AU6826194A - 16-hydroxytriptolide composition and method for immunotherapy - Google Patents

16-hydroxytriptolide composition and method for immunotherapy

Info

Publication number
AU6826194A
AU6826194A AU68261/94A AU6826194A AU6826194A AU 6826194 A AU6826194 A AU 6826194A AU 68261/94 A AU68261/94 A AU 68261/94A AU 6826194 A AU6826194 A AU 6826194A AU 6826194 A AU6826194 A AU 6826194A
Authority
AU
Australia
Prior art keywords
hydroxytriptolide
immunotherapy
composition
hydroxytriptolide composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU68261/94A
Inventor
Renling Jin
Tien Wen Wiedmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmagenesis Inc
Original Assignee
Pharmagenesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmagenesis Inc filed Critical Pharmagenesis Inc
Publication of AU6826194A publication Critical patent/AU6826194A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
AU68261/94A 1993-05-06 1994-05-05 16-hydroxytriptolide composition and method for immunotherapy Abandoned AU6826194A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5832193A 1993-05-06 1993-05-06
US058321 1993-05-06
US22285394A 1994-04-05 1994-04-05
US222853 1994-04-05
PCT/US1994/004990 WO1994026265A1 (en) 1993-05-06 1994-05-05 16-hydroxytriptolide composition and method for immunotherapy

Publications (1)

Publication Number Publication Date
AU6826194A true AU6826194A (en) 1994-12-12

Family

ID=26737494

Family Applications (1)

Application Number Title Priority Date Filing Date
AU68261/94A Abandoned AU6826194A (en) 1993-05-06 1994-05-05 16-hydroxytriptolide composition and method for immunotherapy

Country Status (2)

Country Link
AU (1) AU6826194A (en)
WO (1) WO1994026265A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849730A (en) * 1994-08-31 1998-12-15 Pfizer Inc. Process for preparing demethylrapamycins
ID18663A (en) * 1996-04-12 1998-04-30 Novartis Ag COMPOSITION OF PHARMACEUTICAL PLATED PHARMACEUTICALS
US6004999A (en) * 1997-05-23 1999-12-21 Hoechst Marion Roussel, Inc. Triptolide derivatives useful in the treatment of autoimmune diseases
US5972998A (en) * 1997-05-23 1999-10-26 Hoechst Marion Roussel, Inc. Triptolide derivatives useful in the treatment of autoimmune diseases
DE69822297T2 (en) * 1997-05-23 2004-07-29 Aventis Pharmaceuticals Inc. TRIPTOLID DERIVATIVES SUITABLE FOR THE TREATMENT OF AUTOIMMUNE DISEASES
US6329148B1 (en) * 1999-02-16 2001-12-11 The Board Of Trustees Of The Leland Stanford University Combined therapy of diterpenoid triepoxides and death domain receptor ligands for synergistic killing of tumor cells
EP1330459B1 (en) 2000-10-02 2006-08-02 Emory University Triptolide analogs for the treatment of autoimmune and inflammatory disorders
CA2485794C (en) 2002-05-31 2012-10-16 Pharmagenesis, Inc. Triptolide derivatives for modulation of apoptosis and immunosuppression
WO2005062913A2 (en) 2003-12-24 2005-07-14 Pharmagenesis, Inc. Triplide 5,6-derivatives as immunomodulators and anticancer agents
WO2005077008A2 (en) 2004-02-09 2005-08-25 Pharmagenesis, Inc. Methods for isolation of triptolide compounds from tripterygium wilfordii
CA2557260C (en) 2004-03-02 2013-02-12 Pharmagenesis, Inc. Triptolide lactone ring derivatives as immunomodulators and anticancer agents
EP1768662A2 (en) 2004-06-24 2007-04-04 Novartis Vaccines and Diagnostics, Inc. Small molecule immunopotentiators and assays for their detection
WO2006044496A2 (en) 2004-10-13 2006-04-27 Pharmagenesis, Inc. Identification and screening of triptolide target molecules
WO2019014667A1 (en) * 2017-07-14 2019-01-17 The Regents Of The University Of California Novel methods of predicting transplant rejection risk

Also Published As

Publication number Publication date
WO1994026265A1 (en) 1994-11-24

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