AU8427091A - Gamma-carboxylase and methods of use - Google Patents

Gamma-carboxylase and methods of use

Info

Publication number
AU8427091A
AU8427091A AU84270/91A AU8427091A AU8427091A AU 8427091 A AU8427091 A AU 8427091A AU 84270/91 A AU84270/91 A AU 84270/91A AU 8427091 A AU8427091 A AU 8427091A AU 8427091 A AU8427091 A AU 8427091A
Authority
AU
Australia
Prior art keywords
carboxylase
gamma
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU84270/91A
Inventor
Kathleen L. Berkner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of AU8427091A publication Critical patent/AU8427091A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/647Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02BINTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00Other engines
    • F02B75/02Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four
AU84270/91A 1990-07-23 1991-07-22 Gamma-carboxylase and methods of use Abandoned AU8427091A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US55722090A 1990-07-23 1990-07-23
US557220 1990-07-23
US66973591A 1991-03-14 1991-03-14
US669735 1991-03-14

Publications (1)

Publication Number Publication Date
AU8427091A true AU8427091A (en) 1992-02-18

Family

ID=27071365

Family Applications (1)

Application Number Title Priority Date Filing Date
AU84270/91A Abandoned AU8427091A (en) 1990-07-23 1991-07-22 Gamma-carboxylase and methods of use

Country Status (6)

Country Link
EP (1) EP0540650A1 (en)
JP (1) JPH05508551A (en)
AU (1) AU8427091A (en)
CA (1) CA2087970A1 (en)
IE (1) IE912600A1 (en)
WO (1) WO1992001795A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268275A (en) * 1991-05-08 1993-12-07 The University Of North Carolina At Chapel Hill Vitamin K-dependent carboxylase
US6903069B2 (en) 2000-10-02 2005-06-07 Novo Nordisk Health Care A/S Factor VII glycoforms
ES2339710T5 (en) * 2003-09-23 2017-10-05 University Of North Carolina At Chapel Hill Cells that coexpress vitamin K reductase and vitamin K dependent protein and use them to improve the productivity of said vitamin K dependent protein
GB0324044D0 (en) 2003-10-14 2003-11-19 Astrazeneca Ab Protein
EP1673450B1 (en) 2003-10-14 2010-04-28 Baxter International Inc. Vitamin k epoxide recycling polypeptide vkorc1, a therapeutic target of coumarin and their derivatives
WO2006089613A1 (en) 2005-02-28 2006-08-31 Baxter International Inc. Recombinant co-expression of vitamin k epoxide reductase subunit 1 to improve vitamin k dependent protein expression
US20090325226A1 (en) 2005-03-15 2009-12-31 Stafford Darrel W Methods and Compositions for Producing Active Vitamin K-Dependent Proteins
EP1874928A1 (en) 2005-04-13 2008-01-09 AstraZeneca AB A host cell comprising a vector for production of proteins requiring gamma-carboxylation
US20080045453A1 (en) * 2005-12-21 2008-02-21 Drohan William N Method of producing biologically active vitamin K dependent proteins by recombinant methods
US8206967B2 (en) 2007-07-06 2012-06-26 Medimmune Limited Method for production of recombinant human thrombin
US9631002B2 (en) 2010-12-21 2017-04-25 The University Of North Carolina At Chapel Hill Methods and compositions for producing active vitamin K-dependent proteins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8600206A (en) * 1986-01-29 1987-08-17 Univ Limburg METHOD FOR WINNING A VITAMIN K DEPENDENT CARBOXYLASE COMPLEX, METHOD FOR PREPARING ANTIBODIES WITH REGARD TO THE VITAMIN K DEPENDENT CARBOXYLASE / NON-CARBOXYLENE CONTAINING MATERIALS CARBON COMPLEX FACTOR COMPLEX CARBOXYLATION OF GLUTAMIC ACID CONTAINING EXOGENIC PRODUCTS WITH THESE CARRIER MATERIALS AND PHARMACEUTICAL PREPARATIONS BASED ON THE PRODUCTS PRODUCED BY THE latter.
WO1991001372A1 (en) * 1989-07-17 1991-02-07 New England Medical Center Hospitals, Inc. VITAMIN K-DEPENDENT η-CARBOXYLASE

Also Published As

Publication number Publication date
EP0540650A1 (en) 1993-05-12
WO1992001795A1 (en) 1992-02-06
CA2087970A1 (en) 1992-01-24
JPH05508551A (en) 1993-12-02
IE912600A1 (en) 1992-01-29

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