ZA9104536B - 8-lower alkyl-5-cycloalkyl or 5-cycloakenyl substituted benzazepines and pharmaceutical compositions containing them - Google Patents

8-lower alkyl-5-cycloalkyl or 5-cycloakenyl substituted benzazepines and pharmaceutical compositions containing them

Info

Publication number
ZA9104536B
ZA9104536B ZA914536A ZA9104536A ZA9104536B ZA 9104536 B ZA9104536 B ZA 9104536B ZA 914536 A ZA914536 A ZA 914536A ZA 9104536 A ZA9104536 A ZA 9104536A ZA 9104536 B ZA9104536 B ZA 9104536B
Authority
ZA
South Africa
Prior art keywords
cycloakenyl
cycloalkyl
lower alkyl
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA914536A
Inventor
Wei Kong Chang
Kong Chang Wei
Joseph A Kozlowski
A Kozlowski Joseph
Derek B Lowe
B Lowe Derek
Joel Gilbert Berger
Gilbert Berger Joel
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US53896590A priority Critical
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA9104536B publication Critical patent/ZA9104536B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
ZA914536A 1990-06-15 1991-06-13 8-lower alkyl-5-cycloalkyl or 5-cycloakenyl substituted benzazepines and pharmaceutical compositions containing them ZA9104536B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US53896590A true 1990-06-15 1990-06-15

Publications (1)

Publication Number Publication Date
ZA9104536B true ZA9104536B (en) 1992-03-25

Family

ID=24149189

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA914536A ZA9104536B (en) 1990-06-15 1991-06-13 8-lower alkyl-5-cycloalkyl or 5-cycloakenyl substituted benzazepines and pharmaceutical compositions containing them

Country Status (6)

Country Link
AU (1) AU8201591A (en)
IE (1) IE912031A1 (en)
IL (1) IL98487D0 (en)
PT (1) PT97984A (en)
WO (1) WO1991019698A1 (en)
ZA (1) ZA9104536B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5241065A (en) * 1992-02-25 1993-08-31 Schering Corporation 2,3,4,5-tetrahydro-1h-3-benzazepines having anti-psychotic activity
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
EP1572215B1 (en) 2002-12-20 2009-09-02 Glaxo Group Limited Benzo[d]azepine derivatives for the treatment of neurological disorders
CN1805938B (en) 2003-06-17 2010-06-16 艾尼纳制药公司 Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases
PL2332921T3 (en) 2003-06-17 2016-08-31 Arena Pharm Inc 8-Chloro-1 -methyl-2,3,4,5-tetrahydro-1 H-3benzazapine Hydrochloride
WO2005042491A1 (en) * 2003-10-22 2005-05-12 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
KR101281919B1 (en) 2004-12-21 2013-07-03 아레나 파마슈티칼스, 인크. Crystalline forms of (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride
EP2322162A1 (en) 2004-12-23 2011-05-18 Arena Pharmaceuticals, Inc. 5HT2C receptor modulator compositions and methods of use
WO2007120517A2 (en) 2006-04-03 2007-10-25 Arena Pharmaceuticals, Inc. Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto
JP5404414B2 (en) 2006-12-05 2014-01-29 アリーナ ファーマシューティカルズ, インコーポレイテッド Method for preparing (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and its intermediates
US8822727B2 (en) 2008-03-04 2014-09-02 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
EP2443080A2 (en) 2009-06-18 2012-04-25 Arena Pharmaceuticals, Inc. Process for the preparation of 5-ht2c receptor agonists
KR20130112848A (en) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. Processes for the preparation of 5-ht2c receptor agonists
CA2808909A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
AU2011296033A1 (en) 2010-09-01 2013-04-04 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-HT2C agonists
EP3485878A1 (en) 2010-09-01 2019-05-22 Arena Pharmaceuticals, Inc. Modified-release dosage forms of 5-ht2c agonists useful for weight management
SG10201506896RA (en) 2010-09-01 2015-10-29 Arena Pharm Inc Administration of lorcaserin to individuals with renal impairment
KR20150070249A (en) 2012-10-09 2015-06-24 아레나 파마슈티칼스, 인크. Method of weight management

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA8802080B (en) * 1987-03-27 1989-04-26 Schering Corp Substituted benzazepines,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
PT97984A (en) 1992-03-31
IE912031A1 (en) 1991-12-18
IL98487D0 (en) 1992-07-15
AU8201591A (en) 1992-01-07
WO1991019698A1 (en) 1991-12-26

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