AU4640985A - Benzimidazole derivatives - Google Patents
Benzimidazole derivativesInfo
- Publication number
- AU4640985A AU4640985A AU46409/85A AU4640985A AU4640985A AU 4640985 A AU4640985 A AU 4640985A AU 46409/85 A AU46409/85 A AU 46409/85A AU 4640985 A AU4640985 A AU 4640985A AU 4640985 A AU4640985 A AU 4640985A
- Authority
- AU
- Australia
- Prior art keywords
- benzimidazole derivatives
- benzimidazole
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59-182400 | 1984-08-31 | ||
JP59182400A JPS6160660A (en) | 1984-08-31 | 1984-08-31 | Benzimidazole derivative, its preparation, and antitumor agent containing it |
JP60-61194 | 1985-03-26 | ||
JP60061195A JPH0764826B2 (en) | 1985-03-26 | 1985-03-26 | Benzimidazole derivative |
JP60061194A JPH068283B2 (en) | 1985-03-26 | 1985-03-26 | Benzimidazole derivative, method for producing the same, and antiulcer agent containing the same |
JP60-61195 | 1985-03-26 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU41271/89A Division AU4127189A (en) | 1984-08-31 | 1989-09-11 | Benzimidazole derivatives, process for preparing the same and antiulcer agents containing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4640985A true AU4640985A (en) | 1986-03-06 |
Family
ID=27297422
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU46409/85A Abandoned AU4640985A (en) | 1984-08-31 | 1985-08-19 | Benzimidazole derivatives |
AU41271/89A Abandoned AU4127189A (en) | 1984-08-31 | 1989-09-11 | Benzimidazole derivatives, process for preparing the same and antiulcer agents containing the same |
AU29750/92A Ceased AU647978B2 (en) | 1984-08-31 | 1992-11-27 | Benzimidazole derivatives |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU41271/89A Abandoned AU4127189A (en) | 1984-08-31 | 1989-09-11 | Benzimidazole derivatives, process for preparing the same and antiulcer agents containing the same |
AU29750/92A Ceased AU647978B2 (en) | 1984-08-31 | 1992-11-27 | Benzimidazole derivatives |
Country Status (14)
Country | Link |
---|---|
KR (1) | KR920004936B1 (en) |
AR (1) | AR242195A1 (en) |
AU (3) | AU4640985A (en) |
BE (1) | BE903128A (en) |
BR (1) | BR8504252A (en) |
CH (1) | CH665417A5 (en) |
DE (1) | DE3531487C2 (en) |
ES (1) | ES8703142A1 (en) |
FR (1) | FR2569691B1 (en) |
GB (1) | GB2163747B (en) |
IT (1) | IT1189601B (en) |
MX (1) | MX159807A (en) |
NL (1) | NL8502384A (en) |
SE (1) | SE500669C2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU594074B2 (en) * | 1985-08-14 | 1990-03-01 | Nippon Chemiphar Co. Ltd. | Cytoprotective agent for gastrointestinal tract |
AU619444B2 (en) * | 1986-06-02 | 1992-01-30 | Nippon Chemiphar Co. Ltd. | 2-(2-aminobenzylsulfinyl)- benzimidazole derivatives |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8417194D0 (en) * | 1984-07-05 | 1984-08-08 | Boots Co Plc | Therapeutic agents |
GB2161160B (en) * | 1984-07-06 | 1989-05-24 | Fisons Plc | Heterocyclic sulphinyl compounds |
EP0174717B1 (en) | 1984-07-06 | 1992-01-22 | FISONS plc | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors |
US5869513A (en) * | 1985-05-24 | 1999-02-09 | G. D. Searle & Co. | 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines |
AU5768886A (en) * | 1985-05-24 | 1986-11-27 | G.D. Searle & Co. | 2-((1-h-benzimidazol-2-ylsulfinyl)methyl)benzenamines |
WO1987001114A2 (en) * | 1985-08-21 | 1987-02-26 | Byk Gulden Lomberg Chemische Fabrik Gmbh | New amines, process for their manufacture, their use and medicines containing them |
AR243167A1 (en) | 1985-08-24 | 1993-07-30 | Hoechst Ag | Substituted toluidines, process for their preparation, pharmaceutical compositions containing them and their use as gastric secretion inhibitors |
EP0251536A1 (en) * | 1986-06-24 | 1988-01-07 | FISONS plc | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors |
US4772619A (en) * | 1986-07-17 | 1988-09-20 | G. D. Searle & Co. | [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines |
US4687775A (en) * | 1986-07-17 | 1987-08-18 | G. D. Searle & Co. | 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles |
US4721718A (en) * | 1986-08-18 | 1988-01-26 | G. D. Searle & Co. | 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers |
DE3639926A1 (en) * | 1986-11-22 | 1988-06-01 | Hoechst Ag | SUBSTITUTED THIENOIMIDAZOLTOLUIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING IT AND THEIR USE AS AN INGESTIC ACID INHIBITOR |
IT1222412B (en) * | 1987-07-31 | 1990-09-05 | Chiesi Farma Spa | THYOMETHYL AND SULFINYL METHYL DERIVED WITH ANTI-SECRET ACID GASTRIC ACTION, THEIR PREPARATION PROCEDURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
JP2614756B2 (en) * | 1988-08-10 | 1997-05-28 | 日本ケミファ株式会社 | Imidazole derivative, method for producing the same, and anti-ulcer agent containing the same |
JPH06298611A (en) * | 1993-04-16 | 1994-10-25 | Nippon Chemiphar Co Ltd | Antibacterial agent |
SE9301489D0 (en) | 1993-04-30 | 1993-04-30 | Ab Astra | VETERINARY COMPOSITION |
SE9402431D0 (en) * | 1994-07-08 | 1994-07-08 | Astra Ab | New tablet formulation |
SE9500422D0 (en) * | 1995-02-06 | 1995-02-06 | Astra Ab | New oral pharmaceutical dosage forms |
SE9500478D0 (en) * | 1995-02-09 | 1995-02-09 | Astra Ab | New pharmaceutical formulation and process |
US5708017A (en) * | 1995-04-04 | 1998-01-13 | Merck & Co., Inc. | Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors |
HRP960232A2 (en) * | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
ES2236628T3 (en) * | 1995-09-21 | 2005-07-16 | Pharma Pass Ii Llc | PHARMACEUTICAL COMPOSITION CONTAINING A LABIL ACID OMEPRAZOL, AND PROCEDURE FOR PREPARATION. |
SE9600070D0 (en) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
US6380222B2 (en) | 1996-10-11 | 2002-04-30 | Astrazeneca Ab | Use of an H+, K+-atpase inhibitor in the treatment of nasal polyps |
EP1003554B1 (en) | 1997-07-25 | 2004-11-03 | ALTANA Pharma AG | Proton pump inhibitor in therapeutic combination with antibacterial substances |
SE9704869D0 (en) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulaton II |
SE9704870D0 (en) | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulation I |
JP4988088B2 (en) | 1998-08-12 | 2012-08-01 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | Oral dosage form composition of pyridin-2-ylmethylsulfinyl-1H-benzimidazole, a compound having a skeleton of pyridin-2-ylmethylsulfinyl-1H-benzimidazole, or a pharmaceutically acceptable salt thereof is fixed. Composition combined with |
WO2000027841A1 (en) * | 1998-11-06 | 2000-05-18 | Dong-A Pharmaceutical Co., Ltd. | Method of preparing sulfide derivatives |
TWI243672B (en) | 1999-06-01 | 2005-11-21 | Astrazeneca Ab | New use of compounds as antibacterial agents |
HUP0201637A3 (en) | 1999-06-07 | 2004-05-28 | Altana Pharma Ag | Novel preparation and administration form comprising an acid-labile active compound |
SE9903831D0 (en) | 1999-10-22 | 1999-10-22 | Astra Ab | Formulation of substituted benzimidazoles |
SE0000774D0 (en) | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
US6544556B1 (en) | 2000-09-11 | 2003-04-08 | Andrx Corporation | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
SE0101379D0 (en) | 2001-04-18 | 2001-04-18 | Diabact Ab | Composition that inhibits gastric acid secretion |
US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
SE0102993D0 (en) | 2001-09-07 | 2001-09-07 | Astrazeneca Ab | New self emulsifying drug delivery system |
US8101209B2 (en) | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
WO2003084518A2 (en) | 2002-04-09 | 2003-10-16 | Flamel Technologies | Oral suspension of active principle microcapsules |
ATE407674T1 (en) | 2002-04-09 | 2008-09-15 | Flamel Tech Sa | ORAL PHARMACEUTICAL FORMULATION IN THE FORM OF AN AQUEOUS SUSPENSION OF MICROCAPSULES FOR THE MODIFIED RELEASE OF AMOXICILLIN |
SE0203065D0 (en) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
CA2529984C (en) | 2003-06-26 | 2012-09-25 | Isa Odidi | Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors |
CA2540308C (en) | 2003-09-26 | 2013-08-06 | Alza Corporation | Drug coating providing high drug loading and methods for providing the same |
US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
US20060024362A1 (en) | 2004-07-29 | 2006-02-02 | Pawan Seth | Composition comprising a benzimidazole and process for its manufacture |
US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
US8541026B2 (en) | 2004-09-24 | 2013-09-24 | Abbvie Inc. | Sustained release formulations of opioid and nonopioid analgesics |
US7981908B2 (en) | 2005-05-11 | 2011-07-19 | Vecta, Ltd. | Compositions and methods for inhibiting gastric acid secretion |
US7803817B2 (en) | 2005-05-11 | 2010-09-28 | Vecta, Ltd. | Composition and methods for inhibiting gastric acid secretion |
US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
EP2007360B1 (en) | 2006-04-03 | 2014-11-26 | Isa Odidi | Controlled release delivery device comprising an organosol coat |
US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
PL2046334T3 (en) | 2006-07-25 | 2015-02-27 | Vecta Ltd | Compositions and meth0ds for inhibiting gastric acide secretion using derivatives of small dicarboxylic acids in combination with ppi |
RU2491075C2 (en) | 2006-12-22 | 2013-08-27 | Айронвуд Фармасьютикалз, Инк. | Methods and compositions for treating oesophageal disorders |
AU2009290712A1 (en) | 2008-09-09 | 2010-03-18 | Astrazeneca Ab | Method for delivering a pharmaceutical composition to patient in need thereof |
CA2764963C (en) | 2009-06-25 | 2016-11-01 | Astrazeneca Ab | Method for treating a patient at risk for developing an nsaid-associated ulcer |
WO2011080500A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
WO2011080502A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
WO2011080501A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
US20130156720A1 (en) | 2010-08-27 | 2013-06-20 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
EP2601947A1 (en) | 2011-12-05 | 2013-06-12 | Abo Bakr Mohammed Ali Al-Mehdar | Fixed-dose combination for treatment of helicobacter pylori associated diseases |
CA2860231A1 (en) | 2011-12-28 | 2013-07-04 | Pozen Inc. | Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid |
US20160015644A1 (en) | 2013-01-15 | 2016-01-21 | Ironwood Pharmaceuticals, Inc. | Gastro-retentive sustained-release oral dosage form of a bile acid sequestrant |
EP2801565B1 (en) * | 2013-05-06 | 2015-07-22 | King Saud University | Compounds for use as anti-ulcer agent and/or anti-Helicobacter pylori agent and pharmaceutical compositions thereof |
WO2016126625A1 (en) | 2015-02-03 | 2016-08-11 | Ironwood Pharmaceuticals, Inc. | Methods of treating upper gastrointestinal disorders in ppi refractory gerd |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
EP0174717B1 (en) * | 1984-07-06 | 1992-01-22 | FISONS plc | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors |
-
1985
- 1985-08-19 AU AU46409/85A patent/AU4640985A/en not_active Abandoned
- 1985-08-27 BE BE0/215506A patent/BE903128A/en not_active IP Right Cessation
- 1985-08-27 ES ES546445A patent/ES8703142A1/en not_active Expired
- 1985-08-29 GB GB08521493A patent/GB2163747B/en not_active Expired
- 1985-08-29 CH CH3709/85A patent/CH665417A5/en not_active IP Right Cessation
- 1985-08-30 AR AR85301474A patent/AR242195A1/en active
- 1985-08-30 MX MX206462A patent/MX159807A/en unknown
- 1985-08-30 DE DE3531487A patent/DE3531487C2/en not_active Expired - Fee Related
- 1985-08-30 KR KR1019850006307A patent/KR920004936B1/en not_active IP Right Cessation
- 1985-08-30 SE SE8504048A patent/SE500669C2/en unknown
- 1985-08-30 IT IT67743/85A patent/IT1189601B/en active
- 1985-08-30 FR FR858512961A patent/FR2569691B1/en not_active Expired
- 1985-08-30 BR BR8504252A patent/BR8504252A/en unknown
- 1985-08-30 NL NL8502384A patent/NL8502384A/en not_active Application Discontinuation
-
1989
- 1989-09-11 AU AU41271/89A patent/AU4127189A/en not_active Abandoned
-
1992
- 1992-11-27 AU AU29750/92A patent/AU647978B2/en not_active Ceased
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU594074B2 (en) * | 1985-08-14 | 1990-03-01 | Nippon Chemiphar Co. Ltd. | Cytoprotective agent for gastrointestinal tract |
AU619444B2 (en) * | 1986-06-02 | 1992-01-30 | Nippon Chemiphar Co. Ltd. | 2-(2-aminobenzylsulfinyl)- benzimidazole derivatives |
Also Published As
Publication number | Publication date |
---|---|
KR920004936B1 (en) | 1992-06-22 |
BE903128A (en) | 1985-12-16 |
AU4127189A (en) | 1989-12-21 |
AU2975092A (en) | 1993-01-28 |
IT8567743A0 (en) | 1985-08-30 |
SE8504048D0 (en) | 1985-08-30 |
MX159807A (en) | 1989-08-31 |
AU647978B2 (en) | 1994-03-31 |
NL8502384A (en) | 1986-03-17 |
ES546445A0 (en) | 1986-11-16 |
DE3531487A1 (en) | 1986-03-13 |
BR8504252A (en) | 1986-06-17 |
GB2163747A (en) | 1986-03-05 |
SE500669C2 (en) | 1994-08-08 |
FR2569691B1 (en) | 1989-08-04 |
FR2569691A1 (en) | 1986-03-07 |
GB8521493D0 (en) | 1985-10-02 |
ES8703142A1 (en) | 1986-11-16 |
CH665417A5 (en) | 1988-05-13 |
DE3531487C2 (en) | 1995-08-17 |
AR242195A1 (en) | 1993-03-31 |
SE8504048L (en) | 1986-03-01 |
GB2163747B (en) | 1989-02-08 |
KR860001793A (en) | 1986-03-22 |
IT1189601B (en) | 1988-02-04 |
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