ZA9408094B - 1-Amino-ethylindole-derivatives - Google Patents

1-Amino-ethylindole-derivatives

Info

Publication number
ZA9408094B
ZA9408094B ZA9408094A ZA9408094A ZA9408094B ZA 9408094 B ZA9408094 B ZA 9408094B ZA 9408094 A ZA9408094 A ZA 9408094A ZA 9408094 A ZA9408094 A ZA 9408094A ZA 9408094 B ZA9408094 B ZA 9408094B
Authority
ZA
South Africa
Prior art keywords
ethylindole
derivatives
amino
Prior art date
Application number
ZA9408094A
Inventor
Michael Boes
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH320193 priority Critical
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA9408094B publication Critical patent/ZA9408094B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/36Oxygen atoms in position 3, e.g. adrenochrome
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
ZA9408094A 1993-10-22 1994-10-14 1-Amino-ethylindole-derivatives ZA9408094B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH320193 1993-10-22

Publications (1)

Publication Number Publication Date
ZA9408094B true ZA9408094B (en) 1995-04-24

Family

ID=4250849

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9408094A ZA9408094B (en) 1993-10-22 1994-10-14 1-Amino-ethylindole-derivatives

Country Status (19)

Country Link
US (1) US5494928A (en)
EP (1) EP0655440A3 (en)
JP (1) JP2638752B2 (en)
KR (1) KR950011406A (en)
CN (1) CN1061341C (en)
AU (1) AU685841B2 (en)
BR (1) BR9404203A (en)
CA (1) CA2132883A1 (en)
CO (1) CO4290356A1 (en)
CZ (1) CZ260494A3 (en)
FI (1) FI944969A (en)
HU (1) HU218669B (en)
IL (1) IL111314A (en)
NO (1) NO301369B1 (en)
NZ (1) NZ264713A (en)
PL (1) PL179561B1 (en)
RU (1) RU2136662C1 (en)
TW (1) TW270114B (en)
ZA (1) ZA9408094B (en)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ318228A (en) * 1995-09-01 1999-07-29 Lilly Co Eli Indolyl neuropeptide y receptor antagonists
GB9523999D0 (en) 1995-11-23 1996-01-24 Lilly Co Eli Indolyl neuropeptide y receptor antagonists
AU3255697A (en) * 1996-06-12 1998-01-07 F. Hoffmann-La Roche Ag A process for the manufacture of 1-(amino-alkyl)-indoles
AU727654B2 (en) * 1997-06-13 2000-12-21 Yamanouchi Pharmaceutical Co., Ltd. Tricyclic pyrazole derivative
PT957080E (en) * 1997-08-07 2006-10-31 Fujimoto Brothers Co Ltd Novel ethylamine
US6960579B1 (en) 1998-05-19 2005-11-01 Alcon Manufacturing, Ltd. Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
IT1314185B1 (en) * 1998-08-21 2002-12-06 Novartis Ag A pharmaceutical composition for administration of substances soluble in aqueous media attivescarsamente
GB9819033D0 (en) * 1998-09-01 1998-10-28 Cerebrus Ltd Chemical compounds VI
GB9819019D0 (en) * 1998-09-01 1998-10-28 Cerebrus Ltd Chemical compounds II
GB9819032D0 (en) * 1998-09-01 1998-10-28 Cerebrus Ltd Chemical compounds IV
US6326379B1 (en) 1998-09-16 2001-12-04 Bristol-Myers Squibb Co. Fused pyridine inhibitors of cGMP phosphodiesterase
AU755119B2 (en) 1998-09-18 2002-12-05 Alcon Laboratories, Inc. Serotonergic 5HT2 agonists for treating glaucoma
WO2004098807A1 (en) * 2000-11-21 2004-11-18 Barsplice Products, Inc. Method of making steel couplers for joining concrete reinforcing bars
FR2788772B1 (en) * 1999-01-26 2001-03-02 Adir Novel compounds cyano-indoles serotonin reuptake inhibitors, their process for the preparation and pharmaceutical compositions containing them
FR2792313A1 (en) * 1999-04-13 2000-10-20 Synthelabo 2-aminoethyl-indole derivatives, their preparation and their therapeutic application
US6465467B1 (en) 1999-05-21 2002-10-15 Biovitrum Ab Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases
GB9918965D0 (en) * 1999-08-11 1999-10-13 Cerebrus Ltd Chemical compounds xxi
GB9918962D0 (en) * 1999-08-11 1999-10-13 Cerebrus Ltd Chemical compounds xxii
WO2001032596A1 (en) * 1999-11-05 2001-05-10 Emisphere Technologies, Inc. Phenoxy carboxylic acid compounds and compositions for delivering active agents
WO2001040183A1 (en) * 1999-12-03 2001-06-07 Alcon Universal Ltd. 1-aminoalkyl-1h-indoles for treating glaucoma
JP3585796B2 (en) 1999-12-17 2004-11-04 新光電気工業株式会社 Method of manufacturing a multilayer wiring board, and a semiconductor device
EP1132389A1 (en) 2000-03-06 2001-09-12 F. Hoffmann-La Roche Ag New aza-indolyl derivatives for the treatment of obesity
US6806285B1 (en) 2000-03-17 2004-10-19 Alcon, Inc. 5-Hydroxyl indole derivatives for treating glaucoma
US7005443B1 (en) * 2000-03-17 2006-02-28 Alcon, Inc. 5-Hydroxy indazole derivatives for treating glaucoma
US6956036B1 (en) 2000-03-17 2005-10-18 Alcon, Inc. 6-hydroxy-indazole derivatives for treating glaucoma
US7012090B1 (en) 2000-03-17 2006-03-14 Alcon, Inc. Pyranoindoles for treating glaucoma
WO2001070705A1 (en) 2000-03-17 2001-09-27 Alcon, Inc. 2-acylaminobenzimidazole derivatives for treating glaucoma
JP2003527423A (en) * 2000-03-17 2003-09-16 アルコン、インコーポレイテッド Compounds having 5-ht2 and 5-HT1A agonist activity for glaucoma treatment
US6903081B2 (en) * 2000-03-31 2005-06-07 Purdue Research Foundation Phosphoramidates and methods therefor
TWI288745B (en) 2000-04-05 2007-10-21 Daiichi Seiyaku Co Ethylenediamine derivatives
WO2001083487A1 (en) * 2000-04-28 2001-11-08 Yamanouchi Pharmaceutical Co., Ltd. Froindazole derivative
EP1328515B1 (en) * 2000-10-16 2008-08-06 F. Hoffmann-La Roche AG Indoline derivatives and their use as 5-ht2 receptor ligands
NZ525699A (en) 2000-11-20 2005-03-24 Biovitrum Ab Piperazinylpyrazines compounds as antagonists of serotonin 5-HT2 receptor
SE0004245D0 (en) 2000-11-20 2000-11-20 Pharmacia Ab Novel Compounds and Their Use
GB0030710D0 (en) * 2000-12-15 2001-01-31 Hoffmann La Roche Piperazine derivatives
US6780862B2 (en) 2000-12-20 2004-08-24 Bristol-Myers Squibb Pharma Company Aryl and aminoaryl substituted serotonin receptor agonist and antagonist ligands
WO2002051844A1 (en) 2000-12-27 2002-07-04 F. Hoffmann-La Roche Ag Indole derivatives and their use as 5-ht2b and 5-ht2c receptor ligands
JP4544820B2 (en) 2001-03-09 2010-09-15 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド Heterocyclic compounds
WO2002098860A1 (en) * 2001-06-01 2002-12-12 Alcon, Inc. Novel fused indazoles and indoles and their use for the treatment of glaucoma
KR100626255B1 (en) * 2001-06-01 2006-09-21 알콘, 인코퍼레이티드 Pyranoindazoles and their Use for the Treatment of Glaucoma
AU2002259312B2 (en) * 2001-06-01 2007-01-04 Alcon, Inc. Novel arylaminopropane analogues and their use for the treatment of glaucoma
WO2003000657A1 (en) 2001-06-20 2003-01-03 Daiichi Pharmaceutical Co., Ltd. Diamine derivatives
MXPA03011951A (en) 2001-06-20 2004-03-26 Daiichi Seiyaku Co Diamine derivatives.
US6884816B2 (en) 2001-08-31 2005-04-26 Alcon, Inc. Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
TW593302B (en) * 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
CN100484933C (en) 2002-06-19 2009-05-06 比奥维特罗姆股份公开公司 Novel pyrazine compounds, their use in preparing medicament for treating diseases correlated with serotonin
JP2006501245A (en) * 2002-08-30 2006-01-12 アルコン,インコーポレイテッド Substituted 5-chroman-5-yl - its use for the treatment of ethylamine compounds and glaucoma
US20040127395A1 (en) * 2002-09-06 2004-07-01 Desai Pragnya J. Use of histamine H4 receptor modulators for the treatment of allergy and asthma
CN1694704A (en) 2002-09-06 2005-11-09 詹森药业有限公司 Use of (1H-benzimidazole-2-yl)-(piperazineyl)- ketaderavitive and correlative compound used as histamine H4 receptor antagonist for the treatment of allergy and asthma
AU2003300915B2 (en) * 2002-12-13 2008-08-28 Alcon, Inc. Novel benzopyran analogs and their use for the treatment of glaucoma
CL2004000826A1 (en) 2003-04-25 2005-03-04 Pfizer Use of an agonist for the 5HT 2C receptor to prepare a medicament useful in the treatment of urinary incontinence caused by stress, with the proviso that the agonist not 1- [6-chloro-5- (trifluoromethyl) -2- pyridinyl] piperazine (org-129
GB0314967D0 (en) 2003-06-26 2003-07-30 Hoffmann La Roche Piperazine derivatives
WO2005053688A1 (en) * 2003-11-26 2005-06-16 Alcon, Inc. Substituted furo[2,3-g] indazoles for the treatment of glaucoma
TW200520760A (en) * 2003-12-15 2005-07-01 Alcon Inc Substituted [1,4] oxazino [2,3-g] indazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
US7129257B1 (en) 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
EP1792629A4 (en) 2004-08-25 2010-08-25 Takeda Pharmaceutical Preventives/remedies for stress urinary incontinence and method of screening the same
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
US7425572B2 (en) * 2004-12-08 2008-09-16 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
CA2602348C (en) 2005-03-31 2011-03-01 Pfizer Products Inc. Cyclopentapyridine and tetrahydroquinoline derivatives
TW200744567A (en) * 2005-09-23 2007-12-16 Alcon Inc Phenylethylamine analogs and their use for treating glaucoma
US8158617B2 (en) 2006-05-16 2012-04-17 Takeda Pharmaceutical Company Limited Fused heterocyclic compound and use thereof
WO2007149728A2 (en) * 2006-06-20 2007-12-27 Alcon Research, Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
DE602007012254D1 (en) * 2006-07-14 2011-03-10 Pfizer Prod Inc Tartrate salt of (7S) -7-a (5-fluoro-2-methylbenzyl) oxyü-2-a (2R) -2-methylpiperazin-1-ylü-6,7-dihydro-5H-cyclopentaäbüpyridin
EP2789338A3 (en) 2007-11-15 2015-01-14 Takeda Pharmaceutical Company Limited Condensed pyridine derivate and use thereof
DE102008009609A1 (en) 2008-02-18 2009-08-20 Freie Universität Berlin Substituted 4- (indol-3-yl) quinazolines and their use and production
KR101062376B1 (en) 2008-04-10 2011-09-06 한국화학연구원 New indole carboxylic acid bispyridyl carboxamide derivative, a composition containing as active ingredient, methods for their manufacture and this
EP2510949A4 (en) 2009-12-11 2013-11-13 Astellas Pharma Inc Therapeutic agent for fibromyalgia
WO2012030953A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level
CN102702066A (en) * 2011-03-28 2012-10-03 苏州百灵威超精细材料有限公司 Novel method for preparing intermediate 6-chloro-5-fluoroindole used for synthesizing anticancer and weight-reducing medicine
WO2014153203A2 (en) * 2013-03-14 2014-09-25 Ossifi Inc. Alkyl-amine harmine derivatives for promoting bone growth

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791899A (en) * 1971-11-26 1973-05-24 Ciba Geigy Method of preparing n-substituted indoles
IE37234B1 (en) * 1972-02-14 1977-06-08 Ayerst Mckenna & Harrison Fused-ring indole derivatives
US3904617A (en) * 1972-10-12 1975-09-09 Ayerst Mckenna & Harrison Process for preparing new heterocyclic derivatives
DE2430682A1 (en) * 1974-06-26 1976-01-15 Bayer Ag Indolyl-mono-azo dyes
FR2355006B1 (en) * 1976-06-17 1979-06-01 Labaz
DE2824447A1 (en) * 1978-06-03 1979-12-13 Cassella Ag 8-Substd. 2,4,5,6-tetra:hydro-1H-pyrazino-(2,3,1-jk)-carbazole(s) - are psychotropic agents, esp. useful as antidepressives
DE3022648A1 (en) * 1979-06-29 1981-01-15 Sandoz Ag New organic compounds, their production and pharmaceutical preparations containing these compounds
FR2564465B1 (en) * 1984-05-16 1986-10-03 Cortial New 1.3-Diamino-2-propanols, their preparation methods and their therapeutic applications
PH23498A (en) * 1984-08-06 1989-08-16 Sterling Drug Inc 3-carbonyl-1-aminoalkyl-1h-indoles,composition and use thereof
US4660060A (en) * 1985-06-17 1987-04-21 The Hilton-Davis Chemical Co. Imaging systems containing 3-(indol-3-yl)-3-(4-substituted aminophenyl)phthalides
IL89167A (en) * 1988-02-10 1994-02-27 Hoffmann La Roche Substituted pyrroles, their manufacture and pharmaceutical compositions containing them
FR2679561A1 (en) * 1991-07-26 1993-01-29 Schneider Marc New (1-indolyl)alkylamine derivatives substituted by a chain having carbonyl groups conjugated with an aromatic ring
US5252732A (en) * 1991-09-09 1993-10-12 Merck & Co., Inc. D-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl and O-alkynylheteroarylmacrolides having immunosuppressive activity
EP0572863A1 (en) * 1992-06-05 1993-12-08 F. Hoffmann-La Roche Ag CNS pyrazinoindoles
US5310901A (en) * 1993-03-05 1994-05-10 Merck & Co., Inc. O-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl and O-alkynlheteroarylrapamycin derivatives

Also Published As

Publication number Publication date
CA2132883A1 (en) 1995-04-23
EP0655440A2 (en) 1995-05-31
PL179561B1 (en) 2000-09-29
NZ264713A (en) 1996-05-28
FI944969A0 (en) 1994-10-21
FI944969D0 (en)
EP0655440A3 (en) 1996-11-06
IL111314D0 (en) 1994-12-29
HU218669B (en) 2000-10-28
JP2638752B2 (en) 1997-08-06
KR950011406A (en) 1995-05-15
PL305543A1 (en) 1995-05-02
CN1105988A (en) 1995-08-02
HUT70848A (en) 1995-11-28
NO301369B1 (en) 1997-10-20
FI944969A (en) 1995-04-23
NO943999L (en) 1995-04-24
TW270114B (en) 1996-02-11
IL111314A (en) 1999-08-17
AU685841B2 (en) 1998-01-29
RU94037964A (en) 1996-09-10
HU9402983D0 (en) 1995-02-28
CO4290356A1 (en) 1996-04-17
JPH07149723A (en) 1995-06-13
NO943999D0 (en) 1994-10-21
BR9404203A (en) 1995-07-04
AU7583794A (en) 1995-05-11
CN1061341C (en) 2001-01-31
RU2136662C1 (en) 1999-09-10
CZ260494A3 (en) 1995-10-18
US5494928A (en) 1996-02-27

Similar Documents

Publication Publication Date Title
DE69433664D1 (en) Foetal-sensor
DE69400208D1 (en) Olionukleotidalkylphosphonate und -phosphonothioate
DE69400639D1 (en) Rehydratationsgetraenk
DE69310548D1 (en) Knieorthese
DE59407886D1 (en) Substituierte aryl-ketoenolheterocyclen
DE69421914D1 (en) Ekg-sensor
DE69426415D1 (en) Intrapulmonares hormonabgabesystem
DE69401926D1 (en) Hydroxamsäurederivate
DE69432758D1 (en) Therapeutisch wirksame peptidderivate
DE69410992D1 (en) MODULARE HüFTPROTHESE
KR100258902B1 (en) Humanizedantibodiesandusesthereof
DE69410459D1 (en) Statistische blockcopolymere
DE69429631D1 (en) Conotoxinpeptide
DE69432627D1 (en) Polymergebundene camptothecin-derivate
DE69413240D1 (en) 5-arylindolderivate
ZA9401467B (en) Positive section
HRP940370B1 (en) New sulfonylaminopyrimidines
SG68570A1 (en) Substituted n-piperridino-pyrazole-3-carboxamide
ZW8594A1 (en) Substituted azadioxacycbalkenes
ZA9405171B (en) Substituted 2-phenylpzridines
DE69427706D1 (en) cryptophycine
HU9302966D0 (en) Imidazopyridine-derivatives
ZA9408094B (en) 1-Amino-ethylindole-derivatives
ZA9407119B (en) Androstenones
LU91216I2 (en) Noxafil-posaconazole