ZA9209315B - 17-spirofuran-3'-ylidene steroids. - Google Patents

17-spirofuran-3'-ylidene steroids.

Info

Publication number
ZA9209315B
ZA9209315B ZA929315A ZA929315A ZA9209315B ZA 9209315 B ZA9209315 B ZA 9209315B ZA 929315 A ZA929315 A ZA 929315A ZA 929315 A ZA929315 A ZA 929315A ZA 9209315 B ZA9209315 B ZA 9209315B
Authority
ZA
South Africa
Prior art keywords
spirofuran
ylidene
steroids
ylidene steroids
Prior art date
Application number
ZA929315A
Inventor
Johannes Antonius Mar Hamersma
Everardus Otto Maria Orlemans
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP91203366 priority Critical
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of ZA9209315B publication Critical patent/ZA9209315B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
ZA929315A 1991-12-20 1992-12-01 17-spirofuran-3'-ylidene steroids. ZA9209315B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP91203366 1991-12-20

Publications (1)

Publication Number Publication Date
ZA9209315B true ZA9209315B (en) 1993-05-24

Family

ID=8208088

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA929315A ZA9209315B (en) 1991-12-20 1992-12-01 17-spirofuran-3'-ylidene steroids.

Country Status (17)

Country Link
US (1) US5292878A (en)
EP (1) EP0549041B1 (en)
JP (1) JP3462515B2 (en)
KR (1) KR100287513B1 (en)
AT (1) AT128983T (en)
AU (1) AU655858B2 (en)
CA (1) CA2084431C (en)
DE (2) DE69205405D1 (en)
DK (1) DK0549041T3 (en)
ES (1) ES2081040T3 (en)
FI (1) FI104178B1 (en)
GR (1) GR3018630T3 (en)
HK (1) HK1002033A1 (en)
MX (1) MX9207394A (en)
NO (1) NO302525B1 (en)
NZ (1) NZ245520A (en)
ZA (1) ZA9209315B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2100514C (en) * 1992-07-29 2005-03-29 Johannes A. M. Hamersma 17-spiromethylene steroids
WO1999025360A2 (en) 1997-11-14 1999-05-27 Akzo Nobel N.V. Progestogen-antiprogestogen regimens
US6020328A (en) * 1998-03-06 2000-02-01 Research Triangle Institute 20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
DE69942578D1 (en) 1998-05-22 2010-08-26 Univ R Bifunctional molecules and therapies based on them.
US6262042B1 (en) 1998-05-29 2001-07-17 Research Triangle Institute 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
US5962444A (en) * 1998-05-29 1999-10-05 Research Triangle Institute 17β-nitro-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
EP1178807B1 (en) * 1999-04-29 2004-09-29 Akzo Nobel N.V. Use of org 33245 in combined intermittent hormone therapy and contraception
US6043235A (en) * 1999-07-21 2000-03-28 Research Triangle Institute 11β-aryl-17, 17-spirothiolane-substituted steroids
US7426602B2 (en) * 2004-01-08 2008-09-16 Topside Research, Llc Switch for bus optimization
TW200531977A (en) 2004-03-25 2005-10-01 Akzo Nobel Nv Progesterone receptor modulators
WO2007035716A2 (en) 2005-09-16 2007-03-29 Raptor Pharmaceutical Inc. Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
DE602007004081D1 (en) 2006-02-17 2010-02-11 Janssen Pharmaceutica Nv 17-phosphoro-steroid derivatives as progesterone receptor modulators
PT1989217E (en) 2006-02-17 2012-08-30 Janssen Pharmaceutica Nv 11-phosphorous steroid derivatives useful as progesterone receptor modulators
EP2078032B1 (en) 2006-10-24 2017-08-02 Repros Therapeutics Inc. Compositions and methods for suppressing endometrial proliferation
TWI539953B (en) 2008-04-28 2016-07-01 Repros Therapeutics Inc For the composition and methods of treating breast cancer
CA2969926C (en) 2009-02-20 2018-05-15 2-Bbb Medicines B.V. Glutathione-based drug delivery system
US8673968B2 (en) * 2009-04-06 2014-03-18 Evestra, Inc. Progesterone antagonists
CN101926806A (en) * 2009-06-24 2010-12-29 天津金耀集团有限公司 Application of 17 phosphorus estrogen compound in preparation of emergency contraception
NZ602525A (en) 2010-03-22 2014-01-31 Repros Therapeutics Inc Compositions and methods for non-toxic delivery of antiprogestins
WO2011157443A1 (en) 2010-06-17 2011-12-22 N.V. Organon (11b,17a)-11-(4-(2-11c-acetyl)phenyl)-17,23-epoxy-19,24-dinorchola-4,9,20-trien-3-one
US9096641B2 (en) 2013-06-05 2015-08-04 Evestra, Inc. Imidazolyl progesterone antagonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0116974B1 (en) * 1983-02-18 1986-10-29 Schering Aktiengesellschaft 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them
FR2596395B1 (en) * 1986-03-26 1989-05-26 Roussel Uclaf New steroids having a spiro ring in position 17, METHOD of their preparation, their application as medicines and compositions containing them
ES2015047B3 (en) * 1986-07-23 1990-08-01 Akzo Nv Novel 18-fenilestrano.
IE60780B1 (en) * 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives
DE3866410D1 (en) * 1987-04-24 1992-01-09 Akzo Nv 11-and 11-arylestranderivate arylpregnanderivate.
DE3878198D1 (en) * 1987-12-12 1993-03-18 Akzo Nv 11-arylsteroid derivatives.

Also Published As

Publication number Publication date
CA2084431A1 (en) 1993-06-21
FI925790D0 (en)
AU3009392A (en) 1993-06-24
JP3462515B2 (en) 2003-11-05
DE69205405D1 (en) 1995-11-16
FI104178B1 (en) 1999-11-30
HK1002033A1 (en) 1998-07-24
NO924857D0 (en) 1992-12-15
CA2084431C (en) 2003-04-08
EP0549041B1 (en) 1995-10-11
DE69205405T2 (en) 1996-05-09
ES2081040T3 (en) 1996-02-16
EP0549041A1 (en) 1993-06-30
US5292878A (en) 1994-03-08
GR3018630T3 (en) 1996-04-30
MX9207394A (en) 1993-07-30
AT128983T (en) 1995-10-15
NO924857L (en) 1993-06-21
FI925790A (en) 1993-06-21
FI925790A0 (en) 1992-12-18
NO302525B1 (en) 1998-03-16
JPH05255380A (en) 1993-10-05
KR100287513B1 (en) 2001-05-02
NZ245520A (en) 1995-02-24
FI104178B (en) 1999-11-30
DK0549041T3 (en) 1996-01-29
AU655858B2 (en) 1995-01-12

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