AR030681A1 - PIRAZOLO COMPOUNDS [4,3-] PIRIMIDIN-7-ONAS, PHARMACEUTICAL COMPOSITION, VETERINARY FORMULATION, USE IN THE MANUFACTURE OF MEDICINAL PRODUCT, PROCEDURE FOR THE PREPARATION OF SUCH COMPOUNDS, INTERMEDIARY COMPOUNDS AND THEIR PREPARATION - Google Patents
PIRAZOLO COMPOUNDS [4,3-] PIRIMIDIN-7-ONAS, PHARMACEUTICAL COMPOSITION, VETERINARY FORMULATION, USE IN THE MANUFACTURE OF MEDICINAL PRODUCT, PROCEDURE FOR THE PREPARATION OF SUCH COMPOUNDS, INTERMEDIARY COMPOUNDS AND THEIR PREPARATIONInfo
- Publication number
- AR030681A1 AR030681A1 ARP000105333A ARP000105333A AR030681A1 AR 030681 A1 AR030681 A1 AR 030681A1 AR P000105333 A ARP000105333 A AR P000105333A AR P000105333 A ARP000105333 A AR P000105333A AR 030681 A1 AR030681 A1 AR 030681A1
- Authority
- AR
- Argentina
- Prior art keywords
- compounds
- preparation
- pirazolo
- pirimidin
- onas
- Prior art date
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Los compuestos de formula (1) en la que R1, R2, R4 y R13 son como se ha definido en la memoria, una sal o polimorfo farmacéutica o veterinariamente aceptable de los mismos, o un solvato o profármaco farmacéutica o veterinariamente aceptable de los mismos: son inhibidores potentes y selectivos de la guanosina 3', 5'-monofosfato cíclico fosfodiesterasa de tipo 5 ( GPMc PDE5) y tienen utilidad en el tratamiento de, entre otras afecciones, la disfuncion eréctil masculina (MED) y la disfuncion sexual femenina (FSD).The compounds of formula (1) in which R1, R2, R4 and R13 are as defined herein, a pharmaceutically or veterinarily acceptable salt or polymorph thereof, or a pharmaceutically or veterinarily acceptable solvate or prodrug thereof. : they are potent and selective inhibitors of guanosine 3 ', 5'-cyclic phosphodiesterase type 5 (GPMc PDE5) and have utility in the treatment of, among other conditions, male erectile dysfunction (MED) and female sexual dysfunction ( FSD).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92406399A | 1999-10-11 | 1999-10-11 | |
| US1865600A | 2000-07-28 | 2000-07-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR030681A1 true AR030681A1 (en) | 2003-09-03 |
Family
ID=37515917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000105333A AR030681A1 (en) | 1999-10-11 | 2000-10-10 | PIRAZOLO COMPOUNDS [4,3-] PIRIMIDIN-7-ONAS, PHARMACEUTICAL COMPOSITION, VETERINARY FORMULATION, USE IN THE MANUFACTURE OF MEDICINAL PRODUCT, PROCEDURE FOR THE PREPARATION OF SUCH COMPOUNDS, INTERMEDIARY COMPOUNDS AND THEIR PREPARATION |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR030681A1 (en) |
-
2000
- 2000-10-10 AR ARP000105333A patent/AR030681A1/en active IP Right Grant
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |