AR204004A1 - PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES - Google Patents

PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES

Info

Publication number
AR204004A1
AR204004A1 AR253105A AR25310574A AR204004A1 AR 204004 A1 AR204004 A1 AR 204004A1 AR 253105 A AR253105 A AR 253105A AR 25310574 A AR25310574 A AR 25310574A AR 204004 A1 AR204004 A1 AR 204004A1
Authority
AR
Argentina
Prior art keywords
leurocristine
leurosidine
vinblastin
procedures
derivatives
Prior art date
Application number
AR253105A
Other languages
Spanish (es)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of AR204004A1 publication Critical patent/AR204004A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
AR253105A 1973-04-02 1974-01-01 PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES AR204004A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34727573A 1973-04-02 1973-04-02

Publications (1)

Publication Number Publication Date
AR204004A1 true AR204004A1 (en) 1975-11-12

Family

ID=23363051

Family Applications (2)

Application Number Title Priority Date Filing Date
AR253105A AR204004A1 (en) 1973-04-02 1974-01-01 PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES
AR257228A AR203882A1 (en) 1973-04-02 1975-01-08 PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES

Family Applications After (1)

Application Number Title Priority Date Filing Date
AR257228A AR203882A1 (en) 1973-04-02 1975-01-08 PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES

Country Status (28)

Country Link
JP (2) JPS5919117B2 (en)
AR (2) AR204004A1 (en)
AT (1) AT340605B (en)
BE (1) BE813168A (en)
BG (3) BG22831A3 (en)
CA (1) CA1042428A (en)
CH (1) CH603669A5 (en)
CS (1) CS185223B2 (en)
CY (1) CY1044A (en)
DD (1) DD113538A5 (en)
DE (1) DE2415980A1 (en)
DK (1) DK141511B (en)
ES (2) ES424882A1 (en)
FR (1) FR2223044B1 (en)
GB (1) GB1463575A (en)
HK (1) HK20180A (en)
HU (1) HU171572B (en)
IE (1) IE39071B1 (en)
IL (1) IL44415A (en)
KE (1) KE3028A (en)
MY (1) MY8100025A (en)
NL (1) NL181079C (en)
PH (1) PH13623A (en)
RO (2) RO73524B (en)
SE (1) SE416206B (en)
SU (4) SU731900A3 (en)
YU (3) YU39719B (en)
ZA (1) ZA741674B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (en) * 1976-09-08 1982-07-07 Lilly Co Eli
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30560E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
US4203898A (en) 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
LU83822A1 (en) * 1981-12-08 1983-09-01 Omnichem Sa N- (VINBLASTINOYL-23) DERIVATIVES OF AMINO ACIDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
OA06421A (en) * 1980-06-10 1981-09-30 Omnium Chimique Sa Process for the preparation of N- (vinblastinoyl-23) derivatives of amino acids and peptides.
FR2623504B1 (en) * 1987-11-25 1990-03-09 Adir NOVEL N- (VINBLASTINOYL-23) DERIVATIVES OF 1-AMINO METHYLPHOSPHONIC ACID, PROCESSES FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
HUT76925A (en) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bis-indole derivatives, process for the preparation thereof and pharmaceutical compositions containing them
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules
KR101345002B1 (en) 2005-01-21 2013-12-31 아스텍스 테라퓨틱스 리미티드 Pharmaceutical compounds
JP5177429B2 (en) 2005-07-18 2013-04-03 バイパー サイエンシズ，インコーポレイティド Cancer treatment
CN101522609A (en) 2006-09-05 2009-09-02 彼帕科学公司 Treatment of cancer
US7994222B2 (en) 2006-09-05 2011-08-09 Bipar Sciences, Inc. Monitoring of the inhibition of fatty acid synthesis by iodo-nitrobenzamide compounds
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
US7732491B2 (en) 2007-11-12 2010-06-08 Bipar Sciences, Inc. Treatment of breast cancer with a PARP inhibitor alone or in combination with anti-tumor agents
JP6250710B2 (en) * 2013-04-19 2017-12-20 曁南大学 Preparation method of vinblastine derivative
CN113456797B (en) * 2021-06-18 2024-03-08 暨南大学 Application of vinblastine derivatives in preparation of medicines for treating osteosarcoma and/or soft tissue sarcoma

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine

Also Published As

Publication number Publication date
GB1463575A (en) 1977-02-02
DD113538A5 (en) 1975-06-12
RO77533A (en) 1982-02-01
NL7404423A (en) 1974-10-04
AT340605B (en) 1977-12-27
YU81774A (en) 1982-05-31
CY1044A (en) 1980-08-01
NL181079B (en) 1987-01-16
IE39071L (en) 1974-10-02
IE39071B1 (en) 1978-08-02
RO73524A (en) 1984-10-31
FR2223044A1 (en) 1974-10-25
FR2223044B1 (en) 1978-06-30
YU113880A (en) 1982-05-31
MY8100025A (en) 1981-12-31
ES446571A1 (en) 1977-06-16
SE416206B (en) 1980-12-08
CA1042428A (en) 1978-11-14
YU39719B (en) 1985-04-30
JPS59193895A (en) 1984-11-02
JPS49128000A (en) 1974-12-07
AR203882A1 (en) 1975-10-31
HU171572B (en) 1978-02-28
IL44415A0 (en) 1974-06-30
DE2415980C2 (en) 1989-11-09
DK141511C (en) 1980-09-29
DE2415980A1 (en) 1974-10-10
YU39876B (en) 1985-04-30
KE3028A (en) 1980-03-28
IL44415A (en) 1978-08-31
SU731900A3 (en) 1980-04-30
SU784783A3 (en) 1980-11-30
JPS5919117B2 (en) 1984-05-02
AU6671974A (en) 1975-09-18
BG22831A3 (en) 1977-04-20
SU623522A3 (en) 1978-09-05
PH13623A (en) 1980-08-07
ZA741674B (en) 1975-10-29
RO73524B (en) 1984-11-30
YU39875B (en) 1985-04-30
JPS6033837B2 (en) 1985-08-05
BE813168A (en) 1974-10-02
BG21612A3 (en) 1976-07-20
ATA267974A (en) 1977-04-15
ES424882A1 (en) 1976-12-16
SU652896A3 (en) 1979-03-15
HK20180A (en) 1980-04-25
NL181079C (en) 1987-06-16
DK141511B (en) 1980-04-08
CH603669A5 (en) 1978-08-31
CS185223B2 (en) 1978-09-15
BG21235A3 (en) 1976-03-20
YU113980A (en) 1982-05-31

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