ZA9004582B - Monokine activity interference - Google Patents

Monokine activity interference

Info

Publication number
ZA9004582B
ZA9004582B ZA904582A ZA9004582A ZA9004582B ZA 9004582 B ZA9004582 B ZA 9004582B ZA 904582 A ZA904582 A ZA 904582A ZA 9004582 A ZA9004582 A ZA 9004582A ZA 9004582 B ZA9004582 B ZA 9004582B
Authority
ZA
South Africa
Prior art keywords
monokine activity
activity interference
interference
monokine
Prior art date
Application number
ZA904582A
Inventor
Nabil Hanna
Hanna Nabil
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US36538789A priority Critical
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA9004582B publication Critical patent/ZA9004582B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
ZA904582A 1989-06-13 1990-06-13 Monokine activity interference ZA9004582B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US36538789A true 1989-06-13 1989-06-13

Publications (1)

Publication Number Publication Date
ZA9004582B true ZA9004582B (en) 1991-06-26

Family

ID=23438695

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA904582A ZA9004582B (en) 1989-06-13 1990-06-13 Monokine activity interference

Country Status (7)

Country Link
EP (1) EP0403251A3 (en)
JP (1) JPH04506215A (en)
AU (1) AU5921890A (en)
CA (1) CA2058952A1 (en)
IE (1) IE902138A1 (en)
WO (1) WO1990015534A1 (en)
ZA (1) ZA9004582B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0542795T5 (en) * 1990-08-03 1998-09-07 Smithkline Beecham Corp TNF inhibitors
WO1992010190A1 (en) * 1990-12-13 1992-06-25 Smithkline Beecham Corporation Novel csaids
ZA9109797B (en) * 1990-12-13 1992-10-28 Smithkline Beecham Corp Bicyclo-5,6-dihydro-7h-pyrrolo-1,20-imidazol-7-ols and 7-ones
AU2414992A (en) * 1991-07-30 1993-03-02 Duke University Method of combatting hiv infections
DE69232516T2 (en) * 1991-10-31 2002-10-31 Univ Manchester Treatment of neurological conditions by an interleukin-i-inhibiting compound
US5783664A (en) * 1993-09-17 1998-07-21 Smithkline Beecham Corporation Cytokine suppressive anit-inflammatory drug binding proteins
US5552422A (en) * 1995-01-11 1996-09-03 Merck Frosst Canada, Inc. Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents
KR20000057137A (en) 1996-11-19 2000-09-15 스티븐 엠. 오드레 Aryl and heteroaryl substituted fused pyrrole antiinflammatory agents
RU2264403C2 (en) 1999-11-10 2005-11-20 Орто-Макнейл Фармасьютикал, Инк. Substituted 2-aryl-3-(heteroaryl)imidazo[1,2-a]-pyrimidines, pharmaceutical compositions comprising thereof and associated methods
WO2001042189A1 (en) * 1999-12-06 2001-06-14 Leo Pharma A/S AMINOBENZOPHENONES AS INHIBITORS OF IL-1β AND TNF-$g(a)
AU8479201A (en) 2000-08-10 2002-02-25 Cold Spring Harbor Lab Augmented cognitive training
CA2451008A1 (en) 2001-06-21 2003-01-03 Smithkline Beecham Corporation Imidazo¬1,2-a]pyridine derivatives for the prophylaxis and treatment of herpes viral infections
EP1432712B1 (en) 2001-10-05 2006-05-17 SmithKline Beecham Corporation Imidazo-pyridine derivatives for use in the treatment of herpes viral infection
US8188083B2 (en) 2007-06-28 2012-05-29 Abbott Laboratories Triazolopyridazines
ES2651296T3 (en) 2009-10-30 2018-01-25 Janssen Pharmaceutica, N.V. Imidazo [1,2-b] pyridazine and their use as inhibitors of PDE10
AR080754A1 (en) 2010-03-09 2012-05-09 Janssen Pharmaceutica Nv Imidazo (1,2-a) pyrazine and their use as inhibitors of PDE10
CN103764655B (en) * 2011-07-13 2017-04-12 Sk化学公司 As warp 2-pyridyl substituted imidazoles alk5 and / or inhibitor alk4
US9669035B2 (en) 2012-06-26 2017-06-06 Janssen Pharmaceutica Nv Combinations comprising PDE 2 inhibitors such as 1-aryl-4-methyl-[1,2,4]triazolo-[4,3-A]]quinoxaline compounds and PDE 10 inhibitors for use in the treatment of neurological of metabolic disorders
BR112015000459A2 (en) 2012-07-09 2017-06-27 Janssen Pharmaceutica Nv phosphodiesterase enzyme inhibitors 10

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0230574A3 (en) * 1986-01-31 1989-03-22 Yale University Pharmaceutical compositions against infections caused by lav/htlv iii virus and the use thereof
US4794114A (en) * 1986-08-19 1988-12-27 Smithkline Beckman Corporation Inhibition of interleukin-1 production by monocytes and/or macrophages
US4780470A (en) * 1986-08-19 1988-10-25 Smithkline Beckman Corporation Inhibition of interleukin-1 by monocytes and/or macrophages
US4778806A (en) * 1986-08-19 1988-10-18 Smithkline Beckman Corporation Inhibition of interleukin-1 production by monocytes and/or macrophages
IL100533A (en) * 1986-12-31 1994-05-30 Hoechst Roussel Pharma Pharmaceutical compositions containing xanthine derivatives for treating hiv and related disease states

Also Published As

Publication number Publication date
IE902138L (en) 1990-12-13
JPH04506215A (en) 1992-10-29
WO1990015534A1 (en) 1990-12-27
IE902138A1 (en) 1991-01-02
AU5921890A (en) 1991-01-08
EP0403251A3 (en) 1992-04-01
EP0403251A2 (en) 1990-12-19
CA2058952A1 (en) 1990-12-14

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