AU4954899A - Methods and compositions for modulating antigen-specific immunological (humoral)responses by targeting such antigen to apcs in conjunction with anti-cd40 ligan d administration - Google Patents
Methods and compositions for modulating antigen-specific immunological (humoral)responses by targeting such antigen to apcs in conjunction with anti-cd40 ligan d administrationInfo
- Publication number
- AU4954899A AU4954899A AU49548/99A AU4954899A AU4954899A AU 4954899 A AU4954899 A AU 4954899A AU 49548/99 A AU49548/99 A AU 49548/99A AU 4954899 A AU4954899 A AU 4954899A AU 4954899 A AU4954899 A AU 4954899A
- Authority
- AU
- Australia
- Prior art keywords
- antigen
- ligan
- apcs
- humoral
- targeting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9084998P | 1998-06-26 | 1998-06-26 | |
US60090849 | 1998-06-26 | ||
PCT/US1999/012825 WO2000000156A2 (en) | 1998-06-26 | 1999-06-25 | Methods for modulating immunological responses by targeting antigen to apcs in conjuction with anti-cd40 ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4954899A true AU4954899A (en) | 2000-01-17 |
Family
ID=22224621
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU49548/99A Abandoned AU4954899A (en) | 1998-06-26 | 1999-06-25 | Methods and compositions for modulating antigen-specific immunological (humoral)responses by targeting such antigen to apcs in conjunction with anti-cd40 ligan d administration |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU4954899A (en) |
WO (1) | WO2000000156A2 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7063845B2 (en) | 2000-04-28 | 2006-06-20 | Gemini Science, Inc. | Human anti-CD40 antibodies |
WO2001083755A2 (en) * | 2000-04-28 | 2001-11-08 | La Jolla Institute For Allergy And Immunology | Human anti-cd40 antibodies and methods of making and using same |
JP5007409B2 (en) | 2000-05-08 | 2012-08-22 | セルデックス リサーチ コーポレーション | Human monoclonal antibodies against dendritic cells |
US7560534B2 (en) * | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
CA2658221C (en) | 2001-04-27 | 2012-11-27 | Kyowa Hakko Kirin Co., Ltd. | Anti-cd40 monoclonal antibody |
US9809654B2 (en) | 2002-09-27 | 2017-11-07 | Vaccinex, Inc. | Targeted CD1d molecules |
US20040146948A1 (en) * | 2002-10-18 | 2004-07-29 | Centenary Institute Of Cancer Medicine And Cell Biology | Compositions and methods for targeting antigen-presenting cells with antibody single-chain variable region fragments |
US9259459B2 (en) | 2003-01-31 | 2016-02-16 | Celldex Therapeutics Inc. | Antibody vaccine conjugates and uses therefor |
ATE552860T1 (en) | 2003-01-31 | 2012-04-15 | Celldex Res Corp | ANTIBODY VACCINE CONJUGATES AND USES THEREOF |
JP5357782B2 (en) | 2007-02-21 | 2013-12-04 | バクシネックス インコーポレーティッド | Regulation of NKT cell activity by antigen-loaded CD1d molecules |
EP2570137A3 (en) | 2007-11-07 | 2013-08-21 | Celldex Therapeutics, Inc. | Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) |
AU2010222928B2 (en) * | 2008-07-16 | 2012-11-29 | Baylor Research Institute | Antigen presenting cell targeted vaccines |
EP2966091B1 (en) | 2008-07-16 | 2018-04-25 | Baylor Research Institute | Agonistic anti-cd40 antibodies |
WO2010104747A2 (en) | 2009-03-10 | 2010-09-16 | Baylor Research Institute | Antigen presenting cell targeted vaccines |
WO2010081026A1 (en) | 2009-01-08 | 2010-07-15 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Bacterial vaccines with cell wall-associated ceramide-like glycolipids and uses thereof |
FR2955773B1 (en) | 2010-02-01 | 2017-05-26 | Commissariat A L'energie Atomique | MOLECULAR COMPLEX FOR TARGETING ANTIGENS TO ANTIGEN-PRESENTING CELLS AND ITS APPLICATIONS FOR VACCINATION |
US9371352B2 (en) | 2013-02-08 | 2016-06-21 | Vaccinex, Inc. | Modified glycolipids and methods of making and using the same |
JP7037884B2 (en) | 2014-01-13 | 2022-03-17 | ベイラー リサーチ インスティテュート | New vaccines for HPV and HPV-related diseases |
US10610585B2 (en) | 2017-09-26 | 2020-04-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and compositions for treating and preventing HIV |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5247069A (en) * | 1986-06-13 | 1993-09-21 | Oncogen | Ligands and methods for augmenting B-cell proliferation |
DK8189A (en) * | 1988-01-12 | 1989-07-13 | Bunge Australia | ANTIGEN-ANTIBODY CONJUGATES, THEIR PREPARATION AND USE |
US5637481A (en) * | 1993-02-01 | 1997-06-10 | Bristol-Myers Squibb Company | Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell |
MX9204374A (en) * | 1991-07-25 | 1993-03-01 | Idec Pharma Corp | RECOMBINANT ANTIBODY AND METHOD FOR ITS PRODUCTION. |
-
1999
- 1999-06-25 WO PCT/US1999/012825 patent/WO2000000156A2/en active Application Filing
- 1999-06-25 AU AU49548/99A patent/AU4954899A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2000000156A3 (en) | 2007-08-16 |
WO2000000156A2 (en) | 2000-01-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU4954899A (en) | Methods and compositions for modulating antigen-specific immunological (humoral)responses by targeting such antigen to apcs in conjunction with anti-cd40 ligan d administration | |
AU2230199A (en) | Vaccine compositions and methods of modulating immune responses | |
AU2903999A (en) | Methods and compositions of chemokine-tumor antigen fusion proteins as cancer vaccines | |
AU2605501A (en) | Inducing cellular immune responses to prostate cancer antigens using peptide andnucleic acid compositions | |
EP0921816A4 (en) | Opsonin-enhanced cells, and methods of modulating an immune response to an antigen | |
AU7980794A (en) | Methods and compositions for microencapsulation of antigens for use as vaccines | |
AU2001255196A1 (en) | Compositions and methods for enhancing immunogenicity of antigens | |
AU709406C (en) | Combined vaccines comprising hepatitis B surface antigen and other antigens | |
AU6095696A (en) | Immunogenic peptides of prostate specific antigen | |
AU3188297A (en) | Liposomal influenza vaccine composition and method | |
AU4518196A (en) | Adjuvant-incorporated cellular antigens: conjugation and methods | |
HUP9901546A3 (en) | Helicobacter pylori antigens and vaccine compositions | |
AU3307497A (en) | Immunotherapy by modulation of antigen presentation | |
AU3896699A (en) | Use of neglected target tissue antigens in modulation of immune responses | |
WO2003012111A3 (en) | Conjugates for the modulation of immune responses | |
AU2086501A (en) | Inducing cellular immune responses to carcinoembryonic antigen using peptide andnucleic acid compositions | |
AU4642600A (en) | Methods and compositions for use in potentiating antigen presentation by antigenpresenting cells | |
AU1908395A (en) | Antibodies to mammalian natural killer antigens and uses | |
AU1865297A (en) | Methods and nucleic immunogenic compositions encoding antigens and co-stimulatory molecules for immunization | |
AU5784298A (en) | Lanthanum gallium silicate disc and its preparation method | |
AU2001292564A1 (en) | A method of transplantation using chemotherapy-treated allogeneic cells that enhance immune responses without graft versus host disease | |
AU7134598A (en) | Plant propagation compositions and methods | |
AU2289799A (en) | Vaccine composition comprising milled lyophilisate of antigenic whole cells | |
AU7410798A (en) | Heterologous antigens in live cell V | |
AU4343300A (en) | Methods and compositions for transforming cells using site-specific recombination |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |