AU4256496A - Transdermal system - Google Patents

Transdermal system

Info

Publication number
AU4256496A
AU4256496A AU42564/96A AU4256496A AU4256496A AU 4256496 A AU4256496 A AU 4256496A AU 42564/96 A AU42564/96 A AU 42564/96A AU 4256496 A AU4256496 A AU 4256496A AU 4256496 A AU4256496 A AU 4256496A
Authority
AU
Australia
Prior art keywords
substance
transdermal system
reservoir
skin
transfer device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU42564/96A
Inventor
Carlo Stefan Effenhauser
Andreas Manz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU4256496A publication Critical patent/AU4256496A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A transdermal system (1) for delivering a substance through the skin (2) has a reservoir (11) which stores the substance for delivery and a transfer device which in operation is connected to both the reservoir and the skin by means of passage openings. This transfer device comprises a sheet substrate (12) with up to about 30 % porosity. When the substance is delivered using an electrical field, the substrate sheet is a poor electrical conductor or essentially a nonconductor.
AU42564/96A 1994-12-09 1995-11-27 Transdermal system Abandoned AU4256496A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94810714 1994-12-09
EP94810714 1994-12-09
PCT/EP1995/004660 WO1996017648A1 (en) 1994-12-09 1995-11-27 Transdermal system

Publications (1)

Publication Number Publication Date
AU4256496A true AU4256496A (en) 1996-06-26

Family

ID=8218350

Family Applications (1)

Application Number Title Priority Date Filing Date
AU42564/96A Abandoned AU4256496A (en) 1994-12-09 1995-11-27 Transdermal system

Country Status (7)

Country Link
EP (1) EP0796128B1 (en)
JP (1) JPH10510175A (en)
AT (1) ATE177325T1 (en)
AU (1) AU4256496A (en)
CA (1) CA2205444A1 (en)
DE (1) DE59505328D1 (en)
WO (1) WO1996017648A1 (en)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE234129T1 (en) * 1996-06-18 2003-03-15 Alza Corp DEVICE FOR IMPROVING TRANSDERMAL ADMINISTRATION OF MEDICATIONS OR EXTRACTION OF BODY FLUID
DE69722414T2 (en) 1996-07-03 2004-05-19 Altea Therapeutics Corp. MULTIPLE MECHANICAL MICROPERFORATION OF SKIN OR MUCOSA
DE69718495T2 (en) * 1996-09-17 2003-11-20 Deka Products Lp SYSTEM FOR DISPOSAL OF MEDICINE BY TRANSPORT
CN1133472C (en) * 1996-12-20 2004-01-07 阿尔萨公司 Device and method for enhancing transdermal agent flux
US6527716B1 (en) 1997-12-30 2003-03-04 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
WO1999029298A2 (en) 1997-12-11 1999-06-17 Alza Corporation Device for enhancing transdermal agent flux
EP1037686B1 (en) * 1997-12-11 2005-08-17 Alza Corporation Device for enhancing transdermal agent flux
CA2313458C (en) * 1997-12-11 2007-04-17 Alza Corporation Device for enhancing transdermal agent flux
US6208893B1 (en) * 1998-01-27 2001-03-27 Genetronics, Inc. Electroporation apparatus with connective electrode template
WO1999064580A1 (en) * 1998-06-10 1999-12-16 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
GB9815820D0 (en) * 1998-07-22 1998-09-16 Secr Defence Improvements relating to micro-machining
AU8820198A (en) * 1998-08-19 2000-03-14 Gal-Ion Blaze Ltd. Method and device for topical administration of substances
CA2341446C (en) * 1998-08-31 2008-10-07 Johnson & Johnson Consumer Companies, Inc. Electrotransport device comprising blades
AU6151599A (en) * 1998-09-18 2000-04-10 University Of Utah Research Foundation Surface micromachined microneedles
JP2002532165A (en) * 1998-12-18 2002-10-02 メドトロニック ミニメド インコーポレイテッド Insert set with micro-piercing member for use with a medical device and method of using such insert set
CA2370349C (en) 1999-04-16 2013-01-29 Johnson & Johnson Consumer Companies, Inc. Electrotransport delivery system comprising internal sensors
US6379324B1 (en) * 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US20030078499A1 (en) 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
US7133717B2 (en) 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US6190367B1 (en) 1999-09-22 2001-02-20 Becton, Dickinson And Company Medical site prep device
US8465468B1 (en) 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
PT1239917E (en) 1999-12-10 2005-08-31 Alza Corp CUTANEOUS TREATMENT DEVICE FOR PROLONGED TRANSDERMIC ADMINISTRATION OF A MEDICINE
DE60024312T2 (en) 1999-12-10 2006-08-17 Alza Corp., Mountain View Transdermal drug delivery of macromolecular agents and device therefor
AU2736501A (en) * 1999-12-30 2001-07-16 Redeon, Inc. Stacked microneedle systems
EP1276426A4 (en) * 2000-03-09 2008-03-19 Nanopass Ltd Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems
US7404815B2 (en) 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US6533949B1 (en) * 2000-08-28 2003-03-18 Nanopass Ltd. Microneedle structure and production method therefor
PT1335711E (en) * 2000-09-08 2007-09-05 Alza Corp Transdermal device
JP2002085561A (en) * 2000-09-14 2002-03-26 Terumo Corp Liquid injection needle
WO2002030301A1 (en) * 2000-10-13 2002-04-18 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
HUP0303583A2 (en) 2000-10-13 2004-01-28 Alza Corp Microblade array impact applicator
DE60136951D1 (en) 2000-10-13 2009-01-22 Alza Corp MICROPHONE ELEMENT HOLDER FOR IMPACTOR
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US6821281B2 (en) 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
AU2001297823B2 (en) 2000-10-26 2005-05-12 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6855372B2 (en) 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
EP3251722B1 (en) 2001-04-20 2020-06-17 ALZA Corporation Microprojection array having a beneficial agent containing coating and method of forming the coating thereon
KR20040020889A (en) 2001-04-20 2004-03-09 알자 코포레이션 Microprojection array having a beneficial agent containing coating
US6767341B2 (en) * 2001-06-13 2004-07-27 Abbott Laboratories Microneedles for minimally invasive drug delivery
AU2002333636A1 (en) * 2001-09-14 2003-04-01 The Procter And Gamble Company Microstructures for delivering a composition cutaneously to skin using rotatable structures
JP4647863B2 (en) * 2001-09-26 2011-03-09 テルモ株式会社 Drug administration device and drug administration device
EP1480712A2 (en) * 2001-09-28 2004-12-01 BioValve Technologies, Inc. Switchable microneedle arrays and systems and methods relating to same
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
WO2003077971A2 (en) 2002-03-11 2003-09-25 Altea Therapeutics Corporation Transdermal drug delivery patch system, method of making same and method of using same
CN1655834A (en) 2002-05-06 2005-08-17 贝克顿·迪金森公司 Method and device for controlling drug pharmacokinetics
AU2003268206B2 (en) 2002-08-29 2008-12-18 Becton, Dickinson And Company Microprotrusion arrays and methods for using same to deliver substances into tissue
TW200518771A (en) 2003-06-30 2005-06-16 Alza Corp Formulations for coated microprojections containing non-volatile counterions
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
KR20060108682A (en) 2003-10-24 2006-10-18 알자 코포레이션 Pretreatment method and system for enhancing transdermal drug delivery
EP1677688A4 (en) 2003-10-28 2008-06-04 Alza Corp Method and apparatus for reducing the incidence of tobacco use
US7097631B2 (en) 2003-10-31 2006-08-29 Alza Corporation Self-actuating applicator for microprojection array
US8017145B2 (en) 2003-12-22 2011-09-13 Conopco, Inc. Exfoliating personal care wipe article containing an array of projections
EP1737357B1 (en) 2004-03-24 2019-12-11 Corium, Inc. Transdermal delivery device
JP4731931B2 (en) 2005-02-03 2011-07-27 Ｔｔｉ・エルビュー株式会社 Iontophoresis device
WO2006101146A1 (en) * 2005-03-22 2006-09-28 Transcutaneous Technologies Inc. Iontophoresis device
JP4793806B2 (en) * 2005-03-22 2011-10-12 Ｔｔｉ・エルビュー株式会社 Iontophoresis device
GB0520757D0 (en) * 2005-10-12 2005-11-23 Vuppalapati Gunasekar Delivery device
US8821446B2 (en) 2007-01-22 2014-09-02 Corium International, Inc. Applicators for microneedles
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
WO2008130587A2 (en) 2007-04-16 2008-10-30 Corium International, Inc. Solvent-cast microneedle arrays containing active
SG170622A1 (en) * 2009-10-09 2011-05-30 Nitto Denko Corp A passive drug delivery device and a method of drug delivery
EP2566501B1 (en) 2010-05-04 2019-03-13 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
CA2819859A1 (en) 2010-12-06 2012-06-14 Follica, Inc. Methods for treating baldness and promoting hair growth
BR112015014969B1 (en) 2012-12-21 2021-12-07 Corium, Inc MICROSTRUCTURE APPARATUS AND METHOD OF MANUFACTURING A MICROSTRUCTURE APPARATUS
EP2968887B1 (en) 2013-03-12 2022-05-04 Corium, Inc. Microprojection applicators
CA2903763C (en) 2013-03-15 2021-11-16 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
CN105246458B (en) 2013-03-15 2020-09-15 考里安公司 Microarrays for therapeutic agent delivery and methods of use thereof
CA2903583C (en) 2013-03-15 2021-12-28 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US10195409B2 (en) 2013-03-15 2019-02-05 Corium International, Inc. Multiple impact microprojection applicators and methods of use
EP3027263A1 (en) 2013-07-30 2016-06-08 ZP Opco, Inc. Low-profile microneedle patch applicator
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CN110664539A (en) * 2019-09-11 2020-01-10 浙江省北大信息技术高等研究院 Transdermal drug delivery patch
CN110860029B (en) * 2019-10-09 2022-04-22 杭州未名信科科技有限公司 Transdermal drug delivery patch and transdermal drug delivery method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3315665A (en) * 1963-10-11 1967-04-25 Norman A Macleod Method and apparatus for therapy of skin tissue
KR970011449B1 (en) * 1988-01-29 1997-07-11 더 리전트 오브 디 유니버시티 오브 캘리포니아 Device for iontophoretic non-invasive sampling or delivery of substances
WO1990004434A1 (en) * 1988-10-26 1990-05-03 Kabushiki Kaisya Advance Interface for electric endermism
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5156591A (en) * 1990-12-13 1992-10-20 S. I. Scientific Innovations Ltd. Skin electrode construction and transdermal drug delivery device utilizing same
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices

Also Published As

Publication number Publication date
JPH10510175A (en) 1998-10-06
EP0796128B1 (en) 1999-03-10
WO1996017648A1 (en) 1996-06-13
ATE177325T1 (en) 1999-03-15
EP0796128A1 (en) 1997-09-24
CA2205444A1 (en) 1996-06-13
DE59505328D1 (en) 1999-04-15

Similar Documents

Publication Publication Date Title
AU4256496A (en) Transdermal system
CA2074467A1 (en) Skin electrode construction and transdermal drug delivery device utilizing same
NZ313984A (en) Transcorneal drug-release system with multiple microblades and pump
GB9817662D0 (en) Substance delivery
AU8073498A (en) Liquid delivery system, heater apparatus for liquid delivery system, and vaporizer
ZA928689B (en) Drug delivery device.
AU4754696A (en) Electrotransport device having reusable controller power saver
EP1006935A4 (en) High viscosity liquid controlled delivery system
CA2155956A1 (en) Aerosol delivery apparatus
EP0714316A4 (en) Implantable drug delivery means
GR3019575T3 (en) Transdermal drug delivery device
AU3418993A (en) System for delivering an active substance for sustained release
EP0461680A3 (en) Programmable control and mounting system for transdermal drug applicator
HK1103621A1 (en) Sustained analgesia achieved with transdermal delivery of buprenorphine
IL87135A0 (en) Estradiol transdermal delivery system
ATE194296T1 (en) DEVICE FOR TRANSDERMAL DELIVERY OF MEDICATION BY IONTOPHORESIS
GR3036548T3 (en) Apparatus and method for preparing solid forms with controlled release of the active ingredient
ES8800020A1 (en) Airbed mattress including a regulated, controllable air reservoir therefor.
ES8800042A1 (en) Dispensing system with means for increasing delivery of beneficial agent from the system
EP0766974A3 (en) Blood reservoir, blood delivery instrument, and blood delivery apparatus
WO1998020869A3 (en) Formulation for electrically assisted delivery of lidocaine and epinephrine
AU6821687A (en) System for delivering drug with enhanced bioacceptability
AU3906297A (en) Electromigration injection from a microreservoir-electrode in capillary separation systems
AU4428597A (en) Iontophoretic drug delivery system, including method for activating same
HUT70705A (en) Device for vaporizing an active substance, for example insecticide or airfresheuer