ZA97676B - Method for inducing death of neoplastic cells using piperazine derivatives. - Google Patents
Method for inducing death of neoplastic cells using piperazine derivatives.Info
- Publication number
- ZA97676B ZA97676B ZA9700676A ZA97676A ZA97676B ZA 97676 B ZA97676 B ZA 97676B ZA 9700676 A ZA9700676 A ZA 9700676A ZA 97676 A ZA97676 A ZA 97676A ZA 97676 B ZA97676 B ZA 97676B
- Authority
- ZA
- South Africa
- Prior art keywords
- neoplastic cells
- piperazine derivatives
- inducing death
- death
- inducing
- Prior art date
Links
- 230000001939 inductive effect Effects 0.000 title 1
- 210000005170 neoplastic cell Anatomy 0.000 title 1
- 150000004885 piperazines Chemical class 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/592,540 US5733911A (en) | 1996-01-26 | 1996-01-26 | Method for inducing death of neoplastic cells using piperazne derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA97676B true ZA97676B (en) | 1997-08-25 |
Family
ID=24371096
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9700676A ZA97676B (en) | 1996-01-26 | 1997-01-27 | Method for inducing death of neoplastic cells using piperazine derivatives. |
Country Status (14)
Country | Link |
---|---|
US (3) | US5733911A (zh) |
EP (1) | EP0877614B1 (zh) |
JP (1) | JP4117404B2 (zh) |
KR (1) | KR100468271B1 (zh) |
CN (1) | CN1220490C (zh) |
AR (1) | AR005569A1 (zh) |
AT (1) | ATE219676T1 (zh) |
AU (1) | AU731125B2 (zh) |
CA (1) | CA2242657A1 (zh) |
DE (1) | DE69713570T2 (zh) |
ID (1) | ID18975A (zh) |
TW (1) | TW475897B (zh) |
WO (1) | WO1997026881A1 (zh) |
ZA (1) | ZA97676B (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2184855T3 (es) * | 1995-03-31 | 2003-04-16 | Nippon Chemiphar Co | Derivados del acido epoxisuccinico. |
US5733911A (en) * | 1996-01-26 | 1998-03-31 | Hitachi Chemical Co., Ltd. | Method for inducing death of neoplastic cells using piperazne derivatives |
DK1022276T3 (da) * | 1997-09-04 | 2003-09-29 | Nippon Chemiphar Co | Epoxysuccinamidderivater |
EP1094063A1 (en) | 1999-10-18 | 2001-04-25 | Applied Research Systems ARS Holding N.V. | 9-(Piperazinylalkyl)carbazoles as Bax-modulators |
US6376514B1 (en) * | 2000-10-17 | 2002-04-23 | The Procter & Gamble Co. | Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof |
US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
DE60127705T2 (de) * | 2000-10-23 | 2007-12-27 | Arizona Biomedical Research Commission, Phoenix | Antitumor verbindungen basierend auf der regulierung von protein prenylation |
WO2003044535A1 (en) * | 2001-11-22 | 2003-05-30 | Mehmet Ozturk | Method, antigen and antibody for distinguishing viable and apoptotic cells |
KR20160099081A (ko) * | 2013-07-26 | 2016-08-19 | 업데이트 파마 인코포레이트 | 비산트렌의 치료 효과 개선용 조합 방법 |
PL407922A1 (pl) * | 2014-04-16 | 2015-10-26 | Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Odpowiedzialnością | Nowe bisfosfoniany i ich zastosowanie |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55115878A (en) * | 1979-02-27 | 1980-09-06 | Taisho Pharmaceut Co Ltd | Epoxysuccinic acid derivative |
JPS55153778A (en) * | 1979-05-17 | 1980-11-29 | Taisho Pharmaceut Co Ltd | Epoxysuccinylamino acid derivative |
US4474800A (en) * | 1980-05-13 | 1984-10-02 | Taisho Pharmaceutical Co., Ltd. | Epoxysuccinyl amino acid derivatives |
JPS57169478A (en) * | 1981-04-10 | 1982-10-19 | Nippon Chemiphar Co Ltd | Piperazine derivative |
JPS6276A (ja) * | 1985-03-26 | 1987-01-06 | Toyo Jozo Co Ltd | 酵素阻害性新規物質 |
JPH0832698B2 (ja) * | 1987-05-08 | 1996-03-29 | 日本ケミファ株式会社 | ピペラジン誘導体 |
KR940003297B1 (ko) * | 1989-12-27 | 1994-04-20 | 니혼다바고 상교오 가부시기가이샤 | 1,3,2-디옥사티오렌옥시드 유도체 |
WO1993006143A1 (fr) * | 1991-09-19 | 1993-04-01 | Cray Valley Sa | Resines de petrole thermiquement stables, leur procede de preparation et leur application a la formulation d'adhesifs thermofusibles |
JPH0641067A (ja) * | 1992-04-20 | 1994-02-15 | Kitasato Inst:The | 新規カルパイン阻害物質kp−1241及びその製造法 |
ATE171171T1 (de) * | 1992-12-25 | 1998-10-15 | Mitsubishi Chem Corp | Alpha-aminoketon derivate |
US5733911A (en) * | 1996-01-26 | 1998-03-31 | Hitachi Chemical Co., Ltd. | Method for inducing death of neoplastic cells using piperazne derivatives |
-
1996
- 1996-01-26 US US08/592,540 patent/US5733911A/en not_active Expired - Fee Related
-
1997
- 1997-01-24 AT AT97903981T patent/ATE219676T1/de active
- 1997-01-24 JP JP52706097A patent/JP4117404B2/ja not_active Expired - Fee Related
- 1997-01-24 DE DE69713570T patent/DE69713570T2/de not_active Expired - Fee Related
- 1997-01-24 KR KR10-1998-0705786A patent/KR100468271B1/ko not_active IP Right Cessation
- 1997-01-24 CA CA002242657A patent/CA2242657A1/en not_active Abandoned
- 1997-01-24 WO PCT/US1997/001231 patent/WO1997026881A1/en active IP Right Grant
- 1997-01-24 EP EP97903981A patent/EP0877614B1/en not_active Expired - Lifetime
- 1997-01-24 AU AU18402/97A patent/AU731125B2/en not_active Ceased
- 1997-01-24 CN CNB971926689A patent/CN1220490C/zh not_active Expired - Fee Related
- 1997-01-27 ID IDP970229A patent/ID18975A/id unknown
- 1997-01-27 ZA ZA9700676A patent/ZA97676B/xx unknown
- 1997-01-27 AR ARP970100324A patent/AR005569A1/es not_active Application Discontinuation
- 1997-03-14 TW TW086103221A patent/TW475897B/zh not_active IP Right Cessation
- 1997-12-10 US US08/987,816 patent/US5859013A/en not_active Expired - Fee Related
- 1997-12-10 US US08/988,056 patent/US6054437A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ID18975A (id) | 1998-05-28 |
JP4117404B2 (ja) | 2008-07-16 |
DE69713570D1 (de) | 2002-08-01 |
WO1997026881A1 (en) | 1997-07-31 |
US5859013A (en) | 1999-01-12 |
CN1220490C (zh) | 2005-09-28 |
US5733911A (en) | 1998-03-31 |
CA2242657A1 (en) | 1997-07-31 |
EP0877614B1 (en) | 2002-06-26 |
JP2000505792A (ja) | 2000-05-16 |
AR005569A1 (es) | 1999-06-23 |
CN1212623A (zh) | 1999-03-31 |
TW475897B (en) | 2002-02-11 |
KR19990082064A (ko) | 1999-11-15 |
ATE219676T1 (de) | 2002-07-15 |
DE69713570T2 (de) | 2003-01-23 |
KR100468271B1 (ko) | 2005-07-05 |
EP0877614A1 (en) | 1998-11-18 |
AU731125B2 (en) | 2001-03-22 |
AU1840297A (en) | 1997-08-20 |
US6054437A (en) | 2000-04-25 |
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