ATE278801T1 - Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor - Google Patents

Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor

Info

Publication number
ATE278801T1
ATE278801T1 AT96941438T AT96941438T ATE278801T1 AT E278801 T1 ATE278801 T1 AT E278801T1 AT 96941438 T AT96941438 T AT 96941438T AT 96941438 T AT96941438 T AT 96941438T AT E278801 T1 ATE278801 T1 AT E278801T1
Authority
AT
Austria
Prior art keywords
detection
optical sensor
biological molecules
chemical amplification
analyte
Prior art date
Application number
AT96941438T
Other languages
English (en)
Inventor
Antwerp William Peter Van
John Joseph Mastrototaro
Original Assignee
Medtronic Minimed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21726654&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE278801(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medtronic Minimed Inc filed Critical Medtronic Minimed Inc
Application granted granted Critical
Publication of ATE278801T1 publication Critical patent/ATE278801T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Optics & Photonics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT96941438T 1995-11-22 1996-11-21 Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor ATE278801T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US751595P 1995-11-22 1995-11-22
PCT/US1996/018720 WO1997019188A1 (en) 1995-11-22 1996-11-21 Detection of biological molecules using chemical amplification and optical sensors

Publications (1)

Publication Number Publication Date
ATE278801T1 true ATE278801T1 (de) 2004-10-15

Family

ID=21726654

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96941438T ATE278801T1 (de) 1995-11-22 1996-11-21 Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor

Country Status (8)

Country Link
US (3) US6011984A (de)
EP (1) EP0862648B1 (de)
JP (1) JP2000500656A (de)
AT (1) ATE278801T1 (de)
AU (1) AU1058297A (de)
CA (1) CA2235738C (de)
DE (1) DE69633573T2 (de)
WO (1) WO1997019188A1 (de)

Families Citing this family (577)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6002954A (en) * 1995-11-22 1999-12-14 The Regents Of The University Of California Detection of biological molecules using boronate-based chemical amplification and optical sensors
US6766183B2 (en) 1995-11-22 2004-07-20 Medtronic Minimed, Inc. Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers
US6011984A (en) * 1995-11-22 2000-01-04 Minimed Inc. Detection of biological molecules using chemical amplification and optical sensors
US6120460A (en) * 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
US6544193B2 (en) * 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
AU5446098A (en) * 1996-11-21 1998-06-10 Lawrence Livermore National Laboratory Detection of biological molecules using boronate-based chemical amplification and optical sensors
SE9700384D0 (sv) * 1997-02-04 1997-02-04 Biacore Ab Analytical method and apparatus
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US20050033132A1 (en) 1997-03-04 2005-02-10 Shults Mark C. Analyte measuring device
US6862465B2 (en) * 1997-03-04 2005-03-01 Dexcom, Inc. Device and method for determining analyte levels
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
US9155496B2 (en) 1997-03-04 2015-10-13 Dexcom, Inc. Low oxygen in vivo analyte sensor
US7657297B2 (en) 2004-05-03 2010-02-02 Dexcom, Inc. Implantable analyte sensor
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US7192450B2 (en) 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
TWI227323B (en) * 1998-03-11 2005-02-01 Sensors For Med & Science Inc Detection of analytes by fluorescent lanthanide metal chelate complexes containing substituted ligands
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) * 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8480580B2 (en) * 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) * 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
GB9814506D0 (en) * 1998-07-03 1998-09-02 Stanley Christopher J Optical sensor for insitu measurement of analytes
ES2275246T3 (es) * 1998-07-03 2007-06-01 Precisense A/S Sensor optico para la mencion de analitos in situ.
USRE38525E1 (en) 1998-07-03 2004-06-08 Torsana Diabetes Diagnostics A/S Optical sensor for in situ measurement of analytes
US6485703B1 (en) * 1998-07-31 2002-11-26 The Texas A&M University System Compositions and methods for analyte detection
US6558320B1 (en) * 2000-01-20 2003-05-06 Medtronic Minimed, Inc. Handheld personal data assistant (PDA) with a medical device and method of using the same
US6304766B1 (en) 1998-08-26 2001-10-16 Sensors For Medicine And Science Optical-based sensing devices, especially for in-situ sensing in humans
CN102226766B (zh) * 1998-08-26 2017-03-01 医药及科学传感器公司 基于光学的感测装置
US6350527B1 (en) * 1998-08-27 2002-02-26 Eidgenossische Technische Hochschule Zurich Gels and multilayer surface structures from boronic acid containing polymers
US6716969B1 (en) 1999-05-19 2004-04-06 North Carolina State University Reactive dye compounds
US6713613B1 (en) 1999-05-19 2004-03-30 North Carolina State University Reactive dye compounds
US6368274B1 (en) * 1999-07-01 2002-04-09 Medtronic Minimed, Inc. Reusable analyte sensor site and method of using the same
US7247138B2 (en) 1999-07-01 2007-07-24 Medtronic Minimed, Inc. Reusable analyte sensor site and method of using the same
DE60017755T2 (de) * 1999-08-26 2005-06-30 Novartis Ag Augenanalytfühler
US6366793B1 (en) * 1999-09-10 2002-04-02 Beckman Coulter, Inc. Minimally invasive methods for measuring analtes in vivo
US6682938B1 (en) 1999-09-15 2004-01-27 The Regents Of The University Of California Glucose sensing molecules having selected fluorescent properties
EP1214596A1 (de) * 1999-09-15 2002-06-19 The Regents Of The University Of California Für glukose sensitive moleküle mit ausgesuchten fluoreszenseigenschaften
US6673625B2 (en) 1999-09-15 2004-01-06 The Regents Of The University Of California Saccharide sensing molecules having enhanced fluorescent properties
US6869453B1 (en) 1999-10-01 2005-03-22 North Carolina State University Reactive dye compounds
GB9923332D0 (en) * 1999-10-01 1999-12-08 Procter & Gamble Reactive dye compounds
GB9923329D0 (en) * 1999-10-01 1999-12-08 Procter & Gamble Reactive dye compounds
US6790943B1 (en) 1999-10-01 2004-09-14 North Carolina State University Reactive dye compounds
US6723834B1 (en) 1999-10-01 2004-04-20 North Carolina State University Reactive dye compounds
US6736864B1 (en) 1999-10-01 2004-05-18 North Carolina State University Reactive dye compounds
US20030065308A1 (en) 2000-01-21 2003-04-03 Lebel Ronald J. Ambulatory medical apparatus with hand held communication device
DE10011284B4 (de) * 2000-03-08 2007-06-28 Disetronic Licensing Ag Vorrichtung für eine In-vivo Messung der Konzentration eines Inhaltsstoffs einer Körperflüssigkeit
WO2001075450A2 (en) * 2000-04-04 2001-10-11 The Regents Of The University Of California Fluorescent lifetime assays for non-invasive quantification of analytes
KR100922146B1 (ko) * 2000-08-04 2009-10-19 센서즈 포 메드슨 앤드 사이언스 인코포레이티드 수성 환경에서의 분석물 검출
GB0025147D0 (en) 2000-10-13 2000-11-29 Torsana Diabetes Diagnostics A Optical sensor for in situ measurement of analytes
US7470420B2 (en) 2000-12-05 2008-12-30 The Regents Of The University Of California Optical determination of glucose utilizing boronic acid adducts
US6653141B2 (en) * 2000-12-05 2003-11-25 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing method and device
US6627177B2 (en) * 2000-12-05 2003-09-30 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof
DE10063983A1 (de) * 2000-12-14 2002-07-04 Iom Innovative Optische Mestec Verfahren und Vorrichtung zum Nachweis von Zuckerkonzentrationen
US6560471B1 (en) * 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US20020119581A1 (en) * 2001-01-05 2002-08-29 Daniloff George Y. Detection of analytes
WO2002066986A2 (en) * 2001-02-15 2002-08-29 Medtronic Minimed, Inc. Polymers functionalized with fluorescent boronate motifs
US6952603B2 (en) * 2001-03-16 2005-10-04 Roche Diagnostics Operations, Inc. Subcutaneous analyte sensor
EP1392504A4 (de) * 2001-04-02 2008-03-05 Agilent Technologies Inc Sensorflächen zur erfassung von analyten
WO2002078512A2 (en) * 2001-04-02 2002-10-10 Therasense, Inc. Blood glucose tracking apparatus and methods
US7521019B2 (en) * 2001-04-11 2009-04-21 Lifescan, Inc. Sensor device and methods for manufacture
US6379622B1 (en) 2001-04-11 2002-04-30 Motorola, Inc. Sensor incorporating a quantum dot as a reference
US6694158B2 (en) 2001-04-11 2004-02-17 Motorola, Inc. System using a portable detection device for detection of an analyte through body tissue
US6454710B1 (en) 2001-04-11 2002-09-24 Motorola, Inc. Devices and methods for monitoring an analyte
EP1386140A1 (de) * 2001-05-04 2004-02-04 Sensors for Medicine and Science, Inc. Elektrooptischer sensor mit referenzkanal
GB0116853D0 (en) * 2001-07-10 2001-09-05 Torsana Diabetes Diagnostics A Optical sensor containing particles for in SITU measurement of analytes
US6702857B2 (en) * 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US8152789B2 (en) 2001-10-23 2012-04-10 Medtronic Minimed, Inc. System and method for providing closed loop infusion formulation delivery
US7045361B2 (en) 2001-09-12 2006-05-16 Medtronic Minimed, Inc. Analyte sensing via acridine-based boronate biosensors
US7096053B2 (en) 2001-10-02 2006-08-22 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Internal biochemical sensing device
US20050267326A1 (en) * 2001-10-02 2005-12-01 Alfred E. Mann Institute For Biomedical Eng. At The University Of Southern California Percutaneous chemical sensor based on fluorescence resonant energy transfer (FRET)
KR100437550B1 (ko) * 2001-10-09 2004-06-30 김환규 희토류 이온을 포함하는 착염형 사피린 덴드리머 화합물및 그 제조방법
KR100437549B1 (ko) * 2001-10-09 2004-06-30 김환규 에너지 전달 현상을 이용한 덴드리머형 폴피린 희토류이온 착화합물 및 그 제조방법
KR100437546B1 (ko) * 2001-10-09 2004-06-30 김환규 희토류 이온을 포함하는 착염형 폴피린 덴드리머 화합물및 그 제조방법
KR100437547B1 (ko) * 2001-10-09 2004-06-30 김환규 희토류 이온을 포함하는 착염형 텍사피린 덴드리머 화합물및 그 제조방법
US7192766B2 (en) 2001-10-23 2007-03-20 Medtronic Minimed, Inc. Sensor containing molded solidified protein
WO2003051191A1 (en) * 2001-12-17 2003-06-26 Danfoss A/S Method and device for monitoring analyte concentration by optical detection
US10080529B2 (en) 2001-12-27 2018-09-25 Medtronic Minimed, Inc. System for monitoring physiological characteristics
US7379765B2 (en) 2003-07-25 2008-05-27 Dexcom, Inc. Oxygen enhancing membrane systems for implantable devices
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US9282925B2 (en) * 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9247901B2 (en) 2003-08-22 2016-02-02 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7500949B2 (en) 2002-03-01 2009-03-10 Medtronic Minimed, Inc. Multilumen catheter
US20120078075A1 (en) * 2002-04-04 2012-03-29 Maynard John D Determination of a measure of a glycation end-product or disease state using tissue fluorescence in combination with one or more other tests
JP4347216B2 (ja) 2002-04-22 2009-10-21 マルシオ マルク アブリュー 生物学的パラメーターの測定装置
US8849379B2 (en) * 2002-04-22 2014-09-30 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
US8328420B2 (en) 2003-04-22 2012-12-11 Marcio Marc Abreu Apparatus and method for measuring biologic parameters
US10123732B2 (en) 2002-04-22 2018-11-13 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
AU2003249636A1 (en) * 2002-05-14 2003-11-11 North Carolina State University Fluorescent sensor compounds for detecting saccharides
US20060258761A1 (en) * 2002-05-22 2006-11-16 Robert Boock Silicone based membranes for use in implantable glucose sensors
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
US20040087842A1 (en) * 2002-05-30 2004-05-06 Lakowicz Joseph R. Fluorescent probes for saccharrides
US20040180379A1 (en) * 2002-08-30 2004-09-16 Northwestern University Surface-enhanced raman nanobiosensor
US20090118605A1 (en) * 2002-08-30 2009-05-07 Northwestern University Surface-enhanced raman nanobiosensor
ATE367449T1 (de) * 2002-09-20 2007-08-15 Univ Kingston Nachweis biologischer moleküle mittels differentieller aufteilung von enzymsubstraten und -produkten
US20070010726A1 (en) * 2002-10-02 2007-01-11 Alfred E. Mann Inst. For Biomedical Engineering At The University Of Southern California Internal biochemical sensing device
US7964390B2 (en) * 2002-10-11 2011-06-21 Case Western Reserve University Sensor system
US6623544B1 (en) 2002-10-31 2003-09-23 Kamaljit S. Kaura Air purification system and method of operation
AU2003287735A1 (en) * 2002-11-12 2004-06-03 Argose, Inc. Non-invasive measurement of analytes
US20040106163A1 (en) * 2002-11-12 2004-06-03 Workman Jerome James Non-invasive measurement of analytes
US20040115754A1 (en) * 2002-12-11 2004-06-17 Umax Data Systems Inc. Method for establishing a long-term profile of blood sugar level aiding self-control of the same
US7811231B2 (en) 2002-12-31 2010-10-12 Abbott Diabetes Care Inc. Continuous glucose monitoring system and methods of use
TW200411178A (en) * 2002-12-31 2004-07-01 Veutron Corp Method for determining the resolution of blood glucose by using rising time curve
US7390670B2 (en) * 2003-02-20 2008-06-24 Lumigen, Inc. Signalling compounds and methods for detecting hydrogen peroxide
TW592667B (en) * 2003-04-04 2004-06-21 Veutron Corp Method for determining the resolution of blood glucose
US7134999B2 (en) * 2003-04-04 2006-11-14 Dexcom, Inc. Optimized sensor geometry for an implantable glucose sensor
CA2820537C (en) 2003-04-23 2015-10-20 Valeritas, Inc. Hydraulically actuated pump for fluid administration
US20040234962A1 (en) * 2003-05-02 2004-11-25 Javier Alarcon Multicoated or multilayer entrapment matrix for protein biosensor
US7875293B2 (en) 2003-05-21 2011-01-25 Dexcom, Inc. Biointerface membranes incorporating bioactive agents
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
US20040259270A1 (en) * 2003-06-19 2004-12-23 Wolf David E. System, device and method for exciting a sensor and detecting analyte
WO2005010518A1 (en) * 2003-07-23 2005-02-03 Dexcom, Inc. Rolled electrode array and its method for manufacture
WO2005012871A2 (en) * 2003-07-25 2005-02-10 Dexcom, Inc. Increasing bias for oxygen production in an electrode system
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7460898B2 (en) * 2003-12-05 2008-12-02 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7761130B2 (en) * 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
JP2007500336A (ja) 2003-07-25 2007-01-11 デックスコム・インコーポレーテッド 電気化学センサーに用いる電極システム
US7467003B2 (en) * 2003-12-05 2008-12-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US20050176136A1 (en) * 2003-11-19 2005-08-11 Dexcom, Inc. Afinity domain for analyte sensor
US7366556B2 (en) 2003-12-05 2008-04-29 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7424318B2 (en) 2003-12-05 2008-09-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7651596B2 (en) 2005-04-08 2010-01-26 Dexcom, Inc. Cellulosic-based interference domain for an analyte sensor
WO2005017571A2 (en) * 2003-07-31 2005-02-24 Skymoon Research & Development Optical in vivo analyte probe using embedded intradermal particles
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US8845536B2 (en) * 2003-08-01 2014-09-30 Dexcom, Inc. Transcutaneous analyte sensor
US8761856B2 (en) 2003-08-01 2014-06-24 Dexcom, Inc. System and methods for processing analyte sensor data
US8060173B2 (en) * 2003-08-01 2011-11-15 Dexcom, Inc. System and methods for processing analyte sensor data
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US9135402B2 (en) 2007-12-17 2015-09-15 Dexcom, Inc. Systems and methods for processing sensor data
US7494465B2 (en) * 2004-07-13 2009-02-24 Dexcom, Inc. Transcutaneous analyte sensor
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US20100168543A1 (en) * 2003-08-01 2010-07-01 Dexcom, Inc. System and methods for processing analyte sensor data
US7519408B2 (en) * 2003-11-19 2009-04-14 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US20070066873A1 (en) * 2003-08-22 2007-03-22 Apurv Kamath Systems and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US20050090607A1 (en) * 2003-10-28 2005-04-28 Dexcom, Inc. Silicone composition for biocompatible membrane
US7190993B2 (en) * 2003-11-04 2007-03-13 Medtronic, Inc. Implantable medical device having optical fiber for sensing electrical activity
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US7368085B2 (en) * 2003-12-04 2008-05-06 Honeywell International Inc. Analyte detector
WO2005057168A2 (en) 2003-12-05 2005-06-23 Dexcom, Inc. Calibration techniques for a continuous analyte sensor
US8532730B2 (en) 2006-10-04 2013-09-10 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8287453B2 (en) 2003-12-05 2012-10-16 Dexcom, Inc. Analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
DE602004028164D1 (de) * 2003-12-08 2010-08-26 Dexcom Inc Systeme und verfahren zur verbesserung elektrochemischer analytsensoren
EP1711791B1 (de) * 2003-12-09 2014-10-15 DexCom, Inc. Signalverarbeitung für kontinuierlich arbeitenden analytsensor
US8029765B2 (en) * 2003-12-24 2011-10-04 Masimo Laboratories, Inc. SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors
US7637868B2 (en) * 2004-01-12 2009-12-29 Dexcom, Inc. Composite material for implantable device
US20050182451A1 (en) * 2004-01-12 2005-08-18 Adam Griffin Implantable device with improved radio frequency capabilities
US7427129B2 (en) * 2004-02-04 2008-09-23 Hewlett-Packard Development Company, L.P. Boronic acid containing dyes to improve permanence of images
US7364592B2 (en) * 2004-02-12 2008-04-29 Dexcom, Inc. Biointerface membrane with macro-and micro-architecture
WO2005089103A2 (en) 2004-02-17 2005-09-29 Therasense, Inc. Method and system for providing data communication in continuous glucose monitoring and management system
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
WO2009048462A1 (en) 2007-10-09 2009-04-16 Dexcom, Inc. Integrated insulin delivery system with continuous glucose sensor
US10227063B2 (en) 2004-02-26 2019-03-12 Geelux Holdings, Ltd. Method and apparatus for biological evaluation
US7713745B2 (en) 2004-04-13 2010-05-11 Sensors For Medicine And Science, Inc. Non-covalent immobilization of indicator molecules
US8792955B2 (en) 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
US20050245799A1 (en) * 2004-05-03 2005-11-03 Dexcom, Inc. Implantable analyte sensor
US8277713B2 (en) * 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
CA2565624A1 (en) * 2004-05-04 2005-11-17 University Of Rochester Implantable bio-electro-physiologic interface matrix
EP1753506A4 (de) * 2004-05-04 2008-06-11 Univ Rochester Leitungsloser implantierbarer kardioverter-defribrillator
US8938300B2 (en) * 2004-05-04 2015-01-20 University Of Rochester Leadless implantable intravascular electrophysiologic device for neurologic/cardiovascular sensing and stimulation
GB0411162D0 (en) 2004-05-19 2004-06-23 Precisense As Optical sensor for in vivo detection of analyte
WO2006009910A2 (en) * 2004-06-17 2006-01-26 The Regents Of The University Of California Time-resolved optometric fluorescence detection for skin diagnostics
WO2006009906A2 (en) * 2004-06-17 2006-01-26 The Regents Of The University Of California Time-resolved non-invasive autofluorescence device for detecting diabetes
US9089636B2 (en) * 2004-07-02 2015-07-28 Valeritas, Inc. Methods and devices for delivering GLP-1 and uses thereof
US7640048B2 (en) * 2004-07-13 2009-12-29 Dexcom, Inc. Analyte sensor
US7783333B2 (en) 2004-07-13 2010-08-24 Dexcom, Inc. Transcutaneous medical device with variable stiffness
US20070045902A1 (en) * 2004-07-13 2007-03-01 Brauker James H Analyte sensor
US8565848B2 (en) * 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US20060020192A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
EP1619229B1 (de) * 2004-07-23 2007-04-11 Terumo Kabushiki Kaisha Saccharid-messender fluoreszierender Monomer, Saccharid-messende fluoreszierende Sensor-Substanz und implantierbarer, Saccharid-messender Sensor
US7867160B2 (en) * 2004-10-12 2011-01-11 Earlens Corporation Systems and methods for photo-mechanical hearing transduction
CN101091114A (zh) * 2004-08-31 2007-12-19 生命扫描苏格兰有限公司 制造自动校准传感器的方法
DE102004044717B8 (de) * 2004-09-10 2010-12-16 BAM Bundesanstalt für Materialforschung und -prüfung Verfahren und Kit zur Kalibrierung eines Photolumineszenzmesssystems
JP4558448B2 (ja) * 2004-11-01 2010-10-06 テルモ株式会社 光導波路およびこの光導波路を用いた蛍光センサ
GB0426823D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
GB0426822D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
AU2006223384B2 (en) * 2005-03-09 2012-08-02 Cepheid Polar dyes
US20090076360A1 (en) * 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
US20060229507A1 (en) * 2005-03-30 2006-10-12 Kermani Mahyar Z Adhesive fluorescence measurement band
US20060224056A1 (en) * 2005-03-30 2006-10-05 Kermani Mahyar Z Method for monitoring an implanted fluorescent light-emitting bead
US20060229508A1 (en) * 2005-03-30 2006-10-12 Kermani Mahyar Z Adhesive fluorescence measurement patch
US20060224055A1 (en) * 2005-03-30 2006-10-05 Kermani Mahyar Z Fluorescence measurement analytical kit
US8744546B2 (en) * 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
US7308292B2 (en) 2005-04-15 2007-12-11 Sensors For Medicine And Science, Inc. Optical-based sensing devices
US8060174B2 (en) 2005-04-15 2011-11-15 Dexcom, Inc. Analyte sensing biointerface
US8112240B2 (en) * 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
WO2006121661A2 (en) * 2005-05-05 2006-11-16 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
US7629174B2 (en) * 2005-08-26 2009-12-08 Honeywell International Inc. Analyte detector
SG180045A1 (en) 2005-10-24 2012-05-30 Marcio Marc Abreu Apparatus and method for measuring biologic parameters
US20090054747A1 (en) * 2005-10-31 2009-02-26 Abbott Diabetes Care, Inc. Method and system for providing analyte sensor tester isolation
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US9757061B2 (en) 2006-01-17 2017-09-12 Dexcom, Inc. Low oxygen in vivo analyte sensor
EP2004796B1 (de) * 2006-01-18 2015-04-08 DexCom, Inc. Membranen für einen analytsensor
ES2566058T3 (es) 2006-03-30 2016-04-08 Valeritas, Inc. Dispositivo de suministro de fluidos de múltiples cartuchos
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
WO2007120381A2 (en) 2006-04-14 2007-10-25 Dexcom, Inc. Analyte sensor
WO2007134177A2 (en) * 2006-05-11 2007-11-22 President And Fellows Of Harvard College Methods, materials and devices for light manipulation with oriented molecular assemblies in micronscale photonic circuit elements with high-q or slow light
US7809441B2 (en) * 2006-05-17 2010-10-05 Cardiac Pacemakers, Inc. Implantable medical device with chemical sensor and related methods
US20090054749A1 (en) * 2006-05-31 2009-02-26 Abbott Diabetes Care, Inc. Method and System for Providing Data Transmission in a Data Management System
WO2007143225A2 (en) * 2006-06-07 2007-12-13 Abbott Diabetes Care, Inc. Analyte monitoring system and method
US20070298487A1 (en) * 2006-06-23 2007-12-27 Becton, Dickinson And Company Radio Frequency Transponder Assay
US8326390B2 (en) * 2006-07-25 2012-12-04 Edward Belotserkovsky Optical non-invasive blood monitoring system and method
US7486976B1 (en) 2006-07-25 2009-02-03 Edward Belotserkovsky Optical non-invasive blood monitoring system and method
ATE514755T1 (de) * 2006-07-25 2011-07-15 Glumetrics Inc Fluoreszenzfarbstoffe zur verwendung bei der glukoseerfassung
ATE416526T1 (de) * 2006-08-25 2008-12-15 Alcatel Lucent Digitalsignalempfänger mit q-faktorüberwachung
KR100770440B1 (ko) * 2006-08-29 2007-10-26 삼성전기주식회사 질화물 반도체 발광소자
US9056165B2 (en) 2006-09-06 2015-06-16 Medtronic Minimed, Inc. Intelligent therapy recommendation algorithm and method of using the same
US8400639B2 (en) * 2006-09-15 2013-03-19 President And Fellows Of Harvard College Methods and devices for measurements using pump-probe spectroscopy in high-Q microcavities
US7831287B2 (en) * 2006-10-04 2010-11-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US10914698B2 (en) 2006-11-16 2021-02-09 General Electric Company Sensing method and system
US9658178B2 (en) 2012-09-28 2017-05-23 General Electric Company Sensor systems for measuring an interface level in a multi-phase fluid composition
US9589686B2 (en) 2006-11-16 2017-03-07 General Electric Company Apparatus for detecting contaminants in a liquid and a system for use thereof
US9538657B2 (en) 2012-06-29 2017-01-03 General Electric Company Resonant sensor and an associated sensing method
US20100134286A1 (en) * 2008-12-01 2010-06-03 General Electric Company Radio frequency based sensors employing analyte recognition element
US9536122B2 (en) 2014-11-04 2017-01-03 General Electric Company Disposable multivariable sensing devices having radio frequency based sensors
SG179448A1 (en) * 2006-11-30 2012-04-27 Sensors For Med & Science Inc Oxidation resistant indicator molecules
WO2008143651A2 (en) * 2006-12-07 2008-11-27 The Ohio State University Research Foundation A system for in vivo biosensing based on the optical response of electronic polymers
US7946985B2 (en) 2006-12-29 2011-05-24 Medtronic Minimed, Inc. Method and system for providing sensor redundancy
US20080214912A1 (en) * 2007-01-10 2008-09-04 Glucose Sensing Technologies, Llc Blood Glucose Monitoring System And Method
US10154804B2 (en) 2007-01-31 2018-12-18 Medtronic Minimed, Inc. Model predictive method and system for controlling and supervising insulin infusion
JP2010517693A (ja) * 2007-02-06 2010-05-27 グルメトリクス， インコーポレイテッド 血中グルコース濃度のレシオメトリック測定のための光学系及び方法
US7751863B2 (en) 2007-02-06 2010-07-06 Glumetrics, Inc. Optical determination of ph and glucose
US8088097B2 (en) * 2007-11-21 2012-01-03 Glumetrics, Inc. Use of an equilibrium intravascular sensor to achieve tight glycemic control
US8396539B2 (en) 2007-02-16 2013-03-12 Medtronic, Inc. Implantable medical device having optical fiber for sensing electrical activity
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8732188B2 (en) * 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US20080281179A1 (en) * 2007-05-08 2008-11-13 Abbott Diabetes Care, Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8461985B2 (en) * 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
EP2162057A1 (de) * 2007-05-10 2010-03-17 Glumetrics, Inc. Verschleissbeständiger gleichgewichtsfluoreszenzsensor für intravaskuläre echtzeit-glukosemessung
JP2010527010A (ja) * 2007-05-10 2010-08-05 グルメトリクス、 インク． 被分析物センサーを較正する装置および方法
US20200037875A1 (en) 2007-05-18 2020-02-06 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
DE102007024642A1 (de) * 2007-05-24 2008-11-27 Eyesense Ag Hydrogel-Implantat für Sensorik von Metaboliten am Auge
US20080306434A1 (en) 2007-06-08 2008-12-11 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US20090014340A1 (en) * 2007-06-15 2009-01-15 Williams John R Devices, systems, and methods for measuring glucose
WO2009009756A2 (en) 2007-07-11 2009-01-15 Glumetrics, Inc. Polyviologen boronic acid quenchers for use in analyte sensors
EP3078714A1 (de) 2007-08-06 2016-10-12 Medtronic Minimed, Inc. Polymerisierbare, fluoreszente hpts-mono- und -bis-cys-ma-farbstoffe zur verwendung in analytsensoren
US9968742B2 (en) 2007-08-29 2018-05-15 Medtronic Minimed, Inc. Combined sensor and infusion set using separated sites
US20120046533A1 (en) 2007-08-29 2012-02-23 Medtronic Minimed, Inc. Combined sensor and infusion sets
EP2208367B1 (de) 2007-10-12 2017-09-27 Earlens Corporation Multifunktionssystem und verfahren zum integrierten hören und kommunizieren mit geräuschlöschung und rückkopplungsverwaltung
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
US8417312B2 (en) 2007-10-25 2013-04-09 Dexcom, Inc. Systems and methods for processing sensor data
US8290559B2 (en) 2007-12-17 2012-10-16 Dexcom, Inc. Systems and methods for processing sensor data
CA2715628A1 (en) * 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US8396528B2 (en) 2008-03-25 2013-03-12 Dexcom, Inc. Analyte sensor
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
WO2009129186A2 (en) * 2008-04-17 2009-10-22 Glumetrics, Inc. Sensor for percutaneous intravascular deployment without an indwelling cannula
TWI394580B (zh) 2008-04-28 2013-05-01 Halozyme Inc 超快起作用胰島素組成物
BRPI0915203A2 (pt) 2008-06-17 2016-02-16 Earlens Corp dispostivo, sistema e método para transmitir um sinal de áudio, e, dispostivo e método para estimular um tecido alvo
WO2009155450A2 (en) 2008-06-20 2009-12-23 Board Of Regents, The University Of Texas System Biodegradable photoluminescent polymers
US8181531B2 (en) * 2008-06-27 2012-05-22 Edwin Carlen Accessible stress-based electrostatic monitoring of chemical reactions and binding
KR100971157B1 (ko) * 2008-07-29 2010-07-20 경북대학교 산학협력단 나노섬유막을 포함하는 포도당 감지 조성물 및 이를 이용한무효소 포도당 바이오 센서 제조방법
US8700114B2 (en) 2008-07-31 2014-04-15 Medtronic Minmed, Inc. Analyte sensor apparatuses comprising multiple implantable sensor elements and methods for making and using them
US9011670B2 (en) * 2008-08-14 2015-04-21 The Charles Stark Draper Laboratory, Inc. Three-dimensional metal ion sensor arrays on printed circuit boards
EP3795987B1 (de) 2008-09-19 2023-10-25 Dexcom, Inc. Partikelhaltige membran und partikelelektrode für analytsensoren
BRPI0918994A2 (pt) 2008-09-22 2017-06-13 SoundBeam LLC dispositivo, e, método para transmitir um sinal de áudio para um usuário.
EP2378954A4 (de) * 2008-12-24 2013-05-15 Glusense Ltd Implantierbare optische glusosemessung
US8103456B2 (en) * 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US9226701B2 (en) * 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
US9184490B2 (en) 2009-05-29 2015-11-10 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
US9517023B2 (en) 2009-06-01 2016-12-13 Profusa, Inc. Method and system for directing a localized biological response to an implant
AT507659B1 (de) * 2009-06-09 2010-07-15 Joanneum Res Forschungsgmbh Vorrichtung zur transkutanen, in-vivo messung der konzentration zumindest eines analyten in einem lebenden organismus
US8993331B2 (en) 2009-08-31 2015-03-31 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
WO2011026147A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte signal processing device and methods
WO2011041469A1 (en) * 2009-09-29 2011-04-07 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
EP2483679A4 (de) 2009-09-30 2013-04-24 Glumetrics Inc Sensoren mit thrombenresistenter beschichtung
US20110082356A1 (en) 2009-10-01 2011-04-07 Medtronic Minimed, Inc. Analyte sensor apparatuses having interference rejection membranes and methods for making and using them
US8467843B2 (en) 2009-11-04 2013-06-18 Glumetrics, Inc. Optical sensor configuration for ratiometric correction of blood glucose measurement
US20110288388A1 (en) 2009-11-20 2011-11-24 Medtronic Minimed, Inc. Multi-conductor lead configurations useful with medical device systems and methods for making and using them
WO2011075710A1 (en) * 2009-12-17 2011-06-23 Glumetrics, Inc. Identification of aberrant measurements of in vivo glucose concentration using temperature
US8660628B2 (en) 2009-12-21 2014-02-25 Medtronic Minimed, Inc. Analyte sensors comprising blended membrane compositions and methods for making and using them
US8070723B2 (en) 2009-12-31 2011-12-06 Medtronic Minimed, Inc. Activity guard
WO2011097586A1 (en) 2010-02-08 2011-08-11 Glumetrics, Inc. Antioxidant protection of a chemical sensor
EP2545373B1 (de) * 2010-03-11 2022-08-24 Medtronic Minimed, Inc. Messung von analytkonzentrationen einschliesslich temperatur- und ph-korrektur
US10448872B2 (en) 2010-03-16 2019-10-22 Medtronic Minimed, Inc. Analyte sensor apparatuses having improved electrode configurations and methods for making and using them
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
US9215995B2 (en) 2010-06-23 2015-12-22 Medtronic Minimed, Inc. Sensor systems having multiple probes and electrode arrays
WO2012043177A1 (ja) 2010-09-30 2012-04-05 テルモ株式会社 蛍光ハイドロゲルおよびその製造方法、ならびにそれを用いた糖類測定用センサー
CN105147300B (zh) * 2010-10-06 2019-09-03 普罗弗萨股份有限公司 组织整合性传感器
US8542023B2 (en) 2010-11-09 2013-09-24 General Electric Company Highly selective chemical and biological sensors
DK2656639T3 (da) 2010-12-20 2020-06-29 Earlens Corp Anatomisk tilpasset øregangshøreapparat
US8628510B2 (en) 2010-12-22 2014-01-14 Medtronic Minimed, Inc. Monitoring the operating health of a force sensor in a fluid infusion device
US8532775B2 (en) 2011-02-18 2013-09-10 Medtronic, Inc. Modular medical device programmer
CN103370099B (zh) 2011-02-18 2016-01-13 美敦力公司 具有可调节支架的医疗装置编程器
US9339639B2 (en) 2011-02-22 2016-05-17 Medtronic Minimed, Inc. Sealing assembly for a fluid reservoir of a fluid infusion device
US11266823B2 (en) 2011-02-22 2022-03-08 Medtronic Minimed, Inc. Retractable sealing assembly for a fluid reservoir of a fluid infusion device
EP3575796B1 (de) 2011-04-15 2020-11-11 DexCom, Inc. Erweiterte analytsensorkalibrierung und fehlererkennung
US9008744B2 (en) 2011-05-06 2015-04-14 Medtronic Minimed, Inc. Method and apparatus for continuous analyte monitoring
US8795231B2 (en) 2011-05-10 2014-08-05 Medtronic Minimed, Inc. Automated reservoir fill system
GB201113435D0 (en) 2011-08-03 2011-09-21 Glysure Ltd Sensor calibration
US9993529B2 (en) 2011-06-17 2018-06-12 Halozyme, Inc. Stable formulations of a hyaluronan-degrading enzyme
BR112013032265A2 (pt) 2011-06-17 2016-12-20 Halozyme Inc métodos de infusão de insulina subcutânea contínua com uma enzima de degradação do hialuronano
WO2013012687A2 (en) 2011-07-15 2013-01-24 Glumetrics, Inc. Combinations of fluorphores and pyridinium boronic acid quenchers for use in analyte sensors
WO2013049068A1 (en) 2011-09-27 2013-04-04 Glumetrics, Inc. Method for functionalizing a porous membrane covering of an optical sensor to facilitate coupling of an antithrom-bogenic agent
US9989522B2 (en) 2011-11-01 2018-06-05 Medtronic Minimed, Inc. Methods and materials for modulating start-up time and air removal in dry sensors
JP6443802B2 (ja) 2011-11-07 2018-12-26 アボット ダイアベティス ケア インコーポレイテッドＡｂｂｏｔｔ Ｄｉａｂｅｔｅｓ Ｃａｒｅ Ｉｎｃ． 分析物モニタリング装置および方法
US8999720B2 (en) 2011-11-17 2015-04-07 Medtronic Minimed, Inc. Aqueous radiation protecting formulations and methods for making and using them
US9176032B2 (en) 2011-12-23 2015-11-03 General Electric Company Methods of analyzing an H and E stained biological sample
US8568991B2 (en) 2011-12-23 2013-10-29 General Electric Company Photoactivated chemical bleaching of dyes
US9610401B2 (en) 2012-01-13 2017-04-04 Medtronic Minimed, Inc. Infusion set component with modular fluid channel element
US9017622B2 (en) 2012-04-10 2015-04-28 Lightship Medical Limited Calibrator for a sensor
US9493807B2 (en) 2012-05-25 2016-11-15 Medtronic Minimed, Inc. Foldover sensors and methods for making and using them
US9357958B2 (en) 2012-06-08 2016-06-07 Medtronic Minimed, Inc. Application of electrochemical impedance spectroscopy in sensor systems, devices, and related methods
US20130344619A1 (en) 2012-06-21 2013-12-26 Lightship Medical Limited Glucose sensor
JP6321004B2 (ja) 2012-07-10 2018-05-09 ザ ジェネラル ホスピタル コーポレイション 対象のモニタリングと表面処理のためのシステムおよび方法
US9682188B2 (en) 2012-08-21 2017-06-20 Medtronic Minimed, Inc. Reservoir fluid volume estimator and medical device incorporating same
JP6251270B2 (ja) 2012-08-22 2017-12-20 ゼネラル・エレクトリック・カンパニイ 機械の動作状態を測定するためのワイヤレスシステムおよび方法
US10598650B2 (en) 2012-08-22 2020-03-24 General Electric Company System and method for measuring an operative condition of a machine
US10496797B2 (en) 2012-08-30 2019-12-03 Medtronic Minimed, Inc. Blood glucose validation for a closed-loop operating mode of an insulin infusion system
US9623179B2 (en) 2012-08-30 2017-04-18 Medtronic Minimed, Inc. Safeguarding techniques for a closed-loop insulin infusion system
US10130767B2 (en) 2012-08-30 2018-11-20 Medtronic Minimed, Inc. Sensor model supervisor for a closed-loop insulin infusion system
US9878096B2 (en) 2012-08-30 2018-01-30 Medtronic Minimed, Inc. Generation of target glucose values for a closed-loop operating mode of an insulin infusion system
US9849239B2 (en) 2012-08-30 2017-12-26 Medtronic Minimed, Inc. Generation and application of an insulin limit for a closed-loop operating mode of an insulin infusion system
US9662445B2 (en) 2012-08-30 2017-05-30 Medtronic Minimed, Inc. Regulating entry into a closed-loop operating mode of an insulin infusion system
KR102147850B1 (ko) 2012-08-30 2020-08-26 메드트로닉 미니메드 인코포레이티드 폐쇄-루프 인슐린 주입 시스템을 위한 보호 기술
US20140066884A1 (en) 2012-08-30 2014-03-06 Medtronic Minimed, Inc. Sensor model supervisor for a closed-loop insulin infusion system
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
US10684268B2 (en) 2012-09-28 2020-06-16 Bl Technologies, Inc. Sensor systems for measuring an interface level in a multi-phase fluid composition
WO2014074621A1 (en) 2012-11-07 2014-05-15 Glumetrics, Inc. Dry insertion and one-point in vivo calibration of an optical analyte sensor
US9265455B2 (en) 2012-11-13 2016-02-23 Medtronic Minimed, Inc. Methods and systems for optimizing sensor function by the application of voltage
US10194840B2 (en) 2012-12-06 2019-02-05 Medtronic Minimed, Inc. Microarray electrodes useful with analyte sensors and methods for making and using them
US10426383B2 (en) 2013-01-22 2019-10-01 Medtronic Minimed, Inc. Muting glucose sensor oxygen response and reducing electrode edge growth with pulsed current plating
US9915592B2 (en) 2013-03-06 2018-03-13 General Electric Company Methods of analyzing an H and E stained biological sample
CN105120750B (zh) * 2013-03-14 2018-01-12 普罗菲尤萨股份有限公司 用于校正光学信号的方法和装置
US20140350370A1 (en) * 2013-04-08 2014-11-27 The Texas A&M University System Glucose sensing assay
US9338819B2 (en) 2013-05-29 2016-05-10 Medtronic Minimed, Inc. Variable data usage personal medical system and method
EP3777656A1 (de) * 2013-06-06 2021-02-17 Profusa, Inc. Vorrichtung und verfahren zur detektion optischer signale aus implantierten sensoren
US10194864B2 (en) 2013-06-21 2019-02-05 Medtronic Minimed, Inc. Anchoring apparatus and method for attaching device on body
US9789206B2 (en) 2013-07-10 2017-10-17 The General Hospital Corporation Compounds, systems, and methods for monitoring and treating a surface of a subject
US9880528B2 (en) 2013-08-21 2018-01-30 Medtronic Minimed, Inc. Medical devices and related updating methods and systems
AU2014331655A1 (en) 2013-10-11 2016-05-26 Marcio Marc Abreu Method and apparatus for biological evaluation
US8979808B1 (en) 2013-10-14 2015-03-17 Medtronic Minimed, Inc. On-body injector and method of use
US9265881B2 (en) 2013-10-14 2016-02-23 Medtronic Minimed, Inc. Therapeutic agent injection device
US8979799B1 (en) 2013-10-14 2015-03-17 Medtronic Minimed, Inc. Electronic injector
US9375537B2 (en) 2013-10-14 2016-06-28 Medtronic Minimed, Inc. Therapeutic agent injection device
US9936905B2 (en) 2013-10-25 2018-04-10 Medtronic Minimed, Inc. Sensor with optical interface
US9226709B2 (en) 2013-11-04 2016-01-05 Medtronic Minimed, Inc. ICE message system and method
US9267875B2 (en) 2013-11-21 2016-02-23 Medtronic Minimed, Inc. Accelerated life testing device and method
US9750877B2 (en) 2013-12-11 2017-09-05 Medtronic Minimed, Inc. Predicted time to assess and/or control a glycemic state
US9849240B2 (en) 2013-12-12 2017-12-26 Medtronic Minimed, Inc. Data modification for predictive operations and devices incorporating same
US10105488B2 (en) 2013-12-12 2018-10-23 Medtronic Minimed, Inc. Predictive infusion device operations and related methods and systems
US10945630B2 (en) 2013-12-16 2021-03-16 Medtronic Minimed, Inc. Use of Electrochemical Impedance Spectroscopy (EIS) in gross failure analysis
US9649058B2 (en) 2013-12-16 2017-05-16 Medtronic Minimed, Inc. Methods and systems for improving the reliability of orthogonally redundant sensors
US9779226B2 (en) 2013-12-18 2017-10-03 Medtronic Minimed, Inc. Fingerprint enhanced authentication for medical devices in wireless networks
US9143941B2 (en) 2013-12-18 2015-09-22 Medtronic Minimed, Inc. Secure communication by user selectable communication range
US9694132B2 (en) 2013-12-19 2017-07-04 Medtronic Minimed, Inc. Insertion device for insertion set
JP2017505657A (ja) 2014-01-10 2017-02-23 マーシオ マーク アブリュー Ａｂｒｅｕ脳トンネルでモニタして治療を提供するデバイス
AU2015204638A1 (en) 2014-01-10 2016-07-21 Marcio Marc Abreu Device for measuring the infrared output of the Abreu brain thermal tunnel
WO2015112776A2 (en) 2014-01-22 2015-07-30 Marcio Marc Abreu Devices configured to provide treatment at an abreu brain thermal tunnel
US9898585B2 (en) 2014-01-31 2018-02-20 Aseko, Inc. Method and system for insulin management
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US9861748B2 (en) 2014-02-06 2018-01-09 Medtronic Minimed, Inc. User-configurable closed-loop notifications and infusion systems incorporating same
US10034103B2 (en) 2014-03-18 2018-07-24 Earlens Corporation High fidelity and reduced feedback contact hearing apparatus and methods
US9388805B2 (en) 2014-03-24 2016-07-12 Medtronic Minimed, Inc. Medication pump test device and method of use
US9689830B2 (en) 2014-04-03 2017-06-27 Medtronic Minimed, Inc. Sensor detection pads with integrated fuse
US9707336B2 (en) 2014-04-07 2017-07-18 Medtronic Minimed, Inc. Priming detection system and method of using the same
US10232113B2 (en) 2014-04-24 2019-03-19 Medtronic Minimed, Inc. Infusion devices and related methods and systems for regulating insulin on board
US9681828B2 (en) 2014-05-01 2017-06-20 Medtronic Minimed, Inc. Physiological characteristic sensors and methods for forming such sensors
US9901305B2 (en) 2014-06-13 2018-02-27 Medtronic Minimed, Inc. Physiological sensor history backfill system and method
EP3169396B1 (de) 2014-07-14 2021-04-21 Earlens Corporation Gleitende vorspannung und spitzenunterdrückung für optische hörgeräte
US10821222B2 (en) 2014-07-21 2020-11-03 Medtronic Minimed, Inc. Smart connection interface
US9717845B2 (en) 2014-08-19 2017-08-01 Medtronic Minimed, Inc. Geofencing for medical devices
US20160051755A1 (en) 2014-08-25 2016-02-25 Medtronic Minimed, Inc. Low cost fluid delivery device
US9839753B2 (en) 2014-09-26 2017-12-12 Medtronic Minimed, Inc. Systems for managing reservoir chamber pressure
US10279126B2 (en) 2014-10-07 2019-05-07 Medtronic Minimed, Inc. Fluid conduit assembly with gas trapping filter in the fluid flow path
US10575765B2 (en) 2014-10-13 2020-03-03 Glusense Ltd. Analyte-sensing device
US9592335B2 (en) 2014-10-20 2017-03-14 Medtronic Minimed, Inc. Insulin pump data acquisition device
US9841014B2 (en) 2014-10-20 2017-12-12 Medtronic Minimed, Inc. Insulin pump data acquisition device and system
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
WO2016069475A1 (en) 2014-10-27 2016-05-06 Aseko, Inc. Subcutaneous outpatient management
US9731067B2 (en) 2014-11-25 2017-08-15 Medtronic Minimed, Inc. Mechanical injection pump and method of use
US9901675B2 (en) 2014-11-25 2018-02-27 Medtronic Minimed, Inc. Infusion set insertion device and method of use
US9924276B2 (en) 2014-11-26 2018-03-20 Earlens Corporation Adjustable venting for hearing instruments
US9636453B2 (en) 2014-12-04 2017-05-02 Medtronic Minimed, Inc. Advance diagnosis of infusion device operating mode viability
US9943645B2 (en) 2014-12-04 2018-04-17 Medtronic Minimed, Inc. Methods for operating mode transitions and related infusion devices and systems
US10307535B2 (en) 2014-12-19 2019-06-04 Medtronic Minimed, Inc. Infusion devices and related methods and systems for preemptive alerting
US9717848B2 (en) 2015-01-22 2017-08-01 Medtronic Minimed, Inc. Data derived pre-bolus delivery
US9872954B2 (en) 2015-03-02 2018-01-23 Medtronic Minimed, Inc. Belt clip
US10307528B2 (en) 2015-03-09 2019-06-04 Medtronic Minimed, Inc. Extensible infusion devices and related methods
EP3267877A1 (de) 2015-03-10 2018-01-17 Marcio Marc Abreu Vorrichtungen, einrichtungen, systeme und verfahren zur messung der temperatur eines abtt-terminus
US10449298B2 (en) 2015-03-26 2019-10-22 Medtronic Minimed, Inc. Fluid injection devices and related methods
US10130757B2 (en) 2015-05-01 2018-11-20 Medtronic Minimed, Inc. Method and system for leakage detection in portable medical devices
US9999721B2 (en) 2015-05-26 2018-06-19 Medtronic Minimed, Inc. Error handling in infusion devices with distributed motor control and related operating methods
US20160354500A1 (en) 2015-06-02 2016-12-08 Medtronic Minimed, Inc. Protective agents against e-beam irradiation for proteins in optical sensing chemistry
US10716500B2 (en) 2015-06-29 2020-07-21 Cardiac Pacemakers, Inc. Systems and methods for normalization of chemical sensor data based on fluid state changes
US9886556B2 (en) 2015-08-20 2018-02-06 Aseko, Inc. Diabetes management therapy advisor
US10293108B2 (en) 2015-08-21 2019-05-21 Medtronic Minimed, Inc. Infusion devices and related patient ratio adjustment methods
US10201657B2 (en) 2015-08-21 2019-02-12 Medtronic Minimed, Inc. Methods for providing sensor site rotation feedback and related infusion devices and systems
US10543314B2 (en) 2015-08-21 2020-01-28 Medtronic Minimed, Inc. Personalized parameter modeling with signal calibration based on historical data
US10117992B2 (en) 2015-09-29 2018-11-06 Medtronic Minimed, Inc. Infusion devices and related rescue detection methods
EP3888564A1 (de) 2015-10-02 2021-10-06 Earlens Corporation Angepasste gehörgangvorrichtung zur arzneimittelabgabe
US9992818B2 (en) 2015-10-06 2018-06-05 Medtronic Minimed, Inc. Protocol translation device
US9757511B2 (en) 2015-10-19 2017-09-12 Medtronic Minimed, Inc. Personal medical device and method of use with restricted mode challenge
US11666702B2 (en) 2015-10-19 2023-06-06 Medtronic Minimed, Inc. Medical devices and related event pattern treatment recommendation methods
US11501867B2 (en) 2015-10-19 2022-11-15 Medtronic Minimed, Inc. Medical devices and related event pattern presentation methods
US10146911B2 (en) 2015-10-23 2018-12-04 Medtronic Minimed, Inc. Medical devices and related methods and systems for data transfer
US10037722B2 (en) 2015-11-03 2018-07-31 Medtronic Minimed, Inc. Detecting breakage in a display element
US10827959B2 (en) 2015-11-11 2020-11-10 Medtronic Minimed, Inc. Sensor set
US9848805B2 (en) 2015-12-18 2017-12-26 Medtronic Minimed, Inc. Biostable glucose permeable polymer
US10327680B2 (en) 2015-12-28 2019-06-25 Medtronic Minimed, Inc. Sensor systems, devices, and methods for continuous glucose monitoring
US10349872B2 (en) 2015-12-28 2019-07-16 Medtronic Minimed, Inc. Methods, systems, and devices for sensor fusion
US20170181672A1 (en) 2015-12-28 2017-06-29 Medtronic Minimed, Inc. Sensor systems, devices, and methods for continuous glucose monitoring
US10327686B2 (en) 2015-12-28 2019-06-25 Medtronic Minimed, Inc. Sensor systems, devices, and methods for continuous glucose monitoring
US11350226B2 (en) 2015-12-30 2022-05-31 Earlens Corporation Charging protocol for rechargeable hearing systems
WO2017116791A1 (en) 2015-12-30 2017-07-06 Earlens Corporation Light based hearing systems, apparatus and methods
US10492010B2 (en) 2015-12-30 2019-11-26 Earlens Corporations Damping in contact hearing systems
US10790054B1 (en) 2016-12-07 2020-09-29 Medtronic Minimed, Inc. Method and apparatus for tracking of food intake and other behaviors and providing relevant feedback
WO2017132690A1 (en) 2016-01-28 2017-08-03 Savor Labs, Inc. Method and apparatus for tracking of food intake and other behaviors and providing relevant feedback
US20170290535A1 (en) 2016-04-08 2017-10-12 Medtronic Minimed, Inc. Analyte sensor with indicators
US10413183B2 (en) 2016-04-08 2019-09-17 Medtronic Minimed, Inc. Insertion device
US10765348B2 (en) 2016-04-08 2020-09-08 Medtronic Minimed, Inc. Sensor and transmitter product
US10765369B2 (en) 2016-04-08 2020-09-08 Medtronic Minimed, Inc. Analyte sensor
WO2017183030A1 (en) 2016-04-20 2017-10-26 Glusense Ltd. Fret-based glucose-detection molecules
US10589038B2 (en) 2016-04-27 2020-03-17 Medtronic Minimed, Inc. Set connector systems for venting a fluid reservoir
US10324058B2 (en) 2016-04-28 2019-06-18 Medtronic Minimed, Inc. In-situ chemistry stack for continuous glucose sensors
US10426389B2 (en) 2016-04-28 2019-10-01 Medtronic Minimed, Inc. Methods, systems, and devices for electrode capacitance calculation and application
US9970893B2 (en) 2016-04-28 2018-05-15 Medtronic Minimed, Inc. Methods, systems, and devices for electrode capacitance calculation and application
US9968737B2 (en) 2016-05-26 2018-05-15 Medtronic Minimed, Inc. Systems for set connector assembly with lock
US10086133B2 (en) 2016-05-26 2018-10-02 Medtronic Minimed, Inc. Systems for set connector assembly with lock
US10086134B2 (en) 2016-05-26 2018-10-02 Medtronic Minimed, Inc. Systems for set connector assembly with lock
US11179078B2 (en) 2016-06-06 2021-11-23 Medtronic Minimed, Inc. Polycarbonate urea/urethane polymers for use with analyte sensors
US11134872B2 (en) 2016-06-06 2021-10-05 Medtronic Minimed, Inc. Thermally stable glucose limiting membrane for glucose sensors
CN109715066B (zh) * 2016-07-20 2022-04-05 巴尔的摩马里兰大学 基于硅氧烷水凝胶的荧光测定和接触镜片
US10449291B2 (en) 2016-09-06 2019-10-22 Medtronic Minimed, Inc. Pump clip for a fluid infusion device
CN112738700A (zh) 2016-09-09 2021-04-30 伊尔兰斯公司 智能镜系统和方法
WO2018093733A1 (en) 2016-11-15 2018-05-24 Earlens Corporation Improved impression procedure
US10861591B2 (en) 2016-12-21 2020-12-08 Medtronic Minimed, Inc. Infusion systems and methods for pattern-based therapy adjustments
CN115505280A (zh) 2016-12-21 2022-12-23 普罗菲尤萨股份有限公司 可聚合的近红外染料
US10709834B2 (en) 2016-12-21 2020-07-14 Medtronic Minimed, Inc. Medication fluid infusion set component with integrated physiological analyte sensor, and corresponding fluid infusion device
US10272201B2 (en) 2016-12-22 2019-04-30 Medtronic Minimed, Inc. Insertion site monitoring methods and related infusion devices and systems
WO2018119400A1 (en) 2016-12-22 2018-06-28 Profusa, Inc. System and single-channel luminescent sensor for and method of determining analyte value
US11197949B2 (en) 2017-01-19 2021-12-14 Medtronic Minimed, Inc. Medication infusion components and systems
US10821225B2 (en) 2017-01-20 2020-11-03 Medtronic Minimed, Inc. Cannulas for drug delivery devices
US10552580B2 (en) 2017-02-07 2020-02-04 Medtronic Minimed, Inc. Infusion system consumables and related calibration methods
US10646649B2 (en) 2017-02-21 2020-05-12 Medtronic Minimed, Inc. Infusion devices and fluid identification apparatuses and methods
US11986288B2 (en) 2017-03-06 2024-05-21 Medtronic Minimed, Inc. Colorometric sensor for the non-invasive screening of glucose in sweat in pre and type 2 diabetes
US11134868B2 (en) 2017-03-17 2021-10-05 Medtronic Minimed, Inc. Metal pillar device structures and methods for making and using them in electrochemical and/or electrocatalytic applications
US11064951B2 (en) 2017-03-24 2021-07-20 Medtronic Minimed, Inc. Patient data management systems and querying methods
US10792378B2 (en) 2017-04-28 2020-10-06 Medtronics Minimed, Inc. Using a blue-shifted reference dye in an optical glucose assay
US10543288B2 (en) 2017-04-28 2020-01-28 Medtronic Minimed, Inc. Modified-dextrans for use in optical glucose assays
US11512384B2 (en) 2017-05-11 2022-11-29 Medtronic Minimed, Inc. Analyte sensors and methods for fabricating analyte sensors
CN108968976B (zh) 2017-05-31 2022-09-13 心脏起搏器股份公司 具有化学传感器的植入式医疗设备
US10856784B2 (en) 2017-06-30 2020-12-08 Medtronic Minimed, Inc. Sensor initialization methods for faster body sensor response
CN109381195B (zh) 2017-08-10 2023-01-10 心脏起搏器股份公司 包括电解质传感器融合的系统和方法
CN109419515B (zh) 2017-08-23 2023-03-24 心脏起搏器股份公司 具有分级激活的可植入化学传感器
US11412960B2 (en) 2017-08-28 2022-08-16 Medtronic Minimed, Inc. Pedestal for sensor assembly packaging and sensor introducer removal
US10596295B2 (en) 2017-08-28 2020-03-24 Medtronic Minimed, Inc. Adhesive patch arrangement for a physiological characteristic sensor, and related sensor assembly
US11344235B2 (en) 2017-09-13 2022-05-31 Medtronic Minimed, Inc. Methods, systems, and devices for calibration and optimization of glucose sensors and sensor output
US10874300B2 (en) 2017-09-26 2020-12-29 Medtronic Minimed, Inc. Waferscale physiological characteristic sensor package with integrated wireless transmitter
US10525244B2 (en) 2017-09-28 2020-01-07 Medtronic Minimed, Inc. Microneedle arrays and methods for fabricating microneedle arrays
US10524730B2 (en) 2017-09-28 2020-01-07 Medtronic Minimed, Inc. Medical devices with microneedle arrays and methods for operating such medical devices
CN212438615U (zh) 2017-10-24 2021-02-02 德克斯康公司 可穿戴设备
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
US11676734B2 (en) 2017-11-15 2023-06-13 Medtronic Minimed, Inc. Patient therapy management system that leverages aggregated patient population data
CN109864746B (zh) 2017-12-01 2023-09-29 心脏起搏器股份公司 用于医学装置的多模式分析物传感器
CN109864747B (zh) 2017-12-05 2023-08-25 心脏起搏器股份公司 多模式分析物传感器光电子接口
US11213230B2 (en) 2017-12-13 2022-01-04 Medtronic Minimed, Inc. Optional sensor calibration in continuous glucose monitoring
US11471082B2 (en) 2017-12-13 2022-10-18 Medtronic Minimed, Inc. Complex redundancy in continuous glucose monitoring
US11439352B2 (en) 2018-01-17 2022-09-13 Medtronic Minimed, Inc. Medical device with adhesive patch longevity
US11186859B2 (en) 2018-02-07 2021-11-30 Medtronic Minimed, Inc. Multilayer electrochemical analyte sensors and methods for making and using them
US11583213B2 (en) 2018-02-08 2023-02-21 Medtronic Minimed, Inc. Glucose sensor electrode design
US11220735B2 (en) 2018-02-08 2022-01-11 Medtronic Minimed, Inc. Methods for controlling physical vapor deposition metal film adhesion to substrates and surfaces
AU2019218260B2 (en) 2018-02-09 2022-01-06 W. L. Gore & Associates, Inc. Implantable access chamber and associated methods of use
WO2019173470A1 (en) 2018-03-07 2019-09-12 Earlens Corporation Contact hearing device and retention structure materials
US11672446B2 (en) 2018-03-23 2023-06-13 Medtronic Minimed, Inc. Insulin delivery recommendations based on nutritional information
WO2019199680A1 (en) 2018-04-09 2019-10-17 Earlens Corporation Dynamic filter
US11147919B2 (en) 2018-04-23 2021-10-19 Medtronic Minimed, Inc. Methodology to recommend and implement adjustments to a fluid infusion device of a medication delivery system
US11158413B2 (en) 2018-04-23 2021-10-26 Medtronic Minimed, Inc. Personalized closed loop medication delivery system that utilizes a digital twin of the patient
US20190341149A1 (en) 2018-05-07 2019-11-07 Medtronic Minimed, Inc. Augmented reality guidance for medical devices
WO2019222499A1 (en) 2018-05-16 2019-11-21 Medtronic Minimed, Inc. Thermally stable glucose limiting membrane for glucose sensors
US11761077B2 (en) 2018-08-01 2023-09-19 Medtronic Minimed, Inc. Sputtering techniques for biosensors
US11122697B2 (en) 2018-08-07 2021-09-14 Medtronic Minimed, Inc. Method of fabricating an electronic medical device, including overmolding an assembly with thermoplastic material
US11021731B2 (en) 2018-08-23 2021-06-01 Medtronic Minimed, Inc. Analyte sensing layers, analyte sensors and methods for fabricating the same
US10828419B2 (en) 2018-09-04 2020-11-10 Medtronic Minimed, Inc. Infusion set with pivoting metal cannula and strain relief
US11547799B2 (en) 2018-09-20 2023-01-10 Medtronic Minimed, Inc. Patient day planning systems and methods
US10894126B2 (en) 2018-09-28 2021-01-19 Medtronic Minimed, Inc. Fluid infusion system that automatically determines and delivers a correction bolus
US11071821B2 (en) 2018-09-28 2021-07-27 Medtronic Minimed, Inc. Insulin infusion device with efficient confirmation routine for blood glucose measurements
US10980942B2 (en) 2018-09-28 2021-04-20 Medtronic Minimed, Inc. Infusion devices and related meal bolus adjustment methods
US11097052B2 (en) 2018-09-28 2021-08-24 Medtronic Minimed, Inc. Insulin infusion device with configurable target blood glucose value for automatic basal insulin delivery operation
US10946140B2 (en) 2018-10-11 2021-03-16 Medtronic Minimed, Inc. Systems and methods for measurement of fluid delivery
US20200116748A1 (en) 2018-10-11 2020-04-16 Medtronic Minimed, Inc. Systems and methods for measurement of fluid delivery
US11367517B2 (en) 2018-10-31 2022-06-21 Medtronic Minimed, Inc. Gesture-based detection of a physical behavior event based on gesture sensor data and supplemental information from at least one external source
US11367516B2 (en) 2018-10-31 2022-06-21 Medtronic Minimed, Inc. Automated detection of a physical behavior event and corresponding adjustment of a medication dispensing system
US20200289373A1 (en) 2018-10-31 2020-09-17 Medtronic Minimed, Inc. Automated detection of a physical behavior event and corresponding adjustment of a physiological characteristic sensor device
US11363986B2 (en) 2018-10-31 2022-06-21 Medtronic Minimed, Inc. Automated detection of a physical behavior event and corresponding adjustment of a medication dispensing system
US11382541B2 (en) 2018-11-16 2022-07-12 Medtronic Minimed, Inc. Miniaturized analyte sensor
US11540750B2 (en) 2018-12-19 2023-01-03 Medtronic Minimed, Inc Systems and methods for physiological characteristic monitoring
US11439752B2 (en) 2019-02-01 2022-09-13 Medtronic Minimed, Inc. Methods and devices for occlusion detection using actuator sensors
US11389587B2 (en) 2019-02-06 2022-07-19 Medtronic Minimed, Inc. Patient monitoring systems and related presentation methods
US11191899B2 (en) 2019-02-12 2021-12-07 Medtronic Minimed, Inc. Infusion systems and related personalized bolusing methods
US10760969B1 (en) 2019-02-28 2020-09-01 Biospex, Inc. Fluorescence and systemic noise reduction in time-gated spectroscopy
US11311215B2 (en) 2019-04-04 2022-04-26 Medtronic Minimed, Inc. Measurement of device materials using non-Faradaic electrochemical impedance spectroscopy
US11986629B2 (en) 2019-06-11 2024-05-21 Medtronic Minimed, Inc. Personalized closed loop optimization systems and methods
US11317867B2 (en) 2019-04-23 2022-05-03 Medtronic Minimed, Inc. Flexible physiological characteristic sensor assembly
US11224361B2 (en) 2019-04-23 2022-01-18 Medtronic Minimed, Inc. Flexible physiological characteristic sensor assembly
US10939488B2 (en) 2019-05-20 2021-03-02 Medtronic Minimed, Inc. Method and system for controlling communication between devices of a wireless body area network for an medical device system
US11844925B2 (en) 2019-06-06 2023-12-19 Medtronic Minimed, Inc. Fluid infusion systems
US11448611B2 (en) 2019-07-03 2022-09-20 Medtronic Minimed, Inc. Structurally reinforced sensor and method for manufacturing the same
US11454540B2 (en) 2019-07-12 2022-09-27 Biospex, Inc. Wearable spectroscopy using filtered sensor
US11326944B2 (en) * 2019-07-12 2022-05-10 Biospex, Inc. Wearable spectrometer with filtered sensor
US11617828B2 (en) 2019-07-17 2023-04-04 Medtronic Minimed, Inc. Reservoir connection interface with detectable signature
US11718865B2 (en) 2019-07-26 2023-08-08 Medtronic Minimed, Inc. Methods to improve oxygen delivery to implantable sensors
US11523757B2 (en) 2019-08-01 2022-12-13 Medtronic Minimed, Inc. Micro-pillar working electrodes design to reduce backflow of hydrogen peroxide in glucose sensor
US11883208B2 (en) 2019-08-06 2024-01-30 Medtronic Minimed, Inc. Machine learning-based system for estimating glucose values based on blood glucose measurements and contextual activity data
US20220039755A1 (en) 2020-08-06 2022-02-10 Medtronic Minimed, Inc. Machine learning-based system for estimating glucose values
US11617522B2 (en) 2019-08-06 2023-04-04 Medtronic Minimed, Inc. Sensor inserter with disposal lockout state
US11724045B2 (en) 2019-08-21 2023-08-15 Medtronic Minimed, Inc. Connection of a stopper and piston in a fluid delivery device
US11571515B2 (en) 2019-08-29 2023-02-07 Medtronic Minimed, Inc. Controlling medical device operation and features based on detected patient sleeping status
US11565044B2 (en) 2019-09-12 2023-01-31 Medtronic Minimed, Inc. Manufacturing controls for sensor calibration using fabrication measurements
US11654235B2 (en) 2019-09-12 2023-05-23 Medtronic Minimed, Inc. Sensor calibration using fabrication measurements
US11241537B2 (en) 2019-09-20 2022-02-08 Medtronic Minimed, Inc. Contextual personalized closed-loop adjustment methods and systems
US11213623B2 (en) 2019-09-20 2022-01-04 Medtronic Minimed, Inc. Infusion systems and related personalized bolusing methods
US11511099B2 (en) 2019-10-08 2022-11-29 Medtronic Minimed, Inc. Apparatus for detecting mating of a cap with a fluid delivery device and method
US11638545B2 (en) 2019-10-16 2023-05-02 Medtronic Minimed, Inc. Reducing sensor foreign body response via high surface area metal structures
US11496083B2 (en) 2019-11-15 2022-11-08 Medtronic Minimed, Inc. Devices and methods for controlling electromechanical actuators
US11944784B2 (en) 2019-11-18 2024-04-02 Medtronic Minimed, Inc. Combined analyte sensor and infusion set
US11324881B2 (en) 2019-11-21 2022-05-10 Medtronic Minimed, Inc. Systems for wearable infusion port and associated pump
US11559624B2 (en) 2019-11-21 2023-01-24 Medtronic Minimed, Inc. Systems for wearable infusion port and associated pump
US11670425B2 (en) 2019-12-09 2023-06-06 Medtronic Minimed, Inc. Translation modeling methods and systems for simulating sensor measurements
US11786655B2 (en) 2019-12-13 2023-10-17 Medtronic Minimed, Inc. Context-sensitive predictive operation of a medication delivery system in response to gesture-indicated activity changes
US20210183522A1 (en) 2019-12-13 2021-06-17 Medtronic Minimed, Inc. Method and system for training a mathematical model of a user based on data received from a discrete insulin therapy system
US11938301B2 (en) 2019-12-13 2024-03-26 Medtronic Minimed, Inc. Controlling medication delivery system operation and features based on automatically detected muscular movements
US11488700B2 (en) 2019-12-13 2022-11-01 Medtronic Minimed, Inc. Medical device configuration procedure guidance responsive to detected gestures
US11375955B2 (en) 2019-12-18 2022-07-05 Medtronic Minimed, Inc. Systems for skin patch gravity resistance
US11690573B2 (en) 2019-12-18 2023-07-04 Medtronic Minimed, Inc. Systems for skin patch gravity resistance
US11821022B2 (en) 2019-12-23 2023-11-21 Medtronic Minimed, Inc. Ethylene oxide absorption layer for analyte sensing and method
US11244753B2 (en) 2020-01-30 2022-02-08 Medtronic Minimed, Inc. Activity monitoring systems and methods
US11957488B2 (en) 2020-02-07 2024-04-16 Medtronic Minimed, Inc. Systems for medical device breathability
US11833327B2 (en) 2020-03-06 2023-12-05 Medtronic Minimed, Inc. Analyte sensor configuration and calibration based on data collected from a previously used analyte sensor
USD958167S1 (en) 2020-03-23 2022-07-19 Companion Medical, Inc. Display screen with graphical user interface
USD958817S1 (en) 2020-03-31 2022-07-26 Medtronic Minimed, Inc. Display screen with graphical user interface
US11596359B2 (en) 2020-04-09 2023-03-07 Medtronic Minimed, Inc. Methods and systems for mitigating sensor error propagation
US11690955B2 (en) 2020-04-23 2023-07-04 Medtronic Minimed, Inc. Continuous analyte sensor quality measures and related therapy actions for an automated therapy delivery system
US11583631B2 (en) 2020-04-23 2023-02-21 Medtronic Minimed, Inc. Intuitive user interface features and related functionality for a therapy delivery system
US11272884B2 (en) 2020-06-04 2022-03-15 Medtronic Minimed, Inc. Liner for adhesive skin patch
US11960311B2 (en) 2020-07-28 2024-04-16 Medtronic Minimed, Inc. Linear voltage regulator with isolated supply current
US11650248B2 (en) 2020-07-28 2023-05-16 Medtronic Minimed, Inc. Electrical current measurement system
US11445807B2 (en) 2020-07-31 2022-09-20 Medtronic Minimed, Inc. Pump clip with tube clamp for a fluid infusion device
US11839743B2 (en) 2020-10-07 2023-12-12 Medtronic Minimed, Inc. Graphic user interface for automated infusate delivery
US11737783B2 (en) 2020-10-16 2023-08-29 Medtronic Minimed, Inc. Disposable medical device introduction system
US11806503B2 (en) 2020-10-29 2023-11-07 Medtronic Minimed, Inc. Removable wearable device and related attachment methods
US11844930B2 (en) 2020-10-29 2023-12-19 Medtronic Minimed, Inc. User-mountable electronic device with accelerometer-based activation feature
US11534086B2 (en) 2020-10-30 2022-12-27 Medtronic Minimed, Inc. Low-profile wearable medical device
US11951281B2 (en) 2020-11-11 2024-04-09 Medtronic Minimed, Inc. Fluid conduit insertion devices
CN116801804A (zh) 2021-01-29 2023-09-22 美敦力迷你迈德公司 可与分析物传感器一起使用的干扰抑制膜
EP4288971A1 (de) 2021-02-02 2023-12-13 Medtronic MiniMed, Inc. Dynamische anpassungen physiologischer daten
US11904146B2 (en) 2021-06-08 2024-02-20 Medtronic Minimed, Inc. Medicine injection devices, systems, and methods for medicine administration and tracking
US11792714B2 (en) 2021-06-16 2023-10-17 Medtronic Minimed, Inc. Medicine administration in dynamic networks
US11587742B1 (en) 2021-09-02 2023-02-21 Medtronic Minimed, Inc. Ingress-tolerant input devices
US11817285B2 (en) 2021-09-02 2023-11-14 Medtronic Minimed, Inc. Ingress-tolerant input devices comprising sliders
US20230113175A1 (en) 2021-10-08 2023-04-13 Medtronic Minimed, Inc. Immunosuppressant releasing coatings
US11896447B2 (en) 2022-03-14 2024-02-13 Medtronic Minimed, Inc. Safeguards against separation from portable medicine delivery devices
US11997806B2 (en) 2022-04-26 2024-05-28 Medtronic Minimed, Inc. Energy management based on an open switch configuration
US20240023849A1 (en) 2022-07-20 2024-01-25 Medtronic Minimed, Inc. Acrylate hydrogel membrane for dual function of diffusion limiting membrane as well as attenuation to the foreign body response
US20240158827A1 (en) 2022-10-28 2024-05-16 Medtronic Minimed, Inc. Enzyme mediator functionalized polymers for use with analyte sensors

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3912595A (en) * 1974-02-25 1975-10-14 Us Health Method of purifying enzymes using boronic acids covalently bonded to an insoluble support
US4401122A (en) * 1979-08-02 1983-08-30 Children's Hospital Medical Center Cutaneous methods of measuring body substances
US4371374A (en) * 1980-11-17 1983-02-01 The Rockefeller University Monitoring metabolic control in diabetic patients by measuring glycosylated amino acids and peptides in urine
US4496722A (en) * 1981-05-01 1985-01-29 The Children's Medical Center Corporation Reporter compounds
US4428366A (en) * 1981-05-06 1984-01-31 Alfred B. Kurtz Electromagnetic apparatus and method for the reduction of serum glucose levels
US4655225A (en) * 1985-04-18 1987-04-07 Kurabo Industries Ltd. Spectrophotometric method and apparatus for the non-invasive
US5034189A (en) * 1985-08-27 1991-07-23 The Regents Of The University Of California Fluorescent probe for rapid measurement of analyte concentration
US4680268A (en) * 1985-09-18 1987-07-14 Children's Hospital Medical Center Implantable gas-containing biosensor and method for measuring an analyte such as glucose
US4875486A (en) * 1986-09-04 1989-10-24 Advanced Techtronics, Inc. Instrument and method for non-invasive in vivo testing for body fluid constituents
US5240602A (en) * 1987-06-08 1993-08-31 Chromatochem, Inc. Chromatographic material
US4805623A (en) * 1987-09-04 1989-02-21 Vander Corporation Spectrophotometric method for quantitatively determining the concentration of a dilute component in a light- or other radiation-scattering environment
US4974929A (en) * 1987-09-22 1990-12-04 Baxter International, Inc. Fiber optical probe connector for physiologic measurement devices
US4882492A (en) * 1988-01-19 1989-11-21 Biotronics Associates, Inc. Non-invasive near infrared measurement of blood analyte concentrations
US5362307A (en) * 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
KR970011449B1 (ko) * 1988-01-29 1997-07-11 더 리전트 오브 디 유니버시티 오브 캘리포니아 이온전기 영동형 비침입 검체 채취 또는 이송 장치 및 방법
US5086229A (en) * 1989-01-19 1992-02-04 Futrex, Inc. Non-invasive measurement of blood glucose
US5077476A (en) * 1990-06-27 1991-12-31 Futrex, Inc. Instrument for non-invasive measurement of blood glucose
US5028787A (en) * 1989-01-19 1991-07-02 Futrex, Inc. Non-invasive measurement of blood glucose
US5112124A (en) * 1990-04-19 1992-05-12 Worcester Polytechnic Institute Method and apparatus for measuring the concentration of absorbing substances
US5101814A (en) * 1989-08-11 1992-04-07 Palti Yoram Prof System for monitoring and controlling blood glucose
US5512246A (en) 1989-09-21 1996-04-30 Anthony P. Russell Method and means for detecting polyhydroxyl compounds
US5137833A (en) 1989-09-21 1992-08-11 Russell Anthony P Method for detecting polyhydroxyl compounds
US6040194A (en) 1989-12-14 2000-03-21 Sensor Technologies, Inc. Methods and device for detecting and quantifying substances in body fluids
US5342789A (en) * 1989-12-14 1994-08-30 Sensor Technologies, Inc. Method and device for detecting and quantifying glucose in body fluids
US5070874A (en) * 1990-01-30 1991-12-10 Biocontrol Technology, Inc. Non-invasive determination of glucose concentration in body of patients
US5054487A (en) * 1990-02-02 1991-10-08 Boston Advanced Technologies, Inc. Laser systems for material analysis based on reflectance ratio detection
EP0447196A1 (de) * 1990-03-16 1991-09-18 Hewlett-Packard Company Boronsaure Farbstoffe
US5196709A (en) * 1991-05-03 1993-03-23 University Of Maryland Systems Fluorometry method and apparatus using a semiconductor laser diode as a light source
US5203328A (en) * 1991-07-17 1993-04-20 Georgia Tech Research Corporation Apparatus and methods for quantitatively measuring molecular changes in the ocular lens
US5281825A (en) * 1991-09-05 1994-01-25 The University Of Maryland School Of Medicine Phase fluorometry using a modulated electroluminescent lamp as a light source
US5209838A (en) * 1991-10-07 1993-05-11 Aluminum Company Of America Purification of an oil-containing liquid using a surface treated permeable inorganic membrane
US5353790A (en) * 1992-01-17 1994-10-11 Board Of Regents, The University Of Texas System Method and apparatus for optical measurement of bilirubin in tissue
US5246867A (en) * 1992-01-17 1993-09-21 University Of Maryland At Baltimore Determination and quantification of saccharides by luminescence lifetimes and energy transfer
US5284140A (en) * 1992-02-11 1994-02-08 Eli Lilly And Company Acrylic copolymer membranes for biosensors
US6256522B1 (en) 1992-11-23 2001-07-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Sensors for continuous monitoring of biochemicals and related method
US5409835A (en) * 1992-12-30 1995-04-25 The University Of Maryland At Baltimore Long-wavelength fluorescent probe compounds for calcium ions and their use in ratiometrically measuring calcium ion concentrations
US5593899A (en) * 1993-02-25 1997-01-14 Trustees Of The University Of Pennsylvania Device and method for measuring tissue oxygenation through the skin using oxygen dependent quenching of phosphorescence
GB2284809B (en) * 1993-11-07 1998-04-29 Japan Res Dev Corp A fluorescent phenylboronic acid suitable for use in the detection of saccharides
US5445611A (en) * 1993-12-08 1995-08-29 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal delivery with ultrasound and chemical enhancers
US5458140A (en) * 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5515864A (en) * 1994-04-21 1996-05-14 Zuckerman; Ralph Method and apparatus for the in vivo measurement of oxygen concentration levels by the indirect determination of fluoescence lifetime
US5605152A (en) * 1994-07-18 1997-02-25 Minimed Inc. Optical glucose sensor
JP2799837B2 (ja) * 1995-03-03 1998-09-21 科学技術振興事業団 ビナフチル基を有するボロン酸化合物
US5628310A (en) * 1995-05-19 1997-05-13 Joseph R. Lakowicz Method and apparatus to perform trans-cutaneous analyte monitoring
US6002954A (en) * 1995-11-22 1999-12-14 The Regents Of The University Of California Detection of biological molecules using boronate-based chemical amplification and optical sensors
US6011984A (en) * 1995-11-22 2000-01-04 Minimed Inc. Detection of biological molecules using chemical amplification and optical sensors
AT409306B (de) 1997-10-03 2002-07-25 Hoffmann La Roche Optisch chemischer sensor
US6254831B1 (en) 1998-01-21 2001-07-03 Bayer Corporation Optical sensors with reflective materials
TWI227323B (en) 1998-03-11 2005-02-01 Sensors For Med & Science Inc Detection of analytes by fluorescent lanthanide metal chelate complexes containing substituted ligands
US6366793B1 (en) 1999-09-10 2002-04-02 Beckman Coulter, Inc. Minimally invasive methods for measuring analtes in vivo
US20020119581A1 (en) 2001-01-05 2002-08-29 Daniloff George Y. Detection of analytes

Also Published As

Publication number Publication date
JP2000500656A (ja) 2000-01-25
US6319540B1 (en) 2001-11-20
CA2235738A1 (en) 1997-05-29
US6804544B2 (en) 2004-10-12
EP0862648B1 (de) 2004-10-06
CA2235738C (en) 2005-07-26
DE69633573D1 (de) 2004-11-11
DE69633573T2 (de) 2005-10-06
WO1997019188A1 (en) 1997-05-29
US6011984A (en) 2000-01-04
US20020018843A1 (en) 2002-02-14
AU1058297A (en) 1997-06-11
EP0862648A1 (de) 1998-09-09

Similar Documents

Publication Publication Date Title
ATE278801T1 (de) Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor
Laurell A continuous glucose monitoring system based on microdialysis
ATE258028T1 (de) Signalverarbeitung zur messung von physiologischen analyten
US8965470B2 (en) Micro-invasive method for painless detection of analytes in extracellular space
CA2440854A1 (en) Subcutaneous analyte sensor
DK0680727T3 (da) Analysesystem til overvågning af koncentrationen af en analyt i en patients blod
CA2332112A1 (en) Monitoring of physiological analytes
CA2065890A1 (en) Quantitative Analysis Method and Its System Using a Disposable Sensor
EP1956365A3 (de) Optische Fühler
CA2137878A1 (en) Photosensor with multiple light sources
WO1999002956A3 (en) Method and devices for laser induced fluorescence attenuation spectroscopy (lifas)
FR2830325B1 (fr) Dispositif de mesure des caracteristiques d'absorption lumineuse d'un echantillon de tissu biologique, procede de mesure associe, et applications dans le domaine de l'analyse vegetale et le domaine medical
DE69808071D1 (de) Nachweistest unter benutzung von magnetteilchen
DE69833660D1 (de) Nukleinsäuresonden zur detektion von candida-spezies
ES2119165T3 (es) Nueva actividad de cofactor anticoagulante.
EP0329458A3 (de) Verfahren und Gerät zur Messung von Analyten
DE3673768D1 (de) Mittel zur bestimmung von peroxidase-aktivitaet, verfahren zur herstellung und seine verwendung.
RU94041262A (ru) Способ прогнозирования течения псориаза
ATE405575T1 (de) Verwendung von an polyamid gebundenen nukleinsäure-oligomeren zur erzeugung einer biologischen reaktion
ES2102970A1 (es) Electroinmunoensayos analiticos y electroensayos de reconocimiento biologico.
Owen Hungary—Future of MEBC: In BIOSYSTEMS (35/2–3 (233–237) 1995) G. Biczo of the Hungarian Academy of Sciences reports on “The future of MEBC: Panel discussion”
Wimmerova et al. Enzyme Biosensors for Plasma Histamine Assay
IT1275887B1 (it) Procedimento per rilevare e determinare quantitativamente sostanze di interesse biologico e/o medico, enzimi e simili
NO991338L (no) FremgangsmÕter for in vitro-bestemmelse av erytropoietinbioaktivitet

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties