AU2000279625A1 - Blood mmp-3 level-lowering agent containing il-6 antgonist as the active ingredient - Google Patents

Blood mmp-3 level-lowering agent containing il-6 antgonist as the active ingredient

Info

Publication number
AU2000279625A1
AU2000279625A1 AU2000279625A AU7962500A AU2000279625A1 AU 2000279625 A1 AU2000279625 A1 AU 2000279625A1 AU 2000279625 A AU2000279625 A AU 2000279625A AU 7962500 A AU7962500 A AU 7962500A AU 2000279625 A1 AU2000279625 A1 AU 2000279625A1
Authority
AU
Australia
Prior art keywords
antgonist
level
active ingredient
agent containing
lowering agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2000279625A
Inventor
Norihiro Nishimoto
Kenichi Obata
Yasunori Okada
Kazuyuki Yoshizaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Kyowa Pharma Chemical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Fuji Yakuhin Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11736636&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2000279625(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chugai Pharmaceutical Co Ltd, Fuji Yakuhin Kogyo KK filed Critical Chugai Pharmaceutical Co Ltd
Publication of AU2000279625A1 publication Critical patent/AU2000279625A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2000279625A 2000-10-27 2000-10-27 Blood mmp-3 level-lowering agent containing il-6 antgonist as the active ingredient Abandoned AU2000279625A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2000/007604 WO2002036165A1 (en) 2000-10-27 2000-10-27 Blood mmp-3 level-lowering agent containing il-6 antgonist as the active ingredient

Publications (1)

Publication Number Publication Date
AU2000279625A1 true AU2000279625A1 (en) 2002-05-15

Family

ID=11736636

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2000279625A Abandoned AU2000279625A1 (en) 2000-10-27 2000-10-27 Blood mmp-3 level-lowering agent containing il-6 antgonist as the active ingredient

Country Status (4)

Country Link
US (1) US20060292147A1 (en)
JP (1) JP4889187B2 (en)
AU (1) AU2000279625A1 (en)
WO (1) WO2002036165A1 (en)

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CZ297083B6 (en) * 1998-03-17 2006-09-13 Chugai Seiyaku Kabushiki Kaisha Agent for prevention and treatment of inflammatory intestinal disease containing IL-6 antagonist as active component
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BRPI0617664B8 (en) * 2005-10-21 2021-05-25 Chugai Pharmaceutical Co Ltd use of an antibody recognizing IL-6 for the production of a pharmaceutical composition to treat myocardial infarction or suppress left ventricular remodeling after myocardial infarction
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JP5624276B2 (en) * 2006-03-31 2014-11-12 中外製薬株式会社 Methods for controlling blood kinetics of antibodies
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US8178101B2 (en) 2007-05-21 2012-05-15 Alderbio Holdings Inc. Use of anti-IL-6 antibodies having specific binding properties to treat cachexia
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US9701747B2 (en) 2007-05-21 2017-07-11 Alderbio Holdings Llc Method of improving patient survivability and quality of life by anti-IL-6 antibody administration
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US8062864B2 (en) * 2007-05-21 2011-11-22 Alderbio Holdings Llc Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
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CN102256623A (en) * 2008-06-05 2011-11-23 独立行政法人国立癌症研究中心 Neuroinvasion inhibitor
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US8992920B2 (en) 2008-11-25 2015-03-31 Alderbio Holdings Llc Anti-IL-6 antibodies for the treatment of arthritis
US9452227B2 (en) 2008-11-25 2016-09-27 Alderbio Holdings Llc Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
US8323649B2 (en) 2008-11-25 2012-12-04 Alderbio Holdings Llc Antibodies to IL-6 and use thereof
US8337847B2 (en) 2008-11-25 2012-12-25 Alderbio Holdings Llc Methods of treating anemia using anti-IL-6 antibodies
US9212223B2 (en) 2008-11-25 2015-12-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
US8420089B2 (en) 2008-11-25 2013-04-16 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
TWI544077B (en) 2009-03-19 2016-08-01 Chugai Pharmaceutical Co Ltd Antibody constant region change body
EP2409991B1 (en) 2009-03-19 2017-05-03 Chugai Seiyaku Kabushiki Kaisha Antibody constant region variant
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US20120183539A1 (en) * 2009-07-31 2012-07-19 Shin Maeda Cancer Metastasis Inhibitor
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US9775921B2 (en) 2009-11-24 2017-10-03 Alderbio Holdings Llc Subcutaneously administrable composition containing anti-IL-6 antibody
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EP3009518B1 (en) 2013-06-11 2020-08-12 National Center of Neurology and Psychiatry Method for predicting post-therapy prognosis of relapsing-remitting multiple sclerosis (rrms) patient, and method for determining applicability of novel therapy
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US9017678B1 (en) 2014-07-15 2015-04-28 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
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US11142587B2 (en) 2015-04-01 2021-10-12 Chugai Seiyaku Kabushiki Kaisha Method for producing polypeptide hetero-oligomer
PL3299810T3 (en) 2015-05-19 2021-12-13 National Center Of Neurology And Psychiatry Method for determining application of novel therapy to multiple sclerosis (ms) patient
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AU2016381992B2 (en) 2015-12-28 2024-01-04 Chugai Seiyaku Kabushiki Kaisha Method for promoting efficiency of purification of Fc region-containing polypeptide
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JP7185884B2 (en) 2017-05-02 2022-12-08 国立研究開発法人国立精神・神経医療研究センター METHOD FOR PREDICTING AND DETERMINING THERAPEUTIC EFFECT OF IL-6 AND NEUTROPHIL-RELATED DISEASE
WO2019078344A1 (en) 2017-10-20 2019-04-25 学校法人兵庫医科大学 Anti-il-6 receptor antibody-containing medicinal composition for preventing post-surgical adhesion
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CA2284271C (en) * 1997-03-21 2012-05-08 Chugai Seiyaku Kabushiki Kaisha A preventive or therapeutic agent for sensitized t cell-mediated diseases comprising il-6 antagonist as an active ingredient
US20020187150A1 (en) * 1997-08-15 2002-12-12 Chugai Seiyaku Kabushiki Kaisha Preventive and/or therapeutic agent for systemic lupus erythematosus comprising anti-IL-6 receptor antibody as an active ingredient
CZ297083B6 (en) * 1998-03-17 2006-09-13 Chugai Seiyaku Kabushiki Kaisha Agent for prevention and treatment of inflammatory intestinal disease containing IL-6 antagonist as active component
UA80091C2 (en) * 2001-04-02 2007-08-27 Chugai Pharmaceutical Co Ltd Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist
EP1499305A2 (en) * 2002-04-12 2005-01-26 Pfizer Japan Inc. Use of ep4 receptor ligands in the treatment of il-6 involved diseases

Also Published As

Publication number Publication date
JP4889187B2 (en) 2012-03-07
WO2002036165A1 (en) 2002-05-10
US20060292147A1 (en) 2006-12-28
JPWO2002036165A1 (en) 2004-03-11

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