AU2002219935A1 - Polyalkylene glycol viscosity-enhancing polymeric formulations - Google Patents

Polyalkylene glycol viscosity-enhancing polymeric formulations

Info

Publication number
AU2002219935A1
AU2002219935A1 AU2002219935A AU1993502A AU2002219935A1 AU 2002219935 A1 AU2002219935 A1 AU 2002219935A1 AU 2002219935 A AU2002219935 A AU 2002219935A AU 1993502 A AU1993502 A AU 1993502A AU 2002219935 A1 AU2002219935 A1 AU 2002219935A1
Authority
AU
Australia
Prior art keywords
viscosity
tissue
polyalkylene glycol
mixture
hyaluronic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002219935A
Inventor
Luis Z Avila
Peter K. Jarrett
Hildegard Kramer
Michael C. Philbrook
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Focal Inc
Original Assignee
Focal Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22960435&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2002219935(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Focal Inc filed Critical Focal Inc
Publication of AU2002219935A1 publication Critical patent/AU2002219935A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/041Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043Mixtures of macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02Polyalkylene oxides

Abstract

Hyaluronic acid and polyalkylene glycol (PAG) based materials have been found to exhibit a synergistic interaction, in which the viscosity of the mixture is more than twice as high as the viscosity expected from the viscosity of the individual components. The mixture otherwise has similar properties to those of its constituents, and in particular will crosslink to form covalently crosslinked gels if the PEG carries crosslinkable groups. The viscous formulation adheres well to tissue, and has applications as a tissue sealant and in tissue coating, prevention of adhesions, cell immobilization, regeneration of cartilage, bone and other tissue, as well as in controlled delivery of hyaluronic acid to sites in the body. Related materials exhibit similar effects.
AU2002219935A 2000-11-28 2001-11-28 Polyalkylene glycol viscosity-enhancing polymeric formulations Abandoned AU2002219935A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25347700P 2000-11-28 2000-11-28
US60/253,477 2000-11-28
PCT/US2001/044769 WO2002044276A2 (en) 2000-11-28 2001-11-28 Polyalkylene glycol viscosity-enhancing polymeric formulations

Publications (1)

Publication Number Publication Date
AU2002219935A1 true AU2002219935A1 (en) 2002-06-11

Family

ID=22960435

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002219935A Abandoned AU2002219935A1 (en) 2000-11-28 2001-11-28 Polyalkylene glycol viscosity-enhancing polymeric formulations

Country Status (8)

Country Link
US (1) US7074424B2 (en)
EP (1) EP1370610B1 (en)
JP (1) JP2004514778A (en)
AT (1) ATE407975T1 (en)
AU (1) AU2002219935A1 (en)
CA (1) CA2430130A1 (en)
DE (1) DE60135784D1 (en)
WO (1) WO2002044276A2 (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR039744A1 (en) * 2002-06-26 2005-03-09 Alza Corp METHODS AND DOSAGE FORMS TO INCREASE THE SOLUBILITY OF PHARMACOS COMPOSITIONS FOR CONTROLLED ADMINISTRATION
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
MXPA05001184A (en) * 2002-07-29 2005-09-12 Johnson & Johnson Formulations and dosage forms for controlled delivery of topiramate.
US6992127B2 (en) * 2002-11-25 2006-01-31 Ast Products, Inc. Polymeric coatings containing a pH buffer agent
US20060235114A1 (en) * 2003-07-28 2006-10-19 Teijin Limited Temperature-responsive hydrogel
MXPA06001548A (en) * 2003-08-06 2006-09-04 Johnson & Johnson Uniform delivery of topiramate over prolonged period of time with enhanced dispersion formulation.
US20050136108A1 (en) * 2003-08-22 2005-06-23 Yam Noymi V. Stepwise delivery of topiramate over prolonged period of time
JP2007517061A (en) * 2003-12-29 2007-06-28 アルザ・コーポレーシヨン Novel pharmaceutical composition and dosage form
US20050175696A1 (en) * 2003-12-29 2005-08-11 David Edgren Drug granule coatings that impart smear resistance during mechanical compression
EP1701708A2 (en) * 2003-12-29 2006-09-20 Alza Corporation Novel drug compositions and dosage forms of topiramate
MXPA06013056A (en) * 2004-05-07 2007-04-17 S K Pharmaceuticals Inc Stabilized hyaluronan preparations and related methods.
US8288362B2 (en) 2004-05-07 2012-10-16 S.K. Pharmaceuticals, Inc. Stabilized glycosaminoglycan preparations and related methods
WO2005115489A2 (en) * 2004-05-24 2005-12-08 Genzyme Corporation Adherent polymeric compositions
US20060140988A1 (en) * 2004-12-23 2006-06-29 Guohua Chen Visco-supplement composition and methods
US8414907B2 (en) * 2005-04-28 2013-04-09 Warsaw Orthopedic, Inc. Coatings on medical implants to guide soft tissue healing
US9119901B2 (en) 2005-04-28 2015-09-01 Warsaw Orthopedic, Inc. Surface treatments for promoting selective tissue attachment to medical impants
AU2006287485B2 (en) * 2005-09-07 2012-07-12 Amo Regional Holdings Bi-modal hyaluronate solution
ES2285910B1 (en) * 2005-09-08 2008-12-16 Vicente Tormo Maicas PROCEDURE FOR THE ELABORATION OF THE FORMULA OF SODIUM HYALURONATE FOR THE HEALING AND CICATRIZATION OF WOUNDS.
AU2006321912B2 (en) * 2005-12-06 2012-07-12 Covidien Lp Carbodiimide crosslinking of functionalized polethylene glycols
GB0608359D0 (en) * 2006-04-28 2006-06-07 Johnson Matthey Plc Catalyst additives
WO2008011836A2 (en) * 2006-07-25 2008-01-31 Osmotica Corp. Ophthalmic solutions
US20090105561A1 (en) * 2007-10-17 2009-04-23 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Medical or veterinary digestive tract utilization systems and methods
MX2011007462A (en) 2009-01-13 2011-08-03 Pharmasurgics In Sweden Ab Hylauronic acid containing compositions for treatment of wounds, scars, post-surgical adhesion formation.
BR112012026372A2 (en) * 2010-04-16 2016-08-02 Apatech Ltd biocompatible material, method for making a material, and resorbable polymer matrix
KR20130108996A (en) * 2010-05-07 2013-10-07 유니버시티 오브 노스캐롤라이나 앳 채플 힐 Method of engrafting cells from solid tissues
CN102988274B (en) * 2010-09-08 2015-01-28 上海市肿瘤研究所 Sustained-release blood vessel embolic gel used for treating tumor, and preparation method thereof
TWI413535B (en) * 2010-12-09 2013-11-01 Yung Kai Lin Thremosensitivity hydrogel for tissue engineering and use thereof
TWI544922B (en) 2011-05-19 2016-08-11 愛爾康研究有限公司 High concentration olopatadine ophthalmic composition
CA2841795C (en) 2011-07-05 2020-09-15 The Research Foundation For The State University Of New York Compositions and methods for spinal disc repair and other surgical and non-surgical indications
KR101269423B1 (en) * 2011-12-22 2013-05-30 오스템임플란트 주식회사 Hydrogel with controllable biodegradation behavior and the manufacturing method thereof
WO2014028209A1 (en) * 2012-08-14 2014-02-20 The Trustees Of The University Of Pennsylvania Stabilizing shear-thinning hydrogels
CA3097530A1 (en) 2018-04-19 2019-10-24 Poly-Med, Inc. Macromers and compositions for photocuring processes
WO2020232005A1 (en) * 2019-05-13 2020-11-19 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Polymer-based implant for retinal therapy and methods of making and using the same
US20210094226A1 (en) * 2019-09-26 2021-04-01 The Curators Of The University Of Missouri Oxidation polymerization additive manufacturing
CN116077731A (en) * 2021-11-05 2023-05-09 重庆医科大学附属口腔医院 Tissue repair material based on giant salamander skin secretion and application thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3325472A (en) 1964-06-18 1967-06-13 Mortimer D Sackler Polycyclohexose-polyoxyethyleneglycol suppository bases
NO169637C (en) 1983-10-11 1992-07-22 Fidia Spa PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE HYALURONIC ACID FRACTIONS
US4629623A (en) * 1984-06-11 1986-12-16 Biomatrix, Inc. Hyaluronate-poly (ethylene oxide) compositions and cosmetic formulations thereof
US5068225A (en) 1987-05-04 1991-11-26 Mdr Group, Inc. Viscoelastic fluid for use in surgery and other therapies and method of using same
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5143724A (en) 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
AU709527B2 (en) 1995-03-23 1999-09-02 Board Of Regents, The University Of Texas System Redox and photoinitiator systems for priming for improved adherence of gels to substrates
ZA978537B (en) * 1996-09-23 1998-05-12 Focal Inc Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
AU6769098A (en) * 1997-03-20 1998-10-12 Focal, Inc. Biodegradable tissue retractor
US5906997A (en) * 1997-06-17 1999-05-25 Fzio Med, Inc. Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions
FR2780730B1 (en) * 1998-07-01 2000-10-13 Corneal Ind INJECTABLE BIPHASIC COMPOSITIONS, ESPECIALLY USEFUL IN RESTORATIVE AND AESTHETIC SURGERIES
EP1223986A2 (en) 1999-06-11 2002-07-24 Shearwater Corporation Hydrogels derived from chitosan and poly(ethylene glycol)
US6288043B1 (en) * 1999-06-18 2001-09-11 Orquest, Inc. Injectable hyaluronate-sulfated polysaccharide conjugates
US6685883B2 (en) 1999-08-27 2004-02-03 Tetra Laval Holdings & Finance S.A. Method and unit for sterilizing packaging sheet material for manufacturing sealed packages of pourable food products

Also Published As

Publication number Publication date
ATE407975T1 (en) 2008-09-15
DE60135784D1 (en) 2008-10-23
WO2002044276A2 (en) 2002-06-06
EP1370610A2 (en) 2003-12-17
CA2430130A1 (en) 2002-06-06
JP2004514778A (en) 2004-05-20
US7074424B2 (en) 2006-07-11
US20020127196A1 (en) 2002-09-12
WO2002044276A3 (en) 2003-03-20
EP1370610B1 (en) 2008-09-10

Similar Documents

Publication Publication Date Title
AU2002219935A1 (en) Polyalkylene glycol viscosity-enhancing polymeric formulations
JP2007500027A (en) Composite matrix for biomedical use
EP2181704A3 (en) Drug delivery from rapid gelling polymer composition
ES2946738T3 (en) Fast acting dry sealant and methods of use and manufacture
AU2007240613B2 (en) Polymeric compositions and methods of making and using thereof
US5639796A (en) Injectable medical composition and method of use
WO2000062827A3 (en) Rapid gelling biocompatible polymer composition
AU2008243174B2 (en) Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
CA2239775A1 (en) Crosslinked polymer compositions and methods for their use
MXPA03000190A (en) Composition for delivery of hematopoietic growth factor.
WO1998027963A3 (en) Gel composition and methods
AU9036598A (en) Methods and compositions to prevent formation of adhesions in biological tissues
CA2276661A1 (en) Personal wash liquid composition comprising low viscosity oils pre-thickened by non-antifoaming hydrophobic polymers
CA2550718A1 (en) Cohesive gels from cross-linked hyaluronan and/or hylan, their preparation and use
PT2093245E (en) Biocompatible polymer device
WO2013110056A1 (en) Biomaterials comprising hyaluronic acid binding peptides and bifunctional biopolymer molecules for hyaluronic acid retention and tissue engineering applications
US8747870B2 (en) Polymeric compositions and methods of making and using thereof
AU2001266033A1 (en) Formulation based on heparin, glycosaminoglycan or heparinoid, use of the formulation and the formulation base
BR9809483A (en) Crosslinking composition, process for making it, and use thereof.
AU2001269178A1 (en) Use as thickeners in cosmetics of neutralized copolymers comprising weak acid units and strong acid units, and cosmetic compositions comprising same
Biscari et al. Antibacterial Broad‐Spectrum Dendritic/Gellan Gum Hybrid Hydrogels with Rapid Shape‐Forming and Self‐Healing for Wound Healing Application
EP3965842A1 (en) Medical compositions based on crosslinkable hydrophilic polymers
Jung et al. Preparation and properties of PEG & PHEMA hydrogels containing sulfonated PEG graft