AU2003299901A8 - Thrombin inhibitors - Google Patents

Thrombin inhibitors

Info

Publication number
AU2003299901A8
AU2003299901A8 AU2003299901A AU2003299901A AU2003299901A8 AU 2003299901 A8 AU2003299901 A8 AU 2003299901A8 AU 2003299901 A AU2003299901 A AU 2003299901A AU 2003299901 A AU2003299901 A AU 2003299901A AU 2003299901 A8 AU2003299901 A8 AU 2003299901A8
Authority
AU
Australia
Prior art keywords
thrombin inhibitors
thrombin
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003299901A
Other versions
AU2003299901A1 (en
Inventor
Peter D Williams
Terry A Lyle
Philip E J Sanderson
Donnette D Staas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU2003299901A1 publication Critical patent/AU2003299901A1/en
Publication of AU2003299901A8 publication Critical patent/AU2003299901A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2003299901A 2002-10-04 2003-09-30 Thrombin inhibitors Abandoned AU2003299901A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41597602P 2002-10-04 2002-10-04
US60/415,976 2002-10-04
PCT/US2003/030867 WO2004032834A2 (en) 2002-10-04 2003-09-30 Thrombin inhibitors

Publications (2)

Publication Number Publication Date
AU2003299901A1 AU2003299901A1 (en) 2004-05-04
AU2003299901A8 true AU2003299901A8 (en) 2004-05-04

Family

ID=32093790

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003299901A Abandoned AU2003299901A1 (en) 2002-10-04 2003-09-30 Thrombin inhibitors

Country Status (2)

Country Link
AU (1) AU2003299901A1 (en)
WO (1) WO2004032834A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006073167A1 (en) * 2005-01-07 2006-07-13 Ono Pharmaceutical Co., Ltd. Pyrrolidine derivatives
EP1852419A4 (en) * 2005-01-27 2009-03-04 Mitsui Chemicals Inc Method for producing fluorinated proline derivative
AU2006332945C1 (en) * 2005-12-23 2013-02-28 Wyeth Modified lysine-mimetic compounds
CN101784516B (en) 2007-06-13 2014-07-02 百时美施贵宝公司 Dipeptide analogs as coagulation factor inhibitors
AU2009263076B2 (en) * 2008-06-23 2012-07-26 Astrazeneca Ab New heterocyclic carboxamides for use as thrombin inhibitors
WO2010033701A2 (en) * 2008-09-19 2010-03-25 Genzyme Corporation Inhibitors of sphingosine kinase 1
PE20151764A1 (en) 2013-02-22 2015-12-03 Pfizer DERIVATIVES OF PIRROLO [2,3-D] PYRIMIDINE
JP6585158B2 (en) 2014-08-12 2019-10-02 ファイザー・インク Pyrrolo [2,3-d] pyrimidine derivatives useful for the inhibition of Janus kinase
CN104774160B (en) * 2015-03-09 2016-08-17 大连奇凯医药科技有限公司 A kind of preparation method of cyclopropyl fenpropathin derivative
JP2021525728A (en) * 2018-05-29 2021-09-27 オメロス コーポレーション MASP-2 inhibitor and usage
MX2022006750A (en) 2019-12-04 2022-06-14 Omeros Corp Masp-2 inhibitors and methods of use.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2436176A1 (en) * 2001-02-09 2002-08-22 Merck & Co., Inc. Thrombin inhibitors

Also Published As

Publication number Publication date
AU2003299901A1 (en) 2004-05-04
WO2004032834A2 (en) 2004-04-22
WO2004032834A3 (en) 2004-06-10

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase