ZA9603229B - Triacetin as a penetration enhancer for transdermal delivery of a basic drug - Google Patents

Triacetin as a penetration enhancer for transdermal delivery of a basic drug

Info

Publication number
ZA9603229B
ZA9603229B ZA9603229A ZA9603229A ZA9603229B ZA 9603229 B ZA9603229 B ZA 9603229B ZA 9603229 A ZA9603229 A ZA 9603229A ZA 9603229 A ZA9603229 A ZA 9603229A ZA 9603229 B ZA9603229 B ZA 9603229B
Authority
ZA
South Africa
Prior art keywords
triacetin
transdermal delivery
penetration enhancer
basic drug
drug
Prior art date
Application number
ZA9603229A
Inventor
Danyi Quan
Ninad A Deshpanday
Srinivasan Venkateshwaran
Charles D Ebert
Original Assignee
Theratech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to US08/429,757 priority Critical patent/US5601839A/en
Application filed by Theratech Inc filed Critical Theratech Inc
Publication of ZA9603229B publication Critical patent/ZA9603229B/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23704623&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA9603229(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/946Penetrant or absorbent, increases or enhances penetration into subject treated
ZA9603229A 1995-04-26 1996-04-23 Triacetin as a penetration enhancer for transdermal delivery of a basic drug ZA9603229B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US08/429,757 US5601839A (en) 1995-04-26 1995-04-26 Triacetin as a penetration enhancer for transdermal delivery of a basic drug

Publications (1)

Publication Number Publication Date
ZA9603229B true ZA9603229B (en) 1997-01-28

Family

ID=23704623

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9603229A ZA9603229B (en) 1995-04-26 1996-04-23 Triacetin as a penetration enhancer for transdermal delivery of a basic drug

Country Status (19)

Country Link
US (2) US5601839A (en)
EP (1) EP0871420B1 (en)
JP (2) JP3228341B2 (en)
KR (1) KR100275593B1 (en)
CN (3) CN100374161C (en)
AR (1) AR001721A1 (en)
AT (1) AT205694T (en)
AU (1) AU696777B2 (en)
CA (1) CA2217888C (en)
DE (3) DE69615399T2 (en)
DK (1) DK0871420T3 (en)
ES (1) ES2163012T3 (en)
HK (1) HK1084320A1 (en)
MX (1) MX9707868A (en)
NL (1) NL300200I1 (en)
NZ (1) NZ306249A (en)
PT (1) PT871420E (en)
WO (1) WO1996033678A1 (en)
ZA (1) ZA9603229B (en)

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HK1084320A1 (en) 2008-07-04
NL300200I1 (en) 2005-09-01
US5601839A (en) 1997-02-11
DK0871420T3 (en) 2002-01-21
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CA2217888C (en) 2001-08-28
AU5446796A (en) 1996-11-18
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JP4511691B2 (en) 2010-07-28
CN100374161C (en) 2008-03-12
EP0871420A4 (en) 1998-11-11
DE69615399D1 (en) 2001-10-25
DE122005000013I1 (en) 2005-06-23
CN1714867A (en) 2006-01-04
AR001721A1 (en) 1997-11-26
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CN1182358A (en) 1998-05-20
EP0871420A1 (en) 1998-10-21
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AU696777B2 (en) 1998-09-17
US5834010A (en) 1998-11-10
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CN1143688C (en) 2004-03-31
KR100275593B1 (en) 2000-12-15
WO1996033678A1 (en) 1996-10-31
PT871420E (en) 2002-03-28
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CN1507918A (en) 2004-06-30
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AT205694T (en) 2001-10-15
EP0871420B1 (en) 2001-09-19

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