US5242794A
(en)
|
1984-12-13 |
1993-09-07 |
Applied Biosystems, Inc. |
Detection of specific sequences in nucleic acids
|
US5019384A
(en)
|
1986-06-30 |
1991-05-28 |
Massachusetts Institute Of Technology |
Immunonodulating compositions and their use
|
US4988617A
(en)
|
1988-03-25 |
1991-01-29 |
California Institute Of Technology |
Method of detecting a nucleotide change in nucleic acids
|
WO1989012624A2
(en)
|
1988-06-14 |
1989-12-28 |
Cetus Corporation |
Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom
|
US5168038A
(en)
|
1988-06-17 |
1992-12-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
In situ transcription in cells and tissues
|
US5744101A
(en)
|
1989-06-07 |
1998-04-28 |
Affymax Technologies N.V. |
Photolabile nucleoside protecting groups
|
US5527681A
(en)
|
1989-06-07 |
1996-06-18 |
Affymax Technologies N.V. |
Immobilized molecular synthesis of systematically substituted compounds
|
US5242974A
(en)
|
1991-11-22 |
1993-09-07 |
Affymax Technologies N.V. |
Polymer reversal on solid surfaces
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
US5424186A
(en)
|
1989-06-07 |
1995-06-13 |
Affymax Technologies N.V. |
Very large scale immobilized polymer synthesis
|
DE3920358A1
(en)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
BISPECIFIC AND OLIGO-SPECIFIC, MONO- AND OLIGOVALENT ANTI-BODY CONSTRUCTS, THEIR PRODUCTION AND USE
|
US5252743A
(en)
|
1989-11-13 |
1993-10-12 |
Affymax Technologies N.V. |
Spatially-addressable immobilization of anti-ligands on surfaces
|
US5494810A
(en)
|
1990-05-03 |
1996-02-27 |
Cornell Research Foundation, Inc. |
Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
|
US5210015A
(en)
|
1990-08-06 |
1993-05-11 |
Hoffman-La Roche Inc. |
Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
|
WO1993012227A1
(en)
|
1991-12-17 |
1993-06-24 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5733523A
(en)
|
1990-12-10 |
1998-03-31 |
Akzo Nobel N.V. |
Targeted delivery of a therapeutic entity using complementary oligonucleotides
|
JP3266311B2
(en)
|
1991-05-02 |
2002-03-18 |
生化学工業株式会社 |
Novel polypeptide and anti-HIV agent using the same
|
US5384261A
(en)
|
1991-11-22 |
1995-01-24 |
Affymax Technologies N.V. |
Very large scale immobilized polymer synthesis using mechanically directed flow paths
|
US5550215A
(en)
|
1991-11-22 |
1996-08-27 |
Holmes; Christopher P. |
Polymer reversal on solid surfaces
|
ATE241426T1
(en)
|
1991-11-22 |
2003-06-15 |
Affymetrix Inc A Delaware Corp |
METHOD FOR PRODUCING POLYMER ARRAYS
|
US5324633A
(en)
|
1991-11-22 |
1994-06-28 |
Affymax Technologies N.V. |
Method and apparatus for measuring binding affinity
|
EP1136556B1
(en)
|
1991-11-25 |
2005-06-08 |
Enzon, Inc. |
Method of producing multivalent antigen-binding proteins
|
US5491074A
(en)
|
1993-04-01 |
1996-02-13 |
Affymax Technologies Nv |
Association peptides
|
US5858659A
(en)
|
1995-11-29 |
1999-01-12 |
Affymetrix, Inc. |
Polymorphism detection
|
US5837832A
(en)
|
1993-06-25 |
1998-11-17 |
Affymetrix, Inc. |
Arrays of nucleic acid probes on biological chips
|
US5925517A
(en)
|
1993-11-12 |
1999-07-20 |
The Public Health Research Institute Of The City Of New York, Inc. |
Detectably labeled dual conformation oligonucleotide probes, assays and kits
|
US5578832A
(en)
|
1994-09-02 |
1996-11-26 |
Affymetrix, Inc. |
Method and apparatus for imaging a sample on a device
|
US5631734A
(en)
|
1994-02-10 |
1997-05-20 |
Affymetrix, Inc. |
Method and apparatus for detection of fluorescently labeled materials
|
US6090555A
(en)
|
1997-12-11 |
2000-07-18 |
Affymetrix, Inc. |
Scanned image alignment systems and methods
|
AU2360195A
(en)
|
1994-05-05 |
1995-11-29 |
Beckman Instruments, Inc. |
Oligonucleotide repeat arrays
|
US5571639A
(en)
|
1994-05-24 |
1996-11-05 |
Affymax Technologies N.V. |
Computer-aided engineering system for design of sequence arrays and lithographic masks
|
US5795716A
(en)
|
1994-10-21 |
1998-08-18 |
Chee; Mark S. |
Computer-aided visualization and analysis system for sequence evaluation
|
US5599695A
(en)
|
1995-02-27 |
1997-02-04 |
Affymetrix, Inc. |
Printing molecular library arrays using deprotection agents solely in the vapor phase
|
US5750341A
(en)
|
1995-04-17 |
1998-05-12 |
Lynx Therapeutics, Inc. |
DNA sequencing by parallel oligonucleotide extensions
|
US5624711A
(en)
|
1995-04-27 |
1997-04-29 |
Affymax Technologies, N.V. |
Derivatization of solid supports and methods for oligomer synthesis
|
SE504798C2
(en)
|
1995-06-16 |
1997-04-28 |
Ulf Landegren |
Immunoassay and test kits with two reagents that can be cross-linked if adsorbed to the analyte
|
US5968740A
(en)
|
1995-07-24 |
1999-10-19 |
Affymetrix, Inc. |
Method of Identifying a Base in a Nucleic Acid
|
US6852487B1
(en)
|
1996-02-09 |
2005-02-08 |
Cornell Research Foundation, Inc. |
Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
|
US5981956A
(en)
|
1996-05-16 |
1999-11-09 |
Affymetrix, Inc. |
Systems and methods for detection of labeled materials
|
EP0912761A4
(en)
|
1996-05-29 |
2004-06-09 |
Cornell Res Foundation Inc |
Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
|
CA2257109C
(en)
|
1996-06-04 |
2009-10-06 |
University Of Utah Research Foundation |
Monitoring hybridization during pcr
|
GB9703369D0
(en)
|
1997-02-18 |
1997-04-09 |
Lindqvist Bjorn H |
Process
|
PT985032E
(en)
|
1997-05-28 |
2004-02-27 |
Discerna Ltd |
RIBOSOMIC COMPLEXES AS SELECTIVE PARTICLES FOR IN VITRO PRESENTATION AND EVOLUTION OF PROTEINS
|
JP2001521753A
(en)
|
1997-10-31 |
2001-11-13 |
アフィメトリックス インコーポレイテッド |
Expression profiles in adult and fetal organs
|
US6269846B1
(en)
|
1998-01-13 |
2001-08-07 |
Genetic Microsystems, Inc. |
Depositing fluid specimens on substrates, resulting ordered arrays, techniques for deposition of arrays
|
US6428752B1
(en)
|
1998-05-14 |
2002-08-06 |
Affymetrix, Inc. |
Cleaning deposit devices that form microarrays and the like
|
US6054276A
(en)
|
1998-02-23 |
2000-04-25 |
Macevicz; Stephen C. |
DNA restriction site mapping
|
US5936324A
(en)
|
1998-03-30 |
1999-08-10 |
Genetic Microsystems Inc. |
Moving magnet scanner
|
US6780591B2
(en)
|
1998-05-01 |
2004-08-24 |
Arizona Board Of Regents |
Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
|
WO1999057321A1
(en)
|
1998-05-01 |
1999-11-11 |
Arizona Board Of Regents |
Method of determining the nucleotide sequence of oligonucleotides and dna molecules
|
US6787308B2
(en)
|
1998-07-30 |
2004-09-07 |
Solexa Ltd. |
Arrayed biomolecules and their use in sequencing
|
EP1165839A2
(en)
|
1999-03-26 |
2002-01-02 |
Whitehead Institute For Biomedical Research |
Universal arrays
|
US6582938B1
(en)
|
2001-05-11 |
2003-06-24 |
Affymetrix, Inc. |
Amplification of nucleic acids
|
US7306904B2
(en)
|
2000-02-18 |
2007-12-11 |
Olink Ab |
Methods and kits for proximity probing
|
US6686184B1
(en)
|
2000-05-25 |
2004-02-03 |
President And Fellows Of Harvard College |
Patterning of surfaces utilizing microfluidic stamps including three-dimensionally arrayed channel networks
|
PL208712B1
(en)
|
2001-08-31 |
2011-05-31 |
Avidex Ltd |
Soluble t cell receptor
|
GB0127564D0
(en)
|
2001-11-16 |
2002-01-09 |
Medical Res Council |
Emulsion compositions
|
JP2006507921A
(en)
|
2002-06-28 |
2006-03-09 |
プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ |
Method and apparatus for fluid dispersion
|
JP4436319B2
(en)
|
2002-10-09 |
2010-03-24 |
メディジーン リミテッド |
Single-chain recombinant T cell receptor
|
US20060078893A1
(en)
|
2004-10-12 |
2006-04-13 |
Medical Research Council |
Compartmentalised combinatorial chemistry by microfluidic control
|
EP3616781A1
(en)
|
2003-04-10 |
2020-03-04 |
President and Fellows of Harvard College |
Formation and control of fluidic species
|
BRPI0414004A
(en)
|
2003-08-27 |
2006-10-24 |
Harvard College |
electronic control of fluidic species
|
US7169560B2
(en)
|
2003-11-12 |
2007-01-30 |
Helicos Biosciences Corporation |
Short cycle methods for sequencing polynucleotides
|
US20050221339A1
(en)
|
2004-03-31 |
2005-10-06 |
Medical Research Council Harvard University |
Compartmentalised screening by microfluidic control
|
US7643818B2
(en)
|
2004-11-22 |
2010-01-05 |
Seven Networks, Inc. |
E-mail messaging to/from a mobile terminal
|
EP2248578B1
(en)
|
2005-03-04 |
2012-06-06 |
President and Fellows of Harvard College |
Method for forming multiple emulsions
|
JP5452922B2
(en)
|
2005-09-13 |
2014-03-26 |
アフィメトリックス・インコーポレーテッド |
Coded microparticles
|
EP2363205A3
(en)
|
2006-01-11 |
2014-06-04 |
Raindance Technologies, Inc. |
Microfluidic Devices And Methods Of Use In The Formation And Control Of Nanoreactors
|
DE602007009811D1
(en)
|
2006-01-27 |
2010-11-25 |
Harvard College |
COALESCENCE FLUIDER DROPLET
|
GB0605584D0
(en)
|
2006-03-20 |
2006-04-26 |
Olink Ab |
Method for analyte detection using proximity probes
|
US20080014589A1
(en)
|
2006-05-11 |
2008-01-17 |
Link Darren R |
Microfluidic devices and methods of use thereof
|
WO2009014848A2
(en)
|
2007-06-25 |
2009-01-29 |
Affymetrix, Inc. |
Patterned microcodes
|
US8911948B2
(en)
|
2008-04-30 |
2014-12-16 |
Integrated Dna Technologies, Inc. |
RNase H-based assays utilizing modified RNA monomers
|
WO2009135093A2
(en)
|
2008-04-30 |
2009-11-05 |
Integrated Dna Technologies, Inc. |
Rnase-h-based assays utilizing modified rna monomers
|
GB2477053B
(en)
|
2008-09-23 |
2013-11-13 |
Quantalife Inc |
Droplet-based assay system
|
WO2011044186A1
(en)
|
2009-10-06 |
2011-04-14 |
The Board Of Trustees Of The University Of Illinois |
Human single-chain t cell receptors
|
CA2906076A1
(en)
*
|
2013-03-15 |
2014-09-18 |
Abvitro, Inc. |
Single cell bar-coding for antibody discovery
|
EP3736573A1
(en)
*
|
2013-03-15 |
2020-11-11 |
Prognosys Biosciences, Inc. |
Methods for detecting peptide/mhc/tcr binding
|
AU2015271324B2
(en)
*
|
2014-06-06 |
2019-09-12 |
Herlev Hospital |
Determining antigen recognition through barcoding of MHC multimers
|
JP6672310B2
(en)
*
|
2014-09-15 |
2020-03-25 |
アブビトロ, エルエルシー |
High-throughput nucleotide library sequencing
|
EP3757211A1
(en)
*
|
2014-12-19 |
2020-12-30 |
The Broad Institute, Inc. |
Methods for profiling the t-cell-receptor repertoire
|