ZA989424B - Purification of molecules. - Google Patents
Purification of molecules.Info
- Publication number
- ZA989424B ZA989424B ZA9809424A ZA989424A ZA989424B ZA 989424 B ZA989424 B ZA 989424B ZA 9809424 A ZA9809424 A ZA 9809424A ZA 989424 A ZA989424 A ZA 989424A ZA 989424 B ZA989424 B ZA 989424B
- Authority
- ZA
- South Africa
- Prior art keywords
- contaminants
- molecules
- molecule
- purification
- column
- Prior art date
Links
- 238000000746 purification Methods 0.000 title 1
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 abstract 2
- 239000000356 contaminant Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 229940051250 hexylene glycol Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- -1 peptidyl compound Chemical class 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000004366 reverse phase liquid chromatography Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95776097A | 1997-10-24 | 1997-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA989424B true ZA989424B (en) | 2000-04-17 |
Family
ID=25500093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9809424A ZA989424B (en) | 1997-10-24 | 1998-10-15 | Purification of molecules. |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1025126B1 (ja) |
| JP (1) | JP4239131B2 (ja) |
| AT (1) | ATE237636T1 (ja) |
| AU (1) | AU740665B2 (ja) |
| CA (1) | CA2306447C (ja) |
| DE (1) | DE69813599T2 (ja) |
| DK (1) | DK1025126T3 (ja) |
| ES (1) | ES2195409T3 (ja) |
| HK (1) | HK1031387A1 (ja) |
| IL (1) | IL135087A (ja) |
| PT (1) | PT1025126E (ja) |
| WO (1) | WO1999021889A1 (ja) |
| ZA (1) | ZA989424B (ja) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE382057T1 (de) | 2001-06-28 | 2008-01-15 | Novo Nordisk As | Stabile formulierung von modifiziertem glp-1 |
| JP4936884B2 (ja) | 2003-06-03 | 2012-05-23 | ノボ・ノルデイスク・エー／エス | 安定化された薬学的ペプチド組成物 |
| PL1633391T3 (pl) | 2003-06-03 | 2012-03-30 | Novo Nordisk As | Stabilizowane farmaceutycznie kompozycje peptydowe |
| HUE038395T2 (hu) | 2003-11-20 | 2018-10-29 | Novo Nordisk As | Propilén-glikol tartalmú peptidkészítmények, amelyek elõállításra és injekciós eszközökben történõ alkalmazásra optimálisak |
| JP4965446B2 (ja) * | 2004-08-31 | 2012-07-04 | ノヴォ ノルディスク アー／エス | ペプチド、ポリペプチド及びタンパク質の安定化のためのトリス（ヒドロキシメチル）アミノメタンの使用 |
| AU2005303777B2 (en) | 2004-11-12 | 2010-12-16 | Novo Nordisk A/S | Stable formulations of insulinotropic peptides |
| EP1966232A1 (en) | 2005-12-23 | 2008-09-10 | Novo Nordisk A/S | Purification of proteins using preparative reverse phase chromatography (rpc) |
| AU2011343813B2 (en) | 2010-12-15 | 2015-05-21 | Takeda Pharmaceutical Company Limited | Eluate collection using conductivity gradient |
| TWI762706B (zh) | 2017-08-24 | 2022-05-01 | 丹麥商諾佛 儂迪克股份有限公司 | Glp-1組成物及其用途 |
| BR112022013795A2 (pt) | 2020-02-18 | 2022-09-13 | Novo Nordisk As | Composição farmacêutica líquida, e, kit |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743680A (en) * | 1985-02-01 | 1988-05-10 | New York University | Method for purifying antihemophilic factor |
| US5446024A (en) * | 1993-12-17 | 1995-08-29 | Genentech, Inc. | Purification of insulin-like growth factor |
-
1998
- 1998-10-08 AU AU10725/99A patent/AU740665B2/en not_active Expired
- 1998-10-08 IL IL13508798A patent/IL135087A/xx not_active IP Right Cessation
- 1998-10-08 EP EP98953320A patent/EP1025126B1/en not_active Expired - Lifetime
- 1998-10-08 DK DK98953320T patent/DK1025126T3/da active
- 1998-10-08 AT AT98953320T patent/ATE237636T1/de active
- 1998-10-08 DE DE69813599T patent/DE69813599T2/de not_active Expired - Lifetime
- 1998-10-08 ES ES98953320T patent/ES2195409T3/es not_active Expired - Lifetime
- 1998-10-08 JP JP2000517996A patent/JP4239131B2/ja not_active Expired - Lifetime
- 1998-10-08 PT PT98953320T patent/PT1025126E/pt unknown
- 1998-10-08 WO PCT/US1998/021238 patent/WO1999021889A1/en active IP Right Grant
- 1998-10-08 CA CA002306447A patent/CA2306447C/en not_active Expired - Lifetime
- 1998-10-15 ZA ZA9809424A patent/ZA989424B/xx unknown
-
2001
- 2001-02-09 HK HK01100970A patent/HK1031387A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999021889A1 (en) | 1999-05-06 |
| ATE237636T1 (de) | 2003-05-15 |
| PT1025126E (pt) | 2003-09-30 |
| HK1031387A1 (en) | 2001-06-15 |
| CA2306447C (en) | 2009-04-07 |
| IL135087A (en) | 2005-05-17 |
| EP1025126A1 (en) | 2000-08-09 |
| DE69813599T2 (de) | 2004-04-08 |
| EP1025126B1 (en) | 2003-04-16 |
| DK1025126T3 (da) | 2003-08-04 |
| DE69813599D1 (de) | 2003-05-22 |
| ES2195409T3 (es) | 2003-12-01 |
| JP2001521044A (ja) | 2001-11-06 |
| AU1072599A (en) | 1999-05-17 |
| CA2306447A1 (en) | 1999-05-06 |
| AU740665B2 (en) | 2001-11-08 |
| JP4239131B2 (ja) | 2009-03-18 |
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