ZA887660B - 1-((5-((4-substituted-1-piperazinyl)methyl)-pyrrol-2-yl or furan-2-yl)methyl-2-piperidinones useful in treating schizophrenia - Google Patents
1-((5-((4-substituted-1-piperazinyl)methyl)-pyrrol-2-yl or furan-2-yl)methyl-2-piperidinones useful in treating schizophreniaInfo
- Publication number
- ZA887660B ZA887660B ZA887660A ZA887660A ZA887660B ZA 887660 B ZA887660 B ZA 887660B ZA 887660 A ZA887660 A ZA 887660A ZA 887660 A ZA887660 A ZA 887660A ZA 887660 B ZA887660 B ZA 887660B
- Authority
- ZA
- South Africa
- Prior art keywords
- methyl
- piperidinones
- pyrrol
- piperazinyl
- furan
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10817787A | 1987-10-14 | 1987-10-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA887660B true ZA887660B (en) | 1990-06-27 |
Family
ID=22320742
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA887660A ZA887660B (en) | 1987-10-14 | 1988-10-13 | 1-((5-((4-substituted-1-piperazinyl)methyl)-pyrrol-2-yl or furan-2-yl)methyl-2-piperidinones useful in treating schizophrenia |
Country Status (9)
Country | Link |
---|---|
US (1) | US4992441A (xx) |
EP (1) | EP0312345A3 (xx) |
JP (1) | JPH01193264A (xx) |
KR (1) | KR890006629A (xx) |
AU (1) | AU2362288A (xx) |
DK (1) | DK569988A (xx) |
HU (1) | HU205758B (xx) |
NZ (1) | NZ226502A (xx) |
ZA (1) | ZA887660B (xx) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE914218A1 (en) * | 1991-09-11 | 1993-03-24 | Mcneilab Inc | Novel 4-arylpiperazines and 4-arylpiperidines |
US5569659A (en) * | 1991-09-11 | 1996-10-29 | Mcneilab, Inc. | 4-arylpiperazines and 4-arylpiperidines |
US5314885A (en) * | 1992-09-11 | 1994-05-24 | Mcneilab, Inc. | Cyclic benzylamino, benzylamido, and benzylimido antipsychotic agents |
US5622948A (en) * | 1994-12-01 | 1997-04-22 | Syntex (U.S.A.) Inc. | Pyrrole pyridazine and pyridazinone anti-inflammatory agents |
US6697957B1 (en) | 2000-05-11 | 2004-02-24 | Quickturn Design Systems, Inc. | Emulation circuit with a hold time algorithm, logic analyzer and shadow memory |
US20040147581A1 (en) * | 2002-11-18 | 2004-07-29 | Pharmacia Corporation | Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy |
DE10261130A1 (de) * | 2002-12-20 | 2004-07-01 | Grünenthal GmbH | Arzneimittel enthaltend substituierte 2,5-Diaminomethyl-1H-pyrrole |
DE102004024773A1 (de) * | 2004-05-17 | 2005-12-15 | Grünenthal GmbH | Substituierte 2,5-Diaminomethyl-1H-pyrrole |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3361609D1 (en) * | 1982-03-24 | 1986-02-06 | Prodes Sa | New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts |
NZ209876A (en) * | 1983-10-17 | 1988-03-30 | Duphar Int Res | Piperazines and pharmaceutical compositions |
EP0190472B1 (en) * | 1984-12-21 | 1989-07-12 | Duphar International Research B.V | New pharmaceutical compositions having anti-psychotic properties |
EP0241053B1 (en) * | 1986-02-27 | 1992-11-11 | Duphar International Research B.V | Aryl-substituted (n-piperidinyl)-methyl- and (n-piperazinyl) methylazoles having antipsychotic properties |
PH23898A (en) * | 1986-09-12 | 1989-12-18 | Duphar Int Res | New phenyl pyrrolidin-2-yl substituted-2-yl substituted 5-ring heterocycles having antipsycotic properties |
-
1988
- 1988-09-30 US US07/251,723 patent/US4992441A/en not_active Expired - Lifetime
- 1988-10-07 NZ NZ226502A patent/NZ226502A/en unknown
- 1988-10-11 AU AU23622/88A patent/AU2362288A/en not_active Abandoned
- 1988-10-13 DK DK569988A patent/DK569988A/da not_active Application Discontinuation
- 1988-10-13 KR KR1019880013332A patent/KR890006629A/ko not_active Application Discontinuation
- 1988-10-13 EP EP19880309581 patent/EP0312345A3/en not_active Ceased
- 1988-10-13 ZA ZA887660A patent/ZA887660B/xx unknown
- 1988-10-14 JP JP63257382A patent/JPH01193264A/ja active Pending
- 1988-10-14 HU HU885293A patent/HU205758B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HUT50162A (en) | 1989-12-28 |
JPH01193264A (ja) | 1989-08-03 |
EP0312345A2 (en) | 1989-04-19 |
DK569988D0 (da) | 1988-10-13 |
KR890006629A (ko) | 1989-06-14 |
EP0312345A3 (en) | 1990-10-17 |
NZ226502A (en) | 1991-03-26 |
US4992441A (en) | 1991-02-12 |
HU910132D0 (en) | 1991-08-28 |
HU205758B (en) | 1992-06-29 |
DK569988A (da) | 1989-04-15 |
AU2362288A (en) | 1989-04-20 |
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