AU6246599A - Method of producing permuteins by scanning permutagenesis - Google Patents

Method of producing permuteins by scanning permutagenesis

Info

Publication number
AU6246599A
AU6246599A AU62465/99A AU6246599A AU6246599A AU 6246599 A AU6246599 A AU 6246599A AU 62465/99 A AU62465/99 A AU 62465/99A AU 6246599 A AU6246599 A AU 6246599A AU 6246599 A AU6246599 A AU 6246599A
Authority
AU
Australia
Prior art keywords
permutagenesis
permuteins
scanning
producing
scanning permutagenesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU62465/99A
Inventor
Stephen C Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of AU6246599A publication Critical patent/AU6246599A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU62465/99A 1998-09-25 1999-09-24 Method of producing permuteins by scanning permutagenesis Abandoned AU6246599A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10190898P 1998-09-25 1998-09-25
US60101908 1998-09-25
PCT/US1999/020891 WO2000018905A1 (en) 1998-09-25 1999-09-24 Method of producing permuteins by scanning permutagenesis

Publications (1)

Publication Number Publication Date
AU6246599A true AU6246599A (en) 2000-04-17

Family

ID=22287118

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62465/99A Abandoned AU6246599A (en) 1998-09-25 1999-09-24 Method of producing permuteins by scanning permutagenesis

Country Status (3)

Country Link
EP (1) EP1115854A1 (en)
AU (1) AU6246599A (en)
WO (1) WO2000018905A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5581476A (en) 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
CA2386090A1 (en) * 1999-10-27 2001-05-03 California Institute Of Technology Production of functional hybrid genes and proteins
US8288322B2 (en) 2000-04-17 2012-10-16 Dyax Corp. Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
AU2001253589B2 (en) * 2000-04-17 2007-08-16 Dyax Corp Methods of constructing display libraries of genetic packages for members of a diverse family of peptides
CA2784251A1 (en) 2000-12-18 2002-08-08 Dyax Corp. Focused libraries of genetic packages
IL159524A0 (en) 2001-07-11 2004-06-01 Maxygen Holdings Ltd G-csf conjugates
US20040067532A1 (en) 2002-08-12 2004-04-08 Genetastix Corporation High throughput generation and affinity maturation of humanized antibody
GB0315182D0 (en) * 2003-06-28 2003-08-06 Asterion Ltd Cytokine variant polypeptides
US7381805B2 (en) 2005-06-01 2008-06-03 Maxygen Holdings, Ltd. Compositions comprising mixtures of positional PEG isomers of PEGylated G-CSF
BRPI0816785A2 (en) 2007-09-14 2017-05-02 Adimab Inc rationally designed synthetic antibody libraries, and uses thereof
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
US9873957B2 (en) 2008-03-13 2018-01-23 Dyax Corp. Libraries of genetic packages comprising novel HC CDR3 designs
ES2528963T3 (en) 2008-04-24 2015-02-13 Dyax Corp. Genetic package libraries comprising new designs of CDR1, CDR2, and CDR3 of HC and new designs of CDR1, CDR2, and CDR3 of LC
EP2593594B1 (en) 2010-07-16 2017-09-27 Adimab, LLC Antibody libraries

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0859843A1 (en) * 1995-10-05 1998-08-26 G.D. Searle & Co. Novel g-csf receptor agonists

Also Published As

Publication number Publication date
WO2000018905A9 (en) 2000-10-26
EP1115854A1 (en) 2001-07-18
WO2000018905A1 (en) 2000-04-06

Similar Documents

Publication Publication Date Title
EP1144612A3 (en) Method of producing antihypercholesterolemic agents
AU2851699A (en) Method of producing ceramic foams
AU3091599A (en) Method of making dimethylnaphtalenes
AU2031500A (en) Method of producing nanocomposite coatings
AU6246599A (en) Method of producing permuteins by scanning permutagenesis
HUP0103905A3 (en) Method of producing wye-decalactone
AU1599600A (en) Method of producing hydrofluorocarbons
AU2002231683A1 (en) Method of producing alk-3-ene-1-ols
AU1877799A (en) Method for producing biocompatible surfaces
AU6084899A (en) Method for producing tetrahydrofuran
AU6341599A (en) Method of producing aspartic acid derivatives
AU9344298A (en) Method of producing substituted 2-nitroguanidine derivatives
AU5635799A (en) Method for producing decorative tiles
AU1658800A (en) Method for producing bisphenol-a
AU2912400A (en) Method for producing l-sorbose
AU2756699A (en) Method of producing dinitramide salts
AU5622099A (en) Method for producing transistors
AU2238799A (en) Improved method of making sulfanatophenyl substituted porphines
AU7798100A (en) Improved method for producing symmetrical anhydrides
AU4901599A (en) Method for producing phytosqualane
AU5389399A (en) Method of producing biofuel
AU3932599A (en) Method for producing shaped bodies
AU1283001A (en) Method for producing alkylhalogenosilanes
AU1502400A (en) Method for producing fluoxetin
AU1274701A (en) Method of producing polycarbonates

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase