AU2002224553A1 - Human proteases - Google Patents

Human proteases

Info

Publication number
AU2002224553A1
AU2002224553A1 AU2002224553A AU2455302A AU2002224553A1 AU 2002224553 A1 AU2002224553 A1 AU 2002224553A1 AU 2002224553 A AU2002224553 A AU 2002224553A AU 2455302 A AU2455302 A AU 2455302A AU 2002224553 A1 AU2002224553 A1 AU 2002224553A1
Authority
AU
Australia
Prior art keywords
human proteases
proteases
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002224553A
Inventor
Chandra S. Arvizu
Janice Au-Young
Yalda Azimzai
Mariah R. Baughn
Mark L. Borowsky
Neil Burford
Narinder K. Chawla
Debopriya Das
Angelo M Delegeane
Li Ding
Vicki S. Elliot
Ameena R. Gandhi
Jennifer A. Griffin
April J. A. Hafalia
Deborah A. Kallick
Liam Kearney
Farrah A. Khan
Preeti Lal
Ernestine A. Lee
Sally Lee
Terrence P. Lo
Dyung Aina M. Lu
Yan Lu
Danniel B. Nguyen
Jennifer L. Policky
Jayalaxmi Ramkumar
Madhu S. Sanjanwala
Y. Tom Tang
Kavitha Thangavelu
Stephen Todd
Catherine M. Tribouley
Junming Yang
Monique G. Yao
Henry Yue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of AU2002224553A1 publication Critical patent/AU2002224553A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
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Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE364689T1 (en) * 1999-11-18 2007-07-15 Dendreon Corp NUCLEIC ACIDS WHICH CODE FOR ENDOTHELIASES, ENDOTHELIASES, AND THEIR USE
ATE406438T1 (en) 1999-11-19 2008-09-15 Solvay Pharm Bv HUMAN HOMOLOGUE FROM THE FAMILY OF METALLOPROTEASES
US7700341B2 (en) 2000-02-03 2010-04-20 Dendreon Corporation Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
AU2001261375A1 (en) * 2000-05-09 2001-11-20 Pharmacia & Upjohn Company Human caspase-12 materials and methods
US6991916B2 (en) * 2000-07-14 2006-01-31 Pfizer Inc. Compounds for the treatment of sexual dysfunction
US7199229B2 (en) 2000-08-11 2007-04-03 Mount Sinai Hospital Kallikrein gene
AU2001294181A1 (en) * 2000-10-05 2002-04-15 Takeda Chemical Industries Ltd. Novel protein, process for producing the same and use thereof
CA2426588A1 (en) * 2000-10-26 2002-07-18 Curagen Corporation Novel human proteins, polynucleotides encoding them and methods of using the same
WO2002072786A2 (en) * 2001-03-13 2002-09-19 Corvas International, Inc. Nucleic acid molecules encoding a transmembrane serine protease 7, the encoded polypeptides and methods based thereon
JP2004535166A (en) * 2001-03-22 2004-11-25 デンドレオン・サンディエゴ・リミテッド・ライアビリティ・カンパニー Nucleic acid molecule encoding serine protease CVSP14, encoded polypeptide and methods based thereon
EP1379637A4 (en) 2001-03-27 2005-04-06 Dendreon Corp Nucleic acid molecules encoding a transmembran serine protease 9, the encoded polypeptides and methods based thereon
WO2002092841A2 (en) 2001-05-14 2002-11-21 Dendreon San Diego Llc Nucleic acid molecules encoding a transmembrane serine protease 10, the encoded polypeptides and methods based thereon
WO2002095018A1 (en) * 2001-05-22 2002-11-28 Bayer Healthcare Ag Regulation of human zinc carboxypeptidase b-like protein
US20030143219A1 (en) * 2001-10-09 2003-07-31 Madison Edwin L Nucleic acid molecules encoding a transmembrane serine protease 25, the encoded polypeptides and methods based thereon
WO2003044179A2 (en) * 2001-11-20 2003-05-30 Dendreon San Diego Llc Nucleic acid molecules encoding serine protease 17, the encoded polypeptides and methods based thereon
US7902185B2 (en) * 2002-06-03 2011-03-08 Als Therapy Development Foundation, Inc. Treatment of neurodegenerative diseases using proteasome modulators
AU2003247776A1 (en) * 2002-07-02 2004-01-23 Dendreon Corporation Serine protease 16
US20040014131A1 (en) * 2002-07-09 2004-01-22 Pfizer Inc. Assay methods

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4873191A (en) * 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
DE3301833A1 (en) * 1983-01-20 1984-07-26 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig METHOD FOR SIMULTANEOUS SYNTHESIS OF SEVERAL OLIGONOCLEOTIDES IN A SOLID PHASE
US4713326A (en) * 1983-07-05 1987-12-15 Molecular Diagnostics, Inc. Coupling of nucleic acids to solid support by photochemical methods
US4594595A (en) * 1984-04-18 1986-06-10 Sanders Associates, Inc. Circular log-periodic direction-finder array
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
DE3781017T2 (en) * 1986-05-06 1993-03-18 Univ Leland Stanford Junior CYTOTOXIC COMPOSITION OF "KILLER" CELLS.
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5700637A (en) * 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US5272057A (en) * 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) * 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5424186A (en) * 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5252743A (en) * 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
US6150584A (en) * 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US6075181A (en) * 1990-01-12 2000-06-13 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
US5877397A (en) * 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5605793A (en) * 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5837458A (en) * 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
AU3003395A (en) * 1994-07-15 1996-02-16 Cephalon, Inc. Active calpain expressed by baculovirus
US5908635A (en) * 1994-08-05 1999-06-01 The United States Of America As Represented By The Department Of Health And Human Services Method for the liposomal delivery of nucleic acids
US5556752A (en) * 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
EP0717110A1 (en) * 1994-11-22 1996-06-19 Association Francaise Contre Les Myopathies LGMD gene
US5948767A (en) * 1994-12-09 1999-09-07 Genzyme Corporation Cationic amphiphile/DNA complexes
US5494595A (en) * 1994-12-30 1996-02-27 Huntsman Corporation Oil soluble polyethers
WO1998035988A1 (en) * 1997-02-14 1998-08-20 Zeneca Limited Proteins
CA2234418A1 (en) * 1997-06-24 1998-12-24 Smithkline Beecham Corporation Human afc1
EP1036086A1 (en) * 1997-10-30 2000-09-20 Human Genome Sciences, Inc. Caspase-14 polypeptides
EP1059353B1 (en) * 1998-03-02 2006-04-26 Senju Pharmaceutical Co., Ltd. Novel calpain and dna encoding the same
AU1450900A (en) * 1998-10-21 2000-05-08 Arch Development Corporation Methods of treatment of type 2 diabetes
CA2388511A1 (en) * 1999-11-04 2001-05-10 Incyte Genomics, Inc. Tissue specific genes of diagnostic import

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