ZA959434B - Adhesion receptor antagonists - Google Patents
Adhesion receptor antagonistsInfo
- Publication number
- ZA959434B ZA959434B ZA959434A ZA959434A ZA959434B ZA 959434 B ZA959434 B ZA 959434B ZA 959434 A ZA959434 A ZA 959434A ZA 959434 A ZA959434 A ZA 959434A ZA 959434 B ZA959434 B ZA 959434B
- Authority
- ZA
- South Africa
- Prior art keywords
- receptor antagonists
- adhesion receptor
- adhesion
- antagonists
- receptor
- Prior art date
Links
- 102000019997 adhesion receptor Human genes 0.000 title 1
- 108010013985 adhesion receptor Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4439846A DE4439846A1 (de) | 1994-11-08 | 1994-11-08 | Adhäsionsrezeptor-Antagonisten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA959434B true ZA959434B (en) | 1996-05-15 |
Family
ID=6532768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA959434A ZA959434B (en) | 1994-11-08 | 1995-11-07 | Adhesion receptor antagonists |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5776937A (fr) |
| EP (1) | EP0711770A1 (fr) |
| JP (1) | JPH08208629A (fr) |
| KR (1) | KR100384978B1 (fr) |
| CN (1) | CN1069640C (fr) |
| AR (1) | AR002245A1 (fr) |
| AU (1) | AU704184B2 (fr) |
| BR (1) | BR9505109A (fr) |
| CA (1) | CA2162223A1 (fr) |
| CO (1) | CO4520229A1 (fr) |
| CZ (1) | CZ291049B6 (fr) |
| DE (1) | DE4439846A1 (fr) |
| FI (1) | FI955351A (fr) |
| HU (1) | HU217085B (fr) |
| NO (1) | NO306113B1 (fr) |
| PL (1) | PL183595B1 (fr) |
| RU (1) | RU2155762C2 (fr) |
| SK (1) | SK281815B6 (fr) |
| TR (1) | TR199501389A2 (fr) |
| TW (1) | TW316903B (fr) |
| UA (1) | UA41928C2 (fr) |
| ZA (1) | ZA959434B (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0710657B1 (fr) * | 1994-11-02 | 1998-08-26 | MERCK PATENT GmbH | Antagonistes des récepteurs d'adhésion |
| US6046331A (en) * | 1998-12-17 | 2000-04-04 | Synaptic Pharmaceutical Corporation | Imidazolones and their use in treating benign prostatic hyperplasia and other disorders |
| JP2002533387A (ja) | 1998-12-23 | 2002-10-08 | ジー．ディー．サール ＆ カンパニー | 腫瘍治療の複合療法としてインテグリン拮抗物質と一つ以上の抗腫瘍剤を使用する方法 |
| JP2002535680A (ja) | 1999-01-27 | 2002-10-22 | ファルマシア・アンド・アップジョン・カンパニー | 延長因子ｐ活性モジュレーターのアッセイ方法 |
| AU2003275480A1 (en) * | 2002-10-07 | 2004-05-04 | Smithkline Beecham Corporation | Compounds |
| CN102796091A (zh) * | 2011-05-24 | 2012-11-28 | 北大方正集团有限公司 | 取代的噁唑烷酮化合物及其制备方法和应用 |
| SG11201500585XA (en) * | 2012-10-29 | 2015-04-29 | Hoffmann La Roche | 3,4-disubstituted oxazolidinone derivatives and their use as inhibitors of the calcium activated potassium channel |
| CN104230915B (zh) * | 2014-08-29 | 2016-08-17 | 南京大学 | 含噻唑烷二酮的苯基哌嗪衍生物及其制备方法与用途 |
| ES2919779T3 (es) | 2017-06-20 | 2022-07-28 | Imbria Pharmaceuticals Inc | Derivado de 1-[(2,3,4-trimetoxifenil)metil]-piperazina, composiciones del mismo y métodos para aumentar la eficiencia del metabolismo cardíaco |
| US11530184B2 (en) | 2020-06-30 | 2022-12-20 | Imbria Pharmaceuticals, Inc. | Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11780811B2 (en) | 2020-06-30 | 2023-10-10 | Imbria Pharmaceuticals, Inc. | Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11883396B2 (en) | 2021-05-03 | 2024-01-30 | Imbria Pharmaceuticals, Inc. | Methods of treating kidney conditions using modified forms of trimetazidine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3723797A1 (de) * | 1987-07-18 | 1989-01-26 | Merck Patent Gmbh | Oxazolidinone |
| US5053393A (en) * | 1988-07-20 | 1991-10-01 | Monsanto Company | Novel platelet-aggregation inhibitor |
| US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
| DE4005371A1 (de) * | 1990-02-21 | 1991-08-22 | Merck Patent Gmbh | Oxazolidinone |
| DE4017211A1 (de) * | 1990-05-29 | 1991-12-05 | Merck Patent Gmbh | Oxazolidinone |
| DE4405633A1 (de) * | 1993-05-01 | 1994-11-03 | Merck Patent Gmbh | Adhäsionsrezeptor-Antagonisten |
| DE4332384A1 (de) * | 1993-09-23 | 1995-03-30 | Merck Patent Gmbh | Adhäsionsrezeptor-Antagonisten III |
-
1994
- 1994-11-08 DE DE4439846A patent/DE4439846A1/de not_active Withdrawn
-
1995
- 1995-10-26 EP EP95116889A patent/EP0711770A1/fr not_active Withdrawn
- 1995-11-01 UA UA95114761A patent/UA41928C2/uk unknown
- 1995-11-02 AU AU36618/95A patent/AU704184B2/en not_active Ceased
- 1995-11-02 SK SK1368-95A patent/SK281815B6/sk unknown
- 1995-11-06 CZ CZ19952888A patent/CZ291049B6/cs not_active IP Right Cessation
- 1995-11-06 TW TW084111748A patent/TW316903B/zh active
- 1995-11-06 CA CA002162223A patent/CA2162223A1/fr not_active Abandoned
- 1995-11-07 NO NO954458A patent/NO306113B1/no not_active IP Right Cessation
- 1995-11-07 PL PL95311257A patent/PL183595B1/pl not_active IP Right Cessation
- 1995-11-07 CN CN95118753A patent/CN1069640C/zh not_active Expired - Fee Related
- 1995-11-07 BR BR9505109A patent/BR9505109A/pt not_active IP Right Cessation
- 1995-11-07 US US08/551,743 patent/US5776937A/en not_active Expired - Fee Related
- 1995-11-07 HU HU9503191A patent/HU217085B/hu not_active IP Right Cessation
- 1995-11-07 FI FI955351A patent/FI955351A/fi not_active IP Right Cessation
- 1995-11-07 KR KR1019950040017A patent/KR100384978B1/ko not_active IP Right Cessation
- 1995-11-07 ZA ZA959434A patent/ZA959434B/xx unknown
- 1995-11-08 RU RU95119427/04A patent/RU2155762C2/ru not_active IP Right Cessation
- 1995-11-08 CO CO95052761A patent/CO4520229A1/es unknown
- 1995-11-08 TR TR95/01389A patent/TR199501389A2/xx unknown
- 1995-11-08 AR ARP950100091A patent/AR002245A1/es unknown
- 1995-11-08 JP JP7313684A patent/JPH08208629A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CZ288895A3 (en) | 1996-06-12 |
| TR199501389A2 (tr) | 1996-07-21 |
| FI955351A0 (fi) | 1995-11-07 |
| KR100384978B1 (ko) | 2003-09-02 |
| SK281815B6 (sk) | 2001-08-06 |
| JPH08208629A (ja) | 1996-08-13 |
| HU217085B (hu) | 1999-11-29 |
| UA41928C2 (uk) | 2001-10-15 |
| NO306113B1 (no) | 1999-09-20 |
| CA2162223A1 (fr) | 1996-05-09 |
| EP0711770A1 (fr) | 1996-05-15 |
| HUT76052A (en) | 1997-06-30 |
| NO954458D0 (no) | 1995-11-07 |
| CZ291049B6 (cs) | 2002-12-11 |
| US5776937A (en) | 1998-07-07 |
| KR960017663A (ko) | 1996-06-17 |
| PL183595B1 (pl) | 2002-06-28 |
| DE4439846A1 (de) | 1996-05-09 |
| RU2155762C2 (ru) | 2000-09-10 |
| SK136895A3 (en) | 1996-06-05 |
| AU704184B2 (en) | 1999-04-15 |
| TW316903B (fr) | 1997-10-01 |
| CN1069640C (zh) | 2001-08-15 |
| BR9505109A (pt) | 1997-09-09 |
| CN1132201A (zh) | 1996-10-02 |
| AU3661895A (en) | 1996-05-23 |
| HU9503191D0 (en) | 1996-01-29 |
| CO4520229A1 (es) | 1997-10-15 |
| PL311257A1 (en) | 1996-05-13 |
| AR002245A1 (es) | 1998-03-11 |
| NO954458L (no) | 1996-05-09 |
| FI955351A (fi) | 1996-05-09 |
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