ZA877132B - Drug compositions stabilized against oxidation - Google Patents
Drug compositions stabilized against oxidationInfo
- Publication number
- ZA877132B ZA877132B ZA877132A ZA877132A ZA877132B ZA 877132 B ZA877132 B ZA 877132B ZA 877132 A ZA877132 A ZA 877132A ZA 877132 A ZA877132 A ZA 877132A ZA 877132 B ZA877132 B ZA 877132B
- Authority
- ZA
- South Africa
- Prior art keywords
- against oxidation
- stabilized against
- drug compositions
- compositions stabilized
- oxidation
- Prior art date
Links
- 230000003647 oxidation Effects 0.000 title abstract 2
- 238000007254 oxidation reaction Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000005541 ACE inhibitor Substances 0.000 abstract 1
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/921,717 US4830853A (en) | 1986-10-20 | 1986-10-20 | Drug compositions stabilized against oxidation |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA877132B true ZA877132B (en) | 1989-04-26 |
Family
ID=25445868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA877132A ZA877132B (en) | 1986-10-20 | 1987-09-22 | Drug compositions stabilized against oxidation |
Country Status (20)
Country | Link |
---|---|
US (1) | US4830853A (xx) |
EP (1) | EP0264887B1 (xx) |
JP (1) | JP2703906B2 (xx) |
KR (1) | KR960000430B1 (xx) |
AT (1) | ATE67090T1 (xx) |
AU (1) | AU604061B2 (xx) |
CA (1) | CA1297024C (xx) |
DE (1) | DE3772924D1 (xx) |
DK (1) | DK174916B1 (xx) |
ES (1) | ES2040726T3 (xx) |
FI (1) | FI100091B (xx) |
GR (1) | GR3002698T3 (xx) |
HK (1) | HK85694A (xx) |
IE (1) | IE60773B1 (xx) |
NO (1) | NO874352L (xx) |
NZ (1) | NZ221954A (xx) |
PH (1) | PH25582A (xx) |
PT (1) | PT85942B (xx) |
SG (1) | SG95494G (xx) |
ZA (1) | ZA877132B (xx) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL88502A (en) * | 1987-12-14 | 1993-04-04 | Squibb & Sons Inc | Pharmaceutical compositions containing an angiotensin converting enzyme inhibitor |
DE3942145A1 (de) * | 1989-12-20 | 1991-06-27 | Boehringer Mannheim Gmbh | T-pa-solubilisierung |
US5366730A (en) * | 1989-12-20 | 1994-11-22 | Boehringer Mannheim Gmbh | Stabilized compositions having human tissue type plasminogen activator enzymatic activity |
US6300361B1 (en) * | 1990-07-25 | 2001-10-09 | Novartis Ag | Stabilized pharmaceutical compositions comprising acid donors |
HU222489B1 (hu) * | 1990-07-25 | 2003-07-28 | Novartis Ag. | Stabilizált gyógyszerkészítmények és eljárás az előállításukra |
SI9111842A (sl) * | 1991-11-25 | 1998-04-30 | Krka | Stabilna formulacija soli enalaprila, postopek za njeno pripravo in njena uporaba |
US6296871B1 (en) * | 1998-04-12 | 2001-10-02 | Ranbaxy Laboratories Limited | Stable solid pharmaceutical compositions containing enalapril maleate |
PT1121103E (pt) * | 1998-05-18 | 2007-02-28 | Takeda Pharmaceutical | Comprimidos de desintegração oral compreendendo um benzimidazole |
TR200003600T2 (tr) | 1998-06-05 | 2001-04-20 | Warner-Lambert Company | ACE inhibitörleri içeren bileşimlerin magnezyum oksit kullanılarak sabitlenmesi |
NZ333206A (en) | 1998-12-08 | 2000-07-28 | Bernard Charles Sherman | Solid pharmaceutical compositions comprising a stable magnesium salt of quinapril that acts as a ACE (Angiotensin Converting Enzyme) inhibitor |
US6555551B1 (en) * | 1999-08-31 | 2003-04-29 | Mutual Pharmaceutical Co., Inc. | Stable formulations of ACE inhibitors, and methods for preparation thereof |
US20030225124A1 (en) * | 1999-08-31 | 2003-12-04 | Spiridon Spireas | Stable formulations of ACE inhibitors, and methods for preparation thereof |
US20040157911A1 (en) * | 1999-08-31 | 2004-08-12 | Spiridon Spireas | Storage-stable and bio-stable formulations of ace inhibitors, and methods for preparation thereof |
US20050202081A1 (en) * | 2002-01-15 | 2005-09-15 | Deepak Bahl | Stable pharmaceutical compositions comprising ace inhibitor(s) |
US20050069586A1 (en) * | 2003-06-26 | 2005-03-31 | Julia Hrakovsky | Stable pharmaceutical compositions of 2-aza-bicyclo [3.3.0]-octane-3-carboxylic acid derivatives |
US6869963B2 (en) * | 2003-07-11 | 2005-03-22 | Sandoz Ag | Stable pharmaceutical compositions containing an ACE inhibitor |
EP1694308A1 (en) * | 2003-10-30 | 2006-08-30 | Lupin Ltd. | Stable formulations of ace inhibitors and methods for preparation thereof |
GB2394660A (en) * | 2003-12-17 | 2004-05-05 | Niche Generics Ltd | Stabilisation of pharmaceutical compositions comprising ACE inhibitor by absence of acidic excipients having large specific surface area, eg silicon dioxide |
EA011862B1 (ru) * | 2004-03-24 | 2009-06-30 | Актавис Груп Хф. | Композиции рамиприла |
GB0518129D0 (en) * | 2005-09-06 | 2005-10-12 | Arrow Int Ltd | Ramipril formulation |
GB2431579A (en) * | 2005-10-28 | 2007-05-02 | Arrow Int Ltd | Ramipril formulations |
US20070098782A1 (en) * | 2005-10-28 | 2007-05-03 | Selamine Limited | Ramipril Formulation |
US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
US20070232680A1 (en) * | 2006-04-04 | 2007-10-04 | Vijayabhaskar Bolugoddu | Preparation of ramipril and stable pharmaceutical compositions |
JP2009533461A (ja) * | 2006-04-19 | 2009-09-17 | テバ ファーマシューティカル インダストリーズ リミティド | 2−アザ−ビシクロ[3.3.0]−オクタン−3−カルボン酸誘導体の安定な医薬組成物 |
US8017168B2 (en) * | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
GB0624090D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amine salts |
GB0624084D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amino acid salts |
GB0624087D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril combination salt |
KR100808132B1 (ko) | 2007-03-02 | 2008-02-29 | 고천일 | 음식물쓰레기 소멸처리장치 |
ES2364011B1 (es) | 2009-11-20 | 2013-01-24 | Gp Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares. |
WO2012085249A2 (en) * | 2010-12-24 | 2012-06-28 | Krka, D.D., Novo Mesto | Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts |
US8568747B1 (en) | 2012-10-05 | 2013-10-29 | Silvergate Pharmaceuticals, Inc. | Enalapril compositions |
SMT201900031T1 (it) | 2014-07-31 | 2019-02-28 | Pharmathen Sa | Composizione di film orosolubile comprendente enalapril per il trattamento di ipertensione in una popolazione pediatrica |
US9463183B1 (en) | 2015-10-30 | 2016-10-11 | Silvergate Pharmaceuticals, Inc. | Lisinopril formulations |
US20180325813A1 (en) | 2015-11-07 | 2018-11-15 | Ftf Pharma Private Limited | Oral solution of ace inhibitors |
US9669008B1 (en) | 2016-03-18 | 2017-06-06 | Silvergate Pharmaceuticals, Inc. | Enalapril formulations |
KR20200108023A (ko) | 2018-01-11 | 2020-09-16 | 메리테이지 파마, 인크. | 안정한 코르티코스테로이드 조성물 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE569430A (xx) * | 1957-07-17 | |||
US3697641A (en) * | 1970-01-02 | 1972-10-10 | Gerhard W Ahrens | Nonhygroscopic non-sugarbase noncariogenic-vitamin c releasable base material for use in the preparation of suckable tablets,lozenges and chocolate |
ATE22530T1 (de) * | 1980-07-29 | 1986-10-15 | Sanofi Sa | Durch saeure stabilisierte mischungen von thienopyridinderivaten und verfahren zum verhindern der zersetzung solcher verbindungen. |
US4344949A (en) * | 1980-10-03 | 1982-08-17 | Warner-Lambert Company | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
US4442089A (en) * | 1982-07-06 | 1984-04-10 | E. R. Squibb & Sons, Inc. | Method for treating glaucoma with topical or systemic ACE inhibitor compositions |
US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
US4666705A (en) * | 1985-06-03 | 1987-05-19 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
US4656188A (en) * | 1985-10-09 | 1987-04-07 | Merck & Co., Inc. | Ace inhibitors in macular degeneration |
-
1986
- 1986-10-20 US US06/921,717 patent/US4830853A/en not_active Expired - Lifetime
-
1987
- 1987-09-18 CA CA000547231A patent/CA1297024C/en not_active Expired - Lifetime
- 1987-09-22 IE IE255087A patent/IE60773B1/en not_active IP Right Cessation
- 1987-09-22 ZA ZA877132A patent/ZA877132B/xx unknown
- 1987-09-28 NZ NZ221954A patent/NZ221954A/xx unknown
- 1987-10-06 AU AU79397/87A patent/AU604061B2/en not_active Expired
- 1987-10-16 DK DK198705435A patent/DK174916B1/da not_active IP Right Cessation
- 1987-10-19 JP JP62261931A patent/JP2703906B2/ja not_active Expired - Fee Related
- 1987-10-19 PT PT85942A patent/PT85942B/pt unknown
- 1987-10-19 ES ES198787115281T patent/ES2040726T3/es not_active Expired - Lifetime
- 1987-10-19 NO NO874352A patent/NO874352L/no unknown
- 1987-10-19 FI FI874594A patent/FI100091B/fi not_active IP Right Cessation
- 1987-10-19 DE DE8787115281T patent/DE3772924D1/de not_active Expired - Lifetime
- 1987-10-19 AT AT87115281T patent/ATE67090T1/de not_active IP Right Cessation
- 1987-10-19 EP EP87115281A patent/EP0264887B1/en not_active Expired - Lifetime
- 1987-10-20 KR KR1019870011654A patent/KR960000430B1/ko not_active IP Right Cessation
- 1987-10-20 PH PH35959A patent/PH25582A/en unknown
-
1991
- 1991-09-12 GR GR91401217T patent/GR3002698T3/el unknown
-
1994
- 1994-07-15 SG SG95494A patent/SG95494G/en unknown
- 1994-08-18 HK HK85694A patent/HK85694A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK174916B1 (da) | 2004-02-23 |
JPS63104931A (ja) | 1988-05-10 |
CA1297024C (en) | 1992-03-10 |
FI100091B (fi) | 1997-09-30 |
PT85942A (en) | 1987-11-01 |
KR960000430B1 (ko) | 1996-01-06 |
DE3772924D1 (de) | 1991-10-17 |
US4830853A (en) | 1989-05-16 |
DK543587A (da) | 1988-04-21 |
GR3002698T3 (en) | 1993-01-25 |
PH25582A (en) | 1991-08-08 |
NZ221954A (en) | 1990-03-27 |
IE60773B1 (en) | 1994-08-10 |
PT85942B (pt) | 1990-07-31 |
SG95494G (en) | 1994-10-28 |
NO874352D0 (no) | 1987-10-19 |
EP0264887A1 (en) | 1988-04-27 |
JP2703906B2 (ja) | 1998-01-26 |
DK543587D0 (da) | 1987-10-16 |
FI874594A0 (fi) | 1987-10-19 |
FI874594A (fi) | 1988-04-21 |
IE872550L (en) | 1988-04-20 |
AU7939787A (en) | 1988-04-21 |
ATE67090T1 (de) | 1991-09-15 |
KR880004811A (ko) | 1988-06-27 |
NO874352L (no) | 1988-04-21 |
EP0264887B1 (en) | 1991-09-11 |
AU604061B2 (en) | 1990-12-06 |
ES2040726T3 (es) | 1993-11-01 |
HK85694A (en) | 1994-08-26 |
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