US8158348B2

Chamsart et al., 2007

Alkaline‐cell lysis through in‐line static mixer reactor for the production of plasmid DNA for gene therapy

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Document ID: 10168377733163327283
Author: Chamsart S; Karnjanasorn T
Publication year: 2007
Publication venue: Biotechnology and bioengineering

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A state‐of‐the‐art in‐line static mixer reactor (ISMR) was invented to lyse E. coli cells and neutralize the cell lysate continuously and efficiently for the extraction of plasmid DNA. It comprised two connected static dynamic mixers, each 0.01 m in diameter and 0.9 m in …

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230000009089 cytolysis 0 title abstract description 132

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