AU4988697A - Monophosphate prodrugs of beta-l-fd4c and beta-l-fddc as potent antiviral agents - Google Patents
Monophosphate prodrugs of beta-l-fd4c and beta-l-fddc as potent antiviral agentsInfo
- Publication number
- AU4988697A AU4988697A AU49886/97A AU4988697A AU4988697A AU 4988697 A AU4988697 A AU 4988697A AU 49886/97 A AU49886/97 A AU 49886/97A AU 4988697 A AU4988697 A AU 4988697A AU 4988697 A AU4988697 A AU 4988697A
- Authority
- AU
- Australia
- Prior art keywords
- beta
- fd4c
- fddc
- antiviral agents
- potent antiviral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73615696A | 1996-10-24 | 1996-10-24 | |
US08736156 | 1996-10-24 | ||
PCT/US1997/018860 WO1998017281A1 (en) | 1996-10-24 | 1997-10-23 | MONOPHOSPHATE PRODRUGS OF β-L-FD4C AND β-L-FddC AS POTENT ANTIVIRAL AGENTS |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4988697A true AU4988697A (en) | 1998-05-15 |
Family
ID=24958728
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU49886/97A Abandoned AU4988697A (en) | 1996-10-24 | 1997-10-23 | Monophosphate prodrugs of beta-l-fd4c and beta-l-fddc as potent antiviral agents |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU4988697A (en) |
WO (1) | WO1998017281A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1210354A1 (en) * | 1999-09-08 | 2002-06-05 | Metabasis Therapeutics, Inc. | Prodrugs for liver specific drug delivery |
JP2003530847A (en) | 2000-04-12 | 2003-10-21 | ヒューマン ゲノム サイエンシズ インコーポレイテッド | Albumin fusion protein |
CA2413160A1 (en) | 2000-06-15 | 2001-12-20 | Human Genome Sciences, Inc. | Human tumor necrosis factor delta and epsilon |
JP2005519916A (en) * | 2001-12-14 | 2005-07-07 | フアーマセツト・リミテツド | N4-acylcytosine nucleosides for the treatment of viral infection |
EP1463751B1 (en) | 2001-12-21 | 2013-05-22 | Human Genome Sciences, Inc. | Albumin fusion proteins |
US20040157793A1 (en) * | 2002-11-12 | 2004-08-12 | Stuyver Lieven J. | Modified nucleosides as antiviral agents |
US7892563B2 (en) | 2003-05-20 | 2011-02-22 | Wyeth Holdings Corporation | Methods for treatment of severe acute respiratory syndrome (SARS) |
EP1933873A4 (en) | 2005-10-13 | 2009-12-02 | Human Genome Sciences Inc | Methods and compositions for use in treatment of patients with autoantibody positive diseases |
US8076303B2 (en) | 2005-12-13 | 2011-12-13 | Spring Bank Pharmaceuticals, Inc. | Nucleotide and oligonucleotide prodrugs |
US8076476B2 (en) | 2007-11-15 | 2011-12-13 | Avi Biopharma, Inc. | Synthesis of morpholino oligomers using doubly protected guanine morpholino subunits |
US8299206B2 (en) | 2007-11-15 | 2012-10-30 | Avi Biopharma, Inc. | Method of synthesis of morpholino oligomers |
WO2011056650A2 (en) | 2009-10-27 | 2011-05-12 | Michael Zasloff | Methods and compositions for treating and preventing viral infections |
WO2011066260A2 (en) | 2009-11-25 | 2011-06-03 | Michael Zasloff | Formulations comprising aminosterols |
CN108239128B (en) | 2016-12-23 | 2019-03-29 | 江苏奥赛康药业股份有限公司 | The preparation method of beta-nucleosides class compound |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW374087B (en) * | 1993-05-25 | 1999-11-11 | Univ Yale | L-2',3'-dideoxy nucleotide analogs as anti-hepatitis B(HBV) and anti-HIV agents |
-
1997
- 1997-10-23 WO PCT/US1997/018860 patent/WO1998017281A1/en active Application Filing
- 1997-10-23 AU AU49886/97A patent/AU4988697A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1998017281A1 (en) | 1998-04-30 |
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