5] + TX, Quinoxifene [12449518-7] + TX, Quintozene [82-68-8] + TX, Sulfur [7704-34-9] + TX, Timorex GoldTM (plant extract containing tea tree oil from Stockton Group) + TX, tebufloquine [37664578-2] + TX, tiadinil [223580-51-6] + TX, triazoxide [7245958-6] + TX, tolprocarb [911499 -62-2] + TX, triclopiricarb [902760-40-1] + TX, tricyclazole [41814-78-2] + TX, triporin [26644-46-2] + TX, validamycin [37248-47-8] + TX, valifenalate [283159-90-0] + TX, zoxamide (RH7281) [15605268-5] + TX, mandipropamide [374726-62-2] + TX, isopyrazam [881685-58-1] + TX, fenamacril + TX , sedaxane [874967-67-6] + TX, trinexapac-ethyl [95266-40-3] + TX, (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methane-naphthalen- 3-difluoromethyl-1-methyl-1H-pyrazol-4-carboxylic acid 5-yl)-amide (disclosed in WO 2007/048556) + TX, (3',4',5'-trifluoro-biphenyl-2- yl)-3-difluoromethyl-1-methyl-1H-pyrazol-4-carboxylic acid amide (disclosed in WO 2006/087343) + TX, [(3S,4R,4aR,6S,6aS,12R,12aS,12bS) -3- [(cyclopropylcarbonyl)oxy]-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-6,12-dihydroxy-4,6a,12b-trimethyl- 11-oxo-9-(3-pyridinyl)-2H,11H-naphtho[2,1-b]pyrano[3,4-e]pyran-4-yl]methyl-cyclopropanecarboxylate [915972-17-7] + TX and 1,3,5-trimethyl-N-(2-methyl-1-oxopropyl)-N-[3-(2-methylpropyl)-4-[2,2,2-trifluoro-1-methoxy-1-( trifluoromethyl)ethyl]phenyl]-1H-pyrazol-4-carboxamide [926914-55-8] + TX, or a biologically active compound selected from the group consisting of N-[(5-chloro-2-isopropyl-phenyl)methyl ]- N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-pyrazol-4-carboxamide (can be prepared according to the procedures described in WO 2010/130767) + TX, 2,6- Dimethyl- 1H,5H-[1,4]dithyyne[2,3-c:5,6-c']dipyrrole-1,3,5,7(2H,6H)-tetrone (can be prepared according to the procedures described in WO 2011/138281) + TX, 6-ethyl-5,7-dioxo-pyrrolo[4,5][1,4]dithi-ino[1,2-c]isothiazol-3-carbonitrile + TX, 4-(2-bromo-4-fluoro-phenyl)-N-(2-chloro-6-fluoro-phenyl)-2,5-dimethyl-pyrazol-3-amine (may be prepared according to the procedures described in WO 2012/031061) + TX, 3-(difluoromethyl)-N-(7-fluoro-1,1,3-trimethyl-indan-4-yl)-1-methyl-pyrazol-4-carboxamide (can be prepared from according to the procedures described in WO 2012/084812) + TX, CAS 850881-30-0 + TX, 3-(3,4-dichloro-1,2-thiazol-5-ylmethoxy)-1,1-dioxide ,2-benzothiazole (can be prepared according to the procedures described in WO 2007/129454) + TX, 2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxy-N-methyl -acetamide + TX, 3-(4,4-difluoro-3,4-dihydro-3,3-dimethylisoquinolin-1-yl)quinolone (can be prepared according to the procedures described in WO 2005/070917) + TX, 2-[2-fluoro-6-[(8-fluoro-2-methyl-3-quinolyl)oxy]phenyl]propan-2-ol (can be prepared according to the procedures described in WO 2011/081174) + TX, 2-[2-[(7,8-difluoro-2-methyl-3-quinolyl)oxy]-6-fluoro-phenyl]propan-2-ol (may be prepared according to procedures described in WO 2011/081174) + TX, oxathiapiproline + TX [1003318-67-9], N- [6-[[[(1-methyltetrazol-5-yl)-phenyl-methylene]amino]oxymethyl]-2-pyridyl]carbamate tert-butyl + TX, N-[2-(3,4-difluorophenyl)phenyl]-3-(trifluoromethyl)pyrazine-2-carboxamide (can be prepared according to the procedures described in WO 2007/072999) + TX , 3-(difluoromethyl)-1-methyl-N-[(3R)-1,1,3-trimethylindan-4-yl]pyrazol-4-carboxamide (can be prepared according to the procedures described in WO 2014/013842 ) + TX, 2,2,2-trifluoroethyl N-[2-methyl-1-[[(4-methylbenzoyl)amino]methyl]propyl]carbamate + TX, (2RS)-2-[4-(4- chlorophenoxy)-α,α,α-trifluoro-o-tolyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol + TX, (2RS)-2-[4- (4-chlorophenoxy)-α,α,α-trifluoro-o-tolyl]-3-methyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol + TX, 2- (difluoromethyl)-N-[(3R)-3-ethyl-1,1-dimethyl-indan-4-yl]pyridine-3-carboxamide + TX, 2-(difluoromethyl)-N-[3-ethyl-1, 1-dimethyl-indan-4-yl]pyridine-3-carboxamide + TX, N'-(2,5-dimethyl-4-phenoxy-phenyl)-N-ethyl-N-methyl-formamidine + TX, N'- [4-(4,5-dichlorothiazol-2-yl)oxy-2,5-dimethyl-phenyl]-N-ethyl-N-methyl-formamidine (can be prepared according to the procedures described in WO 2007/031513) + TX, [2-[3- [2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4.5 -dihydroisoxazol-5-yl]-3-chloro-phenyl]methanesulfonate (can be prepared according to the procedures described in WO 2012/025557) + TX, N-[6-[[(Z)-[(1 but-3-ynyl-methyltetrazol-5-yl)-phenyl-methylene]amino]oxymethyl]-2-pyridyl]carbamate (may be prepared according to the procedures described in WO 2010/000841) + TX, 2-[ [3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl]-4H-1,2,4-triazol-3-thione (can be prepared according to the procedures described in WO 2010/146031) + TX, methyl N-[[5-[4-(2,4-dimethylphenyl)triazol-2-yl]-2-methyl-phenyl]methyl]carbamate + TX, 3-chloro- 6-methyl-5-phenyl-4-(2,4,6-trifluorophenyl)pyridazine (can be prepared according to the procedures described in WO 2005/121104) + TX, 2-[2-chloro-4-(4 -chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol (can be prepared according to the procedures described in WO 2013/024082) + TX, 3-chloro-4 -(2,6-difluorophenyl)-6-methyl-5-phenyl-pyridazine (can be prepared according to the procedures described in WO 2012/020774) + TX, 4-(2,6-difluorophenyl)-6-methyl -5-phenyl-pyridazine-3-carbonitrile (can be prepared according to the procedures described in WO 2012/020774) + TX, (R)-3-(difluoromethyl)-1-methyl-N-[1,1, 3-trimethylindan-4-yl]pyrazol-4-carboxamide (can be prepared according to the procedures described in WO 2011/162397) + TX, 3-(difluoromethyl)-N-(7-fluoro-1,1,3 -trimethyl-indan-4-yl)-1-methyl-pyrazol-4-carboxamide (can be prepared according to the procedures described in WO 2012/084812) + TX, 1-[2-[[1-(4- chlorophenyl)pyrazol-3-yl]oxymethyl]-3-methyl-phenyl]-4-methyl-tetrazol-5-one (can be prepared according to the procedures described in WO 2013/162072) + TX, 1-methyl- 4-[3-methyl-2-[[2-methyl-4-(3,4,5-trimethylpyrazol-1-yl)phenoxy]methyl]phenyl]tetrazol-5-one (can be prepared according to procedures described in WO 2014/051165) + TX, (Z,2E)-5-[1-(4-chlorophenyl)pyrazol-3-yl]oxy-2-methoxy-imino-N,3-dimethyl-pent-3- enamide + TX, (4-phenoxyphenyl)methyl 2-amino-6-methyl-pyridine-3-carboxylate + TX, N-(5-chloro-2-isopropylbenzyl)-N-cyclopropyl-3-(difluoromethyl)-5 - fluoro-1-methylpyrazol-4-carboxamide [1255734-28-1] (can be prepared according to the procedures described in WO 2010/130767) + TX, 3-(difluoromethyl)-N-[(R)-2 ,3-dihydro-1,1,3-trimethyl-1H-inden-4-yl]-1-methylpyrazol-4-carboxamide [1352994-67-2] + TX, N'-(2,5-dimethyl -4-phenoxy-phenyl)-N-ethyl-N-methyl-formamidine + TX, N'-[4-(4,5-dichloro-thiazol-2-yloxy)-2,5-dimethyl-phenyl]-N -ethyl-N-methyl-formamidine + TX, N'-(2,5-dimethyl-4-phenoxy-phenyl)-N-ethyl-N-methyl-formamidine + TX, N'-[4-(4,5 -dichloro-thiazol-2-yloxy)-2,5-dimethyl-phenyl]-N-ethyl-N-methyl-formamidine + TX, (fenpicoxamide [517875-34-2]) + TX (as described in WO 2003/035617), 2-(difluoromethyl)-N-(1,1,3-trimethylindan-4-yl)pyridine-3-carboxamide + TX , 2-(difluoromethyl)-N-(3-ethyl-1,1-dimethyl-indan-4-yl)pyridine-3-carboxamide + TX, 2-(difluoromethyl)-N-(1,1-dimethyl-3 - propyl-indan-4-yl)pyridine-3-carboxamide + TX, 2-(difluoromethyl)-N-(3-isobutyl-1,1-dimethyl-indan-4-yl)pyridine-3-carboxamide + TX, 2-(difluoromethyl)-N-[(3R)- 1,1,3-trimethylindan-4-yl)pyridine-3-carboxamide + TX, 2-(difluoromethyl)-N-[(3R)-3-ethyl- 1,1-dimethyl-indan-4-yl]pyridine-3-carboxamide + TX, and 2-(difluoromethyl)-N-[(3R)- 1,1-dimethyl-3-propyl-indan-4-yl] pyridine-3-carboxamide + TX, wherein each of these carboxamide compounds can be prepared according to the procedures described in WO 2014/095675 and/or WO 2016/139189.

[0115] References in square brackets after active ingredients, for example, [3878-19-1] refer to the Chemical Abstracts Registration Number. The mixing partners described above are known. When active ingredients are included in “The Pesticide Manual” [The Pesticide Manual - A World Compendium; Thirteenth Edition; Editor: C. D. S. Tomlin; The British Crop Protection Council], are described therein under the entry number given in parentheses herein above for the particular compound; for example, the compound “abamectin” is described under accession number (1). When “[CCN]” is added here above to the particular compound, the compound in question is included in the “Compendium of Pesticide Common Names”, which can be accessed via the internet [A. Wood; "Compendium of Pesticide Common Names", Trademark © 1995-2004]; for example, the compound “acetoprol” is described at the internet address http://www.alanwood.net/pesticides/acetoprole.html.

[0116] Most of the active ingredients described above are referred to herein above by a so-called “common name”, with the relevant “ISO common name” or another “common name” used in individual cases. If the designation is not a “common name,” the nature of the designation used instead is given in parentheses for the particular compound; in this case the IUPAC name, the IUPAC/Chemical Abstracts name, a “chemical name”, a “traditional name”, a “compound name” or a “development code” is used or, if neither of these designations nor a “common name”, an “alternative name” is used. “No. CAS Reg” designates the Chemical Abstracts Registration Number.

[0117] The mixture of active ingredients of compounds of formula (I) selected from a compound selected from compounds T-2.01 to T-2.14 to T-66.01 to T-66.14 shown in Tables 2 to 66 (below) or compounds A. 1 to A.43 described in Table A (below) or compounds B.1 to B.24 described in Table B (below), preferably in a mixing ratio of from 100:1 to 1:6000, especially from 50:1 to 1:50, more especially in a ratio from 20:1 to 1:20, even more especially from 10:1 to 1:10, most especially between 5:1 and 1:5, with special preference being given to a ratio from 2 :1 to 1:2, and a ratio of from 4:1 to 2:1 being equally preferred, above all in a ratio of 1:1, or 5:1, or 5:2, or 5:3, or 5 :4, or 4:1, or 4:2, or 4:3, or 3:1, or 3:2, or 2:1, or 1:5, or 2:5, or 3:5, or 4 :5, or 1:4, or 2:4, or 3:4, or 1:3, or 2:3, or 1:2, or 1:600, or 1:300, or 1:150, or 1 :35, or 2:35, or 4:35, or 1:75, or 2:75, or 4:75, or 1:6000, or 1:3000, or 1:1500, or 1:350, or 2 :350, or 4:350, or 1:750, or 2:750, or 4:750. These mixing ratios are by weight.

[0118] Mixtures as described above can be used in a method for controlling pests that comprises applying a composition comprising a mixture as described above to the pests or their environment, with the exception of a method for treating the human or animal body by surgery or therapy and diagnostic methods practiced on the human or animal body.

[0119] Mixtures comprising a compound selected from compounds T-2.01 to T-2.14 to T-66.01 to T-66.14 shown in Tables 2 to 66 (below) or compounds A.1 to A.43 described in Table A (below ) or compounds B.1 to B.24 described in Table B (below), and one or more active ingredients as described above may be applied, for example, in a single “ready-mix” form, in a combined spray mixture consisting of separate formulations of the isolated active ingredient components, such as a "tank mix", and in a combined use of the isolated active ingredients when applied in a sequential manner, that is, one after the other within a reasonably short period, such as a few hours or days. The order of application of a compound selected from compounds T-2.01 through T-2.14 through T-66.01 through T-66.14 shown in Tables 2 through 66 (below) or compounds A.1 through A.43 described in Table A (below) or compounds B.1 to B.24 described in Table B (below), and the active ingredient(s) as described above is not essential for the practice of the present invention.

[0120] The compositions according to the invention may also comprise additional solid or liquid auxiliaries, such as stabilizers, for example, non-epoxidized or epoxidized vegetable oils (for example, coconut oil, rapeseed oil or epoxidized soybean oil) , defoamers, e.g. silicone oil, preservatives, viscosity regulators, binders and/or adhesives, fertilizers or other active ingredients to obtain specific effects, e.g. bactericides, fungicides, nematocides, plant activators, molluscicides or herbicides.

[0121] The compositions according to the invention are prepared in a manner known per se, in the absence of auxiliaries, for example, by grinding, screening and/or compressing a solid active ingredient and in the presence of at least one auxiliary, e.g. example, by intimate mixing and/or grinding of the active ingredient with the auxiliary (auxiliary). These processes for preparing the compositions and the use of compounds (I) for preparing these compositions are also a subject of the invention.

[0122] Another aspect of the invention relates to the use of a compound of Formula (I) or a preferred individual compound as defined herein, a composition comprising at least one compound of Formula (I) or at least one preferred individual compound as defined above or of a fungicidal or insecticidal mixture comprising at least one compound of Formula (I) or at least one preferred individual compound as defined above, in admixture with other fungicides or insecticides as described above, for controlling or preventing plant infestation, for example, useful plants such as crop plants, their propagation material, for example, seeds, harvested crops, for example, harvested food crops, or non-living materials, by insects or by phytopathogenic microorganisms, preferably fungal organisms.

[0123] A further aspect of the invention relates to a method for controlling or preventing an infestation of plants, e.g. useful plants such as crop plants, their propagation material, e.g. seeds, harvested crops, e.g. harvested food, or non-living materials, by insects or by phytopathogenic or spoilage-causing microorganisms or organisms potentially harmful to humans, especially fungal organisms, which comprises the application of a compound of Formula (I) or a preferred individual compound such as defined above as an active ingredient in plants, parts of plants or their locus, their propagating material or any part of non-living materials.

[0124] Control or prevention means reducing infestation by phytopathogenic or spoilage-causing microorganisms or organisms potentially harmful to humans, especially fungal organisms, to a level such that an improvement is demonstrated.

[0125] A preferred method for controlling or preventing an infestation of crop plants by phytopathogenic microorganisms, especially fungal organisms, or insects comprising the application of a compound of Formula (I), or an agrochemical composition containing at least one of said compounds, is foliar application. The frequency of application and the rate of application will depend on the risk of infestation by the corresponding pathogen or insect. However, the compounds of Formula (I) can also penetrate the plant through the roots via the soil (systemic action), by drenching the plant locus with a liquid Formulation, or by applying the compounds in solid form to the soil, by example, in granular form (soil application). In irrigated rice crops, such granules can be applied to the irrigated rice field. The compounds of Formula (I) can also be applied to seeds (coating) by impregnating the seeds or tubers with a liquid formulation of the fungicide or by coating them with a solid formulation.

[0126] A formulation, for example, a composition containing the compound of Formula (I) and, if desired, a solid or liquid adjuvant or monomers for encapsulating the compound of Formula (I), can be prepared in a known manner, typically by intimate mixing and/or grinding the compound with diluents, for example, solvents, solid carriers and, optionally, surface-active compounds (surfactants).

[0127] Advantageous application rates are normally 5 g to 2 kg of active ingredient (a.i.) per hectare (ha), preferably 10 g to 1 kg a.i./ha, more preferably 20 g to 600 g a.i./ha. When used as a seed soaking agent, convenient dosages are 10 mg to 1 g of active substance per kg of seeds.

[0128] When the combinations of the present invention are used to treat seeds, rates of 0.001 to 50 g of a compound of Formula (I) per kg of seed, preferably 0.01 to 10 g per kg of seed, are generally sufficient .

[0129] Suitably, a composition comprising a compound of Formula (I) according to the present invention is applied preventively, meaning before the development of disease, or curatively, meaning after development of disease.

[0130] The compositions of the invention can be employed in any conventional form, for example, in the form of a double package, a dry seed treatment powder (DS), a seed treatment emulsion (ES), a concentrate suitable for flowing seed treatment (FS), a seed treatment solution (LS), a water-dispersible seed treatment powder (WS), a seed treatment capsule suspension (CF), a seed treatment gel seeds (GF), an emulsion concentrate (EC), a suspension concentrate (SC), a suspoemulsion (SE), a capsule suspension (CS), a water dispersible granule (WG), an emulsifiable granule (EG) , an emulsion, water in oil (EO), an emulsion, oil in water (EW), a microemulsion (ME), an oil dispersion (OD), an oil miscible fluid (OF), an oil miscible liquid ( OL), a soluble concentrate (SL), an ultra-low volume suspension (SU), an ultra-low volume liquid (UL), a technical concentrate (TK), a dispersible concentrate (DC), a wettable powder (WP) or any technically feasible formulation in combination with agriculturally acceptable adjuvants.

[0131] Such compositions can be produced in a conventional manner, for example, by mixing the active ingredients with appropriate formulation fillers (diluents, solvents, fillers and, optionally, other formulation ingredients such as surfactants, biocides, antifreezes, adherents , thickeners and compounds that provide adjuvant effects). Conventional slow-release formulations may also be employed when long-lasting efficacy is desired. In particular, Formulations to be applied in spray forms, such as water-dispersible concentrates (e.g., EC, SC, DC, OD, SE, EW, EO and the like), wettable powders and granules, may contain surfactants such as wetting agents and dispersants and other compounds that provide adjuvant effects, for example, the condensation product of formaldehyde with naphthalene sulfonate, an alkylarylsulfonate, a lignin sulfonate, a fatty alkyl sulfate, and ethoxylated alkylphenol and an ethoxylated fatty alcohol.

[0132] A seed treatment formulation is applied in a manner known per se to the seeds employing the combination of the invention and a diluent in the form of a suitable seed treatment formulation, for example, as an aqueous suspension or in a powder form. dry, having good adhesion to the seeds. Such seed treatment formulations are known in the art. Seed treatment formulations may contain isolated active ingredients or a combination of active ingredients in encapsulated form, for example, as slow-release capsules or microcapsules.

[0133] In general, formulations include from 0.01 to 90% by weight of active agent, from 0 to 20% of agriculturally acceptable surfactant and 10 to 99.99% of solid or liquid formulation inert agents and adjuvant(s). ), wherein the active agent consists of at least the compound of Formula (I) optionally together with other active agents, particularly microbiicides or preservatives or the like. Concentrated forms of the compositions generally contain between about 2 and 80%, preferably between about 5 and 70% by weight, of active agent. Application forms of the formulation may contain, for example, from 0.01 to 20% by weight, preferably from 0.01 to 5% by weight of the active agent. Although commercial products are preferably formulated as concentrates, the end user will typically use diluted formulations.

[0134] Although it is preferred to formulate commercial products as concentrates, the end user will typically use diluted formulations.

[0135] Table 1 (below) reveals 14 combinations of substituents R1, R2, R3, R4, R5 and R6 according to compounds as defined for Formula (T-1). Formula (T-1) corresponds to formula (I) as defined for the present invention.

[0136] Each of Tables 2 through 66 (which follow Table 1) provides 14 individual compounds of formula (T-1) in which Z is as specifically defined in Tables 2 through 66 (Formulas T-2 through T-66 ), which refer to Table 1 in which R1, R2, R3, R4, R5 and R6 are specifically defined. Table 1: Table 2: This table reveals compounds T-2.01 to T- 2.14 of formula (T-2), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 3: This table reveals compounds T-3.01 to T- 3.14 of formula (T-3), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 4: This table reveals compounds T-4.01 to T-4.14 of formula (T-4), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 5: This table reveals compounds T-5.01 to T-5.14 of formula (T-5), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 6: This table reveals compounds T-6.01 to T-6.14 of formula (T-6), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 7: This table reveals compounds T-7.01 to T-7.14 of formula (T-7), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 8: This table reveals compounds T-8.01 to T-8.14 of formula (T-8), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 9: This table reveals compounds T-9.01 to T- 9.14 of formula (T-9), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 10: This table reveals compounds T-10.01 to T-10.14 of formula (T-10), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 11: This table reveals compounds T-11.01 to T-11.14 of formula (T-11), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 12: This table reveals compounds T-12.01 to T-12.14 of formula (T-12), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 13: This table reveals compounds T-13.01 to T-13.14 of formula (T-13), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 14: This table reveals compounds T-14.01 to T-14.14 of formula (T-14), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 15: This table reveals compounds T-15.01 to T-15.14 of formula (T-15), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 16: This table reveals compounds T-16.01 to T-16.14 of formula (T-16), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 17: This table reveals compounds T-17.01 to T-17.14 of formula (T-17), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 18: This table reveals compounds T-18.01 to T-18.14 of formula (T-18), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 19: This table reveals compounds T-19.01 to T-19.14 of formula (T-19), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 20: This table reveals compounds T-20.01 to T-20.14 of formula (T-20), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 21: This table reveals compounds T-21.01 to T-21.14 of formula (T-21), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 22: This table reveals compounds T-22.01 to T-22.14 of formula (T-22), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 23: This table reveals compounds T-23.01 to T-23.14 of formula (T-23), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 24: This table reveals compounds T-24.01 to T-24.14 of formula (T-24), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 25: This table reveals compounds T-25.01 to T-25.14 of formula (T-25), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 26: This table reveals compounds T-26.01 to T-26.14 of formula (T-26), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 27: This table reveals compounds T-27.01 to T-27.14 of formula (T-27), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 28: This table reveals compounds T-28.01 to T-28.14 of formula (T-28), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 29: This table reveals compounds T-29.01 to T-29.14 of formula (T-29), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 30: This table reveals compounds T-30.01 to T-30.14 of formula (T-30), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 31: This table reveals compounds T-31.01 to T-31.14 of formula (T-31), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 32: This table reveals compounds T-32.01 to T-32.14 of formula (T-32), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 33: This table reveals compounds T-33.01 to T-33.14 of formula (T-33), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 34: This table reveals compounds T-34.01 to T-34.14 of formula (T-34), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 35: This table reveals compounds T-35.01 to T-35.14 of formula (T-35), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 36: This table reveals compounds T-36.01 to T-36.14 of formula (T-36), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 37: This table reveals compounds T-37.01 to T-37.14 of formula (T-37), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 38: This table reveals compounds T-38.01 to T-38.14 of formula (T-38), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 39: This table reveals compounds T-39.01 to T-39.14 of formula (T-39), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 40: This table reveals compounds T-40.01 to T-40.14 of formula (T-40), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 41: This table reveals compounds T-41.01 to T-41.14 of formula (T-41), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 42: This table reveals compounds T-42.01 to T-42.14 of formula (T-42), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 43: This table reveals compounds T-43.01 to T-43.14 of formula (T-43), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 44: This table reveals compounds T-44.01 to T-44.14 of formula (T-44), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 45: This table reveals compounds T-45.01 to T-45.14 of formula (T-45), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 46: This table reveals compounds T-46.01 to T-46.14 of formula (T-46), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 47: This table reveals compounds T-47.01 to T-47.14 of formula (T-47), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 48: This table reveals compounds T-48.01 to T-48.14 of formula (T-48), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 49: This table reveals compounds T-49.01 to T-49.14 of formula (T-49), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 50: This table reveals compounds T-50.01 to T-50.14 of formula (T-50), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 51: This table reveals compounds T-51.01 to T-51.14 of formula (T-51), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 52: This table reveals compounds T-52.01 to T-52.14 of formula (T-52), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 53: This table reveals compounds T-53.01 to T-53.14 of formula (T-53), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings shown in Table 1. Table 54: This table reveals compounds T-54.01 to T-54.14 of formula (T-54), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 55: This table reveals compounds T-55.01 to T-55.14 of formula (T-55), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 56: This table reveals compounds T-56.01 to T-56.14 of formula (T-56), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 57: This table reveals compounds T-57.01 to T-57.14 of formula (T-57), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 58: This table reveals compounds T-58.01 to T-58.14 of formula (T-58), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 59: This table reveals compounds T-59.01 to T-59.14 of formula (T-59), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 60: This table reveals compounds T-60.01 to T-60.14 of formula (T-60), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 61: This table reveals compounds T-61.01 to T-61.14 of formula (T-61), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 62: This table reveals compounds T-62.01 to T-62.14 of formula (T-62), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 63: This table reveals compounds T-63.01 to T-63.14 of formula (T-63), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 64: This table reveals compounds T-64.01 to T-64.14 of formula (T-64), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 65: This table reveals compounds T-65.01 to T-65.14 of formula (T-65), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1. Table 66: This table reveals compounds T-66.01 to T-66.14 of formula (T-66), which is a compound of formula (I) in which R1, R2, R3, R4, R5 and R6 have the specific meanings given in Table 1.

[0137] According to the specific compounds of formulas (T-2) to (T-66) according to the invention as described above in Tables 2 to 66 where Z is Z1, analogous compounds where Z is Z2 are also described.

EXAMPLES

[0138] The following Examples serve to illustrate the invention.

[0139] The compounds of the invention can be distinguished from known compounds by virtue of greater effectiveness at low application rates, which can be verified by the person skilled in the art using the experimental procedures outlined in the Examples, using lower application rates if necessary , for example, 50 ppm, 12.5 ppm, 6 ppm, 3 ppm, 1.5 ppm, 0.8 ppm or 0.2 ppm.

[0140] The compounds of Formula (I) may possess any number of benefits including, inter alia, advantageous levels of biological activity to protect plants against diseases that are caused by fungi or superior properties for use as agrochemical active ingredients (e.g., greater biological activity, an advantageous spectrum of activity, an increased safety profile (including improved crop tolerance), improved physicochemical properties or increased biodegradability).

[0141] Throughout this description, temperatures are presented in degrees Celsius (°C) and “pf.” means melting point. LC/MS means Liquid Chromatography-Mass Spectrometry and the description of the devices and the method (Methods A, B and C) is as follows:

The description of the LC/MS device and method A is:

[0142] Spectra were recorded on a Waters Mass Spectrometer (SQD, SQDII Single Quadrupole Mass Spectrometer) equipped with an electrospray source (Polarity: positive and negative ions), Capillary: 3.00 kV, Cone Range : 30 V, Extractor: 2.00 V, Source Temperature: 150 °C, Desolvation Temperature: 350 °C, Cone Gas Flow: 50 L/h, Desolvation Gas Flow: 650 L/h, Range masses: 100 to 900 Da) and a Waters Acquity UPLC: Binary pump, heated column compartment, diode array detector and ELSD detector. Column: Waters UPLC HSS T3, 1.8 μ m, 30 x 2.1 mm, Temp: 60 °C; DAD wavelength range (nm): 210 to 500, Solvent Gradient: A = water + MeOH 5% + HCOOH 0.05%, B= Acetonitrile + HCOOH 0.05%, gradient: 10100% B in 1.2 min; Flow (mL/min) 0.85

The description of the LC/MS apparatus and method B is:

[0143] The spectra were recorded on a Waters Mass Spectrometer (UPLC ACQUITY) (single quadrupole mass spectrometer SQD, SQDII) equipped with an electrospray source (Polarity: positive or negative ions, Capillary: 3.0 kV, Cone: 30V, Extractor: 3.00 V, Source Temperature: 150 °C, Desolvation Temperature: 400 °C, Cone Gas Flow: 60 L/hr, Desolvation Gas Flow: 700 L/hr, Range mass range: 140 to 800 Da), DAD wavelength range (nm): 210 to 400 and a Waters Acquity UPLC: Solvent degasser, binary pump, heated column compartment and diode array detector. Column: Waters UPLC HSS T3, 1.8 μm, 30 x 2.1 mm, Temp: 60 °C; DAD wavelength range (nm): 210 to 500, Solvent Gradient: A = Water/Methanol 9:1, 0.1% formic acid, B = Acetonitrile + 0.1% formic acid, gradient: 0100% from B in 2.5 min; Flow (mL/min) 0.75 The description of the LC/MS apparatus and method C is: Waters SQ 2 Detector Ionization method: Electrospray Polarity: positive ions Capillary (kV) 3.5, Cone (V) 30 .00, Extractor (V) 3.00, Source Temperature (°C) 150, Desolvation Temperature (°C) 400, Cone Gas Flow (L/h) 60, Desolvation Gas Flow (L/h ) 700 Mass Range: 140 to 800 DAD Wavelength Range (nm): 210 to 400 Waters ACQUITY UPLC Method with the following HPLC gradient conditions (Solvent A: Water/Methanol 9:1, formic acid 0.1% and Solvent B: Acetonitrile, 0.1% formic acid)

[0144] Column type: Waters UPLC ACQUITY HSS T3; Column length: 30 mm; Column inner diameter: 2.1 mm; Particle Size: 1.8 microns; Temperature: 60°C.

[0145] When necessary, enantiomerically pure final compounds can be obtained from racemic materials as appropriate through standard physical separation techniques, such as chiral reversed-phase chromatography, or through stereoselective synthetic techniques, for example, using chiral departure.

[0146] The active ingredient is extensively mixed with the adjuvants and the mixture is extensively crushed in a suitable mill, yielding wettable powders that can be diluted with water to yield suspensions with the desired concentration.

[0147] The active ingredient is extensively mixed with the adjuvants, and the mixture is extensively crushed in a suitable mill, resulting in powders that can be used directly for seed treatment.

[0148] Emulsions of any required dilution, which can be used to protect plants, can be obtained from this concentrate by dilution with water.

[0149] Ready-to-use powders are obtained by mixing the active ingredient with the carrier and grinding the mixture in a suitable mill. Such powders can also be used for dry seed films.

[0150] The active ingredient is mixed and crushed with the adjuvants and the mixture is moistened with water. The mixture is extruded and then dried in a stream of air.

[0151] The active ingredient is evenly applied, moistened with polyethylene glycol. dust-free coated granules Finely crushed suspension concentrate is mixed in kaolin. Dust-free coated granules are obtained in this way. Suspension concentrate

[0152] The finely crushed active ingredient is intimately mixed with the adjuvants, creating a suspension concentrate from which suspensions of any desired dilution can be obtained by dilution with water. Using such dilutions, live plants as well as plant propagation material can be treated and protected against infestation by microorganisms by spraying, pouring or immersing.

[0153] The finely crushed active ingredient is intimately mixed with the adjuvants, creating a suspension concentrate from which suspensions of any desired dilution can be obtained by dilution with water. Using such dilutions, live plants as well as plant propagation material can be treated and protected against infestation by microorganisms by spraying, pouring or immersing.

Suspension for Slow Release Capsules

[0154] 28 parts of a combination of the compound of Formula I are mixed with 2 parts of an aromatic solvent and 7 parts of toluene diisocyanate/polymethylene-polyphenylisocyanate mixture (8:1). This mixture is emulsified in a mixture of 1.2 parts polyvinyl alcohol, 0.05 parts of a defoamer and 51.6 parts water until the desired particle size is achieved. To this emulsion is added a mixture of 2.8 parts 1,6-diaminohexane in 5.3 parts water. The mixture is stirred until the polymerization reaction is complete.

[0155] The capsule suspension obtained is stabilized by adding 0.25 parts of a thickener and 3 parts of a dispersing agent. The Capsule Suspension Formulation contains 28% active ingredients. The average diameter of the capsules is 8-15 microns.

[0156] The resulting formulation is applied to seeds as an aqueous suspension in an apparatus suitable for this purpose. List of Abbreviations: AIBN = azobisisobutyronitrile DMF = dimethylformamide DIBAL-H = diisobutylaluminum hydride DIPEA = N,N-diisopropylethylamine EtOAc = ethyl acetate HCl = hydrochloric acid pf = melting point °C = degrees Celsius MeOH = alcohol of methyl NaOH = sodium hydroxide NBS = N-bromosuccinimide min = minutes TA = room temperature h = hour(s) TFAA = trifluoroacetic acid anhydride Preparation Examples Example 1: This example illustrates the preparation of N-propyl-2- [ [4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]tetrazol-5-carboxamide (Compound A.38 of Table A) Step 1: Preparation of 2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]-tetrazol-5-carboxylic acid N-propyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]-methyl]tetrazol-5-carboxamide (Example 2; 3.57 g; purity of 55%) was dissolved in ethanol (9.3 mL) and aqueous sodium hydroxide (1 mol/L; 9.3 mL) was added. The mixture was stirred at room temperature for 90 minutes. Then the ethanol was evaporated and the mixture was acidified with aqueous hydrochloric acid (1N). The aqueous layer was extracted three times with ethyl acetate. The combined organic layers were washed with brine, dried over anhydrous magnesium sulfate, filtered and concentrated. The residue was purified by silica gel chromatography, using a cyclohexane/ethyl acetate gradient as eluent. Thus, the pure title compound was obtained as a white solid (0.73 g, 40% yield). LC/MS (Method A) retention time = 0.84 minutes, 341 (M+H). 1H NMR (400 MHz, CD3OD) δ ppm: 8.16 (d, 2H), 7.62 (d, 2H), 6.07 (s, 2H). 19F NMR (400 MHz, CD3OD) δ ppm: -67.36 (s). Step 2: Preparation of N-propyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]-methyl]tetrazol-5-carboxamide A solution of acid 2 -[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]-tetrazol-5-carboxylic acid (57.3 mg) in dichloromethane (1.7 mL) were added 1-hydroxybenzotriazole (27 mg), 3-(ethyliminomethyleneamino)-N,N-dimethyl-propan-1-amine hydrochloride (39 mg), propan-1-amine (12 mg) and triethylamine (43 mg) at room temperature , then the mixture was stirred at room temperature for 24 hours. The solvent was evaporated and the residue was purified by silica gel chromatography, using a cyclohexane/ethyl acetate gradient as eluent, giving the title compound (40 mg, 63% yield) as a white solid. . LC/MS (Method A) retention time = 1.03 minutes, 382 (M+H). 1H NMR (400 MHz, CDCl3) δ ppm: 8.15 (d, 2H), 7.58 (d, 2H), 7.12 (s, broad, 1H), 5.90 (s, 2H), 3 .49 (q, 2H), 1.67 (m, 2H), 1.00 (t, 3H). 19F NMR (400 MHz, CDCl3) δ ppm: -65.33 (s). Example 2: This example illustrates the preparation of ethyl 2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]tetrazol-5-carboxylate (Compound B.23 of Table B) and ethyl 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]tetrazol-5-carboxylate (Compound B.24 of Table B ) A solution of 3-[4-(bromomethyl)phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole (CAS 2093101-98-3; 3.50 g) in acetonitrile (45.6 mL) was Ethyl 2H-tetrazol-5-carboxylate (1.94 g) was added followed by potassium carbonate (2.36 g). The suspension was heated to 70°C for 3 h. Then the solids were removed by filtration, washed with ethyl acetate and dichloromethane. The mother liquors were evaporated and the residue was purified by silica gel chromatography using a cyclohexane/ethyl acetate gradient to give 2-[[4-[5-(trifluoromethyl)-1,2,4- Ethyl oxadiazol-3-yl]phenyl]methyl]tetrazol-5-carboxylate (1.30 g, 31% yield) as a solid, mp = 122 - 132 °C, LC/MS (Method A) time retention = 1.07 minutes, 369 (M+H). 1H NMR (400 MHz, CDCl3) δ ppm: 8.10 (d, 2H), 7.50 (d, 2H), 6.00 (s, 2H), 4.50 (q, 2H), 1.42 (t, 3H). and ethyl 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]tetrazol-5-carboxylate (1.53 g, 36% yield) in the form of a solid, mp = 125 - 135 °C, LC/MS (Method A) retention time = 1.08 minutes, 369 (M+H). 1H NMR (400 MHz, CDCl3) δ ppm: 8.17 (d, 2H), 7.58 (d, 2H), 5.95 (s, 2H), 4.53 (q, 2H), 1.47 (t, 3H). Example 3: This example illustrates the preparation of the compounds

[0157] A stock solution of 2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]-tetrazol-5-carboxylic acid (600 mg) was prepared in N,N-dimethylacetamide (9.6 mL). This solution (48 times 0.2 mL) was distributed in a deep well plate containing 48 HN(Ra)Rb amines (each 2 equivalents), with dissolution in N,N-dimethylacetamide (48 times 0.3 mL). Then N-ethyl-N-(1-methylethyl)-2-propanamine (3 equivalents) is added to each position of the plate, followed by a solution of O-(7-azabenzotriazol-1-yl)-N,N hexafluorophosphate. ,N',N'-tetramethyluronium (1.2 equivalents) in N,N-dimethylacetamide (48 times 0.3 mL). The plate was sealed and the reaction mixtures were stirred at room temperature for 24 hours. Then the solvent was evaporated and each of the crude products was purified by reverse phase preparative HPLC. Thus, the compounds of Table A were obtained (0.6 to 8 mg each) in pure form. Example 4: This example illustrates the preparation of the compounds in Table B by parallel synthesis.

[0158] A stock solution of 2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]-tetrazol-5-carboxylic acid (24 times 0.04 mmol) was prepared in 24 portions of DMF (each 0.3 mL) in a deep-well plate. Then a stock solution of O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate (24 times 1.7 equivalents) and 2,3,4,6,7,8, 9,10-octahydropyrimido[1,2-a]azepine (24 times 3.35 equivalents) was prepared in 24 portions of N,N-dimethylformamide (each 0.3 mL) and distributed in each position of the plate and stirred for 30 minutes at room temperature. Then 24 HORd alcohols (each between 8 and 40 equivalents) were distributed at each position, the plate was sealed and the reaction mixtures were stirred at room temperature for 24 hours. Then the solvent was evaporated and each of the crude products was purified by reverse phase preparative HPLC. Thus, the compounds of Table B were obtained (1 to 4 mg each) in pure form. Example 5: This example illustrates the preparation of N-(2-methoxyethyl)-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]tetrazol-5- carboxamide (Compound A.39 of Table A).

[0159] To a solution of ethyl 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]tetrazol-5-carboxylate (100 mg) in ethanol ( 2.2 mL) 2-methoxyethylamine (206 mg) was added, then the resulting solution was heated to 70 °C for 18 hours. The resulting suspension was cooled to room temperature, filtered and the filter cake dried, giving N-(2-methoxyethyl)-1-[[4-[5-(trifluoromethyl)-1,2,4- oxadiazol-3-yl]phenyl]methyl]tetrazol-5-carboxamide (54 mg, 50%) as a white solid, mp = 140 - 142 °C. LC/MS (Method A) retention time = 0.97 minutes, 398 (M+H). 1H NMR (400 MHz, CDCl3) δ ppm: 8.16 (d, 2H), 7.59 (d, 2H), 7.44 (s, broad, 1H), 5.92 (s, 2H), 3 .72 (m, 2H), 3.58 (m, 2H), 3.40 (s, 3H). 19F NMR (400 MHz, CDCl3) δ ppm: -65.34 (s). Table A: Melting point (pf) and/or LC/MS (retention time (ÜR)) data for compounds of Formula (I): Table B: Melting point (pf) and/or LC/MS (retention time (ÜR)) data for compounds of Formula (I): BIOLOGICAL EXAMPLES General examples of well plate leaf disc testing: Leaf discs or leaf segments of various plant species are cut from plants grown in a greenhouse. The cut leaf discs or segments are placed in multi-well plates (24-well format) on water agar. Leaf discs are sprayed with a test solution before (preventive) or after (curative) inoculation. Compounds to be tested are prepared as solutions in DMSO (max. 10 mg/mL) which are diluted to the appropriate concentration with 0.025% Tween20 immediately before spraying. The inoculated leaf discs or segments are incubated under defined conditions (temperature, relative humidity, light, etc.), according to the respective test system. A single disease level assessment is performed 3 to 14 days after inoculation, depending on the pathosystem. The percentage of disease control relative to untreated control leaf discs or segments is then calculated. General examples of liquid culture tests in well plates: Mycelial fragments or conidial suspensions of a fungus, freshly prepared from liquid cultures of the fungus or from cryogenic storage, are directly mixed into nutrient broth. DMSO solutions of the test compound (max. 10 mg/mL) are diluted with 0.025% Tween20 by a factor of 50 and 10 μL of this solution is pipetted into a microtiter plate (96-well format). The nutrient broth containing the fungal spore/mycelium fragments is then added to generate a final concentration of the tested compound. Test plates are incubated in the dark at 24°C and 96% relative humidity. Inhibition of fungal growth is determined photometrically after 2 to 7 days, depending on the pathosystem, and the percentage of antifungal activity relative to the untreated control is calculated.

Example 1: Fungicidal activity against Puccinia recondita f. sp. tritici / wheat / preventive on leaf discs (Brown Rust)

[0160] Leaf segments of wheat cv. Kanzler were placed on agar in multi-well plates (24-well format) and sprayed with the formulated test compound diluted in water. Leaf discs were inoculated with a suspension of fungal spores 1 day after application. The inoculated leaf segments were incubated at 19 oC and 75% relative humidity (rH) under a light regime of 12 hours of light/12 hours of darkness in a climate-controlled chamber and the activity of a compound was evaluated as a percentage of control of the disease compared to no treatment when an appropriate level of disease lesions appears on untreated control leaf segments (7 to 9 days after application).

[0161] The following compounds at 200 ppm in the applied formulation resulted in at least 80% disease control in this test compared to untreated control leaf discs under the same conditions, which show extensive disease development. (Table A) A.1, A.2, A.4, A.5, A.6, A.8, A.9, A.10, A.11, A.14, A.15, A. 16, A.17, A.18, A.19, A.20, A.21, A.22, A.23, A.24, A.25, A.26, A.27, A.28, A.29, A.30, A.31, A.32, A.33, A.34, A.35, A.36, A.37, A.38, A.39, A.40, A. 41, A.42, A.43. (Table B) B.2, B.3, B.4, B.5, B.6, B.7, B.10, B.11, B.13, B.15, B.19, B. 21, B.22, B.23.

Example 2: Fungicidal activity against Puccinia recondita f. sp. tritici / wheat / dressing on leaf discs (Brown Rust)

[0162] Leaf segments of wheat cv. Kanzler are placed on agar in multi-well plates (24-well format). The leaf segments are then inoculated with a suspension of fungal spores. The plates were stored in the dark at 19 °C and 75% relative humidity. The formulated test compound diluted in water was applied 1 day after inoculation. Leaf segments were incubated at 19 °C and 75% relative humidity under a light regime of 12 hours light/12 hours dark in a climate-controlled chamber and the activity of a compound was evaluated as a percentage of disease control compared with no treatment when an appropriate level of disease lesions appears on untreated control leaf segments (6 to 8 days after application).

[0163] The following compounds at 200 ppm in the applied formulation resulted in disease control of at least 80% 164/165 in this test compared to untreated control leaf discs under the same conditions, which show extensive disease development. (Table A) A.1, A.3, A.4, A.5, A.6, A.8, A.9, A.10, A.11, A.13, A.14, A. 15, A.16, A.17, A.18, A.20, A.21, A.22, A.24, A.26, A.27, A.28, A.29, A.30, A.31, A.32, A.34, A.35, A.36, A.37, A.38, A.39, A.40, A.41, A.42, A.43. (Table B) B.22.

Example 3: Fungicidal activity against Phakopsora pachyrhizi/soybean/preventative on leaf discs (Asian soybean rust)

[0164] Soybean leaf discs are placed in water agar in multi-well plates (24-well format) and sprayed with the formulated test compound diluted in water. One day after application, leaf discs are inoculated by spraying a spore suspension onto the lower leaf surface. After an incubation period in a climate-controlled chamber of 24-36 hours in darkness at 20 °C and 75% RH, the leaf discs are maintained at 20 °C with 12 h light/day and 75% RH. The activity of a compound is evaluated as percentage of disease control compared to no treatment when an appropriate level of disease lesions appears on untreated control leaf discs (12 to 14 days after application).

[0165] The following compounds at 200 ppm in the applied formulation resulted in at least 80% disease control in this test compared to untreated control leaf discs under the same conditions, which show 165/165 extensive disease development. (Table A) A.1, A.6, A.8, A.9, A.14, A.17, A.20, A.22, A.24, A.26, A.28, A. 30, A.31, A.32, A.34, A.35, A.36, A.37, A.38, A.39, A.40, A.41, A.42, A.43.

Example 4: Fungicidal activity against Glomerella lagenarium (Colletotrichum lagenarium) liquid culture / cucumber / preventative (Anthracnose)

[0166] Cryogenic storage fungus conidia are directly mixed in nutrient broth (PDB - potato broth and dextrose). After placing a solution (DMSO) of the test compound in a microtiter plate (96-well format), nutrient broth containing the fungal spores is added. Test plates are incubated at 24°C and growth inhibition is measured photometrically 3 to 4 days after application.

[0167] The following compounds at 20 ppm in the applied formulation give disease control of at least 80% in this test compared to untreated control under the same conditions, which show extensive disease development. (Table A) A.1, A.2, A.3, A.4, A.5, A.6, A.7, A.8, A.9, A.10, A.11, A. 12, A.13, A.14, A.15, A.16, A.17, A.18, A.19, A.20, A.21, A.22, A.23, A.24, A.25, A.26, A.27, A.28, A.29, A.30, A.31, A.32, A.33, A.34, A.35, A.36, A. 37, A.38, A.39, A.40, A.41, A.42, A.43. (Table B) B.1, B.2, B.3, B.4, B.5, B.6, B.7, B.9, B.10, B.11, B.13, B. 15, B.16, B.19, B.20, B.21, B.22, B.23, B.24.

Claims (14)

1. Compound of formula (I): characterized by the fact that R1, R2, R3, R4 are independently selected from hydrogen or fluorine and wherein 0, 1 or 2 of R1, R2, R3 and R4 are fluorine; R5 and R6 are independently selected from hydrogen or C1-4alkyl; and Z represents Z1 or Z2: where R7 represents: (i) -C(O)N(Ra)(Rb), where: Ra is hydrogen, C1-5alkyl, C3-6cycloalkyl, C1- 4haloalkyl, C3-5alkenyl, C3-4alkynyl, C1- 4alkoxy, C1-2alkoxyC1-2alkyl, C3-5alkenyloxy, C3-6cycloalkylC1-4alkoxy, C1-4haloalkoxy, C3-4alkynyloxy, benzyl, furylmethyl, morpholin-4-yl, piperidin-1-yl, N,N-diC1-4alkylamino, phenyl, C3-6cycloalkylC1-4alkyl, C3-6halocycloalkylC1-4alkyl, N-formyl-N-(methyl)amino, isoxazolidin-2-yl, 5-azaspiro[2.4]heptan-5-yl; and Rb is hydrogen, C1-5alkyl, C3-6cycloalkyl, C3-5alkenyl, C3-4alkynyl; or Ra and Rb, together with the nitrogen atom to which they are attached, form a 4-, 5- or 6-membered cycle optionally containing an additional heteroatom or group selected from O, S, S(O)2, C(O) and NRc, where Rc is hydrogen, methyl, methoxy, formyl or acyl; or (ii) -C(O)ORd, where: Rd is hydrogen, C1-5alkyl, C1-4haloalkyl, tetrahydrofuranyl, oxetanyl, C3-6cycloalkyl, C3-5alkenyl, C1-4alkoxyC1-4alkyl, phenyl, benzyl, C3-6cycloalkylC1-4alkyl, C3-4alkynyl; or a salt or an N-oxide thereof. 2. Compound according to claim 1, characterized by the fact that R1 to R4 are hydrogen. 3. Compound according to any one of claims 1 and 2, characterized by the fact that R5 and R6 are hydrogen. 4. Compound according to any one of claims 1, 2 and 3, characterized by the fact that R7 is -C(O)N(Ra)(Rb). 5. Compound according to any one of claims 1, 2, 3 and 4, characterized in that Ra is hydrogen, C1-5alkyl, C1-4haloalkyl, C3-5alkenyl or C3-4alkynyl. 6. Compound according to any one of claims 1, 2, 3, 4 and 5, characterized in that Ra is hydrogen or C1-5alkyl. 7. Compound according to any one of claims 1, 2, 3, 4, 5 and 6, characterized in that Rb is hydrogen, C1-5alkyl or cyclopropyl. 8. Compound according to any one of claims 1, 2, 3, 4, 5, 6 and 7, characterized in that Rb is hydrogen or cyclopropyl. 9. Compound according to any one of claims 1, 2 and 3, characterized by the fact that R7 is -C(O)ORd. 10. Compound according to any one of claims 1, 2 and 3 or 9, characterized in that Rd is C1-5alkyl, C1-4fluoroalkyl, tetrahydrofuranyl, oxetanyl, C3-6cycloalkyl, C3-5alkenyl, C1- 2alkoxyC1-2alkyl, phenyl, benzyl, C3-6cycloalkylC1-2alkyl, C3-4alkynyl. 11. Agrochemical composition characterized by the fact that it comprises a fungicidal effective amount of a compound of Formula (I), as defined in any of claims 1, 2, 3, 4, 5, 6, 7, 8, 9 and 10. 12. Composition, according to claim 11, characterized by the fact that it additionally comprises at least one additional active ingredient and/or an agrochemically acceptable diluent or carrier. 13. Method of controlling or preventing infestation of useful plants by phytopathogenic microorganisms, characterized by the fact that a fungicidal effective amount of a compound of Formula (I), as defined in any one of claims 1, 2, 3, 4 , 5, 6, 7, 8, 9 and 10, or a composition comprising this compound as an active ingredient, is applied to plants, their parts or their locus. 14. Use of a compound of Formula (I), as defined in any one of claims 1, 2, 3, 4, 5, 6, 7, 8, 9 and 10, characterized by the fact that it is used as a fungicide.