AU2001259215A1 - Human anti-cd40 antibodies and methods of making and using same - Google Patents

Human anti-cd40 antibodies and methods of making and using same

Info

Publication number
AU2001259215A1
AU2001259215A1 AU2001259215A AU5921501A AU2001259215A1 AU 2001259215 A1 AU2001259215 A1 AU 2001259215A1 AU 2001259215 A AU2001259215 A AU 2001259215A AU 5921501 A AU5921501 A AU 5921501A AU 2001259215 A1 AU2001259215 A1 AU 2001259215A1
Authority
AU
Australia
Prior art keywords
antibodies
making
methods
same
human anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001259215A
Inventor
Xingjie Chen
Toshifumi Mikayama
Stephen P. Schoenberger
Nobuaki Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
La Jolla Institute for Allergy and Immunology
Original Assignee
Kirin Pharma USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Pharma USA Inc filed Critical Kirin Pharma USA Inc
Publication of AU2001259215A1 publication Critical patent/AU2001259215A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95
AU2001259215A 2000-04-28 2001-04-27 Human anti-cd40 antibodies and methods of making and using same Abandoned AU2001259215A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20060100P 2000-04-28 2000-04-28
US60200601 2000-04-28
PCT/US2001/013672 WO2001083755A2 (en) 2000-04-28 2001-04-27 Human anti-cd40 antibodies and methods of making and using same

Publications (1)

Publication Number Publication Date
AU2001259215A1 true AU2001259215A1 (en) 2001-11-12

Family

ID=22742393

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001259215A Abandoned AU2001259215A1 (en) 2000-04-28 2001-04-27 Human anti-cd40 antibodies and methods of making and using same

Country Status (3)

Country Link
AU (1) AU2001259215A1 (en)
TW (1) TWI264467B (en)
WO (1) WO2001083755A2 (en)

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US5397703A (en) 1992-07-09 1995-03-14 Cetus Oncology Corporation Method for generation of antibodies to cell surface molecules
US20030059427A1 (en) * 2000-04-28 2003-03-27 Force Walker R. Isolation and characterization of highly active anti-CD40 antibody
US7063845B2 (en) 2000-04-28 2006-06-20 Gemini Science, Inc. Human anti-CD40 antibodies
DE60143535D1 (en) * 2000-10-02 2011-01-05 Novartis Vaccines & Diagnostic HUMAN ANTIBODIES AGAINST CD40
MXPA03003919A (en) * 2000-11-03 2003-09-25 Univ South Florida Methods and compositions for stimulating cd45 and thereby suppressing microglial activation associated with alzheimer s disease.
CA2658221C (en) 2001-04-27 2012-11-27 Kyowa Hakko Kirin Co., Ltd. Anti-cd40 monoclonal antibody
WO2003029296A1 (en) * 2001-10-02 2003-04-10 Chiron Corporation Human anti-cd40 antibodies
WO2003028809A1 (en) * 2001-10-02 2003-04-10 Chiron Corporation Methods of therapy for b-cell malignancies
AR039067A1 (en) * 2001-11-09 2005-02-09 Pfizer Prod Inc ANTIBODIES FOR CD40
WO2003045978A2 (en) * 2001-11-26 2003-06-05 Chiron Corporation Antagonist anti-cd40 monoclonal antibody therapy for multiple sclerosis treatment
EP2075256A2 (en) 2002-01-14 2009-07-01 William Herman Multispecific binding molecules
EP1694360B1 (en) * 2003-11-04 2010-08-04 Novartis Vaccines and Diagnostics, Inc. Use of antagonist anti-cd40 antibodies for treatment of autoimmune and inflammatory diseases and organ transplant rejection
EP2236172A1 (en) * 2003-11-04 2010-10-06 Novartis Vaccines and Diagnostics, Inc. Combination therapy comprising anti-CD20 and anti-CD40 antibodies for the treatment of B cell-related cancers
ES2346978T3 (en) 2003-11-04 2010-10-22 Novartis Vaccines And Diagnostics, Inc. USE OF ANTI-CD40 ANTIGONIST MONOCLONANT ANTIBODIES FOR THE TREATMENT OF MULTIPLE MYELOMA.
US8277810B2 (en) 2003-11-04 2012-10-02 Novartis Vaccines & Diagnostics, Inc. Antagonist anti-CD40 antibodies
WO2005044304A2 (en) * 2003-11-04 2005-05-19 Chiron Corporation Use of antagonist anti-cd40 antibodies for treatment of chronic lymphocytic leukemia
WO2006073443A2 (en) * 2004-04-27 2006-07-13 Novartis Vaccines And Diagnostics, Inc. Antagonist anti-cd40 monoclonal antibodies and methods for their use
CN101325970B (en) 2005-11-01 2013-08-14 诺华有限公司 Uses of anti-cd40 antibodies
EA018301B1 (en) 2006-04-21 2013-07-30 Новартис Аг Pharmaceutical compositions comprising antagonist monoclonal anti-cd40 antibody and use thereof
CN101910414B (en) 2007-11-07 2016-01-13 健泰科生物技术公司 For assessment of the method and composition of the responsiveness of B cell lymphoma antagonism CD40 Antybody therapy
WO2010104747A2 (en) 2009-03-10 2010-09-16 Baylor Research Institute Antigen presenting cell targeted vaccines
AU2010222928B2 (en) 2008-07-16 2012-11-29 Baylor Research Institute Antigen presenting cell targeted vaccines
JP2012511014A (en) * 2008-12-05 2012-05-17 エイエルエス・セラピー・デベロップメント・インスティテュート Methods for treating neurodegenerative diseases
US9044459B2 (en) 2008-12-05 2015-06-02 Als Therapy Development Institute Method for the treatment of neurodegenerative diseases
DK2406286T3 (en) 2009-03-10 2016-08-22 Baylor Res Inst Anti-cd40 antibodies and uses thereof
MX2011010938A (en) 2009-04-18 2012-01-12 Genentech Inc Methods for assessing responsiveness of b-cell lymphoma to treatment with anti-cd40 antibodies.
AR083847A1 (en) 2010-11-15 2013-03-27 Novartis Ag FC VARIANTS (CONSTANT FRAGMENT) SILENCERS OF ANTI-CD40 ANTIBODIES
WO2012135132A1 (en) 2011-03-25 2012-10-04 Baylor Research Institute Compositions and methods to immunize against hepatitis c virus
GB201115280D0 (en) * 2011-09-05 2011-10-19 Alligator Bioscience Ab Antibodies, uses and methods
GB201322583D0 (en) * 2013-12-19 2014-02-05 Alligator Bioscience Ab Antibodies
JP7037884B2 (en) 2014-01-13 2022-03-17 ベイラー リサーチ インスティテュート New vaccines for HPV and HPV-related diseases
JP6654187B2 (en) 2014-08-12 2020-02-26 アリゲーター・バイオサイエンス・アーベー Combination therapy using anti-CD40 antibody
MA41459A (en) 2015-02-03 2017-12-12 Als Therapy Development Inst ANTI-CD40L ANTIBODIES AND METHODS FOR TREATING CD40L ILLNESSES OR DISORDERS
EP3355921A4 (en) 2015-09-30 2019-05-22 Janssen Biotech, Inc. Antagonistic antibodies specifically binding human cd40 and methods of use
MA45488A (en) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh CELL CULTURE PROCESSES, KITS AND APPARATUS
BR112018008891A8 (en) 2015-11-03 2019-02-26 Janssen Biotech Inc antibodies that specifically bind to pd-1 and tim-3 and their uses
JP7461741B2 (en) 2016-06-20 2024-04-04 カイマブ・リミテッド Anti-PD-L1 and IL-2 Cytokines
AU2017308734A1 (en) 2016-08-12 2019-02-14 Janssen Biotech, Inc. Fc engineered anti-TNFR superfamily member antibodies having enhanced agonistic activity and methods of using them
SG11201900746RA (en) 2016-08-12 2019-02-27 Janssen Biotech Inc Engineered antibodies and other fc-domain containing molecules with enhanced agonism and effector functions
KR102606210B1 (en) 2017-04-27 2023-11-24 주노 테라퓨틱스 게엠베하 Oligomeric particle reagents and methods of use thereof
WO2018217918A2 (en) 2017-05-24 2018-11-29 Als Therapy Development Institute Therapeutic anti-cd40 ligand antibodies
KR102198998B1 (en) * 2017-06-01 2021-01-07 서울대학교 산학협력단 Novel anti-cd40 antibodies and uses thereof
US10610585B2 (en) 2017-09-26 2020-04-07 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and compositions for treating and preventing HIV
US11672826B2 (en) 2018-08-30 2023-06-13 HCW Biologics, Inc. Methods of treating aging-related disorders
CN113365663A (en) 2018-08-30 2021-09-07 Hcw生物科技公司 Single-chain chimeric polypeptides and uses thereof
WO2020047299A1 (en) 2018-08-30 2020-03-05 HCW Biologics, Inc. Multi-chain chimeric polypeptides and uses thereof
CN109678959B (en) * 2019-02-22 2020-12-08 北京免疫方舟医药科技有限公司 anti-CD 40 antibodies and uses thereof
CN114269903A (en) 2019-06-21 2022-04-01 Hcw生物科技公司 Multi-chain chimeric polypeptides and uses thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0945465T3 (en) * 1992-07-09 2007-01-15 Novartis Vaccines & Diagnostic Antagonistic monoclonal antibodies to human CD40
ES2211884T3 (en) * 1993-10-01 2004-07-16 Immunex Corporation ANTIBODIES AGAINST CD40.
CA2219361C (en) * 1995-04-27 2012-02-28 Abgenix, Inc. Human antibodies derived from immunized xenomice
EP0823941A4 (en) * 1995-04-28 2001-09-19 Abgenix Inc Human antibodies derived from immunized xenomice
WO2000000156A2 (en) * 1998-06-26 2000-01-06 Trustees Of Dartmouth College Methods for modulating immunological responses by targeting antigen to apcs in conjuction with anti-cd40 ligands

Also Published As

Publication number Publication date
WO2001083755A2 (en) 2001-11-08
WO2001083755A3 (en) 2002-05-23
TWI264467B (en) 2006-10-21

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