AU2003280315A1 - Conjugates of interleukin-10 and polymers - Google Patents
Conjugates of interleukin-10 and polymersInfo
- Publication number
- AU2003280315A1 AU2003280315A1 AU2003280315A AU2003280315A AU2003280315A1 AU 2003280315 A1 AU2003280315 A1 AU 2003280315A1 AU 2003280315 A AU2003280315 A AU 2003280315A AU 2003280315 A AU2003280315 A AU 2003280315A AU 2003280315 A1 AU2003280315 A1 AU 2003280315A1
- Authority
- AU
- Australia
- Prior art keywords
- conjugates
- interleukin
- polymers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42668202P | 2002-11-14 | 2002-11-14 | |
US60/426,682 | 2002-11-14 | ||
PCT/DK2003/000774 WO2004044006A1 (en) | 2002-11-14 | 2003-11-11 | Conjugates of interleukin-10 and polymers |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2003280315A1 true AU2003280315A1 (en) | 2004-06-03 |
Family
ID=32313138
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003280315A Abandoned AU2003280315A1 (en) | 2002-11-14 | 2003-11-11 | Conjugates of interleukin-10 and polymers |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2003280315A1 (en) |
WO (1) | WO2004044006A1 (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2367891T3 (en) | 2000-09-29 | 2011-11-10 | Schering Corporation | INTERLEUCINA-10 PEGILADA. |
JP5105554B2 (en) | 2006-09-28 | 2012-12-26 | メルク・シャープ・アンド・ドーム・コーポレーション | Use of pegylated IL-10 to treat cancer |
EP2379115B1 (en) | 2008-12-17 | 2017-10-25 | Merck Sharp & Dohme Corp. | Mono- and di-peg il-10 production; and uses |
EP2457579A1 (en) * | 2010-11-26 | 2012-05-30 | Technische Universität Dresden | Covalently linked interleukin -10 |
BR112015026122A8 (en) | 2013-04-18 | 2020-01-21 | Armo Biosciences Inc | polyethylene glycol-yl-10 agent (peg-il-10), its use, pharmaceutical composition, sterile container and kit |
JP2016526014A (en) * | 2013-04-24 | 2016-09-01 | アルモ・バイオサイエンシーズ・インコーポレイテッド | Interleukin-10 composition and use thereof |
US9823255B2 (en) | 2013-06-17 | 2017-11-21 | Armo Biosciences, Inc. | Method for assessing protein identity and stability |
AU2014311432A1 (en) | 2013-08-30 | 2016-03-03 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
BR112016010166A2 (en) | 2013-11-11 | 2017-12-05 | Armo Biosciences Inc | Methods for Using Interleukin-10 to Treat Diseases and Disorders |
WO2015187295A2 (en) | 2014-06-02 | 2015-12-10 | Armo Biosciences, Inc. | Methods of lowering serum cholesterol |
WO2016060996A2 (en) | 2014-10-14 | 2016-04-21 | Armo Biosciences, Inc. | Interleukin-15 compositions and uses thereof |
CN107106655A (en) | 2014-10-22 | 2017-08-29 | 阿尔莫生物科技股份有限公司 | The method that disease and illness are treated using interleukin 10 |
WO2016126615A1 (en) | 2015-02-03 | 2016-08-11 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
KR20180020141A (en) | 2015-05-28 | 2018-02-27 | 아르모 바이오사이언시스 인코포레이티드 | PEGylated interleukin-10 for cancer treatment |
WO2017035232A1 (en) | 2015-08-25 | 2017-03-02 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
CA3026393C (en) * | 2016-06-22 | 2023-03-14 | Alkermes, Inc. | Compositions and methods for modulating il-10 immunostimulatory and anti-inflammatory properties |
CA3117572A1 (en) * | 2018-11-08 | 2020-05-14 | Synthorx, Inc. | Interleukin 10 conjugates and uses thereof |
CN115175704A (en) * | 2019-11-04 | 2022-10-11 | 新索思股份有限公司 | Interleukin 10 conjugates and uses thereof |
IL298471A (en) * | 2020-05-28 | 2023-01-01 | Univ Leland Stanford Junior | Engineered interleukin-10 polypeptides and uses thereof |
EP4259645A1 (en) * | 2020-12-09 | 2023-10-18 | Asher Biotherapeutics, Inc. | Fusions of mutant interleukin-10 polypeptides with antigen binding molecules for modulating immune cell function |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ502375A (en) * | 1997-07-14 | 2001-11-30 | Bolder Biotechnology Inc | The addition of non-natural cysteine derivatives to cause the protein to act as antagonists of the GH family |
AU2001231532A1 (en) * | 2000-02-11 | 2001-08-20 | Maxygen Aps | Improved interleukin 10 |
WO2001068141A2 (en) * | 2000-03-17 | 2001-09-20 | Maxygen Aps | Dispersions of polypeptide conjugates |
ES2367891T3 (en) * | 2000-09-29 | 2011-11-10 | Schering Corporation | INTERLEUCINA-10 PEGILADA. |
-
2003
- 2003-11-11 WO PCT/DK2003/000774 patent/WO2004044006A1/en not_active Application Discontinuation
- 2003-11-11 AU AU2003280315A patent/AU2003280315A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2004044006A1 (en) | 2004-05-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2003280315A1 (en) | Conjugates of interleukin-10 and polymers | |
AU2002320058A1 (en) | Magnetic-nanoparticle conjugates and methods of use | |
AU2003233887A1 (en) | Polymers their preparation and uses | |
AU2003203029A1 (en) | Improved health-related devices and methods | |
AU2003299734A1 (en) | Luminescent polymers and methods of use thereof | |
AU2002318364A1 (en) | Novel human histone deacetylases | |
AU2003214945A1 (en) | Multi-function catheter and use thereof | |
AU2003293082A1 (en) | Antioxidant-functionalized polymers | |
AU2003275311A1 (en) | Solid micro-perforators and methods of use | |
AU2002315389A1 (en) | Novel pyrazolo-and pyrrolo-pyrimidines and uses thereof | |
AU2003256217A1 (en) | New polymers and applications | |
AU2003233069A1 (en) | Gel and powder making | |
AU2003265202A1 (en) | Novel lactams and uses thereof | |
AU2002315388A1 (en) | Novel phenylamino-pyrimidines and uses thereof | |
AU2003293644A1 (en) | Moldings and preparation and uses thereof | |
AU2003232821A1 (en) | Novel phospholipases and uses thereof | |
AU2003296369A1 (en) | Imminoamines and preparation thereof | |
AU2003205381A1 (en) | Hpma-polyamine conjugates and uses therefore | |
AU2003214625A1 (en) | Histone conjugates and uses thereof | |
AU2002354070A1 (en) | Medical polymers and use thereof | |
AU2003281691A1 (en) | Furoisoquinoline derivative and use thereof | |
AU2003287802A1 (en) | Palpometer and methods of use thereof | |
AU2003231827A1 (en) | Pseudo-tissues and uses thereof | |
AU2002953223A0 (en) | Novel therapeutic molecules and uses thereof | |
AU2003302173A1 (en) | Spirotetrathiocarbamates and spirooxothiocarbamates |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |