AU6489996A - Methods for increasing protein expression - Google Patents

Methods for increasing protein expression

Info

Publication number
AU6489996A
AU6489996A AU64899/96A AU6489996A AU6489996A AU 6489996 A AU6489996 A AU 6489996A AU 64899/96 A AU64899/96 A AU 64899/96A AU 6489996 A AU6489996 A AU 6489996A AU 6489996 A AU6489996 A AU 6489996A
Authority
AU
Australia
Prior art keywords
methods
protein expression
increasing protein
increasing
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU64899/96A
Inventor
Christopher B. Glascock
Michael J. Weickert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Somatogen Inc
Original Assignee
Somatogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somatogen Inc filed Critical Somatogen Inc
Publication of AU6489996A publication Critical patent/AU6489996A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
AU64899/96A 1995-07-14 1996-07-12 Methods for increasing protein expression Abandoned AU6489996A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US001179 1993-01-06
US117995P 1995-07-14 1995-07-14
PCT/US1996/011600 WO1997004110A1 (en) 1995-07-14 1996-07-12 Methods for increasing protein expression

Publications (1)

Publication Number Publication Date
AU6489996A true AU6489996A (en) 1997-02-18

Family

ID=21694778

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64899/96A Abandoned AU6489996A (en) 1995-07-14 1996-07-12 Methods for increasing protein expression

Country Status (2)

Country Link
AU (1) AU6489996A (en)
WO (1) WO1997004110A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6022849A (en) * 1987-05-16 2000-02-08 Baxter Biotech Technology Saarl Mutant recombinant hemoglobins containing heme pocket mutations
US6204009B1 (en) 1988-05-16 2001-03-20 BAXTER BIOTECH TECHNOLOGY SàRL Nucleic acids encoding mutant recombinant hemoglobins containing heme pocket mutations
AU3904497A (en) 1996-08-02 1998-02-25 Somatogen, Inc. Methods of controlling beta dimer formation in hemoglobin
EP1950298A3 (en) 1997-05-02 2008-12-24 Baxter Biotech Technology S.A.R.L. Hemoglobin mutants with increased soluble expression and/or reduced nitric oxide scavenging
AU750295B2 (en) * 1997-05-02 2002-07-11 Baxter Biotech Technology S.A.R.L. Hemoglobin mutants with increased soluble expression and/or reduced nitric oxide scavenging
US7390645B2 (en) 1997-11-20 2008-06-24 William Marsh Rice University Lactose repressor proteins with increased operator DNA binding affinity
AU1467399A (en) * 1997-11-20 1999-06-15 William Marsh Rice University Lactose repressor proteins with altered ligand responsivity
US6180391B1 (en) * 1998-01-28 2001-01-30 Amgen Inc. Highly efficient controlled expression of exogenous genes in e. coli
US20030190740A1 (en) 1998-10-13 2003-10-09 The University Of Georgia Research Foundation, Inc Stabilized bioactive peptides and methods of identification, synthesis, and use
WO2000022112A1 (en) * 1998-10-13 2000-04-20 The University Of Georgia Research Foundation, Inc. Stabilized bioactive peptides and methods of identification, synthesis and use
CN1906294B (en) 2003-11-19 2013-09-11 陶氏环球技术公司 Improved protein expression systems
ES2299284B1 (en) * 2004-11-04 2009-04-16 Universidad Pablo De Olavide CONTROL OF GENE EXPRESSION THROUGH THE USE OF A TRANSCRIPTION ATTENATOR.
SG160329A1 (en) 2005-02-18 2010-04-29 Novartis Vaccines & Diagnostic Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli
CN101203529A (en) 2005-02-18 2008-06-18 诺华疫苗和诊断公司 Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli
EP2064230A2 (en) 2006-08-16 2009-06-03 Novartis AG Immunogens from uropathogenic escherichia coli
US8623652B2 (en) 2009-04-06 2014-01-07 Lucigen Corporation Host-vector system for cloning and expressing genes
AR124921A1 (en) 2021-02-18 2023-05-17 Novozymes As INACTIVE HEME-CONTAINING POLYPEPTIDES

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE60803T1 (en) * 1983-06-27 1991-02-15 Genentech Inc TRANSFERABLE INDUCIBLE CONTROL SYSTEMS CONTAINING EXPRESSION VECTORS, MICROORGANISMS TRANSFORMED WITH THEM AND THEIR USE IN EXOGENIC PROTEIN EXPRESSION.
DE3819463A1 (en) * 1988-06-08 1989-12-14 Behringwerke Ag EXPRESSION VECTORS FOR THE PRODUCTION OF UNFUSIONED PROTEINS IN MICROORGANISMS
ES2204926T3 (en) * 1989-05-10 2004-05-01 Baxter Biotech Technology S. .R.L. PROCEDURE FOR PREPARATION OF HEMOGLOBIN AND HEMOGLOBIN DERIVATIVES FROM HANDLING OF BACTERIA AND LEAVES.

Also Published As

Publication number Publication date
WO1997004110A1 (en) 1997-02-06

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