ZA8905058B - 13-alkyl-11 beta-phenyl-gonanes - Google Patents

13-alkyl-11 beta-phenyl-gonanes

Info

Publication number
ZA8905058B
ZA8905058B ZA895058A ZA8905058A ZA8905058B ZA 8905058 B ZA8905058 B ZA 8905058B ZA 895058 A ZA895058 A ZA 895058A ZA 8905058 A ZA8905058 A ZA 8905058A ZA 8905058 B ZA8905058 B ZA 8905058B
Authority
ZA
South Africa
Prior art keywords
gonanes
beta
phenyl
alkyl
Prior art date
Application number
ZA895058A
Inventor
Stefan Scholz
Scholz Stefan
Eckhard Ottow
Ottow Eckhard
Guenter Neef
Neef Guenter
Walter Elger
Elger Walter
Sybille Beier
Beier Sybille
Krzysztof Chwalisz
Chwalisz Krzysztof
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE19883822770 priority Critical patent/DE3822770A1/en
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA8905058B publication Critical patent/ZA8905058B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • C07J1/0088Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J15/00Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J33/00Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
ZA895058A 1988-07-01 1989-07-03 13-alkyl-11 beta-phenyl-gonanes ZA8905058B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19883822770 DE3822770A1 (en) 1988-07-01 1988-07-01 13-alkyl-11.beta.-phenylgonane

Publications (1)

Publication Number Publication Date
ZA8905058B true ZA8905058B (en) 1990-04-25

Family

ID=6358021

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA895058A ZA8905058B (en) 1988-07-01 1989-07-03 13-alkyl-11 beta-phenyl-gonanes

Country Status (17)

Country Link
US (2) US5273971A (en)
EP (1) EP0349481B1 (en)
JP (1) JP2956776B2 (en)
AT (1) AT129717T (en)
AU (1) AU644060B2 (en)
CA (1) CA1334668C (en)
DD (2) DD287511A5 (en)
DE (1) DE3822770A1 (en)
ES (1) ES2080079T3 (en)
GR (1) GR3018069T3 (en)
HU (1) HU208021B (en)
IE (1) IE70664B1 (en)
IL (1) IL90826A (en)
NO (1) NO180451C (en)
PT (1) PT91031B (en)
WO (1) WO1990000174A1 (en)
ZA (1) ZA8905058B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3822770A1 (en) * 1988-07-01 1990-01-04 Schering Ag 13-alkyl-11.beta.-phenylgonane
US6790971B1 (en) * 1989-02-24 2004-09-14 Aventis Pharma S.A. 19-Nor-steroids
US5707982A (en) * 1989-02-24 1998-01-13 Roussel Uclaf 19-nor-steroids
DE4018168A1 (en) * 1990-06-01 1991-12-05 Schering Ag Starting compounds for the production of 10ss-h-steroidal and a process for producing these starting compounds
DE4042004A1 (en) * 1990-12-22 1992-06-25 Schering Ag 14 (beta) -H-, 14 u. 15-en-11 (beta) aryl-4-Estrenes
EP0683172B1 (en) * 1994-05-19 1997-08-13 Akzo Nobel N.V. 11,21-Bisphenyl-19-norpregnane derivatives
DE4434488A1 (en) * 1994-09-14 1996-03-21 Schering Ag Steroidester and amides, process for their preparation and their pharmaceutical use
US5929262A (en) * 1995-03-30 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates
WO1997041145A1 (en) * 1996-05-01 1997-11-06 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services 21-substituted progesterone derivatives as new antiprogestational agents
US6900193B1 (en) * 1996-05-01 2005-05-31 The United States Of America As Represented By The Department Of Health And Human Services Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
US6020328A (en) * 1998-03-06 2000-02-01 Research Triangle Institute 20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
US6262042B1 (en) 1998-05-29 2001-07-17 Research Triangle Institute 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
US5962444A (en) * 1998-05-29 1999-10-05 Research Triangle Institute 17β-nitro-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
KR20030029640A (en) * 2000-07-28 2003-04-14 악조 노벨 엔.브이. 16alpha-methyl or ethyl substituted estrogens
JP2006519255A (en) * 2003-02-28 2006-08-24 アメリカ合衆国 17α- acetoxy -11β- (4-N, N- dimethylaminophenyl) -19-norpregna-4,9-diene-3,20-process manufacturing dione, method of making intermediates and such intermediates
TW200531977A (en) * 2004-03-25 2005-10-01 Akzo Nobel Nv Progesterone receptor modulators
US20060196449A1 (en) * 2004-09-17 2006-09-07 Mockry Eldon F Fluid heating system and method
US9517240B2 (en) 2006-09-26 2016-12-13 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
WO2008039482A2 (en) * 2006-09-26 2008-04-03 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
KR20090067198A (en) 2006-10-24 2009-06-24 레프로스 쎄라피우틱스 아이엔씨. Composition and methods for suppressing endometrial proliferation
US7784843B2 (en) * 2008-01-08 2010-08-31 Toyota Motor Engineering & Manufacturing North America, Inc. Vehicle console with sliding panel
US8172293B2 (en) * 2008-01-09 2012-05-08 Toyota Motor Engineering & Manufacturing North America, Inc. Vehicle electronic device support systems
TWI539953B (en) 2008-04-28 2016-07-01 Repros Therapeutics Inc For the composition and methods of treating breast cancer
UA110030C2 (en) 2010-03-22 2015-11-10 A method for treating endometriosis or uterine fibroids and dosage form for daily administration of the mucous vagina
KR20150130359A (en) 2013-03-12 2015-11-23 아르노 테라퓨틱스 Onapristone polymorphic forms and methods of use
US9096641B2 (en) * 2013-06-05 2015-08-04 Evestra, Inc. Imidazolyl progesterone antagonists
BR112018005999A2 (en) 2015-09-25 2019-01-08 Context Biopharma Inc methods for the production of onapristone intermediates

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3971772A (en) * 1975-01-06 1976-07-27 E. R. Squibb & Sons, Inc. Steroidal[16α,17-b]1,4-dioxanes and Steroidal[16α,17-b]1,4-dioxins
ZA8200031B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
FR2522328B1 (en) * 1982-03-01 1986-02-14 Roussel Uclaf New products derived from 3-keto structure 4.9 19-nor steroids, their process for the preparation and their use as medicaments
ES533260A0 (en) * 1983-06-15 1985-02-01 Schering Ag Process for the preparation of 13a-alkylgonanes
US4780461A (en) * 1983-06-15 1988-10-25 Schering Aktiengesellschaft 13α-alkyl-gonanes, their production, and pharmaceutical preparations containing same
FR2576025B1 (en) * 1985-01-14 1987-01-23 Roussel Uclaf New steroid substituted in position 10, their process and intermediates for preparation, their use as medicines, pharmaceutical compositions containing them
NZ214998A (en) * 1985-02-07 1989-06-28 Schering Ag 13-(methyl or ethyl)-11-beta-phenyl-gonane derivatives; preparatory processes and pharmaceutical compositions
DE3625315A1 (en) * 1986-07-25 1988-01-28 Schering Ag 11ss- (4-isopropenylphenyl) -estra-4,9-diene, their preparation and pharmaceutical compositions containing them
DE3822770A1 (en) * 1988-07-01 1990-01-04 Schering Ag 13-alkyl-11.beta.-phenylgonane
DE3832303A1 (en) * 1988-09-20 1990-04-12 Schering Ag 11.beta.-phenyl-14ssh-steroidal

Also Published As

Publication number Publication date
DD287511A5 (en) 1991-02-28
EP0349481A1 (en) 1990-01-03
PT91031B (en) 1994-12-30
DE3822770A1 (en) 1990-01-04
IL90826D0 (en) 1990-01-18
PT91031A (en) 1990-02-08
AU3856889A (en) 1990-01-23
DD295638A5 (en) 1991-11-07
US5446036A (en) 1995-08-29
JP2956776B2 (en) 1999-10-04
HU208021B (en) 1993-07-28
JPH03505727A (en) 1991-12-12
NO180451B (en) 1997-01-13
US5273971A (en) 1993-12-28
NO905609D0 (en) 1990-12-27
EP0349481B1 (en) 1995-11-02
IE892141L (en) 1990-01-01
IL90826A (en) 1994-06-24
AT129717T (en) 1995-11-15
GR3018069T3 (en) 1996-02-29
IE70664B1 (en) 1996-12-11
HUT56114A (en) 1991-07-29
NO180451C (en) 1997-04-23
AU644060B2 (en) 1993-12-02
HU894130D0 (en) 1991-06-28
ES2080079T3 (en) 1996-02-01
WO1990000174A1 (en) 1990-01-11
NO905609L (en) 1991-02-28
CA1334668C (en) 1995-03-07

Similar Documents

Publication Publication Date Title
GB2222826B (en) Antisudoral compounds
DE68926748D1 (en) Mit maleinsäureanhydrid gepfropfte polyolefinfasern
DE68925815D1 (en) Multimode-modem
DE3991334D2 (en) Elastische kniegelenkbandage
HK99396A (en) Improved brief
EP0332928A3 (en) Fire-hemming elements
IL89509A (en) Breach-cooled structure
HK199496A (en) Textprocessing arrangement
GB8804448D0 (en) Compounds
ZA8909960B (en) Piperazinyl-derivatives
HU896751D0 (en) Biocid compoisitons
IE890156L (en) Didehydro-vitamin d3 - derivatives
HUT55554A (en) Play-automaton
HU894429D0 (en) Biopsia curve
GB2224095B (en) Autotensioner
EP0351540A3 (en) Artroscopic hook-forceps
GB8825481D0 (en) Interferrometer
GB8827967D0 (en) Die-free drawing
GB2226407B (en) Characterizing well features
IE892141L (en) 13-alkyl-11ß-phenylgonanes
GB8926905D0 (en) Timepice
PL159357B1 (en) Close-set-lining
IL91818D0 (en) Substituted 9h-purines
EP0359284A3 (en) Espagnolet
YU12389A (en) Dideoxy-dihydro-carbocyclical nucleozides