AR086249A1 - COMPOSITIONS OF VAGINAL ADMINISTRATION FAST DISSOLUTION TABLETS - Google Patents
COMPOSITIONS OF VAGINAL ADMINISTRATION FAST DISSOLUTION TABLETSInfo
- Publication number
- AR086249A1 AR086249A1 ARP120101551A ARP120101551A AR086249A1 AR 086249 A1 AR086249 A1 AR 086249A1 AR P120101551 A ARP120101551 A AR P120101551A AR P120101551 A ARP120101551 A AR P120101551A AR 086249 A1 AR086249 A1 AR 086249A1
- Authority
- AR
- Argentina
- Prior art keywords
- vaginal administration
- compositions
- rapidly
- vaginal
- fast dissolution
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Virology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Transplantation (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Rheumatology (AREA)
Abstract
Reivindicación 1: Una composición farmacéutica en la forma de microgránulos de disolución rápida de administración vaginal que incluye: (a) una cantidad terapéuticamente efectiva de una droga vaginalmente activa; (b) un excipiente polimérico con la propiedad dual de actuar como aglutinante, al igual que como material bioadhesivo; (c) un alcohol de azúcar, un sacárido o una combinación de los mismos; y (d) un disgregante; donde la composición farmacéutica se desintegra rápidamente luego de su inserción en la cavidad vaginal de un paciente o sujeto y forma una suspensión viscosa que contiene la droga que se esparce rápida y ampliamente y recubre la mucosa vaginal.Claim 1: A pharmaceutical composition in the form of rapidly dissolving vaginal administration microgranules that includes: (a) a therapeutically effective amount of a vaginally active drug; (b) a polymeric excipient with the dual property of acting as a binder, as well as as a bioadhesive material; (c) a sugar alcohol, a saccharide or a combination thereof; and (d) a disintegrant; where the pharmaceutical composition disintegrates rapidly after insertion into the vaginal cavity of a patient or subject and forms a viscous suspension containing the drug that spreads rapidly and widely and covers the vaginal mucosa.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161481582P | 2011-05-02 | 2011-05-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR086249A1 true AR086249A1 (en) | 2013-11-27 |
Family
ID=47108022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP120101551A AR086249A1 (en) | 2011-05-02 | 2012-05-02 | COMPOSITIONS OF VAGINAL ADMINISTRATION FAST DISSOLUTION TABLETS |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP2704694A4 (en) |
JP (1) | JP6154803B2 (en) |
KR (2) | KR20160112012A (en) |
CN (1) | CN103596556A (en) |
AP (1) | AP2013007268A0 (en) |
AR (1) | AR086249A1 (en) |
AU (1) | AU2012250862B2 (en) |
CA (1) | CA2839790A1 (en) |
CL (1) | CL2013003161A1 (en) |
CO (1) | CO6940408A2 (en) |
IL (1) | IL229170A0 (en) |
MX (1) | MX2013012745A (en) |
RU (1) | RU2013150323A (en) |
SG (1) | SG194725A1 (en) |
TW (1) | TW201247240A (en) |
WO (1) | WO2012151237A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA115876C2 (en) | 2012-06-13 | 2018-01-10 | Івофем, Інк. | Compositions and methods for enhancing the efficacy of contraceptive microbicides |
JP2016519666A (en) * | 2013-03-15 | 2016-07-07 | イースタン バージニア メディカル スクール | Low glycerin formulation for HIV treatment and prevention |
WO2015070072A1 (en) * | 2013-11-07 | 2015-05-14 | Evofem, Inc. | Methods for manufacturing contraceptive microbicides with antiviral properties |
US11337989B2 (en) * | 2013-12-19 | 2022-05-24 | Evofem, Inc. | Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound |
CN104971045A (en) * | 2014-04-11 | 2015-10-14 | 上海宣泰医药科技有限公司 | Posaconazole medicine composition, preparation method and medicine preparation thereof |
BR112017002888A2 (en) | 2014-08-12 | 2017-12-05 | Nextgen Jane Inc | system and method for health monitoring in body fluid collected |
CN104434992B (en) * | 2014-12-21 | 2018-06-08 | 昆明赛诺制药股份有限公司 | A kind of American-cockroach-extract bioadhesive vaginal tablets and preparation method thereof |
CA2988082C (en) | 2015-06-01 | 2020-09-29 | Symbiomix Therapeutics, Llc | Novel nitroimidazole formulations and uses thereof |
WO2017180909A1 (en) | 2016-04-13 | 2017-10-19 | Nextgen Jane, Inc. | Sample collection and preservation devices, systems and methods |
US11419835B2 (en) | 2016-10-04 | 2022-08-23 | Evofem, Inc. | Method of treatment and prevention of bacterial vaginosis |
CA3040422A1 (en) * | 2016-10-13 | 2018-04-19 | Catalent U.K. Swindon Zydis Limited | Lyophilized pharmaceutical compositions for vaginal delivery |
MX2021004553A (en) * | 2018-10-23 | 2021-07-16 | Eastern Virginia Medical School | Pharmaceutical compositions and methods of making on demand solid dosage formulations. |
MX2021007525A (en) * | 2018-12-21 | 2021-09-21 | Univ Liverpool | Nrti therapies. |
WO2020213983A1 (en) * | 2019-04-19 | 2020-10-22 | 한양대학교 산학협력단 | Thermosensitive composition containing phosphatidic acid and use thereof |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
US20050276836A1 (en) | 1997-06-11 | 2005-12-15 | Michelle Wilson | Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents |
US20030118645A1 (en) * | 1998-04-29 | 2003-06-26 | Pather S. Indiran | Pharmaceutical compositions for rectal and vaginal administration |
US6159491A (en) * | 1999-02-12 | 2000-12-12 | Biovector Technologies, Inc. | Prolonged release bioadhesive vaginal gel dosage form |
GB0205253D0 (en) * | 2002-03-06 | 2002-04-17 | Univ Gent | Immediate release pharmaceutical granule compositions and a continuous process for making them |
US6899890B2 (en) | 2002-03-20 | 2005-05-31 | Kv Pharmaceutical Company | Bioadhesive drug delivery system |
US20040228932A1 (en) * | 2003-05-12 | 2004-11-18 | Pilgaonkar Pratibha S. | Pharmaceutical excipient |
US8545881B2 (en) | 2004-04-19 | 2013-10-01 | Eurand Pharmaceuticals, Ltd. | Orally disintegrating tablets and methods of manufacture |
JP2006022039A (en) * | 2004-07-08 | 2006-01-26 | Towa Yakuhin Kk | Simvastatin solid preparation having high stability |
UA93354C2 (en) | 2004-07-09 | 2011-02-10 | Гилиад Сайенсиз, Инк. | Topical antiviral formulations |
CN1257715C (en) * | 2004-08-02 | 2006-05-31 | 程月发 | Clindamycin metronidazole vagina effervescent tablet and its preparing method and use |
WO2006082596A2 (en) * | 2005-01-19 | 2006-08-10 | Kamalinder Kaur Singh | Neem oil contraceptive formulations |
US8158152B2 (en) * | 2005-11-18 | 2012-04-17 | Scidose Llc | Lyophilization process and products obtained thereby |
US8252329B2 (en) * | 2007-01-05 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
CN1970079A (en) * | 2006-12-08 | 2007-05-30 | 陕西沃普森制药有限公司 | Vagina effervescence tablet of recombinant human interferon alpha-2a and preparation process thereof |
CN101547898B (en) * | 2006-12-10 | 2014-09-24 | 于崇曦 | Transdermal delivery systems of beta-lactam antibiotics |
CA2687310A1 (en) * | 2007-05-24 | 2008-12-04 | New York Blood Center Inc. | Rapidly dispersible vaginal tablet that provides a bioadhesive gel |
CL2008003827A1 (en) * | 2007-12-21 | 2009-07-24 | Aptalis Pharmatech Inc | Composition for orally disintegrating tablets comprising at least one drug (temazepam), 0.5-3% of a binder polymer for odt, a sugar alcohol and / or saccharide, and a disintegrant; method to prepare it; Useful to treat a disease or condition such as a sleep disorder in patients with dysphagia. |
CN101406463B (en) * | 2008-02-28 | 2012-04-25 | 陕西君碧莎制药有限公司 | Metronidazole, clotrimazole and chlorhexidime vaginal effervescent tablet and preparation method |
CN101283989A (en) * | 2008-02-28 | 2008-10-15 | 何文健 | Metronidazole vaginal tablet process and quality control method |
WO2010048389A2 (en) * | 2008-10-23 | 2010-04-29 | Henkel Corporation | Pharmaceutical pellets comprising modified starch and therapeutic applications therefor |
CN101780203B (en) * | 2010-03-16 | 2012-09-05 | 刘仁杰 | Lubrication effervescent agent for yin nourishing, nest warming, body deodorizing and youth keeping and preparation method thereof |
-
2012
- 2012-05-02 WO PCT/US2012/036055 patent/WO2012151237A1/en active Application Filing
- 2012-05-02 AR ARP120101551A patent/AR086249A1/en unknown
- 2012-05-02 CN CN201280026286.XA patent/CN103596556A/en active Pending
- 2012-05-02 CA CA2839790A patent/CA2839790A1/en not_active Abandoned
- 2012-05-02 EP EP12779335.4A patent/EP2704694A4/en not_active Withdrawn
- 2012-05-02 TW TW101115691A patent/TW201247240A/en unknown
- 2012-05-02 KR KR1020167025256A patent/KR20160112012A/en not_active Application Discontinuation
- 2012-05-02 MX MX2013012745A patent/MX2013012745A/en unknown
- 2012-05-02 RU RU2013150323/15A patent/RU2013150323A/en not_active Application Discontinuation
- 2012-05-02 JP JP2014509373A patent/JP6154803B2/en not_active Expired - Fee Related
- 2012-05-02 AP AP2013007268A patent/AP2013007268A0/en unknown
- 2012-05-02 KR KR1020137031788A patent/KR20140014264A/en active Search and Examination
- 2012-05-02 AU AU2012250862A patent/AU2012250862B2/en not_active Ceased
- 2012-05-02 SG SG2013080882A patent/SG194725A1/en unknown
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2013
- 2013-10-31 IL IL229170A patent/IL229170A0/en unknown
- 2013-11-04 CL CL2013003161A patent/CL2013003161A1/en unknown
- 2013-11-29 CO CO13281162A patent/CO6940408A2/en unknown
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CA2839790A1 (en) | 2012-11-08 |
CO6940408A2 (en) | 2014-05-09 |
NZ617376A (en) | 2016-03-31 |
WO2012151237A1 (en) | 2012-11-08 |
EP2704694A1 (en) | 2014-03-12 |
TW201247240A (en) | 2012-12-01 |
RU2013150323A (en) | 2015-06-10 |
AP2013007268A0 (en) | 2013-11-30 |
CN103596556A (en) | 2014-02-19 |
MX2013012745A (en) | 2014-12-05 |
KR20140014264A (en) | 2014-02-05 |
JP6154803B2 (en) | 2017-06-28 |
EP2704694A4 (en) | 2014-11-19 |
IL229170A0 (en) | 2013-12-31 |
AU2012250862A1 (en) | 2013-05-02 |
CL2013003161A1 (en) | 2014-08-01 |
SG194725A1 (en) | 2013-12-30 |
JP2014513124A (en) | 2014-05-29 |
KR20160112012A (en) | 2016-09-27 |
AU2012250862B2 (en) | 2015-07-09 |
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