ZA916905B - 1,2,5,6-tetrahydropyridine oxine derivatives - Google Patents
1,2,5,6-tetrahydropyridine oxine derivativesInfo
- Publication number
- ZA916905B ZA916905B ZA916905A ZA916905A ZA916905B ZA 916905 B ZA916905 B ZA 916905B ZA 916905 A ZA916905 A ZA 916905A ZA 916905 A ZA916905 A ZA 916905A ZA 916905 B ZA916905 B ZA 916905B
- Authority
- ZA
- South Africa
- Prior art keywords
- tetrahydropyridine
- oxine derivatives
- oxine
- derivatives
- tetrahydropyridine oxine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909019095A GB9019095D0 (en) | 1990-09-01 | 1990-09-01 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA916905B true ZA916905B (en) | 1992-08-26 |
Family
ID=10681500
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA916905A ZA916905B (en) | 1990-09-01 | 1991-08-30 | 1,2,5,6-tetrahydropyridine oxine derivatives |
Country Status (10)
Country | Link |
---|---|
US (1) | US5314901A (fr) |
EP (1) | EP0546005A1 (fr) |
JP (1) | JPH06500325A (fr) |
AU (1) | AU8442791A (fr) |
GB (1) | GB9019095D0 (fr) |
IE (1) | IE913069A1 (fr) |
MX (1) | MX9100884A (fr) |
PT (1) | PT98824A (fr) |
WO (1) | WO1992004323A1 (fr) |
ZA (1) | ZA916905B (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5208343A (en) * | 1992-03-24 | 1993-05-04 | Warner-Lambert Company | Tetrahydropyridine oxime compounds |
EP2275096A3 (fr) * | 2005-08-26 | 2011-07-13 | Braincells, Inc. | Neurogenese par modulation des recepteurs muscariniques |
EP2258359A3 (fr) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenèse par modulation des récepteurs muscariniques avec sabcomeline |
JP2009512711A (ja) | 2005-10-21 | 2009-03-26 | ブレインセルス,インコーポレイティド | Pde阻害による神経新生の調節 |
EP2314289A1 (fr) | 2005-10-31 | 2011-04-27 | Braincells, Inc. | Modulation de la neurogenese dont la médiation est assurée par récepteur gaba |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
JP2009536669A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス,インコーポレイティド | アンジオテンシン調節による神経新生 |
CA2651862A1 (fr) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenese induite par le recepteur 5ht |
US7998971B2 (en) | 2006-09-08 | 2011-08-16 | Braincells Inc. | Combinations containing a 4-acylaminopyridine derivative |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
CN110546153B (zh) * | 2017-04-27 | 2022-09-06 | 巴斯夫欧洲公司 | 制备旋光2,3-二氢噻唑并[3,2-a]嘧啶-4-鎓化合物的方法 |
TWI797167B (zh) * | 2018-09-28 | 2023-04-01 | 德商巴地斯顏料化工廠 | 用於製備光學活性嘧啶鎓化合物之方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE56226B1 (en) * | 1982-04-14 | 1991-05-22 | Beecham Group Plc | Substituted azabicyclo compounds,process for their preparation and pharmaceutical compositions containing them |
IL81610A (en) * | 1986-02-27 | 1990-12-23 | Roussel Uclaf | Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them |
GB8615785D0 (en) * | 1986-06-27 | 1986-08-06 | Beecham Group Plc | Compounds |
ES2061502T3 (es) * | 1986-06-27 | 1994-12-16 | Beecham Group Plc | Nuevos n-heterociclos biciclicos puenteados. |
US4710508A (en) * | 1986-12-08 | 1987-12-01 | Warner-Lambert Company | O-substituted tetrahydropyridine oxime cholinergic agents |
US4786648A (en) * | 1986-12-08 | 1988-11-22 | Warner-Lambert Company | O-substituted tetrahydropyridine oxime cholinergic agents |
US4798841A (en) * | 1987-03-31 | 1989-01-17 | Warner-Lambert Company | Tetrahydropyridine oxime cholinergic agents and method of treatment |
ATE133415T1 (de) * | 1987-04-15 | 1996-02-15 | Beecham Group Plc | Am brückenkopf substituierte azabicyclenderivate |
IT1203971B (it) * | 1987-04-24 | 1989-02-23 | Roussel Maestretti Spa | Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti |
IT1222526B (it) * | 1987-08-21 | 1990-09-05 | Roussel Maestretti Spa | Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali |
IT1222529B (it) * | 1987-08-21 | 1990-09-05 | Roussel Maestretti Spa | Derivati dell' ossima della 1,2,5,6-tetraidropirdin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali |
IL88156A (en) * | 1987-11-13 | 1997-02-18 | Novo Nordisk As | Azacyclic compounds their preparation and pharmaceutical compositions containing them |
IT1233446B (it) * | 1987-12-30 | 1992-04-01 | Roussel Maestretti Spa | Derivati della 3 piperidinocarbaldeide ossima, loro procedimento di preparazione e loro applicazione come farmaci |
AU3301689A (en) * | 1988-04-15 | 1989-10-26 | Beecham Group Plc | 1-azabicyclo-alkyl derivatives |
IT1227436B (it) * | 1988-10-28 | 1991-04-11 | Roussel Maestretti Spa | Derivati di 1-azabicicloalcani, loro procedimento di preparazione e loro applicazione come farmaci |
US4937239A (en) * | 1989-02-13 | 1990-06-26 | Warner-Lambert Company | Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents |
ES2219636T3 (es) * | 1989-04-13 | 2004-12-01 | Beecham Group P.L.C. | Nuevos compuestos. |
-
1990
- 1990-09-01 GB GB909019095A patent/GB9019095D0/en active Pending
-
1991
- 1991-08-29 JP JP3514390A patent/JPH06500325A/ja active Pending
- 1991-08-29 AU AU84427/91A patent/AU8442791A/en not_active Abandoned
- 1991-08-29 EP EP91915341A patent/EP0546005A1/fr not_active Ceased
- 1991-08-29 US US07/975,938 patent/US5314901A/en not_active Expired - Fee Related
- 1991-08-29 WO PCT/GB1991/001456 patent/WO1992004323A1/fr not_active Application Discontinuation
- 1991-08-30 MX MX9100884A patent/MX9100884A/es unknown
- 1991-08-30 IE IE306991A patent/IE913069A1/en unknown
- 1991-08-30 ZA ZA916905A patent/ZA916905B/xx unknown
- 1991-08-30 PT PT98824A patent/PT98824A/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
GB9019095D0 (en) | 1990-10-17 |
MX9100884A (es) | 1992-05-04 |
AU8442791A (en) | 1992-03-30 |
PT98824A (pt) | 1992-07-31 |
WO1992004323A1 (fr) | 1992-03-19 |
US5314901A (en) | 1994-05-24 |
EP0546005A1 (fr) | 1993-06-16 |
JPH06500325A (ja) | 1994-01-13 |
IE913069A1 (en) | 1992-03-11 |
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