AU2668699A - Methods and compositions for modulating leptin activity - Google Patents

Methods and compositions for modulating leptin activity

Info

Publication number
AU2668699A
AU2668699A AU26686/99A AU2668699A AU2668699A AU 2668699 A AU2668699 A AU 2668699A AU 26686/99 A AU26686/99 A AU 26686/99A AU 2668699 A AU2668699 A AU 2668699A AU 2668699 A AU2668699 A AU 2668699A
Authority
AU
Australia
Prior art keywords
compositions
methods
leptin activity
modulating leptin
modulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU26686/99A
Inventor
Christian Bjorbaek
Jeffrey S. Flier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beth Israel Deaconess Medical Center Inc
Original Assignee
Beth Israel Deaconess Medical Center Inc
Beth Israel Hospital Association
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beth Israel Deaconess Medical Center Inc, Beth Israel Hospital Association filed Critical Beth Israel Deaconess Medical Center Inc
Publication of AU2668699A publication Critical patent/AU2668699A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU26686/99A 1998-02-11 1999-02-10 Methods and compositions for modulating leptin activity Abandoned AU2668699A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7432098P 1998-02-11 1998-02-11
US60074320 1998-02-11
US4427898A 1998-03-19 1998-03-19
US09044278 1998-03-19
PCT/US1999/002865 WO1999040946A2 (en) 1998-02-11 1999-02-10 Methods and compositions for modulating leptin activity

Publications (1)

Publication Number Publication Date
AU2668699A true AU2668699A (en) 1999-08-30

Family

ID=26721350

Family Applications (1)

Application Number Title Priority Date Filing Date
AU26686/99A Abandoned AU2668699A (en) 1998-02-11 1999-02-10 Methods and compositions for modulating leptin activity

Country Status (5)

Country Link
EP (1) EP1053007A2 (en)
JP (1) JP2002506004A (en)
AU (1) AU2668699A (en)
CA (1) CA2320226A1 (en)
WO (1) WO1999040946A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002521496A (en) 1998-07-28 2002-07-16 フラームス・インテルウニフェルシタイル・インスティチュート・フォール・ビオテヒノロヒー Leptin-mediated gene induction
US7078174B1 (en) 1998-12-21 2006-07-18 The Walter & Eliza Hall Institute Of Medical Research Screening methods using SOCS box-containing peptides
WO2000063357A2 (en) * 1999-04-20 2000-10-26 Beth Israel Deaconess Medical Center Methods and compositions for modulating ciliary neurotrophic factor activity
SE9903953D0 (en) * 1999-11-01 1999-11-01 Sahltech Ab New use of the jak-stat system
AUPQ614700A0 (en) 2000-03-09 2000-03-30 Walter And Eliza Hall Institute Of Medical Research, The A method and agents useful for same
AU4034601A (en) * 2000-03-09 2001-09-17 Inst Medical W & E Hall Methods of regulating cytokine signalling
ATE300611T1 (en) 2000-05-22 2005-08-15 Vlaams Interuniv Inst Biotech RECEPTOR-BASED SCREENING METHODS FOR PROTEIN INTERACTIONS
US7235629B2 (en) 2000-11-14 2007-06-26 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Functional fragment of the leptin receptor
WO2002040543A1 (en) * 2000-11-14 2002-05-23 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Functional fragment of the lectine receptor
AU2002950745A0 (en) * 2002-08-13 2002-09-12 The Walter And Eliza Hall Institute Of Medical Research A method and agents useful for same
US7423113B2 (en) 2004-08-25 2008-09-09 Vib Vzw Leptin antagonist
US7863240B2 (en) 2004-10-08 2011-01-04 Enzo Therapeutics, Inc. Methods and uses of leptin in hepatocellular carcinoma
US8969291B2 (en) 2004-10-08 2015-03-03 Enzo Therapeutics, Inc. Methods for decreasing leptin levels or activity for treating inflammation
EP1812038A1 (en) 2004-11-18 2007-08-01 VIB vzw Fibronectin iii domain as leptin receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1192248A (en) * 1995-05-30 1998-09-02 史密丝克莱恩比彻姆有限公司 Method for the detection of compounds that modulate the effects of the obese protein
WO1997044347A1 (en) * 1996-05-21 1997-11-27 Smithkline Beecham Corporation Human cis protein
EP1975234A2 (en) * 1996-11-01 2008-10-01 The Walter And Eliza Hall Institute Of Medical Research Therapeutic and diagnotics agents capable of modulating cellular responsiveness to cytokines
EP0970215A1 (en) * 1997-11-03 2000-01-12 Incyte Pharmaceuticals, Inc. Suppressor of cytokine signaling

Also Published As

Publication number Publication date
EP1053007A2 (en) 2000-11-22
JP2002506004A (en) 2002-02-26
CA2320226A1 (en) 1999-08-19
WO1999040946A3 (en) 1999-10-28
WO1999040946A2 (en) 1999-08-19

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase