AU3047889A - Thiol-reactive oligonucleotide intermediates and processes for conjugation of oligonucleotides with enzymes - Google Patents

Thiol-reactive oligonucleotide intermediates and processes for conjugation of oligonucleotides with enzymes

Info

Publication number
AU3047889A
AU3047889A AU30478/89A AU3047889A AU3047889A AU 3047889 A AU3047889 A AU 3047889A AU 30478/89 A AU30478/89 A AU 30478/89A AU 3047889 A AU3047889 A AU 3047889A AU 3047889 A AU3047889 A AU 3047889A
Authority
AU
Australia
Prior art keywords
conjugation
oligonucleotides
thiol
enzymes
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU30478/89A
Inventor
Todd M. Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanogen Inc
Original Assignee
MicroProbe Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MicroProbe Corp filed Critical MicroProbe Corp
Publication of AU3047889A publication Critical patent/AU3047889A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU30478/89A 1988-01-25 1989-01-20 Thiol-reactive oligonucleotide intermediates and processes for conjugation of oligonucleotides with enzymes Abandoned AU3047889A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14825888A 1988-01-25 1988-01-25
US148258 1988-01-25

Publications (1)

Publication Number Publication Date
AU3047889A true AU3047889A (en) 1989-08-11

Family

ID=22524991

Family Applications (1)

Application Number Title Priority Date Filing Date
AU30478/89A Abandoned AU3047889A (en) 1988-01-25 1989-01-20 Thiol-reactive oligonucleotide intermediates and processes for conjugation of oligonucleotides with enzymes

Country Status (2)

Country Link
AU (1) AU3047889A (en)
WO (1) WO1989006701A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4948882A (en) * 1983-02-22 1990-08-14 Syngene, Inc. Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
US5109124A (en) * 1988-06-01 1992-04-28 Biogen, Inc. Nucleic acid probe linked to a label having a terminal cysteine
US5272077A (en) * 1989-09-12 1993-12-21 Eastman Kodak Company Method for preparing a covalent conjugate of an oligonucleotide and an enzyme
US5082780A (en) * 1989-09-12 1992-01-21 Eastman Kodak Company Oligonucleotide-enzyme conjugate that can be used as a probe in hybridization assays and polymerase chain reaction procedures
EP0422861B1 (en) * 1989-10-13 2000-05-17 Zeneca Limited Probes
GB8927365D0 (en) * 1989-12-04 1990-01-31 Ici Plc Reagent
EP0557456A4 (en) * 1990-11-14 1995-11-15 Siska Diagnostics Inc Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor
US8518409B2 (en) * 2010-05-31 2013-08-27 Imperium Biotechnologies, Inc. System for selective cell treatment using ideotypically modulated pharmacoeffectors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599303A (en) * 1983-12-12 1986-07-08 Hri Associates, Inc. Nucleic acid hybridization assay employing probes crosslinkable to target sequences
US4699876A (en) * 1984-01-27 1987-10-13 E. I. Du Pont De Nemours And Company Nonradiometric polynucleotide probes
JPS6157595A (en) * 1984-08-28 1986-03-24 Yuki Gosei Yakuhin Kogyo Kk Method of labeling polydeoxyribonucleotide or polyribonucleotide with an enzyme
EP0198207B1 (en) * 1985-03-21 1989-12-20 Molecular Diagnostics, Inc. Specific iodination of nucleic acid

Also Published As

Publication number Publication date
WO1989006701A1 (en) 1989-07-27

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