AU4112497A - Glp-2 derivatives - Google Patents

Glp-2 derivatives

Info

Publication number
AU4112497A
AU4112497A AU41124/97A AU4112497A AU4112497A AU 4112497 A AU4112497 A AU 4112497A AU 41124/97 A AU41124/97 A AU 41124/97A AU 4112497 A AU4112497 A AU 4112497A AU 4112497 A AU4112497 A AU 4112497A
Authority
AU
Australia
Prior art keywords
glp
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU41124/97A
Inventor
Liselotte Bjerre Knudsen
Per Franklin Nielsen
Per Olaf Sorensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of AU4112497A publication Critical patent/AU4112497A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
AU41124/97A 1996-08-30 1997-09-01 Glp-2 derivatives Abandoned AU4112497A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DK931/96 1996-08-30
DK93196 1996-08-30
DK1259/96 1996-11-08
DK125996 1996-11-08
PCT/DK1997/000360 WO1998008872A1 (en) 1996-08-30 1997-09-01 Glp-2 derivatives

Publications (1)

Publication Number Publication Date
AU4112497A true AU4112497A (en) 1998-03-19

Family

ID=26064922

Family Applications (1)

Application Number Title Priority Date Filing Date
AU41124/97A Abandoned AU4112497A (en) 1996-08-30 1997-09-01 Glp-2 derivatives

Country Status (4)

Country Link
EP (1) EP0929576A1 (en)
JP (1) JP2000517308A (en)
AU (1) AU4112497A (en)
WO (1) WO1998008872A1 (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA65549C2 (en) 1996-11-05 2004-04-15 Елі Ліллі Енд Компані Use of glucagon-like peptides such as glp-1, glp-1 analog, or glp-1 derivative in methods and compositions for reducing body weight
JP2002504527A (en) * 1998-02-27 2002-02-12 ノボ ノルディスク アクティーゼルスカブ GLP-2 derivatives with more than 25% helical component forming partially organized micellar-like aggregates
US6451987B1 (en) 1999-03-15 2002-09-17 Novo Nordisk A/S Ion exchange chromatography of proteins and peptides
US6444788B1 (en) 1999-03-15 2002-09-03 Novo Nordisk A/S Ion exchange chromatography of GLP-1, analogs and derivatives thereof
EP1163268B1 (en) 1999-03-15 2011-05-11 Novo Nordisk A/S Ion exchange chromatographic separation of glp-1 and related peptides
US6451974B1 (en) 1999-03-17 2002-09-17 Novo Nordisk A/S Method of acylating peptides and novel acylating agents
ATE409193T1 (en) * 1999-03-17 2008-10-15 Novo Nordisk As METHOD FOR ACYLATION OF PEPTIDES AND PROTEINS
DE60134251D1 (en) 2000-09-18 2008-07-10 Sanos Bioscience As USE OF GLP-2 PEPTIDES
US7371721B2 (en) 2000-09-18 2008-05-13 Sanos Bioscience A/S Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes
WO2002040537A2 (en) * 2000-11-16 2002-05-23 Novo Nordisk A/S Analogues and derivatives of gastrin releasing peptide (grp)
US7268113B2 (en) 2001-02-02 2007-09-11 Conjuchem Biotechnologies Inc. Long lasting growth hormone releasing factor derivatives
EA006160B1 (en) 2001-02-16 2005-10-27 Конджачем, Инк. Long lasting glucagon-like peptide 2 (glp-2) for the treatment of gastrointestinal diseases and disorders
US7595172B2 (en) 2001-07-24 2009-09-29 Novo Nordisk A/S Method for making acylated polypeptides
US20030082671A1 (en) 2001-07-24 2003-05-01 Thomas Hoeg-Jensen Method for making acylated polypeptides
US7273921B2 (en) 2002-09-25 2007-09-25 Novo Nordisk A/S Method for producing acylated peptides
PL210455B1 (en) * 2002-09-25 2012-01-31 Novo Nordisk As Method for producing acylated peptides
US7411039B2 (en) 2002-10-14 2008-08-12 Novo Nordisk A/S GLP-2 compounds, formulations, and uses thereof
DE602004031927D1 (en) 2003-02-04 2011-05-05 Novo Nordisk As INJECTION DEVICE WITH ROTATABLE DOSE ADJUSTMENT DEVICE
EP1608680A2 (en) * 2003-03-24 2005-12-28 Novo Nordisk A/S Glp-2 derivatives
WO2004089985A1 (en) 2003-04-11 2004-10-21 Novo Nordisk A/S Stable pharmaceutical compositions
WO2005019261A1 (en) 2003-08-21 2005-03-03 Novo Nordisk A/S Separation of polypeptides comprising a racemized amino acid
TW200522976A (en) * 2003-09-19 2005-07-16 Novo Nordisk As Novel plasma protein affinity tags
KR101241862B1 (en) * 2003-09-19 2013-03-13 노보 노르디스크 에이/에스 Novel glp-1 derivatives
WO2005046716A1 (en) * 2003-11-13 2005-05-26 Novo Nordisk A/S Soluble pharmaceutical compositions for parenteral administration comprising a glp-1 peptide and a insulin peptide of short time action for treatment of diabetes and bulimia
US20060287221A1 (en) 2003-11-13 2006-12-21 Novo Nordisk A/S Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and an insulin peptide of short time action for treatment of diabetes and bulimia
ES2397241T3 (en) 2004-01-21 2013-03-05 Novo Nordisk Health Care Ag Conjugation of peptides by transglutaminase
WO2005082404A2 (en) * 2004-02-27 2005-09-09 Novo Nordisk A/S Glp-2 derivatives modified by lipophilic substituents
WO2006097538A1 (en) 2005-03-18 2006-09-21 Novo Nordisk A/S Extended glp-1 compounds
TWI372629B (en) 2005-03-18 2012-09-21 Novo Nordisk As Acylated glp-1 compounds
MX2008009125A (en) 2006-01-18 2008-10-23 Qps Llc Pharmaceutical compositions with enhanced stability.
KR101466933B1 (en) * 2006-07-11 2014-12-01 큐피에스 엘엘씨 Pharmaceutical compositions for sustained release delivery of peptides
ES2531934T3 (en) 2006-09-01 2015-03-20 Novo Nordisk Health Care Ag Modified glycoproteins
CA2733200A1 (en) 2008-08-06 2010-02-11 Novo Nordisk Health Care Ag Conjugated proteins with prolonged in vivo efficacy
CN102149411A (en) 2008-09-12 2011-08-10 诺沃—诺迪斯克有限公司 Method of acylating a peptide or protein
CN102292349B (en) 2009-01-22 2016-04-13 诺沃—诺迪斯克保健股份有限公司 Stable growth hormone compound
CN102612376A (en) 2009-08-06 2012-07-25 诺沃-诺迪斯克保健股份有限公司 Growth hormones with prolonged in-vivo efficacy
EP2525833A2 (en) 2010-01-22 2012-11-28 Novo Nordisk Health Care AG Stable growth hormone compounds
CN106139158A (en) 2010-01-22 2016-11-23 诺沃—诺迪斯克保健股份有限公司 The growth hormone that in vivo efficacy extends
US11045523B2 (en) 2013-04-05 2021-06-29 Novo Nordisk Healthcare Ag Formulation of growth hormone albumin-binder conjugate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69129226T2 (en) * 1990-01-24 1998-07-30 Douglas I Buckley GLP-1 ANALOG USES IN DIABETE TREATMENT
US5512549A (en) * 1994-10-18 1996-04-30 Eli Lilly And Company Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
US5990077A (en) * 1995-04-14 1999-11-23 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use

Also Published As

Publication number Publication date
EP0929576A1 (en) 1999-07-21
WO1998008872A1 (en) 1998-03-05
JP2000517308A (en) 2000-12-26

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