AU5184293A - Phthalazinone derivatives - Google Patents

Phthalazinone derivatives

Info

Publication number
AU5184293A
AU5184293A AU51842/93A AU5184293A AU5184293A AU 5184293 A AU5184293 A AU 5184293A AU 51842/93 A AU51842/93 A AU 51842/93A AU 5184293 A AU5184293 A AU 5184293A AU 5184293 A AU5184293 A AU 5184293A
Authority
AU
Australia
Prior art keywords
phthalazinone derivatives
phthalazinone
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU51842/93A
Inventor
Not Given Name
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU5184293A publication Critical patent/AU5184293A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • C07D237/32Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/22Nitrogen and oxygen atoms
AU51842/93A 1992-11-27 1993-11-22 Phthalazinone derivatives Abandoned AU5184293A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH365092 1992-11-27
CH3650/92 1992-11-27

Publications (1)

Publication Number Publication Date
AU5184293A true AU5184293A (en) 1994-06-09

Family

ID=4260564

Family Applications (1)

Application Number Title Priority Date Filing Date
AU51842/93A Abandoned AU5184293A (en) 1992-11-27 1993-11-22 Phthalazinone derivatives

Country Status (8)

Country Link
EP (1) EP0600831A1 (en)
JP (1) JPH06228108A (en)
KR (1) KR940011448A (en)
CN (1) CN1095714A (en)
AU (1) AU5184293A (en)
CA (1) CA2109992A1 (en)
IL (1) IL107749A0 (en)
ZA (1) ZA938847B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258812B1 (en) 1997-02-13 2001-07-10 Novartis Ag Phthalazines with angiogenesis inhibiting activity

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0111078D0 (en) 2001-05-04 2001-06-27 Novartis Ag Organic compounds
US20030073692A1 (en) 2001-08-07 2003-04-17 Pharmacia & Upjohn S.P.A. Amino-phthalazinone derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
GB0305681D0 (en) 2003-03-12 2003-04-16 Kudos Pharm Ltd Phthalazinone derivatives
GB0317466D0 (en) 2003-07-25 2003-08-27 Univ Sheffield Use
WO2005051301A2 (en) * 2003-11-19 2005-06-09 Array Biopharma Inc. Heterocyclic inhibitors of mek and methods of use thereof
CN102107008B (en) 2003-12-01 2013-04-03 库多斯药物有限公司 DNA damage repair inhibitors for treatment of cancer
US7759337B2 (en) * 2005-03-03 2010-07-20 Amgen Inc. Phthalazine compounds and methods of use
KR20090043559A (en) 2006-08-15 2009-05-06 에이전시 포 사이언스, 테크놀로지 앤드 리서치 Mesenchymal stem cell conditioned medium
KR101640381B1 (en) 2008-02-22 2016-07-18 에이전시 포 사이언스, 테크놀로지 앤드 리서치 Mesenchymal stem cell particles
SG188918A1 (en) 2008-03-17 2013-04-30 Agency Science Tech & Res
JP5892939B2 (en) 2009-11-02 2016-03-23 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ Method for monitoring cell status and method for immortalizing mesenchymal stem cells
SG183579A1 (en) 2011-02-11 2012-09-27 Agency Science Tech & Res Methods of detecting therapeutic exosomes
WO2015140005A1 (en) 2014-03-19 2015-09-24 Ifom Fondazione Istituto Firc Di Oncologia Molecolare Method of generation of pluripotent cells
CN110087658A (en) 2016-10-12 2019-08-02 新加坡科技研究局 A method of for excretion body to be lyophilized

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU653024B2 (en) * 1991-05-30 1994-09-15 Novartis Ag Substituted diaminophthalimides and analogues

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258812B1 (en) 1997-02-13 2001-07-10 Novartis Ag Phthalazines with angiogenesis inhibiting activity
US6514974B2 (en) 1997-02-13 2003-02-04 Novartis Ag Pyrido-, pyrimido-, pyridazo- and pyrazo- pyridazines having angiogenesis inhibiting activity

Also Published As

Publication number Publication date
CN1095714A (en) 1994-11-30
IL107749A0 (en) 1994-02-27
JPH06228108A (en) 1994-08-16
ZA938847B (en) 1994-05-27
KR940011448A (en) 1994-06-21
EP0600831A1 (en) 1994-06-08
CA2109992A1 (en) 1994-05-28

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