AU5619298A - Beta-amyloid toxicity - Google Patents

Beta-amyloid toxicity

Info

Publication number
AU5619298A
AU5619298A AU56192/98A AU5619298A AU5619298A AU 5619298 A AU5619298 A AU 5619298A AU 56192/98 A AU56192/98 A AU 56192/98A AU 5619298 A AU5619298 A AU 5619298A AU 5619298 A AU5619298 A AU 5619298A
Authority
AU
Australia
Prior art keywords
beta
amyloid toxicity
amyloid
toxicity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU56192/98A
Inventor
Christopher Link
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Technology Corp
Original Assignee
University of Technology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Technology Corp filed Critical University of Technology Corp
Publication of AU5619298A publication Critical patent/AU5619298A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
    • A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
    • A01K67/0335—Genetically modified worms
    • A01K67/0336—Genetically modified Nematodes, e.g. Caenorhabditis elegans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/20—Animal model comprising regulated expression system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/70—Invertebrates
    • A01K2227/703—Worms, e.g. Caenorhabdities elegans
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0306—Animal model for genetic diseases
    • A01K2267/0312—Animal model for Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0337—Animal models for infectious diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0393—Animal model comprising a reporter system for screening tests
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
AU56192/98A 1997-01-03 1997-12-31 Beta-amyloid toxicity Abandoned AU5619298A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8022297P 1997-01-03 1997-01-03
US77864597A 1997-01-03 1997-01-03
US60080222 1997-01-03
US08778645 1997-01-03
PCT/US1997/023819 WO1998028971A2 (en) 1997-01-03 1997-12-31 Transgenic animals for in vivo visualization of beta-amyloid toxicity

Publications (1)

Publication Number Publication Date
AU5619298A true AU5619298A (en) 1998-07-31

Family

ID=26763238

Family Applications (1)

Application Number Title Priority Date Filing Date
AU56192/98A Abandoned AU5619298A (en) 1997-01-03 1997-12-31 Beta-amyloid toxicity

Country Status (3)

Country Link
EP (1) EP0948612A2 (en)
AU (1) AU5619298A (en)
WO (1) WO1998028971A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104920307A (en) * 2015-06-19 2015-09-23 安徽省农业科学院农业工程研究所 Caenorhabditis elegans fixing method suitable for single-particle microbeam device

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1294450B1 (en) * 1997-08-28 1999-03-25 Consiglio Nazionale Ricerche TRANSGENIC ANIMALS FOR THE STUDY OF PHYSICAL OR BIOLOGICAL CHEMICAL TOXIC AGENTS
AU6291899A (en) * 1998-10-09 2000-05-01 Regents Of The University Of California, The Viable prp (prion protein) transgenic animals and methods of use
DE19849073A1 (en) * 1998-10-24 2000-04-27 Aventis Pharma Gmbh Transgene encoding amyloid precursor protein or its fragment, used to produce transgenic nematodes used, e.g. to screen for agents for treating Alzheimer's disease
AU774183B2 (en) * 1998-12-17 2004-06-17 Xenogen Corporation Non-invasive evaluation of physiological response in a mammal
GB9906018D0 (en) * 1999-03-16 1999-05-12 Devgen Nv Expression of DNA or proteins in C.elegans
AU2589500A (en) * 1999-09-03 2001-04-10 Xenogen Corporation Targeting constructs and transgenic animals produced therewith
US6867348B1 (en) 1999-12-16 2005-03-15 Xenogen Corporation Methods and compositions for screening for angiogenesis modulating compounds
IT1311335B1 (en) 1999-12-21 2002-03-12 Otc Optical Technologies Ct S PROCEDURE AND DEVICE FOR MAKING FIBER OPTIC LICENSES.
JP3354918B2 (en) 2000-06-08 2002-12-09 佑子 若松 Transparent medaka
CN100422334C (en) * 2001-11-27 2008-10-01 内克西特股份有限公司 Production of eukaryotic proteins and nucleic acid molecules in c. elegans
FR2840320B1 (en) 2002-05-30 2007-07-20 Centre Nat Rech Scient XENOPE TRANSGENIC EMBRYOS AND USES THEREOF FOR THE DETECTION OF ENDOCRINE DISRUPTORS AND METHODS THEREOF
GB0517977D0 (en) * 2005-09-02 2005-10-12 Birkeland Innovasjon As Transgenic animal model for identifying modulators of protein kinase
DE102007035238A1 (en) * 2007-07-27 2009-01-29 Christian-Albrechts-Universität Zu Kiel Biological effect monitoring by transgenic Hydra
WO2011017319A1 (en) 2009-08-03 2011-02-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods of treating disorders associated with protein polymerization
US9072772B2 (en) 2009-11-05 2015-07-07 University of Pittsburgh—of the Commonwealth System of Higher Education Methods of treating disorders associated with protein aggregation
US8809617B2 (en) * 2009-11-05 2014-08-19 The University of Pittsburgh—Of the Commonwealth System of Higher Education Automated high-content live animal drug screening using C. elegans

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4240293A (en) * 1992-05-08 1993-12-13 Exemplar Corporation Anti-neoplastic in vivo drug screen
CA2088379A1 (en) * 1993-01-29 1994-07-30 University Of British Columbia Biological systems incorporating stress-inducible genes and reporter constructs for environmental biomonitoring and toxicology
ATE198622T1 (en) * 1993-10-27 2001-01-15 Elan Pharm Inc TRANSGENIC ANIMALS HOSTING APP ALLELES WITH THE SWEDISH MUTATION

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104920307A (en) * 2015-06-19 2015-09-23 安徽省农业科学院农业工程研究所 Caenorhabditis elegans fixing method suitable for single-particle microbeam device

Also Published As

Publication number Publication date
EP0948612A2 (en) 1999-10-13
WO1998028971A2 (en) 1998-07-09
WO1998028971A3 (en) 1998-10-29

Similar Documents

Publication Publication Date Title
AU1151099A (en) Azaoxindole derivatives
AU1825899A (en) Dota-biotin derivatives
AU1709299A (en) Mixer-injectors
AU8921698A (en) Follistatin-3
AU7935398A (en) Diaminorhodamine derivatives
AU6117998A (en) 3-oxadiazolylquinoxaline derivatives
AU6598798A (en) Resorcinyl-triazines
AU1027499A (en) 32P-polyphosphazene
AU5619298A (en) Beta-amyloid toxicity
AU6827898A (en) Detergent-package combination
AU5272198A (en) EMP-charge-eliminator
AU7813598A (en) Betulinol derivatives
AU6998698A (en) Dioxacycloalkan-8-one
AU4117497A (en) Micropolarimeter
AU1174199A (en) Biphenylamidine derivatives
AU6729498A (en) Thiazolimine derivatives
AUPO863197A0 (en) Novel derivatives
AU6185898A (en) Clavaspirins
AU7761998A (en) Korrosionsschutzanstrichstoff
AU8214598A (en) 3-benzylpiperidine
AU1562199A (en) Amino-benzothiazole derivatives
AU6115798A (en) Saponarin derivatives
AU1691399A (en) 5-arylpyrrole derivatives
AU9538898A (en) Pyrrolopyrrolone derivatives
AU8991998A (en) Renovative pipeliner