AU2002365664A1 - Quinoline derivatives as antitumour agents - Google Patents
Quinoline derivatives as antitumour agentsInfo
- Publication number
- AU2002365664A1 AU2002365664A1 AU2002365664A AU2002365664A AU2002365664A1 AU 2002365664 A1 AU2002365664 A1 AU 2002365664A1 AU 2002365664 A AU2002365664 A AU 2002365664A AU 2002365664 A AU2002365664 A AU 2002365664A AU 2002365664 A1 AU2002365664 A1 AU 2002365664A1
- Authority
- AU
- Australia
- Prior art keywords
- quinoline derivatives
- antitumour agents
- antitumour
- agents
- quinoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01403128 | 2001-12-05 | ||
EP01403128.0 | 2001-12-05 | ||
PCT/GB2002/005496 WO2003047582A1 (en) | 2001-12-05 | 2002-12-05 | Quinoline derivatives as antitumour agents |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002365664A1 true AU2002365664A1 (en) | 2003-06-17 |
Family
ID=8183003
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002365664A Abandoned AU2002365664A1 (en) | 2001-12-05 | 2002-12-05 | Quinoline derivatives as antitumour agents |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002365664A1 (en) |
WO (1) | WO2003047582A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0215823D0 (en) | 2002-07-09 | 2002-08-14 | Astrazeneca Ab | Quinazoline derivatives |
AU2003281193A1 (en) | 2002-07-09 | 2004-01-23 | Astrazeneca Ab | Quinazoline derivatives for use in the treatment of cancer |
GB0225579D0 (en) | 2002-11-02 | 2002-12-11 | Astrazeneca Ab | Chemical compounds |
DK1562955T3 (en) | 2002-11-04 | 2008-06-02 | Astrazeneca Ab | Quinazoline derivatives as Src tyrosine kinase inhibitors |
WO2005046665A1 (en) * | 2003-11-13 | 2005-05-26 | Warner-Lambert Company Llc | Combination chemotherapy comprising a mek inhibitor and a erbb1/2 receptor inhibitor |
US7884114B2 (en) | 2007-08-15 | 2011-02-08 | Glaxo Group Limited | Compounds |
CN103539702B (en) * | 2012-07-12 | 2016-03-30 | 陕西师范大学 | The novel preparation method of N '-aryl-N, N-dimethyl carbonamidine |
CA3000988A1 (en) | 2015-10-05 | 2017-04-13 | The Trustees Of Columbia University In The City Of New York | Activators of autophagic flux and phospholipase d and clearance of protein aggregates including tau and treatment of proteinopathies |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5721237A (en) * | 1991-05-10 | 1998-02-24 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties |
UA73073C2 (en) * | 1997-04-03 | 2005-06-15 | Уайт Холдінгз Корпорейшн | Substituted 3-cyan chinolines |
US6288082B1 (en) * | 1998-09-29 | 2001-09-11 | American Cyanamid Company | Substituted 3-cyanoquinolines |
PT1117659E (en) * | 1998-09-29 | 2004-04-30 | Wyeth Corp | SUBSTITUTED CYANOCHINOLINES AS PROTEIN TYROSINE KINASE INHIBITORS |
GB9910577D0 (en) * | 1999-05-08 | 1999-07-07 | Zeneca Ltd | Chemical compounds |
US6521618B2 (en) * | 2000-03-28 | 2003-02-18 | Wyeth | 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors |
UA73993C2 (en) * | 2000-06-06 | 2005-10-17 | Астразенека Аб | Quinazoline derivatives for the treatment of tumours and a pharmaceutical composition |
CZ2003486A3 (en) * | 2000-08-21 | 2003-05-14 | Astrazeneca Ab | Quinazoline derivatives, process of their preparation and pharmaceutical preparation in which the derivatives are comprised |
-
2002
- 2002-12-05 WO PCT/GB2002/005496 patent/WO2003047582A1/en not_active Application Discontinuation
- 2002-12-05 AU AU2002365664A patent/AU2002365664A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2003047582A1 (en) | 2003-06-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |