AU1870497A - Buffer systems for use in stabilizing pharmaceutical preparations - Google Patents

Buffer systems for use in stabilizing pharmaceutical preparations

Info

Publication number
AU1870497A
AU1870497A AU18704/97A AU1870497A AU1870497A AU 1870497 A AU1870497 A AU 1870497A AU 18704/97 A AU18704/97 A AU 18704/97A AU 1870497 A AU1870497 A AU 1870497A AU 1870497 A AU1870497 A AU 1870497A
Authority
AU
Australia
Prior art keywords
pharmaceutical preparations
buffer systems
stabilizing pharmaceutical
stabilizing
buffer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU18704/97A
Inventor
Detlef Goritz
Ralf-Siegbert Hauck
Georg Rossling
Andreas Sachse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU1870497A publication Critical patent/AU1870497A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/265—Citric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU18704/97A 1996-01-29 1996-12-20 Buffer systems for use in stabilizing pharmaceutical preparations Abandoned AU1870497A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19604230 1996-01-29
DE19604230 1996-01-29
PCT/DE1996/002488 WO1997028104A2 (en) 1996-01-29 1996-12-20 Buffer systems for use in stabilizing pharmaceutical preparations

Publications (1)

Publication Number Publication Date
AU1870497A true AU1870497A (en) 1997-08-22

Family

ID=7784639

Family Applications (1)

Application Number Title Priority Date Filing Date
AU18704/97A Abandoned AU1870497A (en) 1996-01-29 1996-12-20 Buffer systems for use in stabilizing pharmaceutical preparations

Country Status (7)

Country Link
EP (1) EP0877628A2 (en)
JP (1) JP2000504334A (en)
AU (1) AU1870497A (en)
CA (1) CA2244213A1 (en)
DE (1) DE19648650C2 (en)
NO (1) NO983464L (en)
WO (1) WO1997028104A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7250153B2 (en) * 2002-12-12 2007-07-31 Biophysica Research, Inc. Contrast media formulations having improved biological tolerance
JP2005170928A (en) * 2003-10-21 2005-06-30 Konica Minolta Medical & Graphic Inc Lyposome-containing x ray-imaging agent and method for producing the same
JP2005170923A (en) * 2003-10-21 2005-06-30 Konica Minolta Medical & Graphic Inc Lyposome-containing x ray-imaging agent and method for producing the same
JP2005220034A (en) * 2004-02-03 2005-08-18 Konica Minolta Medical & Graphic Inc Method for producing contrast medium for roentgenologic examination
JP4654590B2 (en) * 2004-03-31 2011-03-23 コニカミノルタエムジー株式会社 Contrast composition for X-ray CT and method for producing the same
US7588751B2 (en) * 2004-07-21 2009-09-15 Konica Minolta Medical & Graphic, Inc. Liposome-containing radiographic contrast medium and preparation method thereof
EP2550022B1 (en) * 2010-03-23 2020-12-09 GE Healthcare AS Preparation of stabilised x-ray diagnostic composition
US10383822B2 (en) 2012-08-10 2019-08-20 Taiho Pharmaceutical Co., Ltd. Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same
AU2014338864C1 (en) 2013-10-25 2020-07-16 Akamis Bio Limited Oncolytic adenoviruses armed with heterologous genes
MX2018007249A (en) 2015-12-17 2019-05-16 Psioxus Therapeutics Ltd Group b adenovirus encoding an anti-tcr-complex antibody or fragment.
JP6867639B2 (en) * 2016-10-11 2021-05-12 学校法人 聖マリアンナ医科大学 Combined nonionic iodine contrast agent
GB201801614D0 (en) * 2018-01-31 2018-03-14 Psioxus Therapeutics Ltd Formulation
EP4011369A1 (en) 2020-12-14 2022-06-15 G.L. Pharma GmbH Aqueous pharmaceutical composition comprising tapentadol tartrate
JP7353453B1 (en) 2022-10-31 2023-09-29 キユーピー株式会社 Emulsion and its manufacturing method
JP7372429B1 (en) 2022-10-31 2023-10-31 キユーピー株式会社 Emulsion and its manufacturing method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT371998B (en) * 1978-07-04 1983-08-25 Nyegaard & Co As METHOD FOR PRODUCING A STERILE INJECTABLE PHYSIOLOGICALLY ACCEPTABLE SOLUTION OF AN X-RAY CONTRAST AGENT
GB9020091D0 (en) * 1990-09-14 1990-10-24 Nycomed As Contrast media
DE4121568C2 (en) * 1991-04-22 1997-07-03 Schering Ag Method and device for producing a contrast medium from a concentrate
IT1256248B (en) * 1992-12-24 1995-11-29 Bracco Spa WATER INJECTABLE FORMULATIONS FOR RADIODIAGNOSTICS INCLUDING MIXTURES OF IODURATED AROMATIC COMPOUNDS USEFUL AS X-RAY MATTING AGENTS

Also Published As

Publication number Publication date
NO983464D0 (en) 1998-07-28
CA2244213A1 (en) 1997-08-07
DE19648650C2 (en) 1998-07-02
DE19648650A1 (en) 1997-08-07
WO1997028104A8 (en) 1997-12-18
EP0877628A2 (en) 1998-11-18
WO1997028104A2 (en) 1997-08-07
JP2000504334A (en) 2000-04-11
WO1997028104A3 (en) 1997-09-12
NO983464L (en) 1998-07-28

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