ZA943896B - Pharmaceutical agents for treatment of emesis - Google Patents

Pharmaceutical agents for treatment of emesis

Info

Publication number
ZA943896B
ZA943896B ZA943896A ZA943896A ZA943896B ZA 943896 B ZA943896 B ZA 943896B ZA 943896 A ZA943896 A ZA 943896A ZA 943896 A ZA943896 A ZA 943896A ZA 943896 B ZA943896 B ZA 943896B
Authority
ZA
South Africa
Prior art keywords
emesis
treatment
pharmaceutical agents
derivatives
mammals
Prior art date
Application number
ZA943896A
Other languages
English (en)
Inventor
Manoj C Desai
John A Lowe Iii
John W Watson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA943896B publication Critical patent/ZA943896B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
ZA943896A 1993-06-04 1994-06-03 Pharmaceutical agents for treatment of emesis ZA943896B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/072,629 US5393762A (en) 1993-06-04 1993-06-04 Pharmaceutical agents for treatment of emesis

Publications (1)

Publication Number Publication Date
ZA943896B true ZA943896B (en) 1995-12-04

Family

ID=22108825

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA943896A ZA943896B (en) 1993-06-04 1994-06-03 Pharmaceutical agents for treatment of emesis

Country Status (19)

Country Link
US (1) US5393762A (cs)
EP (1) EP0627221B1 (cs)
JP (1) JP2671972B2 (cs)
KR (1) KR100190729B1 (cs)
CN (1) CN1100535C (cs)
AT (1) ATE209490T1 (cs)
AU (1) AU666077B2 (cs)
CA (1) CA2124990C (cs)
DE (1) DE69429208T2 (cs)
DK (1) DK0627221T3 (cs)
ES (1) ES2164088T3 (cs)
HU (1) HU222243B1 (cs)
IL (1) IL109802A (cs)
MY (1) MY115310A (cs)
NZ (1) NZ260674A (cs)
PT (1) PT627221E (cs)
RU (1) RU2135179C1 (cs)
TW (1) TW318791B (cs)
ZA (1) ZA943896B (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2102179C (en) * 1991-05-31 1998-10-27 Fumitaka Ito Quinuclidine derivatives
RU2114848C1 (ru) * 1991-06-20 1998-07-10 Пфайзер Инк. Фторалкоксибензиламинные производные азотсодержащих гетероциклов, фармацевтическая композиция, способ ингибирования действия вещества р у млекопитающих
EP0533280B2 (en) 1991-09-20 2004-12-01 Glaxo Group Limited Novel medical use for tachykinin antagonists
US6048859A (en) 1992-06-29 2000-04-11 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US5688806A (en) * 1993-03-04 1997-11-18 Pfizer Inc. Spiroazacyclic derivatives as substance P antagonists
GB9305718D0 (en) 1993-03-19 1993-05-05 Glaxo Group Ltd Medicaments
US5576317A (en) * 1994-12-09 1996-11-19 Pfizer Inc. NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis
KR19980703354A (ko) * 1995-03-27 1998-10-15 나카토미히로타카 피페리딘 유도체
TW340842B (en) * 1995-08-24 1998-09-21 Pfizer Substituted benzylaminopiperidine compounds
TW458774B (en) * 1995-10-20 2001-10-11 Pfizer Antiemetic pharmaceutical compositions
US6329396B1 (en) 1996-06-10 2001-12-11 Pfizer Inc. Substituted benzylaminopiperidine compounds
GB9708484D0 (en) * 1997-04-25 1997-06-18 Merck Sharp & Dohme Therapeutic agents
JP2002506459A (ja) * 1997-06-27 2002-02-26 メルク シヤープ エンド ドーム リミテツド 置換された３−（ベンジルアミノ）ピペリジン誘導体およびその治療薬としての使用
WO2000032192A1 (en) * 1998-11-27 2000-06-08 Takeda Chemical Industries, Ltd. Drugs
NZ501211A (en) * 1999-01-29 2001-10-26 Pfizer Prod Inc Pharmaceutical composition comprising macrolide antibiotic like erythromycin and a Substance P antagonist, and method for treating cancer, bacterial and protozoal infection in non-humans
US6387925B1 (en) * 1999-06-01 2002-05-14 Pfizer Inc. Polymorphs of a crystalline azo-bicyclo (2.2.2) oct-3-yl amine citrate and their pharmaceutical compositions
US6255320B1 (en) * 1999-06-01 2001-07-03 Pfizer Inc. Polymorphs of a crystalline azo-bicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions
US6262067B1 (en) * 1999-06-22 2001-07-17 Pfizer Inc. Polymorphs of a crystalline azo-bicyclo 2,2,2 OCT-3-yl amine dihydrochloride and their pharmaceutical compositions
IL142810A0 (en) * 2000-05-03 2002-03-10 Pfizer Prod Inc Pharmaceutical uses for fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
RU2197961C2 (ru) * 2000-07-17 2003-02-10 Центр по разработке эластомеров Казанского государственного технологического университета Средство для профилактики и купирования тошноты и рвоты
RU2183118C1 (ru) * 2001-07-12 2002-06-10 Государственный научный центр РФ Институт медико-биологических проблем РАН Способ профилактики вестибуловегетативных расстройств у человека в условиях воздействий, вызывающих укачивание
CN1529600A (zh) * 2001-07-20 2004-09-15 �Ʒ� Nk-1受体拮抗剂在改变狗、猫和马的不需要行为中的用途
AU2005216706B2 (en) 2004-01-30 2007-11-29 Pfizer Products Inc. NK-1 receptor antagonists anesthesia recovery
BRPI0506496B8 (pt) * 2004-01-30 2022-09-20 Pfizer Prod Inc composição farmacêutica com tolerância melhorada no local de injeção compreendendo sulfobutiléter-ß-ciclodextrina e seu uso no tratamento de êmese composição farmacêutica com tolerância melhorada no local de injeção compreendendo sulfobutiléter-ß-ciclodextrina e seu uso no tratamento de êmese composição farmacêutica com tolerância melhorada no local de injeção compreendendo sulfobutiléter-ß-ciclodextrina e seu uso no tratamento de êmese
RU2320659C9 (ru) * 2004-02-02 2008-07-20 Пфайзер Продактс Инк. Способы получения 1-(2s, 3s)-2-бензгидрил-n-(5-трет-бутил-2-метоксибензил)хинуклидин-3-амина в виде камфорсульфатной соли, цитратной соли и свободного основания и промежуточное соединение
WO2014197137A1 (en) * 2013-04-29 2014-12-11 Howard Brooks-Korn Diversion-resistant formulation
US11040947B2 (en) 2017-03-22 2021-06-22 The Research Foundation For The State University Of New York Substituted quinazolines as matrix metalloproteinase-9 hemopexin domain inhibitors

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8527052D0 (en) * 1985-11-02 1985-12-04 Beecham Group Plc Compounds
WO1990005525A1 (en) * 1988-11-23 1990-05-31 Pfizer Inc. Quinuclidine derivatives as substance p antagonists
US5232929A (en) * 1990-11-28 1993-08-03 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
ATE113947T1 (de) * 1990-06-01 1994-11-15 Pfizer 3-amino-2-arylchinuclidine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
ATE116317T1 (de) * 1990-07-23 1995-01-15 Pfizer Chinuclidinderivate.
EP0550635B1 (en) * 1990-09-28 1995-04-19 Pfizer Inc. Fused ring analogs of nitrogen containing nonaromatic heterocycles
AU652407B2 (en) * 1991-01-10 1994-08-25 Pfizer Inc. N-alkyl quinuclidinium salts as substance P antagonists
CA2105302C (en) * 1991-03-01 1996-11-12 Pfizer Limited 1-azabicyclo¬3.2.2.|nonan-3-amine derivatives
JPH0794440B2 (ja) * 1991-03-26 1995-10-11 フアイザー・インコーポレイテツド 置換ピペリジンの立体選択的製造
CA2109415C (en) * 1991-05-22 1998-12-29 Fumitaka Ito Substituted 3-aminoquinuclidines
CA2102179C (en) * 1991-05-31 1998-10-27 Fumitaka Ito Quinuclidine derivatives
RU2114848C1 (ru) * 1991-06-20 1998-07-10 Пфайзер Инк. Фторалкоксибензиламинные производные азотсодержащих гетероциклов, фармацевтическая композиция, способ ингибирования действия вещества р у млекопитающих
TW202432B (cs) * 1991-06-21 1993-03-21 Pfizer
EP0533280B2 (en) * 1991-09-20 2004-12-01 Glaxo Group Limited Novel medical use for tachykinin antagonists
ES2174836T3 (es) * 1991-09-26 2002-11-16 Pfizer Heterrociclos nitrogenados triciclicos condesados como antagonistas de receptor de la sustancia p.
CA2324959C (en) * 1991-11-12 2002-11-12 Pfizer Limited Phthalimido compounds as intermediates for producing substance p receptor antagonists
JP2656702B2 (ja) * 1992-03-23 1997-09-24 ファイザー製薬株式会社 ペプチド性キヌクリジン
DK0641328T3 (da) * 1992-05-18 2002-05-21 Pfizer Broforbundne, azabicykliske derivater som substans P-antagonister
DK0675886T3 (da) * 1992-12-10 2000-09-18 Pfizer Aminomethylensubstituerede ikke-aromatiske heterocykler og deres anvendelse som substance P-antagonister
US5688806A (en) * 1993-03-04 1997-11-18 Pfizer Inc. Spiroazacyclic derivatives as substance P antagonists
GB9305718D0 (en) * 1993-03-19 1993-05-05 Glaxo Group Ltd Medicaments
EP1105789A1 (en) * 1998-08-14 2001-06-13 ViA, Inc. Mobile robotic snake

Also Published As

Publication number Publication date
AU666077B2 (en) 1996-01-25
DK0627221T3 (da) 2002-02-11
KR100190729B1 (ko) 1999-06-01
US5393762A (en) 1995-02-28
JP2671972B2 (ja) 1997-11-05
DE69429208T2 (de) 2002-05-23
CN1121806A (zh) 1996-05-08
IL109802A (en) 2002-04-21
TW318791B (cs) 1997-11-01
MY115310A (en) 2003-05-31
AU6452194A (en) 1994-12-15
EP0627221B1 (en) 2001-11-28
CN1100535C (zh) 2003-02-05
NZ260674A (en) 2000-07-28
HU9401676D0 (en) 1994-09-28
ATE209490T1 (de) 2001-12-15
CA2124990C (en) 1999-04-20
IL109802A0 (en) 1994-08-26
ES2164088T3 (es) 2002-02-16
EP0627221A3 (en) 1995-08-02
RU94020410A (ru) 1996-05-10
HUT71550A (en) 1995-12-28
EP0627221A2 (en) 1994-12-07
KR950000144A (ko) 1995-01-03
HU222243B1 (hu) 2003-05-28
RU2135179C1 (ru) 1999-08-27
DE69429208D1 (de) 2002-01-10
PT627221E (pt) 2002-04-29
JPH0753362A (ja) 1995-02-28

Similar Documents

Publication Publication Date Title
ZA943896B (en) Pharmaceutical agents for treatment of emesis
UA26213C2 (uk) Засіб для профілактики та лікуваhhя остеопорозу та фармацевтичhа композиція hа їх осhові
ATE211384T1 (de) Verwendung von adenosinantagonisten zur vorbeugung und behandlung von pankreatitis und ulcera
DE69716810D1 (de) 2,3-Disubstituierte-(5,6)-heteroarylkondensierte-pyrimidin-4-one
IL119207A0 (en) Treatment of tinnitus using neuroprotective agents
UA41355C2 (uk) Засіб для лікування нейро-сніду
GB9305718D0 (en) Medicaments
DK0701546T3 (da) Aromatiske acetylchlolinesteraseinhibitorer
FI911083A7 (fi) Menetelmä kolinergisina aineina käyttökelpoisten 1-atsabisyklo/2.2.1/heptaani- tai -/2.2.2/oktaani-3-oni-O-oksiimien valmistamiseksi
ES2093357T3 (es) Metodo de tratamiento de la alopecia.
ZA932415B (en) Compounds for the treatment of neurodegenerative disorders
NO944339L (no) Melatoninderivater for anvendelse ved behandling av sövnforstyrrelser
MX9707642A (es) Uso de 2-oxoindol-1-carboxamidas 3-sustituidas y sus sales de base farmaceuticamente aceptables para preparar composiciones para el tratamiento y prevencion de la enfermedad de alzheimer en mamiferos, incluyendo a humanos.
NO944340L (no) Melatoninderivater for anvendelse ved behandling av desynkroniseringstilstander
HUT70757A (en) Pharmaceutical compositions for treating skin disorders
CA2136801A1 (en) Pharmaceutical Agents for the Treatment of Disorders Caused by Helicobacter Pylori or Other Spiral Urease-Positive Gram-Negative Bacteria
FI944687A7 (fi) Koostumus likinäköisyyden ennaltaehkäisemiseksi ja hoitamiseksi
ES2150418T3 (es) Composiciones farmaceuticas que comprenden calcitonina.
HU9402578D0 (en) Medicament for treating or preventing cerebrovascular diseases
IL98200A0 (en) Pharmaceutical composition containing a derivative of substituted-l-valyl-l-prolinamide