ZA9811799B - Solid galenic form of the controlled release tablet type for the instant and then prolonged release of one or more active substances - Google Patents

Solid galenic form of the controlled release tablet type for the instant and then prolonged release of one or more active substances

Info

Publication number
ZA9811799B
ZA9811799B ZA9811799A ZA9811799A ZA9811799B ZA 9811799 B ZA9811799 B ZA 9811799B ZA 9811799 A ZA9811799 A ZA 9811799A ZA 9811799 A ZA9811799 A ZA 9811799A ZA 9811799 B ZA9811799 B ZA 9811799B
Authority
ZA
South Africa
Prior art keywords
instant
active substances
tablet type
galenic form
controlled release
Prior art date
Application number
ZA9811799A
Other languages
English (en)
Inventor
Olivier Saslawski
Laurence Orlando
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA9811799B publication Critical patent/ZA9811799B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
ZA9811799A 1997-12-23 1998-12-22 Solid galenic form of the controlled release tablet type for the instant and then prolonged release of one or more active substances ZA9811799B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9716402A FR2772615B1 (fr) 1997-12-23 1997-12-23 Comprime multicouche pour la liberation instantanee puis prolongee de substances actives

Publications (1)

Publication Number Publication Date
ZA9811799B true ZA9811799B (en) 1999-06-22

Family

ID=9515042

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9811799A ZA9811799B (en) 1997-12-23 1998-12-22 Solid galenic form of the controlled release tablet type for the instant and then prolonged release of one or more active substances

Country Status (24)

Country Link
US (1) US6372255B1 (de)
EP (1) EP1041972B1 (de)
JP (1) JP4451563B2 (de)
KR (1) KR100574207B1 (de)
CN (1) CN1163220C (de)
AR (1) AR017897A1 (de)
AT (1) ATE223207T1 (de)
AU (1) AU743195B2 (de)
BR (1) BR9814345A (de)
CA (1) CA2316277C (de)
CZ (1) CZ291884B6 (de)
DE (1) DE69807747T2 (de)
DK (1) DK1041972T3 (de)
ES (1) ES2182397T3 (de)
FR (1) FR2772615B1 (de)
HU (1) HU226069B1 (de)
ID (1) ID26313A (de)
NO (1) NO20003289L (de)
PT (1) PT1041972E (de)
RU (1) RU2212885C2 (de)
SK (1) SK283236B6 (de)
UA (1) UA55503C2 (de)
WO (1) WO1999033448A1 (de)
ZA (1) ZA9811799B (de)

Families Citing this family (158)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9407386D0 (en) 1994-04-14 1994-06-08 Smithkline Beecham Plc Pharmaceutical formulation
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
US8022095B2 (en) * 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
DE19821625C1 (de) * 1998-05-15 2000-01-05 Merck Patent Gmbh Pharmazeutische Zubereitung
EP1005863A1 (de) * 1998-12-04 2000-06-07 Synthelabo Dosisformen mit gesteuerter Wirkstofffreigabe enthaltend ein kurzer wirkung Hypnotikum oder einem Salz davon
US6294199B1 (en) * 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US7250176B1 (en) * 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
EP1064937A1 (de) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmazeutische Zusammensetzungen mit kontrollierten Freigabe enthaltend ein Hypnotikum mit kurzer Wirkung oder deren Salze
AU6558900A (en) * 1999-08-20 2001-03-19 Ferrosan A/S A pharmaceutical delivery system for vitamin c and vitamin and use of a combination of vitamin C and E for preventing or treating conditions involving oxidative stress
AU783656B2 (en) * 1999-09-02 2005-11-24 Nostrum Pharmaceuticals, Inc. Controlled release oral dosage suitable for oral administration
RU2238087C2 (ru) * 1999-09-28 2004-10-20 Панацея Биотек Лимитед Композиции контролируемого высвобождения, содержащие нимесулид
EP1138330A1 (de) * 1999-12-23 2001-10-04 Warner-Lambert Company Kombinationsarzneimittel enthaltend Trimebutin und ein Opiatanalgetikum
BR0007360A (pt) * 1999-12-23 2001-08-14 Johnson & Johnson Composição de liberação controlada
AU767812B2 (en) * 2000-02-04 2003-11-27 Depomed, Inc. Shell-and-core dosage form approaching zero-order drug release
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US20070141107A1 (en) * 2000-03-15 2007-06-21 Orbusneich Medical, Inc. Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device
US6372252B1 (en) * 2000-04-28 2002-04-16 Adams Laboratories, Inc. Guaifenesin sustained release formulation and tablets
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
WO2002030392A2 (en) 2000-10-12 2002-04-18 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
ES2220789T3 (es) * 2000-10-30 2004-12-16 Lupin Limited Composicion de cefuroxima axetilo de liberacion lenta que se desintegra rapidamente.
KR100778835B1 (ko) * 2000-12-28 2007-11-22 엘지.필립스 엘시디 주식회사 액정표시장치의 제조방법
KR100685945B1 (ko) 2000-12-29 2007-02-23 엘지.필립스 엘시디 주식회사 액정표시장치 및 그 제조방법
WO2002064093A2 (en) * 2001-02-15 2002-08-22 King Pharmaceuticals, Inc. Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
CA2343949A1 (en) * 2001-04-12 2002-10-12 Bernard Charles Sherman Benazepril hydrochloride tablet formulations
SE0101379D0 (sv) 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
US20030035839A1 (en) * 2001-05-15 2003-02-20 Peirce Management, Llc Pharmaceutical composition for both intraoral and oral administration
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
GB0114069D0 (en) * 2001-06-08 2001-08-01 Smithkline Beecham Plc Composition
US20030198671A1 (en) * 2001-08-10 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique plasma AUC properties
US20030198667A1 (en) * 2001-08-10 2003-10-23 Franz Andrew G. Methods of producing dispersible pharmaceutical compositions
US20030190349A1 (en) * 2001-08-10 2003-10-09 Franz G. Andrew Methods of stabilizing pharmaceutical compositions
US20030180353A1 (en) * 2001-08-10 2003-09-25 Franz G. Andrew Stabilized pharmaceutical compositions
US20030199586A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Unique levothyroxine aqueous materials
US20030195253A1 (en) * 2001-08-14 2003-10-16 Franz G. Andrew Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US20030198672A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique triidothyronine plasma AUC properties
US20030199587A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique Cmax properties
US20030203967A1 (en) * 2001-08-14 2003-10-30 Franz G. Andrew Levothyroxine compositions having unique Tmax properties
US20030175337A1 (en) * 2001-10-29 2003-09-18 Franz G. Andrew Levothyroxine compositions having unique triiodothyronine Tmax properties
US20030099699A1 (en) * 2001-11-13 2003-05-29 Hanshew Dwight D. Storage stable thyroxine active drug formulations and methods for their production
US6645526B2 (en) * 2001-11-13 2003-11-11 Mylan Pharmaceuticals, Inc. Storage stable thyroxine active drug formulations and methods for their production
US6863901B2 (en) 2001-11-30 2005-03-08 Collegium Pharmaceutical, Inc. Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration
US6827946B2 (en) 2001-12-05 2004-12-07 Collegium Pharmaceutical, Inc. Compositions containing both sedative and non-sedative antihistamines
US6682759B2 (en) 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
EP1515701B1 (de) 2002-06-17 2014-09-17 Inventia Healthcare Private Limited Verfahren zur herstellung von mehrschichtigen tabletten die thiazolidinedione und biguanide enthalten
AR040682A1 (es) 2002-07-25 2005-04-13 Pharmacia Corp Forma de dosificacion una vez al dia de pramipexol
AR040588A1 (es) * 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
US20040116532A1 (en) * 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
AU2003272504A1 (en) * 2002-09-20 2004-04-08 Andrx Labs Llc Multistage formulation containing a biguanide and thiazolidindione derivatives
SE0203065D0 (sv) * 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
TWI319713B (en) * 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
US8487002B2 (en) * 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
MXPA02010828A (es) * 2002-11-04 2004-07-16 Leopoldo Espinosa Abdala Composicion farmaceutica en capsulas que comprende un antiinflamatorio no esteroideo y un analgesico opiaceo para el manejo del dolor.
US20040115265A1 (en) * 2002-12-11 2004-06-17 Loutfy Benkerrour Multilayered tablet containing pravastatin and aspirin and method
US20040253311A1 (en) * 2002-12-18 2004-12-16 Roger Berlin Multi-layer tablet comprising non-steroidal anti-inflammatory drugs, decongestants and non-sedating antihist amines
AU2003303631B2 (en) * 2002-12-26 2008-05-29 Nuvo Pharmaceuticals (Ireland) Designated Activity Company Multilayer Dosage Forms Containing NSAIDs and Triptans
TWI355276B (en) * 2003-01-14 2012-01-01 Akira Tsuji Gastrointestinal absorption enhancer mediated by p
WO2004064815A1 (en) * 2003-01-21 2004-08-05 Smartrix Technologies Inc. Oral dosage formulation
WO2004071497A1 (en) * 2003-02-11 2004-08-26 Alza Corporation Methods and dosage forms with modified layer geometry
FR2851734B1 (fr) * 2003-02-28 2006-06-09 Galenix Innovations Procede pour la fabrication d'une composition pharmaceutique sous la forme de comprimes contenant un fibrate et comprimes obtenus selon le procede
US20040224017A1 (en) * 2003-03-14 2004-11-11 Nirmal Mulye Process for preparing sustained release tablets
US20040192781A1 (en) * 2003-03-31 2004-09-30 Haley Eugene T. Method of administration for metoclopramide and pharmaceutical formulation therefor
DK2204168T3 (en) 2003-04-07 2015-04-07 Supernus Pharmaceuticals Inc Tetracycline for administration once a day
US20050013863A1 (en) 2003-07-18 2005-01-20 Depomed, Inc., A Corporation Of The State Of California Dual drug dosage forms with improved separation of drugs
US6863830B1 (en) * 2003-08-21 2005-03-08 Biolab Services, Inc. Dual layer tablet, method of making and use thereof
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
MXPA06003101A (es) * 2003-09-19 2006-06-20 Penwest Pharmaceuticals Co Formas de dosis cronoterapeuticas.
MXPA06003450A (es) 2003-09-26 2006-08-31 Johnson & Johnson Recubrimiento de farmaco que proporciona alta carga del farmaco y metodos para proporcionar el mismo.
JP5670609B2 (ja) * 2003-09-26 2015-02-18 アルザ・コーポレーシヨン 有効成分の制御送達のためのorosプッシュ−スティック
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
US20050084531A1 (en) * 2003-10-16 2005-04-21 Jatin Desai Tablet with aqueous-based sustained release coating
CA2552630A1 (en) * 2004-01-06 2005-07-21 Panacea Biotec Ltd. Non-disintegrating oral solid composition of high dose of water soluble drugs
US20050226929A1 (en) * 2004-04-12 2005-10-13 Jianbo Xie Controlled release opioid analgesic formulation
WO2005099672A1 (en) * 2004-04-13 2005-10-27 Ranbaxy Laboratories Limited A modified release pharmaceutical formulation comprising amoxicillin and clavulanate
PL1591109T3 (pl) * 2004-04-30 2008-11-28 Topotarget Germany Ag Preparat zawierający inhibitor deacetylazy histonów wykazujący dwufazowe uwalnianie”
FR2873113B1 (fr) * 2004-07-19 2007-06-15 Eurotab Sa Produit solide compacte bicouche de purification d'eau
US20060020007A1 (en) * 2004-07-26 2006-01-26 Roger Berlin Compositions containing policosanol and biotin and their pharmaceutical uses
NZ553561A (en) * 2004-08-13 2010-12-24 Boehringer Ingelheim Int Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
JP4997109B2 (ja) 2004-09-01 2012-08-08 ユーロ−セルティーク エス.エイ. 用量比例的な定常状態caveおよび定常状態auc、ならびに、用量比例よりも小さい単回投与cmaxを有するオピオイド投薬形態物
US20060280789A1 (en) * 2004-12-27 2006-12-14 Eisai Research Institute Sustained release formulations
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
US20090208579A1 (en) * 2004-12-27 2009-08-20 Eisai R & D Management Co., Ltd. Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same
EP1830886B1 (de) * 2004-12-27 2016-04-13 Eisai R&D Management Co., Ltd. Verfahren zur stabilisierung eines arzneimittels gegen demenz
EA200701591A1 (ru) * 2005-01-26 2008-02-28 Элан Фарма Интернэшнл Лимитед Композиции с контролируемым высвобождением, содержащие антипсихотическое средство
DE102005019458A1 (de) * 2005-04-25 2006-10-26 Grünenthal GmbH Darreichungsform mit verbesserter Freisetzung von Cefuroximaxetil
CA2604617C (en) * 2005-04-28 2014-06-17 Eisai R&D Management Co., Ltd. Composition containing anti-dementia drug
WO2007036809A2 (en) * 2005-05-24 2007-04-05 Flamel Technologies S.A. Novel acetylsalicylic acid formulations
US20070020333A1 (en) * 2005-07-20 2007-01-25 Chin-Chih Chiang Controlled release of hypnotic agents
GB0516604D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Rapidly dispersing/disintegrating compositions
BRPI0615860B8 (pt) * 2005-09-09 2021-05-25 Labopharm Barbados Ltd composição farmacêutica de liberação prolongada monolítica sólida
WO2007040511A1 (en) * 2005-09-28 2007-04-12 Teva Pharmaceutical Industries Ltd. Stable combinations of amlodipine besylate and benazepril hydrochloride
DE102005048293A1 (de) * 2005-10-08 2007-04-12 Sanofi-Aventis Deutschland Gmbh Retardformulierung für Pralnacasan
EP1948132B1 (de) * 2005-11-18 2009-08-05 Synhton B.V. Zolpidemtabletten
CA2635313C (en) * 2005-12-29 2013-12-31 Osmotica Corp. Triple combination release multi-layered tablet
CZ300698B6 (cs) * 2006-06-16 2009-07-22 Zentiva, A. S. Tableta s obsahem metforminu
FR2906801B1 (fr) * 2006-10-05 2008-12-12 Eurotab Sa Produit solide compacte bicouche de potabilisaton d'eau et procede de preparation.
RU2453307C2 (ru) * 2006-10-30 2012-06-20 Ханол Биофарма Ко.Лтд Комплексная фармацевтическая композиция с контролируемым высвобождением, содержащая блокаторы рецепторов ангиотензина-ii и ингибиторы гидроксиметилглутарил-кофермент а-редуктазы
US8394845B2 (en) 2006-10-30 2013-03-12 Hanall Biopharma Co., Ltd. Method of using combination preparation comprising angiotensin-II-receptor blocker and HMG-CoA reductase inhibitor
WO2008105920A1 (en) * 2007-02-28 2008-09-04 Collegium Pharmaceutical, Inc. Antihistamine combination
US20100098757A1 (en) * 2007-03-15 2010-04-22 Toyo Boseki Kabushiki Kaisha Process for production of buprenorphine pharmaceutical preparation to be applied to mouth mucosa
WO2008142627A2 (en) * 2007-05-17 2008-11-27 Ranbaxy Laboratories Limited Multilayered modified release formulation comprising amoxicillin and clavulanate
KR20100020459A (ko) 2007-06-08 2010-02-22 아드레넥스 파마슈티컬스, 아이엔씨. 지연 방출형 제제 및 아드레날린 조절부전의 치료방법
US20100172991A1 (en) * 2007-06-08 2010-07-08 Henry Joseph Horacek Extended Release Formulation and Methods of Treating Adrenergic Dysregulation
US8404275B2 (en) 2007-07-01 2013-03-26 Vitalis Llc Combination tablet with chewable outer layer
WO2009024858A1 (en) * 2007-08-22 2009-02-26 Aurobindo Pharma Limited Controlled release dosage form of galantamine
ES2541809T3 (es) * 2007-10-16 2015-07-24 Paladin Labs Inc. Composición bicapa para la liberación sostenida de acetaminofeno y tramadol
KR20100121463A (ko) * 2007-12-17 2010-11-17 라보팜 인코포레이트 오용 예방적 방출 제어형 제제
FR2927965B1 (fr) * 2008-02-22 2010-06-04 Valeo Materiaux De Friction Sa Procede de fabrication d'un materiau de friction et notamment d'une couronne de friction d'embrayage.
WO2009154810A2 (en) * 2008-02-25 2009-12-23 Dr. Reddy's Laboratories Ltd. Delivery systems for multiple active agents
WO2009118764A1 (en) * 2008-03-28 2009-10-01 Panacea Biotec Limited Pharmaceutical composition comprising diclofenac and paracetamol
JP2009256237A (ja) * 2008-04-16 2009-11-05 Daiichi Sankyo Healthcare Co Ltd 固形製剤
MX340249B (es) 2008-08-15 2016-07-01 Depomed Inc Composiciones farmacéuticas retentivas gástricas para tratamiento y prevención de transtornos del sistema nervioso central (cns).
CA2736547C (en) 2008-09-09 2016-11-01 Pozen Inc. Method for delivering a pharmaceutical composition to patient in need thereof
WO2010045656A2 (en) * 2008-10-17 2010-04-22 Nectid, Inc. Novel sglt2 inhibitor dosage forms
WO2010053337A2 (ko) * 2008-11-10 2010-05-14 (주)아모레퍼시픽 서방성 미립자 및 이의 제조방법
WO2010069050A1 (en) 2008-12-16 2010-06-24 Labopharm Inc. Misuse preventative, controlled release formulation
SI2389166T1 (sl) * 2009-01-23 2013-02-28 F. Hoffmann-La Roche Ag Farmacevtski sestavek, ki obsega aleglitazar
KR101050076B1 (ko) * 2009-02-04 2011-07-19 한국유나이티드제약 주식회사 제어 방출성 아세클로페낙을 함유하는 경구 제제의 조성물 및 그의 제조방법
WO2010138441A1 (en) * 2009-05-28 2010-12-02 Aptapharma, Inc. Multilayer oral tablets containing a non-steroidal anti-inflammatory drug and/or acetaminophen
EA021112B1 (ru) * 2009-06-25 2015-04-30 Поузен Инк. Способ лечения боли и/или воспаления у пациента, нуждающегося в аспириновой терапии
MX2011013467A (es) 2009-06-25 2012-02-13 Astrazeneca Ab Metodo para tratar un paciente que corre el riesgo de desarollar una ulcera asociada a antiinflamatorio no esteroide (aine).
JP5885668B2 (ja) 2009-12-02 2016-03-15 アダマス ファーマシューティカルズ, インコーポレイテッド アマンタジン組成物および使用方法
EP2521537A2 (de) 2010-01-04 2012-11-14 Wockhardt Limited Pharmazeutische zusammensetzung zur modifizierten freisetzung von wirkstoffen
EP2394644B1 (de) * 2010-05-04 2014-07-09 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Trimetazidin-Formulierung mit unterschiedlichen Freisetzungsprofilen
KR20140007247A (ko) 2010-06-22 2014-01-17 티더블유아이 파머수티컬스, 인코포레이티드 음식물 영향이 감소된 제어 방출 조성물
CN102727496A (zh) * 2011-04-12 2012-10-17 上海双健现代药物技术咨询有限公司 一种复方抗结核药口服固体制剂及其制备方法
CN107296798A (zh) 2011-10-28 2017-10-27 维塔利斯公司 抗发红组合物
WO2013101897A2 (en) 2011-12-28 2013-07-04 Pozen Inc. Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid
US20140377350A1 (en) * 2012-01-31 2014-12-25 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Bilayer tablet formulations of flurbiprofen and glucosamin
EP2817001A1 (de) * 2012-02-20 2014-12-31 Lupin Limited Doppelschichttablette aus dronedaron
EP2787971A4 (de) 2012-02-22 2015-04-29 Duchesnay Inc Formulierung aus doxylamin und pyridoxin und/oder metaboliten oder salzen davon
US20140072671A1 (en) * 2012-06-29 2014-03-13 Adam Auerbach Multi-component oral delivery systems and uses thereof
WO2014075155A1 (pt) * 2012-11-14 2014-05-22 Diffucap Chemobras Química E Farmacêutica Ltda Combinação farmacêutica contendo agente analgésico e agente antiespasmódico
ES2821528T3 (es) 2012-11-14 2021-04-26 Grace W R & Co Composiciones que contienen un material biológicamente activo y un óxido inorgánico no ordenado
RU2521572C1 (ru) * 2012-12-21 2014-06-27 Федеральное государственное бюджетное учреждение науки Институт химии растворов им. Г.А. Крестова Российской академии наук (ИХР РАН) Сокристаллическая форма фенбуфена
MX2015012613A (es) * 2013-03-12 2016-07-06 Biohit Oyj Composicion para administracion oral para enlazar aldheidos en el tracto gastrointestinal.
ES2674045T3 (es) 2013-04-29 2018-06-27 Clariant Healthcare Packaging (France) S.A.S. Tapa para un recipiente
US10154971B2 (en) 2013-06-17 2018-12-18 Adamas Pharma, Llc Methods of administering amantadine
US9452181B2 (en) 2013-07-22 2016-09-27 Duchesnay Inc. Composition for the management of nausea and vomiting
MX366760B (es) 2013-07-22 2019-07-23 Duchesnay Inc Composición para la gestión de las náuseas y los vómitos.
WO2015027303A1 (pt) * 2013-08-28 2015-03-05 Diffucap Chemobras Quimica E Farmaceutica Ltda Procedimento. de fabricação de combinação farmacêutica contendo agente analgésico e agente antiespasmódico e combinação farmacêutica
WO2015063669A1 (en) 2013-10-30 2015-05-07 Wockhardt Limited Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof
WO2016029290A1 (en) * 2014-08-29 2016-03-03 Duchesnay Inc. Plurimodal release formulation of doxylamine and pyridoxine and/or metabolites or salts thereof
US9526703B2 (en) 2014-08-29 2016-12-27 Duchesnay Inc. Plurimodal release formulation of doxylamine and pyridoxine and/or metabolites or salts thereof
US9132096B1 (en) 2014-09-12 2015-09-15 Alkermes Pharma Ireland Limited Abuse resistant pharmaceutical compositions
CA3018328A1 (en) * 2014-10-31 2016-04-30 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US10413403B2 (en) * 2015-07-14 2019-09-17 Boston Scientific Scimed, Inc. Prosthetic heart valve including self-reinforced composite leaflets
BR112018001313B1 (pt) * 2015-07-23 2023-05-02 Athena Pharmaceutiques Sas Composição de zolpidem e processo para preparar a mesma
CN117860718A (zh) 2017-08-24 2024-04-12 阿达玛斯药物有限责任公司 金刚烷胺组合物、其制备和使用方法
AU2018322756B2 (en) 2017-08-29 2023-10-19 Conrig Pharma Aps Composition comprising suplatast tosilate
KR20210079216A (ko) * 2019-12-19 2021-06-29 (주)셀트리온 시벤졸린 또는 이의 염을 포함하는 약학 제형
CN114432300B (zh) * 2022-02-16 2023-08-01 平顶山市第二人民医院 含有比索洛尔和依那普利的药物组合物及其工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5911563B2 (ja) * 1980-02-27 1984-03-16 日本原子力研究所 多層構造の徐放性複合体を製造する方法
IT1206166B (it) * 1984-07-26 1989-04-14 Sigma Tau Ind Farmaceuti Dispositivo per rilasciare una sostanza in un fluido di dissoluzione con cinetica di ordine zero e procedimento per la sua preparazione
US4752479A (en) * 1986-05-27 1988-06-21 Ciba-Geigy Corporaton Multi vitamin and mineral dietary supplement with controlled release bioavailable iron
FR2645152B1 (fr) * 1989-03-30 1991-05-31 Lipha 3h-pteridinones-4, procedes de preparation et medicaments les contenant
EP0951279A1 (de) * 1997-01-10 1999-10-27 Abbott Laboratories Tablette für kontrollierte wirkstoffabgabe

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FR2772615A1 (fr) 1999-06-25
DK1041972T3 (da) 2003-01-06
CZ291884B6 (cs) 2003-06-18
NO20003289D0 (no) 2000-06-22
CN1283110A (zh) 2001-02-07
PT1041972E (pt) 2003-01-31
FR2772615B1 (fr) 2002-06-14
JP2001527034A (ja) 2001-12-25
SK9322000A3 (en) 2001-04-09
HU226069B1 (en) 2008-04-28
KR20010033532A (ko) 2001-04-25
ES2182397T3 (es) 2003-03-01
AU743195B2 (en) 2002-01-24
UA55503C2 (uk) 2003-04-15
CA2316277A1 (en) 1999-07-08
AU2160699A (en) 1999-07-19
BR9814345A (pt) 2000-10-03
CN1163220C (zh) 2004-08-25
JP4451563B2 (ja) 2010-04-14
AR017897A1 (es) 2001-10-24
EP1041972A1 (de) 2000-10-11
ID26313A (id) 2000-12-14
ATE223207T1 (de) 2002-09-15
CA2316277C (en) 2008-07-08
DE69807747D1 (de) 2002-10-10
RU2212885C2 (ru) 2003-09-27
CZ20002332A3 (cs) 2000-10-11
DE69807747T2 (de) 2003-06-12
WO1999033448A1 (en) 1999-07-08
EP1041972B1 (de) 2002-09-04
HUP0100406A2 (hu) 2001-08-28
KR100574207B1 (ko) 2006-04-27
SK283236B6 (sk) 2003-04-01
NO20003289L (no) 2000-08-22
US6372255B1 (en) 2002-04-16

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