ZA939214B - PEG hydrazone and PEG oxime linkage forming reagents and protein derivatives thereof - Google Patents

PEG hydrazone and PEG oxime linkage forming reagents and protein derivatives thereof

Info

Publication number
ZA939214B
ZA939214B ZA939214A ZA939214A ZA939214B ZA 939214 B ZA939214 B ZA 939214B ZA 939214 A ZA939214 A ZA 939214A ZA 939214 A ZA939214 A ZA 939214A ZA 939214 B ZA939214 B ZA 939214B
Authority
ZA
South Africa
Prior art keywords
peg
hydrazone
protein derivatives
forming reagents
oxime linkage
Prior art date
Application number
ZA939214A
Inventor
David E Wright
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of ZA939214B publication Critical patent/ZA939214B/en

Links

ZA939214A 1992-12-09 1993-12-08 PEG hydrazone and PEG oxime linkage forming reagents and protein derivatives thereof ZA939214B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98773992A 1992-12-09 1992-12-09

Publications (1)

Publication Number Publication Date
ZA939214B true ZA939214B (en) 1995-06-08

Family

ID=25533514

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA939214A ZA939214B (en) 1992-12-09 1993-12-08 PEG hydrazone and PEG oxime linkage forming reagents and protein derivatives thereof

Country Status (2)

Country Link
CA (1) CA2110543A1 (en)
ZA (1) ZA939214B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004099231A2 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
DE10209821A1 (en) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Coupling of proteins to a modified polysaccharide
DE10209822A1 (en) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Coupling of low molecular weight substances to a modified polysaccharide
KR101045422B1 (en) 2002-09-11 2011-06-30 프레제니우스 카비 도이치란트 게엠베하 Method of producing hydroxyalkyl starch derivatives
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
CA2547140A1 (en) * 2003-11-24 2005-06-09 Neose Technologies, Inc. Glycopegylated erythropoietin
DE202005021885U1 (en) 2004-03-11 2011-03-03 Fresenius Kabi Deutschland Gmbh Hydroxyalkyl starch-protein conjugates prepared by reductive amination
WO2006010143A2 (en) 2004-07-13 2006-01-26 Neose Technologies, Inc. Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
PL2586456T3 (en) 2004-10-29 2016-07-29 Ratiopharm Gmbh Remodeling and glycopegylation of fibroblast growth factor (FGF)
NZ555308A (en) 2004-12-22 2010-10-29 Ambrx Inc Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
EP2514757A3 (en) 2005-01-10 2014-03-05 ratiopharm GmbH Glycopegylated granulocyte colony stimulating factor
EP1871795A4 (en) 2005-04-08 2010-03-31 Biogenerix Ag Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
EP1954710B1 (en) 2005-11-08 2011-03-02 Ambrx, Inc. Accelerants for the modification of non-natural amino acids and non-natural amino acid polypeptides
CN101448512B (en) 2005-12-14 2015-11-25 Ambrx公司 Purposes containing alpha-non-natural amino acid and the compositions of polypeptide, the method relating to alpha-non-natural amino acid and polypeptide and alpha-non-natural amino acid and polypeptide
US9187532B2 (en) 2006-07-21 2015-11-17 Novo Nordisk A/S Glycosylation of peptides via O-linked glycosylation sequences
US20100075375A1 (en) 2006-10-03 2010-03-25 Novo Nordisk A/S Methods for the purification of polypeptide conjugates
KR20150064246A (en) 2007-04-03 2015-06-10 바이오제너릭스 게엠베하 Methods of treatment using glycopegylated g―csf
EP2170919B8 (en) 2007-06-12 2016-01-20 ratiopharm GmbH Improved process for the production of nucleotide sugars
EP2070950A1 (en) 2007-12-14 2009-06-17 Fresenius Kabi Deutschland GmbH Hydroxyalkyl starch derivatives and process for their preparation
WO2009108806A1 (en) 2008-02-27 2009-09-03 Novo Nordisk A/S Conjugated factor viii molecules

Also Published As

Publication number Publication date
CA2110543A1 (en) 1994-06-10

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