BR0212098A - Método de isolamento de massa celular interna para o estabelecimento de linhas de células tronco embriÈnicas humanas (hesc) - Google Patents
Método de isolamento de massa celular interna para o estabelecimento de linhas de células tronco embriÈnicas humanas (hesc)Info
- Publication number
- BR0212098A BR0212098A BR0212098-4A BR0212098A BR0212098A BR 0212098 A BR0212098 A BR 0212098A BR 0212098 A BR0212098 A BR 0212098A BR 0212098 A BR0212098 A BR 0212098A
- Authority
- BR
- Brazil
- Prior art keywords
- embryonic stem
- human embryonic
- cell mass
- hesc
- establishment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/42—Gynaecological or obstetrical instruments or methods
- A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
- A61B17/435—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for embryo or ova transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Gynecology & Obstetrics (AREA)
- Surgery (AREA)
- Reproductive Health (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Otolaryngology (AREA)
- Pregnancy & Childbirth (AREA)
- Transplantation (AREA)
- Optics & Photonics (AREA)
- Electromagnetism (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
"MéTODO DE ISOLAMENTO DE MASSA CELULAR INTERNA PARA O ESTABELECIMENTO DE LINHAS DE CéLULAS TRONCO EMBRIÈNICAS HUMANAS (HESC)". Um método de isolamento de massa celular interna (ICM) que compreende as etapas de imobilização de um embrião em estágio de blastocisto tendo uma zona pelúcida, trofectoderma, e uma massa celular interna, criando um orifício no embrião em estágio de blastocisto por ablação a laser, e remoção da massa celular interna do embrião em estágio de blastocisto através do orifício. O orifício é através da zona pelúcida e trofectoderma. O orifício é atingido usando um laser de diodo de não contato. A massa celular interna removida do embrião em estágio de blastocisto é usada para estabelecer linhas de células tronco embriónicas humanas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31432301P | 2001-08-23 | 2001-08-23 | |
PCT/IN2002/000168 WO2003018783A1 (en) | 2001-08-23 | 2002-08-20 | ISOLATION OF INNER CELL MASS FOR THE ESTABLISHMENT OF HUMAN EMBRYONIC STEM CELL (hESC) LINES |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0212098A true BR0212098A (pt) | 2004-08-03 |
Family
ID=23219502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0212098-4A BR0212098A (pt) | 2001-08-23 | 2002-08-20 | Método de isolamento de massa celular interna para o estabelecimento de linhas de células tronco embriÈnicas humanas (hesc) |
Country Status (13)
Country | Link |
---|---|
US (2) | US7294508B2 (pt) |
EP (1) | EP1421181A1 (pt) |
JP (3) | JP2005514004A (pt) |
KR (1) | KR20040030161A (pt) |
CN (1) | CN1545549A (pt) |
AU (1) | AU2002334378B2 (pt) |
BR (1) | BR0212098A (pt) |
CA (1) | CA2458362A1 (pt) |
IL (2) | IL160351A0 (pt) |
RU (1) | RU2291703C2 (pt) |
SG (1) | SG172471A1 (pt) |
WO (1) | WO2003018783A1 (pt) |
ZA (1) | ZA200304132B (pt) |
Families Citing this family (43)
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US20050090004A1 (en) * | 2003-01-16 | 2005-04-28 | Sayre Chauncey B. | Stem cell maturation for all tissue lines |
US20030134422A1 (en) * | 2002-01-16 | 2003-07-17 | Sayre Chauncey Bigelow | Stem cell maturation for all tissue lines |
US20050170506A1 (en) * | 2002-01-16 | 2005-08-04 | Primegen Biotech Llc | Therapeutic reprogramming, hybrid stem cells and maturation |
EP1613726A4 (en) * | 2003-03-12 | 2007-08-22 | Reliance Life Sciences Pvt Ltd | DERIVATION OF DIFFERENTIATED DOPAMINERGER NEURONS OF HUMAN EMBRYONAL STEM CELLS |
US7820439B2 (en) * | 2003-09-03 | 2010-10-26 | Reliance Life Sciences Pvt Ltd. | In vitro generation of GABAergic neurons from pluripotent stem cells |
US20050272149A1 (en) | 2004-06-02 | 2005-12-08 | Life & Brain Gmbh | Therapeutic delivery of adenosine into a tissue |
DE102004062184B4 (de) | 2004-12-23 | 2013-08-01 | Wolfgang Würfel | Embryonenerhaltende Gewinnung pluripotenter embryonaler Stammzellen, derart gewonnene Stammzellen und Verwendung derselben |
WO2006091766A2 (en) | 2005-02-24 | 2006-08-31 | Jau-Nan Lee | Human trophoblast stem cells and use thereof |
US7811817B2 (en) | 2005-05-17 | 2010-10-12 | Reliance Life Sciences Pvt. Ltd. | Establishment of a human embryonic stem cell line using mammalian cells |
US20060269985A1 (en) * | 2005-05-31 | 2006-11-30 | Yasuhiko Kitayama | Method for constructing array blocks, and tissue punching instrument and tissue blocks used therefor |
CN101233226B (zh) * | 2005-06-22 | 2017-08-11 | 阿斯特利亚斯生物治疗股份公司 | 人胚胎干细胞的悬浮培养物 |
JP5497294B2 (ja) * | 2005-10-07 | 2014-05-21 | セルアーティス アーベー | 異種非含有hBS細胞株を得るための方法 |
WO2007079533A1 (en) * | 2006-01-10 | 2007-07-19 | South Eastern Sydney And Illawarra Area Health Service | Method for establishing and proliferating human esc by co-culturing with allogeneic feeder cells in serum-free media |
EP2245141B1 (en) | 2008-01-18 | 2018-03-14 | Regents of the University of Minnesota | Stem cell aggregates and methods for making and using |
WO2010114193A1 (ko) * | 2009-03-29 | 2010-10-07 | Kim Chang-Hyun | 내부 세포 덩어리의 분리 방법 및 이를 이용한 배아 줄기 세포주의 제조 방법 |
JP6243119B2 (ja) | 2009-07-21 | 2017-12-06 | エイビーティー ホールディング カンパニー | 白血球溢出を低下させる幹細胞の使用 |
ES2690199T3 (es) | 2009-07-21 | 2018-11-19 | Abt Holding Company | Uso de células madre para reducir la extravasación de leucocitos |
JP5115762B2 (ja) * | 2010-02-12 | 2013-01-09 | 有機合成薬品工業株式会社 | 4−ホルミルピペリジンアセタール誘導体の製造方法 |
JP2013520509A (ja) | 2010-02-25 | 2013-06-06 | エイビーティー ホールディング カンパニー | 血管形成の調節 |
SG183497A1 (en) | 2010-02-25 | 2012-09-27 | Abt Holding Co | Modulation of macrophage activation |
EP2568991B3 (en) | 2010-05-12 | 2018-11-28 | ABT Holding Company | Modulation of splenocytes in cell therapy |
US9090878B2 (en) | 2010-06-17 | 2015-07-28 | Katholieke Universiteit Leuven | Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells |
EP3875599A1 (en) | 2010-07-23 | 2021-09-08 | Astellas Institute for Regenerative Medicine | Methods for detection of rare subpopulations of cells and highly purified compositions of cells |
CN103237886B (zh) | 2010-08-24 | 2018-10-30 | 明尼苏达大学董事会 | 细胞集合体的非静态悬浮培养 |
WO2012048298A2 (en) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions |
GB2502704B (en) | 2010-11-15 | 2019-12-04 | Accelerated Biosciences Corp | Generation of neural stem cells from human trophoblast stem cells |
US8748178B2 (en) | 2010-11-23 | 2014-06-10 | The New York Stem Cell Foundation | Method for producing pluripotent stem cells |
EP2673358B1 (en) | 2011-02-08 | 2019-01-09 | FUJIFILM Cellular Dynamics, Inc. | Hematopoietic precursor cell production by programming |
SG10201604543PA (en) | 2011-06-06 | 2016-07-28 | ReGenesys BVBA | Expansion of stem cells in hollow fiber bioreactors |
GB201119335D0 (en) | 2011-11-09 | 2011-12-21 | Univ Leuven Kath | Hepatitis virus infectable stem cells |
CN102600507B (zh) * | 2012-03-08 | 2014-08-20 | 天津大学 | 一种细胞培养支架材料及其制备方法 |
CN113736873A (zh) | 2012-11-30 | 2021-12-03 | 艾克塞利瑞提德生物技术公司 | 通过调节mir-124分化干细胞的方法 |
AU2014250761B2 (en) | 2013-04-12 | 2019-02-28 | Robert J. Deans | Improving organs for transplantation |
AU2014266935B2 (en) | 2013-04-30 | 2020-06-11 | Katholieke Universiteit Leuven | Cell therapy for myelodysplastic syndromes |
CN105793411B (zh) | 2013-11-16 | 2018-04-17 | 泰尔茂比司特公司 | 生物反应器中的细胞扩增 |
US10202598B2 (en) | 2014-05-30 | 2019-02-12 | Todd Frank Ovokaitys | Methods and systems for generation, use, and delivery of activated stem cells |
CN107072716A (zh) | 2014-05-30 | 2017-08-18 | 托德.F.奥沃凯蒂斯 | 用于产生和使用活化的干细胞的方法和系统 |
WO2015187974A1 (en) | 2014-06-06 | 2015-12-10 | Ovokaitys Todd Frank | Methods and compositions for increasing the bioactivity of nutrients |
US10384985B2 (en) | 2014-06-06 | 2019-08-20 | B.K. Consultants, Inc. | Methods and compositions for increasing the yield of, and beneficial chemical composition of, certain plants |
CA2968065C (en) | 2014-11-26 | 2024-04-09 | Jau-Nan Lee | Induced hepatocytes and uses thereof |
CN104982419B (zh) * | 2015-07-29 | 2017-01-11 | 广西壮族自治区水牛研究所 | 一种结合激光破膜的水牛胚胎冷冻方法 |
US20200325449A1 (en) | 2016-06-02 | 2020-10-15 | The Cleveland Clinic Foundation | Complement inhibition for improving cell viability |
CN117716227A (zh) * | 2021-04-27 | 2024-03-15 | 多伦多纳米仪器有限公司 | 用于检测并对其他生物结构和胚泡的细胞结进行3d成像的系统和方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
WO2000027995A1 (en) * | 1998-11-09 | 2000-05-18 | Monash University | Embryonic stem cells |
IL151170A0 (en) | 2000-03-14 | 2003-04-10 | Es Cell Int Pte Ltd | Embryonic stem cells and neural progenitor cells derived therefrom |
-
2002
- 2002-08-20 RU RU2004108209/15A patent/RU2291703C2/ru not_active IP Right Cessation
- 2002-08-20 KR KR10-2004-7002520A patent/KR20040030161A/ko active Search and Examination
- 2002-08-20 JP JP2003523634A patent/JP2005514004A/ja active Pending
- 2002-08-20 EP EP02796348A patent/EP1421181A1/en not_active Withdrawn
- 2002-08-20 AU AU2002334378A patent/AU2002334378B2/en not_active Ceased
- 2002-08-20 CN CNA028164210A patent/CN1545549A/zh active Pending
- 2002-08-20 CA CA002458362A patent/CA2458362A1/en not_active Abandoned
- 2002-08-20 IL IL16035102A patent/IL160351A0/xx unknown
- 2002-08-20 SG SG2006043418A patent/SG172471A1/en unknown
- 2002-08-20 BR BR0212098-4A patent/BR0212098A/pt not_active Application Discontinuation
- 2002-08-20 WO PCT/IN2002/000168 patent/WO2003018783A1/en active Application Filing
- 2002-08-23 US US10/226,711 patent/US7294508B2/en not_active Expired - Fee Related
-
2003
- 2003-05-28 ZA ZA200304132A patent/ZA200304132B/en unknown
-
2004
- 2004-02-12 IL IL160351A patent/IL160351A/en not_active IP Right Cessation
-
2007
- 2007-11-13 US US11/939,397 patent/US20080064099A1/en not_active Abandoned
- 2007-11-30 JP JP2007311763A patent/JP2008099706A/ja active Pending
-
2008
- 2008-04-25 JP JP2008115762A patent/JP2008194055A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20030104616A1 (en) | 2003-06-05 |
JP2005514004A (ja) | 2005-05-19 |
IL160351A (en) | 2009-11-18 |
CN1545549A (zh) | 2004-11-10 |
IL160351A0 (en) | 2004-07-25 |
JP2008099706A (ja) | 2008-05-01 |
US7294508B2 (en) | 2007-11-13 |
US20080064099A1 (en) | 2008-03-13 |
WO2003018783A1 (en) | 2003-03-06 |
US20070048864A2 (en) | 2007-03-01 |
KR20040030161A (ko) | 2004-04-08 |
RU2004108209A (ru) | 2005-04-20 |
AU2002334378B2 (en) | 2008-02-28 |
CA2458362A1 (en) | 2003-03-06 |
EP1421181A1 (en) | 2004-05-26 |
SG172471A1 (en) | 2011-07-28 |
RU2291703C2 (ru) | 2007-01-20 |
ZA200304132B (en) | 2004-07-19 |
JP2008194055A (ja) | 2008-08-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
B15K | Others concerning applications: alteration of classification |
Ipc: A61B 17/435 (2006.01), A61B 18/20 (2006.01), C12N |
|
B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |